| Records |
| Author |
Petter-Puchner, A.H.; Froetscher, W.; Krametter-Froetscher, R.; Lorinson, D.; Redl, H.; van Griensven, M. |
| Title |
The long-term neurocompatibility of human fibrin sealant and equine collagen as biomatrices in experimental spinal cord injury |
Type |
Journal Article |
| Year |
2007 |
Publication |
Experimental and Toxicologic Pathology : Official Journal of the Gesellschaft fur Toxikologische Pathologie |
Abbreviated Journal |
Exp Toxicol Pathol |
| Volume |
58 |
Issue |
4 |
Pages |
237-245 |
| Keywords |
Animals; Axotomy; Biocompatible Materials/*therapeutic use; Collagen/*therapeutic use; Fibrin Tissue Adhesive/*therapeutic use; Horses; Humans; Immunohistochemistry; Male; Motor Activity/physiology; Nerve Regeneration/*physiology; Rats; Recovery of Function; Spinal Cord/pathology/physiology; Spinal Cord Injuries/pathology/*therapy; Thoracic Vertebrae |
| Abstract |
INTRODUCTION: While fibrin sealant (FS) and equine collagen (EC) have been used as scaffold materials in experimental spinal cord injury (SCI), questions concerning neurocompatibility still remain. In this study, we assessed potential adverse effects, as well as functional and histological impact of FS and EC in subtotal hemisection of the thoracic spinal cord (SC) in rats. METHODS: 124 male rats were randomly assigned to four main groups (n=31): Sham (SH), Lesion only (L), fibrin sealant (GFS) and equine collagen group (GEC). SH animals received laminectomy only; all other animals underwent subtotal lateral hemisection at T9. Treatment consisted of application of FS or EC into the lesion gap in GFS and GEC, which was left empty in L. GFS, GEC, L and SH were each further divided into 4 subgroups: One subgroup, consisting of 10 rats was subjected to behavioural and reflex testing before surgery and followed up on days 1,7, 14, 21, 28 post op and then sacrificed. Haemalaun or cresyl violet (CV) was used to identify neutrophils in parasagittal cord sections which were obtained on day 1 (n=7). Sections stained for quantification of microglia/macrophages using ED-1 on day 3 (n=7), day 7 (n=7) and day 28 (n=7 out of 10). Additionally, neural filament (NF) staining was chosen to detect axonal regeneration and the length of ingrowth into FS and EC, Luxol blue for myelination, Von Willebrand factor for vascularisation, and glial fibrillary acidic protein (GFAP) staining for detection of astrocytes in glial scars on day 28. RESULTS: No adverse effects were observed in the treatment groups. Compared to L, GFS and GEC performed significantly better in the Basso, Beattie, Bresnahan (BBB) score and hopping responses. Proprioceptive placing was markedly improved in FS and EC compared to L. Axonal regrowth was found in GFS and GEC--the regrowth in the GFS was accompanied by myelination and vascularisation. Glial scarring occurred in all groups. Discussion Both biomatrices improved functional recovery compared to L and no adverse effects were perceived. |
| Address |
Ludwig Boltzmann Institute of Experimental and Clinical Traumatology, Donaueschingenstrasse 13, 1200-Vienna, Austria |
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English |
Summary Language |
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Original Title |
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Series Title |
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Abbreviated Series Title |
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Series Issue |
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Edition |
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| ISSN |
0940-2993 |
ISBN |
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Medium |
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Expedition |
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Conference |
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| Notes |
PMID:17118635 |
Approved |
no |
| Call Number |
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Serial |
1852 |
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| Author |
Landsberg, G.; Araujo, J.A. |
| Title |
Behavior problems in geriatric pets |
Type |
Journal Article |
| Year |
2005 |
Publication |
The Veterinary Clinics of North America. Small Animal Practice |
Abbreviated Journal |
Vet Clin North Am Small Anim Pract |
| Volume |
35 |
Issue |
3 |
Pages |
675-698 |
| Keywords |
Aging/*pathology/physiology/*psychology; Animals; *Behavior, Animal; Cats/*physiology/psychology; Cognition/physiology; Diagnosis, Differential; Dogs/*physiology/psychology; Preventive Medicine |
| Abstract |
Aging pets often suffer a decline in cognitive function (eg, memory,learning, perception, awareness) likely associated with age-dependent brain alterations. Clinically, cognitive dysfunction may result in various behavioral signs, including disorientation; forgetting of previously learned behaviors, such as house training; alterations in the manner in which the pet interacts with people or other pets;onset of new fears and anxiety; decreased recognition of people, places, or pets; and other signs of deteriorating memory and learning ability. Many medical problems, including other forms of brain pathologic conditions, can contribute to these signs. The practitioner must first determine the cause of the behavioral signs and then determine an appropriate course of treatment, bearing in mind the constraints of the aging process. A diagnosis of cognitive dysfunction syndrome is made once other medical and behavioral causes are ruled out. |
| Address |
Doncaster Animal Clinic, 99 Henderson Avenue, Thornhill, Ontario L3T2K9, Canada. gmlandvm@aol.com |
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English |
Summary Language |
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Original Title |
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Series Title |
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Abbreviated Series Title |
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Series Issue |
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Edition |
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| ISSN |
0195-5616 |
ISBN |
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Medium |
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| Area |
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Expedition |
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Conference |
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| Notes |
PMID:15833565 |
Approved |
no |
| Call Number |
Equine Behaviour @ team @ |
Serial |
2855 |
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| Author |
O'Grady, S.E. |
| Title |
Basic farriery for the performance horse |
Type |
Journal Article |
| Year |
2008 |
Publication |
The Veterinary Clinics of North America. Equine Practice |
Abbreviated Journal |
Vet Clin North Am Equine Pract |
| Volume |
24 |
Issue |
1 |
Pages |
203-218 |
| Keywords |
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| Abstract |
Proper farriery promotes a healthy functional foot and biomechanical efficiency and prevents lameness. Because the equine veterinarian is responsible for the soundness of the horse, a working knowledge of farriery becomes essential. A thorough knowledge of traditional horseshoeing enables the veterinarian to interact with the farrier at the farrier's level; this ultimately enhances and promotes quality hoof care. This article focuses on fundamental farriery and recognizing subtle changes in hoof conformation that can be used to preserve the integrity of the hoof capsule, along with the structures enclosed within, and thus prevent lameness in the performance horse. |
| Address |
Northern Virginia Equine, 8170 Patrickswell Lane, Marshall, VA 20115, USA. sogrady@look.net |
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English |
Summary Language |
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Original Title |
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Abbreviated Series Title |
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Series Issue |
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Edition |
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| ISSN |
1558-4224 |
ISBN |
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Medium |
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| Area |
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Expedition |
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Conference |
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| Notes |
PMID:18314044 |
Approved |
no |
| Call Number |
Equine Behaviour @ team @ |
Serial |
4373 |
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| Author |
Weishaupt, M.A. |
| Title |
Adaptation strategies of horses with lameness |
Type |
Journal Article |
| Year |
2008 |
Publication |
The Veterinary Clinics of North America. Equine Practice |
Abbreviated Journal |
Vet Clin North Am Equine Pract |
| Volume |
24 |
Issue |
1 |
Pages |
79-100 |
| Keywords |
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| Abstract |
The skill to diagnose lameness in horses is paramount for every equine practitioner. Early recognition of locomotor deficiencies plays a central role in sports medicine management, preventing deterioration of the disease or catastrophic injuries. Horses use characteristic compensatory movements of specific body parts to decrease loading of the affected limb. This article describes the underlying changes in intra- and interlimb coordination and the resulting load redistribution between the limbs. This enables the practitioner to better understand the changes in movement associated with lameness. |
| Address |
Equine Department, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, CH-8057 Zurich, Switzerland. mweishaupt@vetclinics.uzh.ch |
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English |
Summary Language |
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Original Title |
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Series Title |
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Abbreviated Series Title |
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Series Issue |
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Edition |
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| ISSN |
1558-4224 |
ISBN |
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Medium |
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| Area |
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Expedition |
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Conference |
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| Notes |
PMID:18314037 |
Approved |
no |
| Call Number |
Equine Behaviour @ team @ |
Serial |
4372 |
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| Author |
Dargatz, D.A.; Traub-Dargatz, J.L. |
| Title |
Multidrug-resistant Salmonella and nosocomial infections |
Type |
Journal Article |
| Year |
2004 |
Publication |
The Veterinary Clinics of North America. Equine Practice |
Abbreviated Journal |
Vet Clin North Am Equine Pract |
| Volume |
20 |
Issue |
3 |
Pages |
587-600 |
| Keywords |
Animals; Anti-Bacterial Agents/*pharmacology; Cross Infection/prevention & control/*veterinary; Disease Outbreaks/prevention & control/veterinary; Drug Resistance, Bacterial; *Drug Resistance, Multiple, Bacterial; Horse Diseases/*drug therapy/transmission; Horses; Infection Control/methods; Microbial Sensitivity Tests/veterinary; Salmonella/*drug effects; Salmonella Infections, Animal/*drug therapy/transmission |
| Abstract |
Nosocomial infections are a serious threat to optimum patient care. In addition, nosocomial infections can have far-reaching consequences for the hospital personnel and the financial aspects of the hospital. Nosocomial infections with Salmonella spp have been described among hospitalized equine populations more frequently than any other agent. Salmonella spp associated with hospitalized equids often possess more antimicrobial resistance determinants than do Salmonella spp isolated from healthy horses in the general population. There is little evidence to suggest that resistant salmonellae are more virulent than nonresistant forms. MDR forms of Salmonella complicate the selection of appropriate antimicrobials when they are indicated, however. Furthermore, the use of some antimicrobials may apply selection pressure toward enhanced ability of MDR Salmonella to colonize equine patients. Further research should help to elucidate the risky uses of antimicrobials in the hospital setting and define the role of disinfectants and treatments such as NSAIDs in the ecology of MDR forms of nosocomial infections, including Salmonella. In the meantime, thoughtful selection of when and how to use antimicrobials in equine patients, together with deliberate selection of which antimicrobials to use based on monitoring data and other factors, such as safety and spectrum, is advised. |
| Address |
Animal and Plant Health Inspection Service, Veterinary Services, Centers for Epidemiology and Animal Health, United States Department of Agriculture, 2150 Centre Avenue, Building MS 2E7, Fort Collins, CO 80521, USA. david.a.dargatz@aphis.usda.gov |
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English |
Summary Language |
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Abbreviated Series Title |
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Series Issue |
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Edition |
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| ISSN |
0749-0739 |
ISBN |
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Medium |
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| Area |
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Expedition |
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Conference |
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| Notes |
PMID:15519820 |
Approved |
no |
| Call Number |
Equine Behaviour @ team @ |
Serial |
2632 |
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| Author |
Gould, J.L. |
| Title |
Animal cognition |
Type |
Journal Article |
| Year |
2004 |
Publication |
Current Biology : CB |
Abbreviated Journal |
Curr Biol |
| Volume |
14 |
Issue |
10 |
Pages |
R372-5 |
| Keywords |
Animals; Awareness; Behavior, Animal/*physiology; Cognition/*physiology; Concept Formation; Decision Making; Instinct; Intelligence/*physiology; Learning/*physiology; Species Specificity |
| Abstract |
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| Address |
Department of Ecology and Evolutionary Biology, Princeton University, Princeton, New Jersey 08544, USA. gould@princeton.edu |
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Place of Publication |
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English |
Summary Language |
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Original Title |
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Series Title |
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Abbreviated Series Title |
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Series Issue |
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Edition |
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| ISSN |
0960-9822 |
ISBN |
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Medium |
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Expedition |
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Conference |
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| Notes |
PMID:15186759 |
Approved |
no |
| Call Number |
Equine Behaviour @ team @ |
Serial |
4169 |
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| Author |
Panksepp, J. |
| Title |
Affective consciousness: Core emotional feelings in animals and humans |
Type |
Journal Article |
| Year |
2005 |
Publication |
Consciousness and Cognition |
Abbreviated Journal |
Conscious Cogn |
| Volume |
14 |
Issue |
1 |
Pages |
30-80 |
| Keywords |
Affect/*physiology; Animals; Bonding, Human-Pet; Brain/*physiology; Consciousness/*physiology; Fear; Humans; Limbic System/physiology; Social Behavior; Species Specificity; Unconscious (Psychology) |
| Abstract |
The position advanced in this paper is that the bedrock of emotional feelings is contained within the evolved emotional action apparatus of mammalian brains. This dual-aspect monism approach to brain-mind functions, which asserts that emotional feelings may reflect the neurodynamics of brain systems that generate instinctual emotional behaviors, saves us from various conceptual conundrums. In coarse form, primary process affective consciousness seems to be fundamentally an unconditional “gift of nature” rather than an acquired skill, even though those systems facilitate skill acquisition via various felt reinforcements. Affective consciousness, being a comparatively intrinsic function of the brain, shared homologously by all mammalian species, should be the easiest variant of consciousness to study in animals. This is not to deny that some secondary processes (e.g., awareness of feelings in the generation of behavioral choices) cannot be evaluated in animals with sufficiently clever behavioral learning procedures, as with place-preference procedures and the analysis of changes in learned behaviors after one has induced re-valuation of incentives. Rather, the claim is that a direct neuroscientific study of primary process emotional/affective states is best achieved through the study of the intrinsic (“instinctual”), albeit experientially refined, emotional action tendencies of other animals. In this view, core emotional feelings may reflect the neurodynamic attractor landscapes of a variety of extended trans-diencephalic, limbic emotional action systems-including SEEKING, FEAR, RAGE, LUST, CARE, PANIC, and PLAY. Through a study of these brain systems, the neural infrastructure of human and animal affective consciousness may be revealed. Emotional feelings are instantiated in large-scale neurodynamics that can be most effectively monitored via the ethological analysis of emotional action tendencies and the accompanying brain neurochemical/electrical changes. The intrinsic coherence of such emotional responses is demonstrated by the fact that they can be provoked by electrical and chemical stimulation of specific brain zones-effects that are affectively laden. For substantive progress in this emerging research arena, animal brain researchers need to discuss affective brain functions more openly. Secondary awareness processes, because of their more conditional, contextually situated nature, are more difficult to understand in any neuroscientific detail. In other words, the information-processing brain functions, critical for cognitive consciousness, are harder to study in other animals than the more homologous emotional/motivational affective state functions of the brain. |
| Address |
Department of Psychology, Bowling Green State University, Bowling Green, OH 43403, USA. jpankse@bgnet.bgsu.ed |
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Place of Publication |
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Editor |
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English |
Summary Language |
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Original Title |
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Series Title |
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Abbreviated Series Title |
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Series Issue |
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Edition |
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| ISSN |
1053-8100 |
ISBN |
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Medium |
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| Area |
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Expedition |
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Conference |
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| Notes |
PMID:15766890 |
Approved |
no |
| Call Number |
Equine Behaviour @ team @ |
Serial |
4159 |
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| Author |
Dauphin, G.; Zientara, S.; Zeller, H.; Murgue, B. |
| Title |
West Nile: worldwide current situation in animals and humans |
Type |
Journal Article |
| Year |
2004 |
Publication |
Comparative Immunology, Microbiology and Infectious Diseases |
Abbreviated Journal |
Comp Immunol Microbiol Infect Dis |
| Volume |
27 |
Issue |
5 |
Pages |
343-355 |
| Keywords |
Americas/epidemiology; Animals; Birds/virology; Culex/*virology; *Disease Outbreaks; Disease Reservoirs; Europe/epidemiology; Horses/virology; Humans; Insect Vectors/*virology; Middle East/epidemiology; West Nile Fever/*epidemiology/*veterinary/virology; West Nile virus/*growth & development |
| Abstract |
West Nile (WN) virus is a mosquito-borne flavivirus that is native to Africa, Europe, and Western Asia. It mainly circulates among birds, but can infect many species of mammals, as well as amphibians and reptiles. Epidemics can occur in rural as well as urban areas. Transmission of WN virus, sometimes involving significant mortality in humans and horses, has been documented at erratic intervals in many countries, but never in the New World until it appeared in New York City in 1999. During the next four summers it spread with incredible speed to large portions of 46 US states, and to Canada, Mexico, Central America and the Caribbean. In many respects, WN virus is an outstanding example of a zoonotic pathogen that has leaped geographical barriers and can cause severe disease in human and equine. In Europe, in the past two decades there have been a number of significant outbreaks in several countries. However, very little is known of the ecology and natural history of WN virus transmission in Europe and most WN outbreaks in humans and animals remain unpredictable and difficult to control. |
| Address |
AFSSA Alfort, UMR1161 (INRA-AFSSA-ENVA), 22 rue Pierre Curie, BP 63, 94703 Maisons-Alfort Cedex, France |
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English |
Summary Language |
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Original Title |
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Series Title |
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Abbreviated Series Title |
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Series Issue |
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Edition |
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| ISSN |
0147-9571 |
ISBN |
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Medium |
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Expedition |
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Conference |
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| Notes |
PMID:15225984 |
Approved |
no |
| Call Number |
Equine Behaviour @ team @ |
Serial |
2635 |
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| Author |
Nelson, D.M.; Gardner, I.A.; Chiles, R.F.; Balasuriya, U.B.; Eldridge, B.F.; Scott, T.W.; Reisen, W.K.; James Maclachlan, N. |
| Title |
Prevalence of antibodies against Saint Louis encephalitis and Jamestown Canyon viruses in California horses |
Type |
Journal Article |
| Year |
2004 |
Publication |
Comparative Immunology, Microbiology and Infectious Diseases |
Abbreviated Journal |
Comp Immunol Microbiol Infect Dis |
| Volume |
27 |
Issue |
3 |
Pages |
209-215 |
| Keywords |
Animals; Antibodies, Viral/*blood; California/epidemiology; Encephalitis Virus, California/*immunology/isolation & purification; Encephalitis Virus, St. Louis/*immunology/isolation & purification; Encephalitis, St. Louis/epidemiology/immunology/*veterinary/virology; Female; Horse Diseases/epidemiology/immunology/*virology; Horses; Logistic Models; Male; Neutralization Tests/veterinary; Polyomavirus Infections/epidemiology/immunology/*veterinary/virology; Questionnaires; Seroepidemiologic Studies; Tumor Virus Infections/epidemiology/immunology/*veterinary/virology |
| Abstract |
Jamestown Canyon (JC) and Saint Louis encephalitis (SLE) viruses are mosquito-transmitted viruses that have long been present in California. The objective of this study was to determine the seroprevalence of these two viruses in horses prior to the introduction of West Nile (WN) virus. Approximately 15% of serum samples collected in 1998 from 425 horses on 44 equine operations horses throughout California had serum antibodies to JC virus, whereas antibodies were not detected to SLE virus. The results indicate that horses in California were commonly infected prior to 1998 with mosquito-transmitted Bunyaviruses that are identical or closely related to JC virus, but not with SLE virus. The different seroprevalence of SLE and JC viruses in horses likely reflects the unique ecology of each virus, and it is predicted that WN virus will have a wider distribution in California than closely related SLE virus. |
| Address |
Animal and Plant Health Inspection Service, Veterinary Services, U.S. Department of Agriculture, California and Nevada Area Office, 9850 Micron Avenue, Suite E, Sacramento, CA 95827, USA |
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English |
Summary Language |
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Original Title |
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Series Title |
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Abbreviated Series Title |
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Series Issue |
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Edition |
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| ISSN |
0147-9571 |
ISBN |
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Medium |
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Expedition |
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Conference |
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| Notes |
PMID:15001316 |
Approved |
no |
| Call Number |
Equine Behaviour @ team @ |
Serial |
2637 |
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| Author |
Rosa, P.A.J.; Azevedo, A.M.; Aires-Barros, M.R. |
| Title |
Application of central composite design to the optimisation of aqueous two-phase extraction of human antibodies |
Type |
Journal Article |
| Year |
2007 |
Publication |
Journal of Chromatography. A |
Abbreviated Journal |
J Chromatogr A |
| Volume |
1141 |
Issue |
1 |
Pages |
50-60 |
| Keywords |
Analysis of Variance; Animals; Antibodies/*chemistry/*isolation & purification; Buffers; Chemical Fractionation/*methods; Horses; Humans; Hydrophobicity; Isoelectric Point; Models, Biological; Molecular Weight; Myoglobin/chemistry/isolation & purification; Osmolar Concentration; Phase Transition; Polyethylene Glycols; Serum Albumin/chemistry/isolation & purification; Sodium Chloride |
| Abstract |
The partition of human antibodies in aqueous two-phase systems (ATPSs) of polyethylene glycol (PEG) and phosphate was systematically studied using first pure proteins systems and then an artificial mixture of proteins containing 1mg/ml human immunoglobulin G (IgG), 10mg/ml serum albumin and 2mg/ml myoglobin. Preliminary results obtained using pure proteins systems indicated that the PEG molecular weight and concentration, the pH value and the salts concentration had a pronounced effect on the partitioning behaviour of all proteins. For high ionic strengths and pH values higher than the isoelectric point (pI) of the contaminant proteins, IgG could be selectively recovered on the top phase. According to these results, a face centred composite design was performed in order to optimise the purification of IgG from the mixture of proteins. The optimal conditions for the isolation of IgG were observed for high concentrations of NaCl and low concentrations of both phase forming components. The best purification was achieved using an ATPS containing 8% (w/w) PEG 3350, 10% (w/w) phosphate pH 6 and 15% (w/w) NaCl. A recovery yield of 101+/-7%, a purity of 99+/-0% and a yield of native IgG of 97+/-4% were obtained. Back extraction studies of IgG to a new phosphate phase were performed and higher yields were obtained using 10% phosphate buffer at pH 6. The total extraction yield was 76% and the purity 100%. |
| Address |
IBB Institute for Biotechnology and Bioengineering, Centre for Biological and Chemical Engineering, Instituto Superior Tecnico, Av Rovisco Pais, 1049-001 Lisbon, Portugal |
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Place of Publication |
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English |
Summary Language |
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Original Title |
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Series Title |
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Abbreviated Series Title |
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Series Issue |
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Edition |
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| ISSN |
0021-9673 |
ISBN |
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Medium |
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Expedition |
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Conference |
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| Notes |
PMID:17196214 |
Approved |
no |
| Call Number |
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Serial |
1842 |
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