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Author Seralini G.-E.; Moslemi S.
Title Aromatase inhibitors: past, present and future Type Journal Article
Year 2001 Publication Molecular and Cellular Endocrinology Abbreviated Journal
Volume (down) 178 Issue Pages 117-131
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Notes Approved no
Call Number refbase @ user @ Serial 2014
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Author Pinchbeck, G.L.; Clegg, P.D.; Proudman, C.J.; Stirk, A.; Morgan, K.L.; French, N.P.
Title Horse injuries and racing practices in National Hunt racehorses in the UK: the results of a prospective cohort study Type Journal Article
Year 2004 Publication The Veterinary Journal Abbreviated Journal
Volume (down) 167 Issue 1 Pages 45-52
Keywords Racehorse; Horse; Injury; Cohort; National Hunt
Abstract A prospective cohort study was conducted on horses starting in hurdle and steeplechase races on six UK racecourses in 2000 and 2001. Trainers or carers were questioned on the horses' pre-race routine and observational data were collected in the stables and parade ring. Some practices were common to many starters, such as withholding food and water before racing whereas other practices, such as schooling frequency, were more variable. There was a total of 2879 starts and a total of 83 injuries or medical events (28.8/1000 starts). The commonest types of injury were tendon/suspensory injuries and lacerations/wounds. Multivariable logistic regression models were used to identify the relationship between predictor variables and the risk of injury. Risk of injury or medical event was associated with distance of the race and weight carried. The risk of injury, excluding medical events, was associated with the speed of the race and foot conformation.
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Notes Approved no
Call Number Equine Behaviour @ team @ Serial 3672
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Author Shen, Y.-Q.; Hebert, G.; Lin, L.-Y.; Luo, Y.-L.; Moze, E.; Li, K.-S.; Neveu, P.J.
Title Interleukine-1β and interleukine-6 levels in striatum and other brain structures after MPTP treatment: influence of behavioral lateralization Type Journal Article
Year 2005 Publication Journal of Neuroimmunology Abbreviated Journal
Volume (down) 158 Issue 1–2 Pages 14-25
Keywords N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Dopamine; Brain; Interleukin-6; Interleukin-1β; Behavioral lateralization
Abstract MPTP (N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) induces diminution of the dopamine in nigrostriatal pathway and cognitive deficits in mice. MPTP treatment also increases pro-inflammatory cytokine production in substantia nigra and striatum. Since, pro-inflammatory cytokines influence striatal dopamine content and provoke cognitive impairments, the cognitive defects induced by MPTP may be partly due to brain cytokine induction in other structures than nigrostriatal pathway. Furthermore, behavioral lateralization, as assessed by paw preference, influences cytokine production at the periphery and in the central nervous system. Behavioral lateralization may thus influence brain cytokine levels after MPTP. In order to address these issues, mice selected for paw preference were injected with 25 mg/kg MPTP i.p. for five consecutive days after which striatal dopamine and DOPAC contents were measured by HPLC and IL-1β and IL-6 quantified by ELISA in the striatum, cerebral cortex, hippocampus and hypothalamus. The results showed that MPTP treatment induced dramatic loss of DA in striatum, simultaneously, IL-6 levels decreased in the striatum and increased in hippocampus and hypothalamus, while IL-1β levels decreased in the striatum, cerebral cortex and hippocampus. Interestingly, striatal dopamine turnover under basal conditions as well as striatal IL-1β and IL-6 levels under basal conditions and after MPTP depended on behavioral lateralization. Left pawed mice showed a higher decrease in dopamine turnover and lower cytokine levels as compared to right pawed animals. Behavioral lateralization also influenced IL-6 hippocampal levels under basal conditions and IL-1β cortical levels after MPTP. From these results, it can be concluded that MPTP-induced cognitive defects are accompanied by an alteration of pro-inflammatory cytokine levels in brain structures other than those involved in the nigrostriatal pathway. In addition, MPTP-induced dopamine decrease is influenced by behavioral lateralization, possibly through an effect on brain cytokine levels.
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ISSN 0165-5728 ISBN Medium
Area Expedition Conference
Notes Approved no
Call Number Equine Behaviour @ team @ Serial 5781
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Author Pinchbeck, G.L.; Clegg, P.D.; Proudman, C.J.; Morgan, K.L.; French, N.P.
Title Case-control investigation of the factors affecting the risk of horses falling during steeplechase racing in the UK Type Journal Article
Year 2004 Publication The Veterinary Record Abbreviated Journal Vet. Rec.
Volume (down) 155 Issue 1 Pages 11-15
Keywords Accidental Falls/*prevention & control/*statistics & numerical data; Animals; Athletic Injuries/epidemiology/etiology/prevention & control/*veterinary; Case-Control Studies; England/epidemiology; Horses/*injuries; Risk Factors; Running/*injuries
Abstract A concurrent case-control study of 12 UK racecourses was made between March 1, 2000, and August 31, 2001, to identify and quantify the factors associated with the risk of horses falling in steeplechase races. Cases were defined as a jumping effort at a steeplechase fence that resulted in a fall and controls were defined as a successful jumping effort over any steeplechase fence at any of the 12 racecourses within 14 days before or after the case fall. Information on the horse, the jockey and the race were collected and all the fences on all the courses were surveyed. Conditional logistic regression was used to examine the relationships between the predictor variables and the risk of falling. There was one fall per 254 jumping efforts. The risk of a horse falling decreased the more times it had raced on a particular racecourse. The number of fences, the distance from the previous fence and the nature of the previous fence also affected the risk of falling. If the previous fence was a water jump the risk of falling increased; fences that were sited on flat or slight uphill gradients (up to approximately 1 in 25) were associated with a lower risk of horses falling than downhill fences, and higher takeoff boards were associated with a higher risk of falling.
Address Department of Veterinary Clinical Science, University of Liverpool, Leahurst, Neston CH64 7TE
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Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0042-4900 ISBN Medium
Area Expedition Conference
Notes PMID:15264483 Approved no
Call Number Equine Behaviour @ team @ Serial 3773
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Author Bigiani, A.; Mucignat-Caretta, C.; Montani, G.; Tirindelli, R.
Title Pheromone reception in mammals Type Journal Article
Year 2005 Publication Reviews of Physiology, Biochemistry and Pharmacology Abbreviated Journal
Volume (down) 154 Issue Pages 1-35
Keywords
Abstract Pheromonal communication is the most convenient way to transfer information regarding gender and social status in animals of the same species with the holistic goal of sustaining reproduction. This type of information exchange is based on pheromones, molecules often chemically unrelated, that are contained in body fluids like urine, sweat, specialized exocrine glands, and mucous secretions of genitals. So profound is the relevance of pheromones over the evolutionary process that a specific peripheral organ devoted to their recognition, namely the vomeronasal organ of Jacobson, and a related central pathway arose in most vertebrate species. Although the vomeronasal system is well developed in reptiles and amphibians, most mammals strongly rely on pheromonal communication. Humans use pheromones too; evidence on the existence of a specialized organ for their detection, however, is very elusive indeed. In the present review, we will focus our attention on the behavioral, physiological, and molecular aspects of pheromone detection in mammals. We will discuss the responses to pheromonal stimulation in different animal species, emphasizing the complicacy of this type of communication. In the light of the most recent results, we will also discuss the complex organization of the transduction molecules that underlie pheromone detection and signal transmission from vomeronasal neurons to the higher centers of the brain. Communication is a primary feature of living organisms, allowing the coordination of different behavioral paradigms among individuals. Communication has evolved through a variety of different strategies, and each species refined its own preferred communication medium. From a phylogenetic point of view, the most widespread and ancient way of communication is through chemical signals named pheromones: it occurs in all taxa, from prokaryotes to eukaryotes. The release of specific pheromones into the environment is a sensitive and definite way to send messages to other members of the same species. Therefore, the action of an organism can alter the behavior of another organism, thereby increasing the fitness of either or both. Albeit slow in transmission and not easily modulated, pheromones can travel around objects in the dark and over long distances. In addition, they are emitted when necessary and their biosynthesis is usually economic. In essence, they represent the most efficient tool to refine the pattern of social behaviors and reproductive strategies. © Springer-Verlag 2005.
Address Università di Parma, Dipartimento di Neuroscienze, Sezione di Fisiologia, Via Volturno 39, 43100 Parma, Italy
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Notes Approved no
Call Number Equine Behaviour @ team @ Serial 4570
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Author Dumont, B.; Rossignol, N.; Loucougaray, G.; Carrère, P.; Chadoeuf, J.; Fleurance, G.; Bonis, A.; Farruggia, A.; Gaucherand, S.; Ginane, C.; Louault, F.; Marion, B.; Mesléard, F.; Yavercovski, N.
Title When does grazing generate stable vegetation patterns in temperate pastures? Type Journal Article
Year 2012 Publication Agriculture, Ecosystems & Environment Abbreviated Journal
Volume (down) 153 Issue Pages 50-56
Keywords Boolean process; Cattle; Patch stability; Productivity; Stocking density; Temperate pasture
Abstract The stability of grazing-induced spatial patterns of vegetation was analyzed at two spatial scales (25 m × 20 m areas and 1.6 m × 0.8 m grids) in pastures of contrasting productivity (maximum standing biomass: 130–800 gDM/m2). At both scales, the mosaic of grazed and ungrazed patches was modeled as a Boolean process, calculating cross-variograms to quantify the temporal stability of grazing patterns and its links with local floristic composition were tested. The scale at which stability of vegetation patterns took place in two successive years depended on pasture productivity. Inter-annual stability of large-scale patterns mainly occurred in extensively used fertile pastures grazed by cattle, and in pastures grazed by horses. Less-fertile grasslands were mainly characterized by a fine-scale stability of grazing patterns. Stable fine-scale patterns were often related to the local abundance of legumes and forbs. Stable large-scale patterns of grazing within lightly grazed productive grasslands could result in divergent local vegetation dynamics, which can be seen as an opportunity for restoring biodiversity in fertile grasslands.
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ISSN 0167-8809 ISBN Medium
Area Expedition Conference
Notes Approved no
Call Number Equine Behaviour @ team @ Serial 5595
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Author Quaranta, A.; Siniscalchi, M.; Frate, A.; Vallortigara, G.
Title Paw preference in dogs: relations between lateralised behaviour and immunity Type Journal Article
Year 2004 Publication Behavioural Brain Research Abbreviated Journal
Volume (down) 153 Issue 2 Pages 521-525
Keywords Paw preference; Lateralisation; Immunity; Dog
Abstract Paw use in a task consisting of the removal of a piece of adhesive paper from the snout was investigated in 80 mongrel and pure-bred domestic dogs (Canis familiaris). Population lateralisation was observed, but in opposite directions in the two sexes (animals were not desexed): males preferentially used their left paw, females their right paw. The relationship between immune function and paw preference was then investigated. Some immune parameters (total number of white blood cells including lymphocytes, granulocytes and monocytes; leukocyte formula; total proteins; γ-globulins) were investigated in a sample of left-pawed (n=6), right-pawed (n=6) and ambidextrous (n=6) dogs. The results showed that the percentage of lymphocytes was higher in left-pawed than in right-pawed and ambidextrous dogs, whereas granulocytes percentage was lower in left-pawed than in right-pawed and ambidextrous dogs. Moreover, total number of lymphocytes cells was higher in left-pawed than in right-pawed and ambidextrous dogs, whereas the number of γ-globulins was lower in left-pawed than in right-pawed and ambidextrous dogs. These findings represent the first evidence that brain asymmetry modulates immune responses in dogs.
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ISSN 0166-4328 ISBN Medium
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Notes Approved no
Call Number Equine Behaviour @ team @ Serial 5783
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Author Pinchbeck, G.L.; Clegg, P.D.; Proudman, C.J.; Morgan, K.L.; French, N.P.
Title Case-control study to investigate risk factors for horse falls in hurdle racing in England and Wales Type Journal Article
Year 2003 Publication The Veterinary Record Abbreviated Journal Vet. Rec.
Volume (down) 152 Issue 19 Pages 583-587
Keywords Accidental Falls/*statistics & numerical data; Animals; Athletic Injuries/epidemiology/etiology/*veterinary; Case-Control Studies; England/epidemiology; Horses/*injuries; Risk Factors; Running/injuries; Wales/epidemiology
Abstract Between March 1, 2000 and August 31, 2001, a case-control study was conducted on 12 racecourses in England and Wales to identify and quantify the risk factors associated with horse falls in hurdle races. The cases and controls were defined so that variables relating to the horse, the jockey, the race and racecourse, and the jump could be considered. The cases were defined as a jumping effort at a hurdle flight that resulted in a fall, and the controls were defined as a successful jump over a hurdle at any of the 12 racecourses within 14 days before or after the case fall. Conditional logistic regression was used to examine the univariable and multivariable relationships between the predictor variables and the risk of falling. The risk of falling was significantly associated with the position of the jump in the race, and with the distance and speed of the race. A horse's previous racing experience and history were also significantly associated with the risk of falling and horses participating in their first hurdle race were at almost five times greater risk of falling than horses that had hurdled before.
Address Epidemiology Group, Department of Veterinary Clinical Science and Animal Husbandry, University of Liverpool, Leahurst, Neston CH64 7TE
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Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
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ISSN 0042-4900 ISBN Medium
Area Expedition Conference
Notes PMID:12762486 Approved no
Call Number Equine Behaviour @ team @ Serial 3782
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Author Ionita, J.C.; Poncet, P.A.; Doherr, M.G.; Steiger, A.
Title [Evaluation of the quality of husbandry of Franches-Montagnes horses in their breeding farms] Type Journal Article
Year 2006 Publication Schweizer Archiv fur Tierheilkunde Abbreviated Journal Schweiz Arch Tierheilkd
Volume (down) 148 Issue 4 Pages 191-197
Keywords Animal Husbandry/methods/*standards/statistics & numerical data; *Animal Welfare; Animals; Breeding/*methods/standards; Female; Floors and Floorcoverings; Horses/*physiology; Housing, Animal/*standards; Male; Poaceae; Questionnaires; Social Behavior; Switzerland
Abstract The quality of husbandry of Franches-Montagnes horses (FM) in Switzerland is evaluated on the basis of an investigation carried out in 2002 by the Swiss FM breeding federation. Questionnaires were sent to 3500 of its members and the results include data from 968 breeding enterprises, housing a total of 3965 FM: 46.1% were breeding mares (61.0% with foal at foot), 26.5% young stock, 1.3% stallions and 26.0% non breeding stock (74.6% of which were pleasure horses and 25.4% working horses). 57.6% of the FM were housed in individual boxes with or without permanent outdoor access, 25.4% were hold in groups with or without permanent outdoor access, the remaining 17.0% were kept in standing stalls. 95.0% of the FM had at least visual contact with other equines and 99.2% had sufficient light in their stable. 88.1% were stabled on long stalk straw, while only 4.3% were bedded on other materials other than straw. The average time spent at pasture per horse and per week ranged from 96.5 +/- 51.6 hours in summer to 27.2 +/- 26.7 hours in winter. On average, a FM is used for 8.3 +/- 6.5 hours per week. Horses with an paddock at their disposal spend an average of 39.8 +/- 45.9 hours there per week.
Address Chirurgische Tierklinik, Universitat Leipzig
Corporate Author Thesis
Publisher Place of Publication Editor
Language French Summary Language Original Title Les conditions de detention des chevaux de race franches-montagnes dans leurs exploitations d'elevage
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0036-7281 ISBN Medium
Area Expedition Conference
Notes PMID:16703760 Approved no
Call Number Serial 1872
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Author Poncet, P.A.; Ionita, J.C.; Doherr, M.G.; Steiger, A.
Title [The influence of the socio-economic structure of the breeding farms of Franches-Montagnes horses on the conditions of husbandry] Type Journal Article
Year 2006 Publication Schweizer Archiv fur Tierheilkunde Abbreviated Journal Schweiz Arch Tierheilkd
Volume (down) 148 Issue 4 Pages 183-189
Keywords Altitude; Animal Husbandry/methods/*standards; Animals; Breeding/*economics/standards; Demography; Female; Horses/*physiology; Housing, Animal/*standards; Male; Physical Conditioning, Animal/methods/*physiology; Questionnaires; Social Behavior; Socioeconomic Factors; Switzerland
Abstract The socio-economic structure of the breeding farms of Franches-Montagnes horses (FM) in Switzerland is evaluated on the basis of an investigation carried out in 2002 by the Swiss FM breeding federation. Questionnaires were sent to 3500 of its members and the results include data from 968 breeding enterprises, housing a total of 3965 FM. The quality of the husbandry of FM varies according to factors such as the altitude and the geographical situation of the farms and studs. Socio-economic parameters, such as the role of FM in the business, their use (breeding, driving, riding) and the age and level of professional education of the owners may also have an effect on standards of husbandry. The results show that the owners for whom FM represent a source of income more frequently keep their horses in standing stalls, but give them more time to exercise at liberty than the horses belonging to amateur breeders. Younger and better educated breeders are more likely to house their animals in groups.
Address Haras national suisse, Avenches
Corporate Author Thesis
Publisher Place of Publication Editor
Language French Summary Language Original Title L'influence de la structure socio-economique des exploitations d'elevage de chevaux de race franches-montagnes sur les conditions de detention
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0036-7281 ISBN Medium
Area Expedition Conference
Notes PMID:16703759 Approved no
Call Number Serial 1873
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