Records |
Author |
Menges, R.W.; Furcolow, M.L.; Selby, L.A.; Habermann, R.T.; Smith, C.D. |
Title |
Ecologic studies of histoplasmosis |
Type |
Journal Article |
Year |
1967 |
Publication |
American Journal of Epidemiology |
Abbreviated Journal |
Am J Epidemiol |
Volume |
85 |
Issue |
1 |
Pages |
108-119 |
Keywords |
Adolescent; Adult; Animals; Antibodies/*analysis; Carnivora; Cats; Cattle; Child; Child, Preschool; Dogs; Ecology; Female; Fluorescent Antibody Technique; Histoplasma/isolation & purification; Histoplasmin; Histoplasmosis/*epidemiology/*immunology; Horses; Humans; Infant; Infant, Newborn; Kansas; Male; Marsupialia; Mice; Middle Aged; Missouri; Rabbits; Skin Tests; *Soil Microbiology; Swine |
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ISSN |
0002-9262 |
ISBN |
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Conference |
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Notes |
PMID:5334640 |
Approved |
no |
Call Number |
Equine Behaviour @ team @ |
Serial |
2747 |
Permanent link to this record |
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Author |
[No authors listed] |
Title |
African horse sickness--a serious disease |
Type |
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Year |
2006 |
Publication |
Australian Veterinary Journal |
Abbreviated Journal |
Aust Vet J |
Volume |
84 |
Issue |
5 |
Pages |
N24-5 |
Keywords |
*African Horse Sickness/epidemiology/pathology/prevention & control/transmission; African horse sickness virus/pathogenicity; Animals; Australia/epidemiology; Disease Outbreaks/prevention & control/veterinary; *Equidae; Horses; Vaccination/veterinary |
Abstract |
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English |
Summary Language |
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Series Editor |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0005-0423 |
ISBN |
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Medium |
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Conference |
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Notes |
PMID:16739521 |
Approved |
no |
Call Number |
Equine Behaviour @ team @ |
Serial |
2356 |
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Author |
Gulotta, M.; Rogatsky, E.; Callender, R.H.; Dyer, R.B. |
Title |
Primary folding dynamics of sperm whale apomyoglobin: core formation |
Type |
Journal Article |
Year |
2003 |
Publication |
Biophysical Journal |
Abbreviated Journal |
Biophys J |
Volume |
84 |
Issue |
3 |
Pages |
1909-1918 |
Keywords |
Animals; Apoproteins/*chemistry; Crystallography/*methods; Horses; Myocardium/chemistry; Myoglobin/*chemistry; Protein Conformation; *Protein Folding; Species Specificity; Structure-Activity Relationship; Temperature; Whales |
Abstract |
The structure, thermodynamics, and kinetics of heat-induced unfolding of sperm whale apomyoglobin core formation have been studied. The most rudimentary core is formed at pH(*) 3.0 and up to 60 mM NaCl. Steady state for ultraviolet circular dichroism and fluorescence melting studies indicate that the core in this acid-destabilized state consists of a heterogeneous composition of structures of approximately 26 residues, two-thirds of the number involved for horse heart apomyoglobin under these conditions. Fluorescence temperature-jump relaxation studies show that there is only one process involved in Trp burial. This occurs in 20 micro s for a 7 degrees jump to 52 degrees C, which is close to the limits placed by diffusion on folding reactions. However, infrared temperature jump studies monitoring native helix burial are biexponential with times of 5 micro s and 56 micro s for a similar temperature jump. Both fluorescence and infrared fast phases are energetically favorable but the slow infrared absorbance phase is highly temperature-dependent, indicating a substantial enthalpic barrier for this process. The kinetics are best understood by a multiple-pathway kinetics model. The rapid phases likely represent direct burial of one or both of the Trp residues and parts of the G- and H-helices. We attribute the slow phase to burial and subsequent rearrangement of a misformed core or to a collapse having a high energy barrier wherein both Trps are solvent-exposed. |
Address |
Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York 10461, USA. gulotta@aecom.yu.edu |
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English |
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Edition |
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ISSN |
0006-3495 |
ISBN |
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Conference |
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Notes |
PMID:12609893 |
Approved |
no |
Call Number |
Equine Behaviour @ team @ |
Serial |
3783 |
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Author |
Ordakowski-Burk, A.L.; Quinn, R.W.; Shellem, T.A.; Vough, L.R. |
Title |
Voluntary intake and digestibility of reed canarygrass and timothy hay fed to horses |
Type |
Journal Article |
Year |
2006 |
Publication |
Journal of Animal Science |
Abbreviated Journal |
J. Anim Sci. |
Volume |
84 |
Issue |
11 |
Pages |
3104-3109 |
Keywords |
Animal Feed/*analysis; Animal Nutrition Physiology; Animals; Diet/*veterinary; Digestion/*physiology; Feeding Behavior/*physiology; Horses/*physiology; Male; Poaceae/*metabolism |
Abstract |
Thousands of hectares of timothy (Phleum pretense L.) grown in the Mid-Atlantic region are infected by cereal rust mite (Abacarus hysterix) that causes discoloration and curling of leaves, decreased nutritional quality, and substantial decreases in yield. A decline in production of timothy hay can lower income for hay producers and cause horse owners to search for alternative hays. Low alkaloid reed canarygrass (Phalaris arundinacea L.) hay has potential as an alternative to timothy hay because it grows well in the Mid-Atlantic region, is believed to have a similar nutrient quality to timothy, and is not as susceptible to cereal rust mite. Eleven mature, stalled Thoroughbred geldings (549 +/- 12.1 kg) that were exercised daily were used to compare voluntary DMI and apparent nutrient DM digestibility of timothy and low-alkaloid Chiefton variety reed canarygrass hay. Horses were paired by age and BW and randomly assigned to timothy or reed canarygrass hay during a 14-d period to measure voluntary DMI followed by a 4-d period to measure apparent DM digestibility. Both hays met the minimum requirements for DE, CP, Ca, P, K, Fe, and Mn, but they did not meet the minimum requirements for Cu, Zn, and Na for horses at maintenance and averaging 550 kg of BW. Timothy hay seemed to have a lower CP concentration (14.4%) compared with reed canarygrass hay (17.1%) and a more desirable Ca:P ratio at 1.6:1 compared with 0.8:1 for reed canarygrass hay. Horses fed timothy consumed more hay (P <0.001) during the voluntary DMI period compared with horses fed reed canarygrass. Greater voluntary DMI of timothy occurred on d 1, 3, and 5 (P <0.05), but DMI was similar for other days. Apparent DM digestibility was greater in horses fed timothy hay by 9.6% compared with horses fed reed canarygrass hay (P <0.05). Horses fed timothy had greater DM digestibility of ADF (P = 0.001), NDF (P = 0.001), sugar (P = 0.05), and Ca (P = 0.001) but lower apparent DM digestibility of CP (P = 0.012) and crude fat (P = 0.004). Timothy hay was superior in voluntary DMI and apparent DM digestibility compared with low-alkaloid reed canarygrass hay fed to horses. |
Address |
Department of Animal and Avian Sciences, University of Maryland, College Park 20742, USA. amyburk@umd.edu |
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English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
1525-3163 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
PMID:17032805 |
Approved |
no |
Call Number |
Equine Behaviour @ team @ |
Serial |
4236 |
Permanent link to this record |
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Author |
Davies, H.M.S. |
Title |
The timing and distribution of strains around the surface of the midshaft of the third metacarpal bone during treadmill exercise in one Thoroughbred racehorse |
Type |
Journal Article |
Year |
2005 |
Publication |
Australian Veterinary Journal |
Abbreviated Journal |
Aust Vet J |
Volume |
83 |
Issue |
3 |
Pages |
157-162 |
Keywords |
Animals; Exercise Test/veterinary; Female; Gait/*physiology; Horses/*physiology; Metacarpus/*physiology; Motor Activity/physiology; Physical Conditioning, Animal/*physiology; Stress, Mechanical; Weight-Bearing/physiology |
Abstract |
OBJECTIVE: To confirm that the midshaft dorsal cortex of the third metacarpal bone experienced higher compressive strains during fast exercise than the medial or lateral cortices, and that the strain peak occurred earlier in the hoof-down phase of the stride on the dorsal cortex than the medial or lateral cortices. DESIGN: Observations of a single horse. PROCEDURE: Strains were collected from a single, sound, 3-year-old Thoroughbred mare during treadmill exercise from rosette strain gauges implanted onto the medial, lateral and dorsal surfaces of the midshaft of the right cannon bone, simultaneously with data from a hoof switch that showed when the hoof was in the stance phase. RESULTS: Peak compressive strains on the dorsal surface of the third metacarpal bone were proportional to exercise speed and occurred at about 30% of stance. Peak compressive strains on the medial surface of the non-lead limb reached a maximum at a speed around 10 m/s and occurred at mid-stance. Peak compressive strains on the lateral surface varied in timing and size between strides at all exercise speeds, but remained less than -2000 microstrains. CONCLUSIONS: The timing of peak compressive strains on the dorsal cortex suggests a relationship to deceleration of the limb following hoof impact, so the main determinants of their size would be exercise speed and turning (as shown in previous experiments). This experiment confirms data from other laboratories that were published but not discussed, that peak compressive strains on the medial surface occur at mid-stance. This suggests that they are related to the support of body weight. The strains on the lateral cortex occurred at variable times so may be associated with the maintenance of balance as well as the support of body weight. Understanding the loading of the third metacarpal bone will help to determine causes of damage to it and ways in which the bone might be conditioned to prevent such damage. |
Address |
Department of Veterinary Science, University of Melbourne, Parkville, Victoria 3010. h.davies@unimelb.edu.au |
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English |
Summary Language |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0005-0423 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
PMID:15825628 |
Approved |
no |
Call Number |
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Serial |
1891 |
Permanent link to this record |
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Author |
Pearce, G.P.; May-Davis, S.; Greaves, D. |
Title |
Femoral asymmetry in the Thoroughbred racehorse |
Type |
Journal Article |
Year |
2005 |
Publication |
Australian Veterinary Journal |
Abbreviated Journal |
Aust Vet J |
Volume |
83 |
Issue |
6 |
Pages |
367-370 |
Keywords |
Animals; Cumulative Trauma Disorders/pathology/*veterinary; Femur/*pathology; Horse Diseases/*pathology/physiopathology; Horses; Locomotion; Physical Conditioning, Animal/*physiology |
Abstract |
OBJECTIVE: To investigate the occurrence of geometrical asymmetries in the macro-architecture of left and right femurs from Thoroughbred racehorses previously used in competitive training and racing in New South Wales, Australia. METHODS: Detailed postmortem measurements were made of 37 characteristics of left and right femurs from eleven Thoroughbred racehorses euthanased for reasons unrelated to the study. Measurements focused on articulating surfaces and sites of attachment of muscles and ligaments known to be associated with hindlimb locomotion. RESULTS: Five measurements were significantly larger in left compared to right femurs (P < 0.05). The regions showing significant differences between left and right limbs were proximal cranial and overhead medio-lateral widths, greater trochanter depth, depth of the fovea in the femoral head and distal inter-epicondylar width. CONCLUSION: The left-right differences in femoral morphology were associated with sites of muscle and ligament attachment known to be involved with hindlimb function in negotiating turns. These differences may be the result of selection pressure for racing performance on curved race tracks and/or adaptations related to asymmetrical loading of the outside hindlimb associated with repeated negotiation of turns on such tracks. |
Address |
Faculty of Rural Management, University of Sydney, Leeds Parade, Orange, New South Wales 2800. gpp28@cam.ac.uk |
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English |
Summary Language |
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Original Title |
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Series Editor |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0005-0423 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
PMID:15986917 |
Approved |
no |
Call Number |
Equine Behaviour @ team @ |
Serial |
4036 |
Permanent link to this record |
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Author |
Guo, G.L.; Moffit, J.S.; Nicol, C.J.; Ward, J.M.; Aleksunes, L.A.; Slitt, A.L.; Kliewer, S.A.; Manautou, J.E.; Gonzalez, F.J. |
Title |
Enhanced acetaminophen toxicity by activation of the pregnane X receptor |
Type |
Journal Article |
Year |
2004 |
Publication |
Toxicological sciences : an official journal of the Society of Toxicology |
Abbreviated Journal |
Toxicol Sci |
Volume |
82 |
Issue |
2 |
Pages |
374-380 |
Keywords |
Acetaminophen/pharmacokinetics/*toxicity; Analgesics, Non-Narcotic/pharmacokinetics/*toxicity; Animals; Aryl Hydrocarbon Hydroxylases/biosynthesis; Biotransformation; Blotting, Northern; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP3A; Membrane Proteins; Mice; Mice, Knockout; Oxidoreductases, N-Demethylating/biosynthesis; Pregnenolone Carbonitrile/pharmacology; Receptors, Cytoplasmic and Nuclear/*drug effects; Receptors, Steroid/*drug effects; Sulfhydryl Compounds/metabolism |
Abstract |
The pregnane X receptor (PXR) is a ligand-activated transcription factor and member of the nuclear receptor superfamily. Activation of PXR represents an important mechanism for the induction of cytochrome P450 3A (CYP3A) enzymes that can convert acetaminophen (APAP) to its toxic intermediate metabolite, N-acetyl-p-benzoquinone imine (NAPQI). Therefore, it was hypothesized that activation of PXR plays a major role in APAP-induced hepatotoxicity. Pretreatment with the PXR activator, pregnenolone 16alpha-carbonitrile (PCN), markedly enhanced APAP-induced hepatic injury, as revealed by increased serum ALT levels and hepatic centrilobular necrosis, in wild-type but not in PXR-null mice. Further analysis showed that following PCN treatment, PXR-null mice had lower CYP3A11 expression, decreased NAPQI formation, and increased maintenance of hepatic glutathione content compared to wild-type mice. Thus, these results suggest that PXR plays a critical role in APAP-induced hepatic toxicity, probably by inducing CYP3A11 expression and hence increasing bioactivation. |
Address |
Laboratory of Metabolism, CCR, NCI, NIH, Bethesda, Maryland 20892, USA |
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English |
Summary Language |
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Original Title |
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Series Editor |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
1096-6080 |
ISBN |
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Medium |
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Area |
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Conference |
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Notes |
PMID:15456926 |
Approved |
no |
Call Number |
refbase @ user @ |
Serial |
71 |
Permanent link to this record |
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Author |
Lazareva, O.F.; Smirnova, A.A.; Bagozkaja, M.S.; Zorina, Z.A.; Rayevsky, V.V.; Wasserman, E.A. |
Title |
Transitive responding in hooded crows requires linearly ordered stimuli |
Type |
Journal Article |
Year |
2004 |
Publication |
Journal of the experimental analysis of behavior |
Abbreviated Journal |
J Exp Anal Behav |
Volume |
82 |
Issue |
1 |
Pages |
1-19 |
Keywords |
Animals; *Association; Cognition/physiology; Crows; Discrimination (Psychology); *Discrimination Learning; Feedback; Reinforcement (Psychology); Visual Perception/physiology |
Abstract |
Eight crows were taught to discriminate overlapping pairs of visual stimuli (A+ B-, B+ C-, C+ D-, and D+ E-). For 4 birds, the stimuli were colored cards with a circle of the same color on the reverse side whose diameter decreased from A to E (ordered feedback group). These circles were made available for comparison to potentially help the crows order the stimuli along a physical dimension. For the other 4 birds, the circles corresponding to the colored cards had the same diameter (constant feedback group). In later testing, a novel choice pair (BD) was presented. Reinforcement history involving stimuli B and D was controlled so that the reinforcement/nonreinforcement ratios for the latter would be greater than for the former. If, during the BD test, the crows chose between stimuli according to these reinforcement/nonreinforcement ratios, then they should prefer D; if they chose according to the diameter of the feedback stimuli, then they should prefer B. In the ordered feedback group, the crows strongly preferred B over D; in the constant feedback group, the crows' choice did not differ significantly from chance. These results, plus simulations using associative models, suggest that the orderability of the postchoice feedback stimuli is important for crows' transitive responding. |
Address |
Institute of Higher Nervous Activity, Moscow State University. olga-lazareva@uiowa.edu |
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English |
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Edition |
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ISSN |
0022-5002 |
ISBN |
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Medium |
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Area |
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Conference |
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Notes |
PMID:15484868 |
Approved |
no |
Call Number |
refbase @ user @ |
Serial |
612 |
Permanent link to this record |
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Author |
Hirsch, B.T. |
Title |
Costs and benefits of within-group spatial position: a feeding competition model |
Type |
Journal Article |
Year |
2007 |
Publication |
The Quarterly review of biology |
Abbreviated Journal |
Q Rev Biol |
Volume |
82 |
Issue |
1 |
Pages |
9-27 |
Keywords |
Animals; Competitive Behavior/*physiology; Dominance-Subordination; Feeding Behavior/*physiology/*psychology; Population Dynamics; Predatory Behavior/*physiology |
Abstract |
An animal's within-group spatial position has several important fitness consequences. Risk of predation, time spent engaging in antipredatory behavior and feeding competition can all vary with respect to spatial position. Previous research has found evidence that feeding rates are higher at the group edge in many species, but these studies have not represented the entire breadth of dietary diversity and ecological situations faced by many animals. In particular the presence of concentrated, defendable food patches can lead to increased feeding rates by dominants in the center of the group that are able to monopolize or defend these areas. To fully understand the tradeoffs of within-group spatial position in relation to a variety of factors, it is important to be able to predict where individuals should preferably position themselves in relation to feeding rates and food competition. A qualitative model is presented here to predict how food depletion time, abundance of food patches within a group, and the presence of prior knowledge of feeding sites affect the payoffs of different within-group spatial positions for dominant and subordinate animals. In general, when feeding on small abundant food items, individuals at the front edge of the group should have higher foraging success. When feeding on slowly depleted, rare food items, dominants will often have the highest feeding rates in the center of the group. Between these two extreme points of a continuum, an individual's optimal spatial position is predicted to be influenced by an additional combination of factors, such as group size, group spread, satiation rates, and the presence of producer-scrounger tactics. |
Address |
Department of Anthropology, Stony Brook University Stony Brook, New York 11794, USA. BTHIRSCH@IC.SUNYSB.EDU |
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English |
Summary Language |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0033-5770 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
PMID:17354992 |
Approved |
no |
Call Number |
refbase @ user @ |
Serial |
803 |
Permanent link to this record |
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Author |
Devienne, M.F.; Guezennec, C.Y. |
Title |
Energy expenditure of horse riding |
Type |
Journal Article |
Year |
2000 |
Publication |
European Journal of Applied Physiology |
Abbreviated Journal |
Eur J Appl Physiol |
Volume |
82 |
Issue |
5-6 |
Pages |
499-503 |
Keywords |
Adult; Animals; Energy Metabolism/*physiology; Exercise/*physiology; Exercise Test; Female; Hemodynamic Processes/physiology; Horses; Humans; Male; Oxygen Consumption/physiology; Respiratory Mechanics/physiology |
Abstract |
Oxygen consumption (VO2), ventilation (VE) and heart rate (HR) were studied in five recreational riders with a portable oxygen analyser (K2 Cosmed, Rome) telemetric system, during two different experimental riding sessions. The first one was a dressage session in which the rider successively rode four different horses at a walk, trot and canter. The second one was a jumping training session. Each rider rode two horses, one known and one unknown. The physiological parameters were measured during warm up at a canter in suspension and when jumping an isolated obstacle at a trot and canter. This session was concluded by a jumping course with 12 obstacles. The data show a progressive increase in VO2 during the dressage session from a mean value of 0.70 (0.18) l x min(-1) [mean (SD)] at a walk, to 1.47 (0.28) l x min(-1) at a trot, and 1.9 (0.3) l x min(-1) at a canter. During the jumping session, rider VO2 was 2 (0.33) l x min(-1) with a mean HR of 155 beats x min(-1) during canter in suspension, obstacle trot and obstacle canter. The jumping course significantly enhanced VO2 and HR up to mean values of 2.40 (0.35) l x min(-1) and 176 beats x min(-1), respectively. The comparison among horses and riders during the dressage session shows differences in energy expenditure according to the horse for the same rider and between riders. During the jumping session, there was no statistical difference between riders riding known and unknown horses. In conclusion these data confirm that riding induces a significant increase in energy expenditure. During jumping, a mean value of 75% VO2max was reached. Therefore, a good aerobic capacity seems to be a factor determining riding performance in competitions. Regular riding practice and additional physical training are recommended to enhance the physical fitness of competitive riders. |
Address |
Universite Paris XII-STAPS-61, Creteil, France. Mfdevienne@aol.com |
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English |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
1439-6319 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
PMID:10985607 |
Approved |
no |
Call Number |
Equine Behaviour @ team @ |
Serial |
3731 |
Permanent link to this record |