Records |
Author |
Stull, C.L.; Spier, S.J.; Aldridge, B.M.; Blanchard, M.; Stott, J.L. |
Title |
Immunological response to long-term transport stress in mature horses and effects of adaptogenic dietary supplementation as an immunomodulator |
Type |
Journal Article |
Year |
2004 |
Publication |
Equine Veterinary Journal |
Abbreviated Journal |
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Volume |
36 |
Issue |
7 |
Pages |
583-589 |
Keywords |
horse; transportation; Cd+; lymphocytes; stress; cortisol; adaptogens |
Abstract |
Reasons for performing study: Little information exists on the immunological effects of transport or the use of supplements to minimise transport stress. Objectives: To establish baseline ranges and evaluate immunophenotypic and functional changes associated with transport and a nutritional ‘adaptogen’ supplement. Methods: Horses received either supplement (n = 10) or placebos (n = 9) during the 30 day study. After 28 days in stalls, 12 horses (6 supplement; 6 placebo) were transported for 24 h, then unloaded and recovered. Venous blood samples were collected on Days 1, 14 and 28 to establish baselines, and on Days 28, 29 and 30 to examine changes during transport and recovery. Results: Transport prompted elevations (P<0.05) in cortisol concentration, neutrophil count and white blood cell counts, while lymphocyte subpopulation counts (CD3+, CD4+, CD8+, CD21+) decreased (P<0.05). Normal phenotypic lymphocyte profiles returned within 24 h of recovery. Supplement effects on immunophenotype (CD21+ and CD8+) were observed in stabled horses (P<0.05), but not in transported horses. Conclusions: These results provide insights into the immunological mechanisms associated with long-term transport. Potential relevance: The existence of a small window of immunological uncertainty follows long-term transportation, enhancing the potential risk of infectious disease in susceptible individuals. |
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Blackwell Publishing Ltd |
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ISSN |
2042-3306 |
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Call Number |
Equine Behaviour @ team @ |
Serial |
5845 |
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Author |
Ferguson, D.L.; Rosales-Ruiz, J. |
Title |
Loading the problem loader: the effects of target training and shaping on trailer-loading behavior of horses |
Type |
Journal Article |
Year |
2001 |
Publication |
Journal of Applied Behavior Analysis |
Abbreviated Journal |
J Appl Behav Anal |
Volume |
34 |
Issue |
4 |
Pages |
409-423 |
Keywords |
Animals; *Conditioning, Operant; *Escape Reaction; Female; Horses/*psychology; Reinforcement (Psychology); *Transportation |
Abstract |
The purpose of this study was to develop an effective method for trailer loading horses based on principles of positive reinforcement. Target training and shaping were used to teach trailer-loading behavior to 5 quarter horse mares in a natural setting. All 5 had been trailer loaded before through the use of aversive stimulation. Successive approximations to loading and inappropriate behaviors were the dependent variables. After training a horse to approach a target, the target was moved to various locations inside the trailer. Horses started training on the left side of a two-horse trailer. After a horse was loading on the left side, she was moved to the right side, then to loading half on the right and half on the left. A limited-hold procedure and the presence of a companion horse seemed to facilitate training for 1 horse. Inappropriate behaviors fell to zero immediately after target training, and all the horses successfully completed the shaping sequence. Finally, these effects were observed to generalize to novel conditions (a different trainer and a different trailer). |
Address |
University of North Texas, Denton 76203, USA |
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English |
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0021-8855 |
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PMID:11800182 |
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no |
Call Number |
refbase @ user @ |
Serial |
1915 |
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Author |
Marlin, D.J.; Schroter, R.C.; White, S.L.; Maykuth, P.; Matthesen, G.; Mills, P.C.; Waran, N.; Harris, P. |
Title |
Recovery from transport and acclimatisation of competition horses in a hot humid environment |
Type |
Journal Article |
Year |
2001 |
Publication |
Equine Veterinary Journal |
Abbreviated Journal |
Equine Vet J |
Volume |
33 |
Issue |
4 |
Pages |
371-379 |
Keywords |
Acclimatization/*physiology; Animals; Body Temperature; Body Weight; Breeding; Feeding Behavior; Female; Heart Rate; Heat; Heat Stroke/prevention & control/veterinary; Horse Diseases/prevention & control; Horses/*physiology; Humidity; Male; Respiration; Sports; *Transportation; Tropical Climate |
Abstract |
The aims of the present field-based study were to investigate changes in fit horses undergoing acclimatisation to a hot humid environment and to provide data on which to base recommendations for safe transport and acclimatisation. Six horses (age 7-12 years) were flown from Europe to Atlanta and underwent a 16 day period of acclimatisation. Exercise conditions during acclimatisation (wet bulb globe temperature index 27.6+/-0.0 [mean +/- s.e.]) were more thermally stressful compared with the European climate from which the horses had come (22.0+/-1.8, P<0.001). Following the flight, weight loss was 4.1+/-0.8% bodyweight and took around 7 days to recover. Water intake during the day was significantly increased (P<0.05) compared with night during acclimatisation. Daily mean exercise duration was 72+/-12 min and the majority of work was performed with a heart rate below 120 beats/min. Respiratory rate (fR) was increased (P<0.05) throughout acclimatisation compared with in Europe, but resting morning (AM) and evening (PM) rectal temperature (TREC), heart rate (fC) and plasma volume were unchanged. White blood cell (WBC) count was significantly increased at AM compared with in Europe on Days 4 and 10 of acclimatisation (P<0.01), but was not different by Day 16. In conclusion, horses exposed to hot humid environmental conditions without prior acclimatisation are able to accommodate these stresses and, with appropriate management, remain fit and clinically healthy, without significant risk of heat illness or heat-related disorders, provided they are allowed sufficient time to recover from transport, acclimatisation is undertaken gradually and they are monitored appropriately. |
Address |
Centre for Equine Studies, Animal Health Trust, Newmarket, Suffolk, UK |
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English |
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Edition |
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ISSN |
0425-1644 |
ISBN |
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Notes |
PMID:11469770 |
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no |
Call Number |
refbase @ user @ |
Serial |
1917 |
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Author |
Fazio, E.; Ferlazzo, A. |
Title |
Evaluation of Stress During Transport |
Type |
Journal Article |
Year |
2003 |
Publication |
Veterinary Research Communications |
Abbreviated Journal |
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Volume |
27 |
Issue |
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Pages |
519-524 |
Keywords |
hormones – physiological variables – stress – transport procedures |
Abstract |
Domestic animals are transported for a variety of reasons including breeding, biomedical purposes, slaughter and, in the case of sporting horses, for competitions, pleasure activities or ceremonial proceedings. Studies to determine the amount of stress on farm animals during transport often have highly variable results and are difficult to interpret. The reaction of animals to stressors depends on the duration and intensity of the stressors, the animal's previous experience, its physiological status and the immediate environmental restraints. Behavioural, haematological, haematochemical, physiological and neuro-hormonal (ß-endorphin, ACTH, cortisol, iodothyronines) variables are discussed on the basis of handling, loading and transport procedures of animals. |
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Call Number |
Equine Behaviour @ team @ |
Serial |
4391 |
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Author |
Atock, M.A.; Williams, R.B. |
Title |
Welfare of competition horses |
Type |
Journal Article |
Year |
1994 |
Publication |
Revue Scientifique et Technique (International Office of Epizootics) |
Abbreviated Journal |
Rev Sci Tech |
Volume |
13 |
Issue |
1 |
Pages |
217-232 |
Keywords |
*Animal Welfare; Animals; Doping in Sports; Ethics; Heat; Horses/*physiology; Housing, Animal/standards; Humidity; International Cooperation; Sports/*standards; Transportation/standards; Veterinary Medicine |
Abstract |
In the large majority of cases and circumstances, horses benefit from their association with man. However, abuse of horses can occur, due to neglect or through the pressures of competition. The welfare of all animals, including competition horses, has become increasingly topical over the past ten years. Equestrian sport is coming under closer public scrutiny due to reports of apparent abuse. The bodies responsible for regulating these sports strenuously endeavour to protect the welfare of horses which compete under their rules and regulations. The Federation Equestre Internationale (FEI: International Equestrian Federation) is the sole authority for all international events in dressage, show-jumping, three-day event, driving, endurance riding and vaulting. The FEI rules illustrate the ways in which the welfare of competing horses is safeguarded. |
Address |
Federation Equestre Internationale, Lausanne, Switzerland |
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English |
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ISSN |
0253-1933 |
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Notes |
PMID:8173097 |
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no |
Call Number |
Equine Behaviour @ team @ |
Serial |
3747 |
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Author |
Czerlinski, G.H.; Erickson, J.O.; Theorell, H. |
Title |
Chemical relaxation studies on the horse liver alcohol dehydrogenase system |
Type |
Journal Article |
Year |
1979 |
Publication |
Physiological Chemistry and Physics |
Abbreviated Journal |
Physiol Chem Phys |
Volume |
11 |
Issue |
6 |
Pages |
537-569 |
Keywords |
Alcohol Oxidoreductases/*metabolism; Animals; Buffers; Electron Transport; Ethanol/metabolism; Horses; Hydrogen-Ion Concentration; Liver/*enzymology; Mathematics; NAD/metabolism; Oscillometry; Osmolar Concentration; Temperature; Time Factors |
Abstract |
Chemical relaxation studies on the system horse liver alcohol dehydrogenase, nicotinamide adenine dinucleotide, and ethanol were conducted observing fluorescence changes between 400 and 500 nm. Temperature-jump experiments were performed at pH 6.5, 7.0, 8.0, and 9.0; concentration-jump experiments at pH 9.0. The reciprocal of the slowest relaxation time was found to be linearly dependent upon the enzyme concentration for relatively low enzyme concentrations, as predicted earlier. Use of the wide pH-range necessitated expression of the four apparent dissociation constants of the catalytic reaction cycle in terms of pH-independent constants. The system was described in terms of only one (or two) catalysis-linked protons not associated with the electron transfer. Protonic steps in a buffered system are in rapid equilibrium, too fast to be measured with the equipment available. Assuming only two of the four bimolecular reaction steps in the four-step cycle are fast compared to the remaining two, six cases may be considered with six expressions for the reciprocal of the slowest relaxation time. Comparison with the experimental data revealed that the bimolecular reaction steps governing the slowest relaxation time change with pH. Above the effective time resolution of the temperature-lump instrument with fluorescence detection (0.1 msec) only one other relaxation time was detectable and only at pH 9. This relaxation time, found to be independent of the concentration of all reactants within experimental error (r = 10 +/- 5 msec), is most likely due to an interconversion among ternary complexes. |
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English |
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ISSN |
0031-9325 |
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Notes |
PMID:44918 |
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no |
Call Number |
Equine Behaviour @ team @ |
Serial |
3813 |
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Author |
Wilson, M.T.; Silvestrini, M.C.; Morpurgo, L.; Brunori, M. |
Title |
Electron transfer kinetics between Rhus vernicifera stellacyanin and cytochrome c (horse heart cytochrome c and Pseudomonas cytochrome c551) |
Type |
Journal Article |
Year |
1979 |
Publication |
Journal of Inorganic Biochemistry |
Abbreviated Journal |
J Inorg Biochem |
Volume |
11 |
Issue |
2 |
Pages |
95-100 |
Keywords |
Animals; Copper; Cytochrome c Group/*metabolism; Electron Transport; Kinetics; Metalloproteins/*metabolism; Plant Proteins/*metabolism; *Plants, Toxic; Pseudomonas aeruginosa/*metabolism; Toxicodendron/*metabolism |
Abstract |
The electron transfer reactions between Rhus vernicifera stellacyanin and either horse heart cytochrome c or Pseudomonas aeruginosa cytochrome c551 were investigated by rapid reaction techniques. The time course of electron transfer is monophasic under all conditions, and thus consistent with a simple formulation of the reaction. Both stopped-flow and temperature-jump experiments yield equilibrium constants in reasonable agreement with values calculated from the redox potentials. The differences in reaction rate between the two cytochromes and stellacyanin are discussed in terms of the Marcus theory. |
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English |
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Edition |
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ISSN |
0162-0134 |
ISBN |
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Notes |
PMID:228006 |
Approved |
no |
Call Number |
refbase @ user @ |
Serial |
3879 |
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Author |
Boray, J.C. |
Title |
Experimental fascioliasis in Australia |
Type |
Journal Article |
Year |
1969 |
Publication |
Advances in Parasitology |
Abbreviated Journal |
Adv Parasitol |
Volume |
7 |
Issue |
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Pages |
95-210 |
Keywords |
Adaptation, Biological; Adaptation, Physiological; Animal Nutrition Physiology; Animals; Animals, Laboratory; Australia; Cattle; *Cattle Diseases/pathology; Climate; *Disease Vectors; Ecology; Electron Transport; Estivation; Fasciola hepatica/enzymology/*growth & development/metabolism/physiology; Fascioliasis/epidemiology/immunology/*prevention & control/veterinary; Glycolysis; Guinea Pigs; Horses; Humans; Larva/growth & development/physiology; Marsupialia; Metamorphosis, Biological; Mice; New Guinea; New Zealand; Parasite Egg Count; Rats; Seasons; Sheep; *Sheep Diseases/pathology |
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English |
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ISSN |
0065-308X |
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PMID:4935272 |
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no |
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Equine Behaviour @ team @ |
Serial |
2744 |
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Author |
Shanahan, S. |
Title |
Trailer loading stress in horses: behavioral and physiological effects of nonaversive training (TTEAM) |
Type |
Journal Article |
Year |
2003 |
Publication |
Journal of Applied Animal Welfare Science : JAAWS |
Abbreviated Journal |
J Appl Anim Welf Sci |
Volume |
6 |
Issue |
4 |
Pages |
263-274 |
Keywords |
Animals; *Conditioning, Operant; *Escape Reaction; Female; Heart Rate; Horses/*psychology; Hydrocortisone/metabolism; Male; Saliva/metabolism; Stress/metabolism/prevention & control/*veterinary; *Transportation |
Abstract |
Resistance in the horse to trailer loading is a common source of stress and injury to horses and their handlers. The objective of this study was to determine whether nonaversive training based on the Tellington-Touch Equine Awareness Method (TTEAM; Tellington-Jones &Bruns, 1988) would decrease loading time and reduce stress during loading for horses with a history of reluctance to load. Ten horses described by their owners as “problem loaders” were subjected to pretraining and posttraining assessments of loading. Each assessment involved two 7-min loading attempts during which heart rate and saliva cortisol were measured. The training consisted of six 30-min sessions over a 2-week period during which the horse and owner participated in basic leading exercises with obstacles simulating aspects of trailering. Assessment showed heart rate and saliva cortisol increased significantly during loading as compared to baseline (p <.001 and p <.05, respectively). Reassessment after training showed a decrease in loading time (p <.02), reduced heart rate during loading (p <.002), and reduced saliva cortisol as compared to pretraining assessments. Seven “good loaders” also were subject to loading assessment for physiological comparison. Increases in heart rate during loading were significantly higher in the good loaders (p <.001). Nonaversive training simulating aspects of loading may effectively reduce loading time and stress during loading for horses with a history of resistance to trailer loading. |
Address |
shanahandvm@yahoo.ca |
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Edition |
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ISSN |
1088-8705 |
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PMID:14965781 |
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1903 |
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Author |
Houpt, K.A. |
Title |
Stable vices and trailer problems |
Type |
Journal Article |
Year |
1986 |
Publication |
The Veterinary clinics of North America. Equine practice |
Abbreviated Journal |
Vet Clin North Am Equine Pract |
Volume |
2 |
Issue |
3 |
Pages |
623-633 |
Keywords |
Aerophagy/veterinary; Aggression; Animals; *Animals, Domestic; *Behavior, Animal; Fear; Frustration; Habits; *Horses; Locomotion; Mastication; Social Environment; Transportation |
Abstract |
Stable vices include oral vices such as cribbing, wood chewing, and coprophagia, as well as stall walking, weaving, pawing, and stall kicking. Some of these behaviors are escape behaviors; others are forms of self-stimulation. Most can be eliminated by pasturing rather than stall confinement. Trailering problems include failure to load, scrambling in the moving trailer, struggling in the stationary trailer, and refusal to unload. Gradual habituation to entering the trailer, the presence of another horse, or a change in trailer type can be used to treat these problems. |
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0749-0739 |
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PMID:3492249 |
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no |
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refbase @ user @ |
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48 |
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