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Author Williams, D.O.; Boatwright, R.B.; Rugh, K.S.; Garner, H.E.; Griggs, D.M.J.
Title Myocardial blood flow, metabolism, and function with repeated brief coronary occlusions in conscious ponies Type Journal Article
Year (up) 1991 Publication The American journal of physiology Abbreviated Journal Am J Physiol
Volume 260 Issue 1 Pt 2 Pages H100-9
Keywords Animals; Consciousness/*physiology; Coronary Circulation/*physiology; Coronary Disease/pathology/*physiopathology; Disease Models, Animal; Hemodynamic Processes/physiology; Horses/*physiology; Hydrogen/metabolism; Lactates/metabolism; Myocardium/*metabolism/pathology; Norepinephrine/metabolism; Potassium/metabolism; Regional Blood Flow
Abstract Studies were performed in the conscious pony instrumented with a Doppler flow probe and hydraulic occluder on the left anterior descending coronary artery (LAD), sonomicrometry crystals and intraventricular micromanometer in the left ventricle, and catheters in the left atrium and anterior interventricular vein. Two-minute LAD occlusions were performed every 30 min continuously or during working hours. Data on release of catabolites (potassium, hydrogen ions, and lactate) and norepinephrine from the initially dysfunctional region were obtained periodically during a regimen of 445 +/- 56 occlusions in six animals. Regional myocardial blood flow was measured (microsphere method) before and after an occlusion regimen in four animals. Marked release of catabolites and norepinephrine from the initially dysfunctional region was noted in association with early occlusions when myocardial segment function was severely reduced. With further occlusions, release of these substances decreased while segment function improved. Blood flow was markedly decreased in the initially dysfunctional region during an early occlusion but was at the control level during a later occlusion. Although the metabolic findings are consistent with protection due to “ischemic preconditioning” and no increase in collateral perfusion, the inverse relationship noted between catabolite release and segment function is best explained by flow-dependent mechanisms. These results, together with the myocardial blood flow data, serve to validate a previous assumption that protection against regional myocardial dysfunction under these conditions is due to increased collateral perfusion.
Address Department of Physiology, University of Missouri, Columbia 65212
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0002-9513 ISBN Medium
Area Expedition Conference
Notes PMID:1992786 Approved no
Call Number refbase @ user @ Serial 98
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Author Schwarzenberger, F.; Mostl, E.; Bamberg, E.; Pammer, J.; Schmehlik, O.
Title Concentrations of progestagens and oestrogens in the faeces of pregnant Lipizzan, trotter and thoroughbred mares Type Journal Article
Year (up) 1991 Publication Journal of reproduction and fertility. Supplement Abbreviated Journal J Reprod Fertil Suppl
Volume 44 Issue Pages 489-499
Keywords Animals; Estrogens/*analysis; Feces/*chemistry; Female; Gestational Age; Horses/*metabolism; Immunoenzyme Techniques; Labor, Obstetric; Pregnancy; Pregnancy, Animal/*metabolism; Pregnenes/analysis; Progestins/*analysis
Abstract Faecal samples were collected at weekly intervals from pregnant Lipizzan mares during Weeks 7-16 following mating and from Lipizzan, Trotter and Thoroughbred mares during the last 3 months of gestation. After parturition, samples were taken daily from the Thoroughbred mares for another 6 days. Non-pregnant mares served as controls. The concentrations of unconjugated oestrogens (Eg), 20 alpha-OH-progestagens (20 alpha-G) and 20 beta-OH-progestagens (20 beta-G) were measured by enzyme immunoassay. In the faeces of Lipizzan mares, immunoreactive progestagens were significantly (P less than 0.01) elevated above the levels in non-pregnant mares by Week 11, and Eg by Week 13 of pregnancy onwards. During the last 3 months of gestation, concentrations of Eg were significantly higher in Trotter mares than in Lipizzan and Thoroughbred mares. Concentrations of 20 alpha-G and 20 beta-G increased to maximal values in the last month of gestation. There was no significant difference among the 3 breeds with respect to 20 alpha-G but, during the 10 weeks before parturition, concentrations of 20 beta-G in the Lipizzan mares were significantly lower (P less than 0.05) than those in the Thoroughbred mares. They were also significantly lower than those of the Trotter mares during the last 4 weeks of gestation. After parturition, the concentrations of Eg and progestagens had declined to baseline values by Days 3 and 4 respectively. From these results we conclude that high concentrations of progestagens with 20 alpha- and 20 beta-hydroxyl groups are present in the faeces of pregnant mares, especially during the last month of gestation.
Address Institut fur Biochemie, Veterinary Medical University, Vienna, Austria
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0449-3087 ISBN Medium
Area Expedition Conference
Notes PMID:1795293 Approved no
Call Number refbase @ user @ Serial 322
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Author Dougherty, D.M.; Lewis, P.
Title Stimulus generalization, discrimination learning, and peak shift in horses Type Journal Article
Year (up) 1991 Publication Journal of the experimental analysis of behavior Abbreviated Journal J Exp Anal Behav
Volume 56 Issue 1 Pages 97-104
Keywords Animals; *Appetitive Behavior; Attention; *Conditioning, Operant; *Discrimination Learning; Female; *Generalization, Stimulus; Horses/*psychology; Male; *Pattern Recognition, Visual; Size Perception
Abstract Using horses, we investigated three aspects of the stimulus control of lever-pressing behavior: stimulus generalization, discrimination learning, and peak shift. Nine solid black circles, ranging in size from 0.5 in. to 4.5 in. (1.3 cm to 11.4 cm) served as stimuli. Each horse was shaped, using successive approximations, to press a rat lever with its lip in the presence of a positive stimulus, the 2.5-in. (6.4-cm) circle. Shaping proceeded quickly and was comparable to that of other laboratory organisms. After responding was maintained on a variable-interval 30-s schedule, stimulus generalization gradients were collected from 2 horses prior to discrimination training. During discrimination training, grain followed lever presses in the presence of a positive stimulus (a 2.5-in circle) and never followed lever presses in the presence of a negative stimulus (a 1.5-in. [3.8-cm] circle). Three horses met a criterion of zero responses to the negative stimulus in fewer than 15 sessions. Horses given stimulus generalization testing prior to discrimination training produced symmetrical gradients; horses given discrimination training prior to generalization testing produced asymmetrical gradients. The peak of these gradients shifted away from the negative stimulus. These results are consistent with discrimination, stimulus generalization, and peak-shift phenomena observed in other organisms.
Address Department of Psychology, Ohio University, Athens 45701
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0022-5002 ISBN Medium
Area Expedition Conference
Notes PMID:1940765 Approved no
Call Number Serial 1764
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Author Krzak, W.E.; Gonyou, H.W.; Lawrence, L.M.
Title Wood chewing by stabled horses: diurnal pattern and effects of exercise Type Journal Article
Year (up) 1991 Publication Journal of Animal Science Abbreviated Journal J. Anim Sci.
Volume 69 Issue 3 Pages 1053-1058
Keywords Animal Feed; Animals; *Behavior, Animal; *Circadian Rhythm; Female; Horses/*physiology; Male; *Mastication; *Physical Conditioning, Animal; Sodium Chloride/administration & dosage; Videotape Recording; Wood
Abstract Nine yearling horses, stabled in individual stalls, were used in a trial to determine the diurnal pattern of wood chewing and the effects of exercise on this behavior. The trial was a Latin square design conducted over three 2-wk periods during which each horse was exposed to each of the three following treatments: 1) no exercise (NE), 2) exercise after the morning feeding (AM), and 3) exercise in the afternoon (PM). Horses were fed a complete pelleted feed in the morning and both pelleted feed and long-stemmed hay in the afternoon. Exercise consisted of 45 min on a mechanical walker followed by 45 min in a paddock with bare soil. Each stall was equipped with two untreated spruce boards during each period for wood chewing. Wood chewing was evaluated by videotaping each horse for 22 h during each period, determining the weight and volume of the boards before and after each period, and by visual appraisal of the boards. Intake of trace mineralized salt was also measured. Wood chewing occurred primarily between 2200 and 1200. All measures of wood chewing were correlated when totals for the entire 6 wk were analyzed. When analysis was performed on 2-wk values, videotape results were not correlated with volume or weight loss of boards. Horses chewed more when on the NE treatment (511 s/d) than when on AM or PM (57 and 136 s/d, respectively; P less than .05). Salt intake tended to be greater for NE than for the other treatments (P less than .10).(ABSTRACT TRUNCATED AT 250 WORDS)
Address Dept. of Anim. Sci., University of Illinois, Urbana 61801
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0021-8812 ISBN Medium
Area Expedition Conference
Notes PMID:2061237 Approved no
Call Number refbase @ user @ Serial 1949
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Author Gill, J.
Title A new method for continuous recording of motor activity in horses Type Journal Article
Year (up) 1991 Publication Comparative Biochemistry and Physiology. A, Comparative Physiology Abbreviated Journal Comp Biochem Physiol A
Volume 99 Issue 3 Pages 333-341
Keywords Animals; Circadian Rhythm; Female; Horses/*physiology; Monitoring, Physiologic/instrumentation/*veterinary; *Motor Activity; Signal Processing, Computer-Assisted
Abstract 1. The use of an electronic recorder for the horse motor activity was described. 2. Examples of different types of motor activities are given in Figs 1-8. 3. The ultradian pattern of activity in all records was stressed. 4. The possibility of receiving of more physiological informations by this type of apparatus is discussed.
Address Department of Vertebrate Animal Physiology, University of Warsaw, Poland
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0300-9629 ISBN Medium
Area Expedition Conference
Notes PMID:1678331 Approved no
Call Number refbase @ user @ Serial 1950
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Author Lucas, Z.; Raeside, J.I.; Betteridge, K.J.
Title Non-invasive assessment of the incidences of pregnancy and pregnancy loss in the feral horses of Sable Island Type Journal Article
Year (up) 1991 Publication Journal of Reproduction and Fertility. Supplement Abbreviated Journal J Reprod Fertil Suppl
Volume 44 Issue Pages 479-488
Keywords Abortion, Veterinary/*epidemiology; Animals; Animals, Wild/*physiology; Atlantic Islands; Estrogens/analysis; Feces/chemistry; Female; Fertilization; Gestational Age; Horse Diseases/*epidemiology; Horses; Incidence; Pregnancy; *Pregnancy, Animal
Abstract Field observations of 400 totally unmanaged feral horses on Sable Island, Nova Scotia, were complemented by oestrogen determinations in faecal samples from 154 identified females over a 4-year period (454 mare-years). Of mares that were sampled throughout the year and subsequently produced foals, 92.1% exhibited elevated faecal oestrogens between 15 October and 30 March. The results confirm that faecal oestrogens are a useful indicator of pregnancy after approximately 120 days gestation. Distribution of foaling resembled that seen in other feral populations, with 95% of births occurring from April through July. The foaling rate for mares aged 3 years or older was 62.0%, with 50.7% of mares foaling in 3 or 4 years. Foaling rates were low (4.1%) in mares bred as yearlings and rose with age to 70.8% in those bred as 4-year-olds. Fetal loss after Day 120 was deduced from faecal oestrogens to be 26.0% overall, with marked variation from year to year (9.6-37.3%) and with age (70.0% in those bred as yearlings, decreasing to 5.6% in those bred as 4-year-olds). Of 58 mares aged 2 years or older that were sampled every year, about half (49.6%) the barren years were attributable to fetal loss after 120 days gestation. All mares conceived in at least 2 of the 4 years, suggesting that pregnancy loss, even after Day 120, is as important as failure to conceive in causing barren years.
Address Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph, Canada
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0449-3087 ISBN Medium
Area Expedition Conference
Notes PMID:1795292 Approved no
Call Number Equine Behaviour @ team @ Serial 2247
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Author Jablonska, E.M.; Ziolkowska, S.M.; Gill, J.; Szykula, R.; Faff, J.
Title Changes in some haematological and metabolic indices in young horses during the first year of jump-training Type Journal Article
Year (up) 1991 Publication Equine Veterinary Journal Abbreviated Journal Equine Vet J
Volume 23 Issue 4 Pages 309-311
Keywords Alanine Transaminase/blood; Animals; Bicarbonates/blood; Blood Glucose/analysis; Blood Proteins/analysis; Breeding; Carbon Dioxide/blood; Exercise Test/veterinary; Fatty Acids, Nonesterified/blood; Female; Fructose-Bisphosphate Aldolase/blood; Hematocrit/veterinary; Hemoglobins/analysis; Horses/*blood/metabolism; Hydrogen-Ion Concentration; Lactates/blood; Male; Oxygen/blood; *Physical Conditioning, Animal; Pyruvates/blood
Abstract Effects of an 18 min exercise test, on three separate occasions during a one year jump-training programme, was studied in seven horses. Determinations were carried out on venous blood for packed cell volume, haemoglobin, total protein, lactate and pyruvate, glucose, free fatty acids, insulin, glucagon, blood gases, bicarbonate, pH, aldolase, aspartate aminotransferase and alanine amino-transferase. Exercise caused a slight increase in lactate and pyruvate, total protein, aldolase, alanine aminotransferase, pO2, bicarbonate and pH. Glucose, free fatty acids and pCO2 levels decreased. Training caused no significant difference in these changes. However, during the year, increases in lactate and decreases in pH (resting levels) were observed.
Address Department of Vertebrate Animal Physiology, Warszawa, Poland
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0425-1644 ISBN Medium
Area Expedition Conference
Notes PMID:1915234 Approved no
Call Number Equine Behaviour @ team @ Serial 3801
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Author Scheidhacker, M.; Bender, W.; Vaitl, P.
Title Die Wirksamkeit des therapeutischen Reitens bei der Behandlung chronisch schizophrener Patienten Type Journal Article
Year (up) 1991 Publication Der Nervenarzt Abbreviated Journal Nervenarzt
Volume 62 Issue 5 Pages 283-287
Keywords Adaptation, Psychological; Adult; Animals; Attention; Chronic Disease; Female; Follow-Up Studies; *Horses; Humans; Male; Psychiatric Status Rating Scales; Psychotherapy/*methods; Schizophrenia/*rehabilitation; *Schizophrenic Psychology; Self Concept; *Sports
Abstract After describing horse-riding as a facility in managing mentally ill patients, a program for chronic schizophrenic in-patients is presented. Clinical experience with this program and also results of a controlled study are reported. The therapeutic value and slope for horse-riding are discussed in relation to different diagnoses.
Address Bezirkskrankenhaus Haar b. Munchen
Corporate Author Thesis
Publisher Place of Publication Editor
Language German Summary Language Original Title Die Wirksamkeit des therapeutischen Reitens bei der Behandlung chronisch schizophrener Patienten. Experimentelle Ergebnisse und klinische Erfahrungen
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0028-2804 ISBN Medium
Area Expedition Conference
Notes [The effectiveness of therapeutic horseback-riding in the treatment of chronic schizophrenic patients. Experimental results and clinical experiences] Approved no
Call Number Equine Behaviour @ team @ Serial 5067
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Author Kirkpatrick, J.F.; Liu, I.M.; Turner, J.W.J.; Naugle, R.; Keiper, R.
Title Long-term effects of porcine zonae pellucidae immunocontraception on ovarian function in feral horses (Equus caballus) Type Journal Article
Year (up) 1992 Publication Journal of reproduction and fertility Abbreviated Journal J Reprod Fertil
Volume 94 Issue 2 Pages 437-444
Keywords Animals; Contraception, Immunologic/*veterinary; *Egg Proteins; Estrogens, Conjugated (USP)/urine; Female; Glycoproteins/*pharmacology; Horses/immunology/*physiology; *Membrane Glycoproteins; Ovary/drug effects/*physiology; Progesterone/metabolism; *Receptors, Cell Surface; Swine/immunology; Time Factors; Zona Pellucida/*immunology
Abstract Ten feral mares free-roaming in Maryland, USA, were inoculated with porcine zonae pellucidae (PZP) protein before the breeding season for three consecutive years (1988-90). Ovarian function was monitored for 51 days during the peak of the breeding season after the third annual PZP inoculation, in seven of these mares and in four untreated control mares, by means of urinary oestrone conjugates and nonspecific progesterone metabolites. None of the ten inoculated mares became pregnant in 1990, compared with 55% of 20 control mares, which included two of the four monitored for ovarian function. Three of the untreated mares demonstrated apparent normal ovarian activity, characterized by preovulatory oestrogen peaks, concurrent progesterone nadirs at ovulation, breeding activity, and luteal-phase progesterone increases after ovulation. Two of the seven monitored PZP-treated mares demonstrated ovulatory cycles that did not result in conception. One was pregnant as a result of conception in 1989 and demonstrated a normal, late-gestation, endocrine profile. The remaining four PZP-treated mares revealed no evidence of ovulation, and urinary oestrogen concentrations were significantly depressed. The experiments indicated that (i) a third consecutive annual PZP booster inoculation is greater than 90% effective in preventing pregnancies in mares and (ii) three consecutive years of PZP treatment may interfere with normal ovarian function as shown by markedly depressed oestrogen secretion.
Address Deaconess Research Institute, Billings, MT 59102
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0022-4251 ISBN Medium
Area Expedition Conference
Notes PMID:1317449 Approved no
Call Number refbase @ user @ Serial 145
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Author Kraus-Hansen, A.E.; Fackelman, G.E.; Becker, C.; Williams, R.M.; Pipers, F.S.
Title Preliminary studies on the vascular anatomy of the equine superficial digital flexor tendon Type Journal Article
Year (up) 1992 Publication Equine veterinary journal Abbreviated Journal Equine Vet J
Volume 24 Issue 1 Pages 46-51
Keywords Angiography/veterinary; Animals; Exercise Test/veterinary; Forelimb; Horses/*anatomy & histology/surgery; Microcirculation; Microscopy, Electron, Scanning; Tendons/*blood supply/surgery/ultrastructure
Abstract The vascular and microvascular anatomy of normal equine superficial digital flexor tendons was studied by dissection of vinyl-perfused specimens and by microangiography on high detail film. The presence of an extensive intratendinous vascular latticework was confirmed, and a 'nutrient artery' described closely associated with the accessory ligament of the superficial digital flexor tendon (proximal check ligament). Circumferential stripping of the paratenon from the tendon to eliminate afferent vessels was performed bilaterally in three horses and unilaterally in a fourth, followed by a treadmill training regimen. No resulting intratendinous lesions could be documented on gross post mortem and histological examination at three, 10, or 35 days post operatively. There was mild paratendinous proliferation in all instances. In one horse, four intratendinous ligatures were placed within the medial and lateral borders of the contralateral tendon to isolate further from its blood supply a 10 cm segment. Gross lesions at 35 days post operatively included a marked paratendinous response involving the entire 10 cm segment, and a darkened, soft focus within the core of the tendon. Histopathology and electron microscopy demonstrated focal degeneration. It was concluded that the blood supply of the normal equine superficial digital flexor tendon is primarily intratendinous, rather than paratendinous as previously thought. The lesions in one horse similar to those in naturally occurring tendinitis supported a vascular aetiology of the disease, and set the groundwork for studies aimed at the development of a clinically relevant tendinitis model.
Address Department of Surgery, Tufts University School of Veterinary Medicine, North Grafton, Massachusetts 01536
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0425-1644 ISBN Medium
Area Expedition Conference
Notes PMID:1555540 Approved no
Call Number refbase @ user @ Serial 151
Permanent link to this record