| Records |
| Author |
Harman, F.S.; Nicol, C.J.; Marin, H.E.; Ward, J.M.; Gonzalez, F.J.; Peters, J.M. |
| Title |
Peroxisome proliferator-activated receptor-delta attenuates colon carcinogenesis |
Type |
Journal Article |
| Year |
2004 |
Publication |
Nature medicine |
Abbreviated Journal |
Nat Med |
Volume  |
10 |
Issue |
5 |
Pages |
481-483 |
| Keywords |
Animals; Azoxymethane/toxicity; Colonic Neoplasms/etiology/genetics/*prevention & control; Colonic Polyps/etiology/genetics/pathology/prevention & control; Disease Models, Animal; Mice; Mice, Knockout; Mice, Mutant Strains; Phenotype; Receptors, Cytoplasmic and Nuclear/deficiency/genetics/*physiology; Transcription Factors/deficiency/genetics/*physiology |
| Abstract |
Peroxisome proliferator-activated receptor-delta (PPAR-delta; also known as PPAR-beta) is expressed at high levels in colon tumors, but its contribution to colon cancer is unclear. We examined the role of PPAR-delta in colon carcinogenesis using PPAR-delta-deficient (Ppard(-/-)) mice. In both the Min mutant and chemically induced mouse models, colon polyp formation was significantly greater in mice nullizygous for PPAR-delta. In contrast to previous reports suggesting that activation of PPAR-delta potentiates colon polyp formation, here we show that PPAR-delta attenuates colon carcinogenesis. |
| Address |
Department of Veterinary Science and The Center for Molecular Toxicology and Carcinogenesis, The Pennsylvania State University, University Park, Pennsylvania 16802, USA. jmp21@psu.edu |
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English |
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| ISSN |
1078-8956 |
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| Notes |
PMID:15048110 |
Approved |
no |
| Call Number |
refbase @ user @ |
Serial |
77 |
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| Author |
Bouman, I. |
| Title |
The reintroduction of Przewalski horses in the Hustain Nuruu Mountain Forest Steppe Reserve in Mongolia |
Type |
Journal Article |
| Year |
1998 |
Publication |
Mededelingen: Netherlands Commission for International Nature Protection |
Abbreviated Journal |
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| Volume |
32 |
Issue |
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no |
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Equine Behaviour @ team @ |
Serial |
2241 |
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| Author |
Pocock Rj, |
| Title |
The coloration of the Quaggas |
Type |
Journal Article |
| Year |
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Publication |
Nature |
Abbreviated Journal |
Nature |
| Volume |
68 |
Issue |
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Pages |
356-357 |
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| Notes |
from Professor Hans Klingels Equine Reference List |
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no |
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Serial |
1480 |
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| Author |
Buttiker, W. |
| Title |
[Preliminary report on eye-frequenting butterflies in the Ivory Coast] |
Type |
Journal Article |
| Year |
1973 |
Publication |
Revue Suisse de Zoologie; Annales de la Societe Zoologique Suisse et du Museum d'Histoire Naturelle de Geneve |
Abbreviated Journal |
Rev Suisse Zool |
| Volume |
80 |
Issue |
1 |
Pages |
1-43 |
| Keywords |
Animals; Behavior, Animal; Cattle; Cote d'Ivoire; Ecology; Ectoparasitic Infestations/*veterinary; *Eye; Horses; *Insects; *Parasites; Sheep |
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German |
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Original Title |
Vorlaufige Beobachtungen an augenbesuchenden Schmetterlingen in der Elfenbeinkuste |
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0035-418X |
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PMID:4354354 |
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no |
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Equine Behaviour @ team @ |
Serial |
2716 |
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| Author |
Henry, S.; Fureix, C.; Rowberry, R.; Bateson, M.; Hausberger, M. |
| Title |
Do horses with poor welfare show 'pessimistic' cognitive biases? |
Type |
Journal Article |
| Year |
2017 |
Publication |
The Science of Nature |
Abbreviated Journal |
Sci. Nat. |
| Volume |
104 |
Issue |
1 |
Pages |
8 |
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| Abstract |
This field study tested the hypothesis that domestic horses living under putatively challenging-to-welfare conditions (for example involving social, spatial, feeding constraints) would present signs of poor welfare and co-occurring pessimistic judgement biases. Our subjects were 34 horses who had been housed for over 3 years in either restricted riding school situations (e.g. kept in single boxes, with limited roughage, ridden by inexperienced riders; N = 25) or under more naturalistic conditions (e.g. access to free-range, kept in stable social groups, leisure riding; N = 9). The horses' welfare was assessed by recording health-related, behavioural and postural indicators. Additionally, after learning a location task to discriminate a bucket containing either edible food ('positive' location) or unpalatable food ('negative' location), the horses were presented with a bucket located near the positive position, near the negative position and halfway between the positive and negative positions to assess their judgement biases. The riding school horses displayed the highest levels of behavioural and health-related problems and a pessimistic judgment bias, whereas the horses living under more naturalistic conditions displayed indications of good welfare and an optimistic bias. Moreover, pessimistic bias data strongly correlated with poor welfare data. This suggests that a lowered mood impacts a non-human species' perception of its environment and highlights cognitive biases as an appropriate tool to assess the impact of chronic living conditions on horse welfare. |
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1432-1904 |
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no |
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Equine Behaviour @ team @ Henry2017 |
Serial |
6665 |
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| Author |
Alexander, F.; Chowdhury, A.K. |
| Title |
Enzymes in the ileal juice of the horse |
Type |
Journal Article |
| Year |
1958 |
Publication |
Nature |
Abbreviated Journal |
Nature |
| Volume |
181 |
Issue |
4603 |
Pages |
190 |
| Keywords |
*Enzymes; *Horses; Ileum/*metabolism; *Enzymes; *Horses; *ILEUM/metabolism |
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English |
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| ISSN |
0028-0836 |
ISBN |
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| Notes |
PMID:13504127 |
Approved |
no |
| Call Number |
refbase @ user @ |
Serial |
121 |
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| Author |
Goodall J |
| Title |
Tool-using and aimed throwing in a community of free-living chimpanzees |
Type |
Journal Article |
| Year |
1964 |
Publication |
Nature |
Abbreviated Journal |
Nature |
| Volume |
201 |
Issue |
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Pages |
1264 |
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Approved |
no |
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Equine Behaviour @ team @ |
Serial |
3000 |
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| Author |
Gilbert, B.K.; Hailman, J.P. |
| Title |
Uncertainty of leadership-rank in fallow deer |
Type |
Journal Article |
| Year |
1966 |
Publication |
Nature |
Abbreviated Journal |
Nature |
| Volume |
209 |
Issue |
5027 |
Pages |
1041-1042 |
| Keywords |
Animals; Artiodactyla; *Behavior, Animal; Female; *Leadership; Pregnancy |
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English |
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0028-0836 |
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| Notes |
PMID:5927524 |
Approved |
no |
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Serial |
2057 |
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| Author |
Hamilton, W.D. |
| Title |
Selfish and Spiteful Behaviour in an Evolutionary Model |
Type |
Journal Article |
| Year |
1970 |
Publication |
Nature |
Abbreviated Journal |
Nature |
| Volume |
228 |
Issue |
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Pages |
1218-1220 |
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| Notes |
10.1038/2281218a0 |
Approved |
no |
| Call Number |
Equine Behaviour @ team @ |
Serial |
4853 |
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| Author |
Maynard Smith, J.; Price, G.R. |
| Title |
The Logic of Animal Conflict |
Type |
Journal Article |
| Year |
1973 |
Publication |
Nature |
Abbreviated Journal |
Nature |
| Volume |
246 |
Issue |
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Pages |
15-18 |
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| Notes |
10.1038/246015a0 |
Approved |
no |
| Call Number |
Equine Behaviour @ team @ |
Serial |
4844 |
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