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Author Apicella, C.L.; Marlowe, F.W.; Fowler, J.H.; Christakis, N.A.
Title Social networks and cooperation in hunter-gatherers Type (up) Journal Article
Year 2012 Publication Abbreviated Journal Nature
Volume 481 Issue 7382 Pages 497-501
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Publisher Nature Publishing Group, a division of Macmillan Publishers Limited. All Rights Reserved. Place of Publication Editor
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Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0028-0836 ISBN Medium
Area Expedition Conference
Notes 10.1038/nature10736 Approved no
Call Number Equine Behaviour @ team @ Serial 5577
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Author Ferrero, D.M.; Moeller, L.M.; Osakada, T.; Horio, N.; Li, Q.; Roy, D.S.; Cichy, A.; Spehr, M.; Touhara, K.; Liberles, S.D.
Title A juvenile mouse pheromone inhibits sexual behaviour through the vomeronasal system Type (up) Journal Article
Year 2013 Publication Abbreviated Journal Nature
Volume 502 Issue 7471 Pages 368-371
Keywords Pheromone Olfactory receptors
Abstract Animals display a repertoire of different social behaviours. Appropriate behavioural responses depend on sensory input received during social interactions. In mice, social behaviour is driven by pheromones, chemical signals that encode information related to age, sex and physiological state1. However, although mice show different social behaviours towards adults, juveniles and neonates, sensory cues that enable specific recognition of juvenile mice are unknown. Here we describe a juvenile pheromone produced by young mice before puberty, termed exocrine-gland secreting peptide 22 (ESP22). ESP22 is secreted from the lacrimal gland and released into tears of 2- to 3-week-old mice. Upon detection, ESP22 activates high-affinity sensory neurons in the vomeronasal organ, and downstream limbic neurons in the medial amygdala. Recombinant ESP22, painted on mice, exerts a powerful inhibitory effect on adult male mating behaviour, which is abolished in knockout mice lacking TRPC2, a key signalling component of the vomeronasal organ2, 3. Furthermore, knockout of TRPC2 or loss of ESP22 production results in increased sexual behaviour of adult males towards juveniles, and sexual responses towards ESP22-deficient juveniles are suppressed by ESP22 painting. Thus, we describe a pheromone of sexually immature mice that controls an innate social behaviour, a response pathway through the accessory olfactory system and a new role for vomeronasal organ signalling in inhibiting sexual behaviour towards young. These findings provide a molecular framework for understanding how a sensory system can regulate behaviour.
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Corporate Author Thesis
Publisher Nature Publishing Group, a division of Macmillan Publishers Limited. All Rights Reserved. Place of Publication Editor
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0028-0836 ISBN Medium
Area Expedition Conference
Notes Approved no
Call Number Equine Behaviour @ team @ Serial 5732
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Author Moon, C.; Baldridge, M.T.; Wallace, M.A.; Burnham, C.-A.D.; Virgin, H.W.; Stappenbeck, T.S.
Title Vertically transmitted faecal IgA levels determine extra-chromosomal phenotypic variation Type (up) Journal Article
Year 2015 Publication Nature Abbreviated Journal Nature
Volume 521 Issue 7550 Pages 90-93
Keywords Phenotype
Abstract The proliferation of genetically modified mouse models has exposed phenotypic variation between investigators and institutions that has been challenging to control1-5. In many cases, the microbiota is the presumed culprit of the variation. Current solutions to account for phenotypic variability include littermate and maternal controls or defined microbial consortia in gnotobiotic mice6,7. In conventionally raised mice, the microbiome is transmitted from the dam2,8,9. Here we show that microbially–driven dichotomous fecal IgA levels in WT mice within the same facility mimic the effects of chromosomal mutations. We observed in multiple facilities that vertically-transmissible bacteria in IgA-Low mice dominantly lowered fecal IgA levels in IgA-High mice after cohousing or fecal transplantation. In response to injury, IgA-Low mice showed increased damage that was transferable by fecal transplantation and driven by fecal IgA differences. We found that bacteria from IgA-Low mice degraded the secretory component (SC) of SIgA as well as IgA itself. These data indicate that phenotypic comparisons between mice must take into account the non-chromosomal hereditary variation between different breeders. We propose fecal IgA as one marker of microbial variability and conclude that cohousing and/or fecal transplantation enables analysis of progeny from different dams.
Address Department of Pathology and Immunology, Washington University School of Medicine, St Louis, Missouri 63110, USA.
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Publisher Place of Publication Editor
Language eng Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0028-0836 ISBN Medium
Area Expedition Conference
Notes Approved no
Call Number Equine Behaviour @ team @ Serial 6005
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Author Parr, L.A.; de Waal, F.B.
Title Visual kin recognition in chimpanzees Type (up)
Year 1999 Publication Nature Abbreviated Journal Nature
Volume 399 Issue 6737 Pages 647-648
Keywords Animals; *Behavior, Animal; Face; Female; Male; Pan troglodytes/*physiology
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Language English Summary Language Original Title
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ISSN 0028-0836 ISBN Medium
Area Expedition Conference
Notes PMID:10385114 Approved no
Call Number refbase @ user @ Serial 195
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Author Whiten, A.; McGrew, W.C.
Title Is this the first portrayal of tool use by a chimp? Type (up)
Year 2001 Publication Nature Abbreviated Journal Nature
Volume 409 Issue 6816 Pages 12
Keywords Animals; *Behavior, Animal; Pan troglodytes/*physiology; Philately
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Language English Summary Language Original Title
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ISSN 0028-0836 ISBN Medium
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Notes PMID:11343083 Approved no
Call Number refbase @ user @ Serial 739
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Author Dyer, F.C.
Title Animal behaviour: when it pays to waggle Type (up)
Year 2002 Publication Nature Abbreviated Journal Nature
Volume 419 Issue 6910 Pages 885-886
Keywords *Animal Communication; Animals; Bees/*physiology; California; Dancing/physiology; Environment; Evolution; Female; Flowers/chemistry; *Food; Gravitation; Lighting; Motor Activity/*physiology; Odors; Seasons; Sunlight
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Language English Summary Language Original Title
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ISSN 0028-0836 ISBN Medium
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Notes PMID:12410290 Approved no
Call Number refbase @ user @ Serial 769
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Author McGonigle, B.
Title Can apes learn to count? Type (up)
Year 1985 Publication Nature Abbreviated Journal Nature
Volume 315 Issue 6014 Pages 16-17
Keywords Animals; Behavior, Animal/physiology; Cognition; Pan troglodytes/*physiology
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Language English Summary Language Original Title
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ISSN 0028-0836 ISBN Medium
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Notes PMID:3990806 Approved no
Call Number Equine Behaviour @ team @ Serial 2794
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Author Bell, A.M.
Title Evolutionary biology: animal personalities Type (up)
Year 2007 Publication Nature Abbreviated Journal Nature
Volume 447 Issue 7144 Pages 539-540
Keywords Aggression/physiology/psychology; Animals; Behavior, Animal/*physiology; *Evolution; Humans; *Models, Biological; Personality/genetics/*physiology; Reproduction/genetics/physiology; Risk-Taking; Selection (Genetics)
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Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1476-4687 ISBN Medium
Area Expedition Conference
Notes PMID:17538607 Approved no
Call Number Equine Behaviour @ team @ Serial 4099
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