Records |
Author |
Hinson, R.E. |
Title ![sorted by Title field, ascending order (up)](img/sort_asc.gif) |
Effects of UCS preexposure on excitatory and inhibitory rabbit eyelid conditioning: an associative effect of conditioned contextual stimuli |
Type |
Journal Article |
Year |
1982 |
Publication |
Journal of Experimental Psychology. Animal Behavior Processes |
Abbreviated Journal |
J Exp Psychol Anim Behav Process |
Volume |
8 |
Issue |
1 |
Pages |
49-61 |
Keywords |
Animals; Association Learning; Cognition; *Conditioning, Eyelid; *Inhibition (Psychology); Practice (Psychology); Rabbits; Reaction Time |
Abstract |
Preconditioning experience with the unconditional stimulus (UCS) retards subsequent excitatory conditioning. Three experiments demonstrated that this UCS retardation effect is attenuated by associative manipulations of contextual stimuli of the UCS preexposure environment. The UCS retardation effect was reduced by (a) altering contextual stimuli between preexposure and conditioning (Experiment 1), (b) latently inhibiting contextual stimuli prior to UCS preexposure (Experiment 2), and (c) extinguishing contextual stimuli subsequent to UCS preexposure (Experiment 3). Although UCS preexposure retarded excitatory conditioning, the results of Experiment 4 demonstrated that UCS preexposure facilitated inhibitory conditioning. These results indicate that an association between contextual stimuli and the preexposed UCS contributes to the effects of preconditioning UCS experience on subsequent learning. |
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0097-7403 |
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PMID:7057144 |
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no |
Call Number |
Equine Behaviour @ team @ |
Serial |
2787 |
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Author |
Fiset, S.; Landry, F.; Ouellette, M. |
Title ![sorted by Title field, ascending order (up)](img/sort_asc.gif) |
Egocentric search for disappearing objects in domestic dogs: evidence for a geometric hypothesis of direction |
Type |
Journal Article |
Year |
2006 |
Publication |
Animal Cognition |
Abbreviated Journal |
Anim. Cogn. |
Volume |
9 |
Issue |
1 |
Pages |
1-12 |
Keywords |
Animals; Dogs/*psychology; Female; Form Perception; Male; Mental Recall; *Motion Perception; Orientation; Problem Solving; *Space Perception |
Abstract |
In several species, the ability to locate a disappearing object is an adaptive component of predatory and social behaviour. In domestic dogs, spatial memory for hidden objects is primarily based on an egocentric frame of reference. We investigated the geometric components of egocentric spatial information used by domestic dogs to locate an object they saw move and disappear. In experiment 1, the distance and the direction between the position of the animal and the hiding location were put in conflict. Results showed that the dogs primarily used the directional information between their own spatial coordinates and the target position. In experiment 2, the accuracy of the dogs in finding a hidden object by using directional information was estimated by manipulating the angular deviation between adjacent hiding locations and the position of the animal. Four angular deviations were tested: 5, 7.5, 10 and 15 degrees . Results showed that the performance of the dogs decreased as a function of the angular deviations but it clearly remained well above chance, revealing that the representation of the dogs for direction is precise. In the discussion, we examine how and why domestic dogs determine the direction in which they saw an object disappear. |
Address |
Secteur Sciences Humaines, Universite de Moncton, Campus d'Edmundston, Edmundston, New-Brunswick, Canada E3V 2S8. sfiset@umce.ca |
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1435-9448 |
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PMID:15750805 |
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no |
Call Number |
Equine Behaviour @ team @ |
Serial |
2489 |
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Author |
Wilson, M.T.; Silvestrini, M.C.; Morpurgo, L.; Brunori, M. |
Title ![sorted by Title field, ascending order (up)](img/sort_asc.gif) |
Electron transfer kinetics between Rhus vernicifera stellacyanin and cytochrome c (horse heart cytochrome c and Pseudomonas cytochrome c551) |
Type |
Journal Article |
Year |
1979 |
Publication |
Journal of Inorganic Biochemistry |
Abbreviated Journal |
J Inorg Biochem |
Volume |
11 |
Issue |
2 |
Pages |
95-100 |
Keywords |
Animals; Copper; Cytochrome c Group/*metabolism; Electron Transport; Kinetics; Metalloproteins/*metabolism; Plant Proteins/*metabolism; *Plants, Toxic; Pseudomonas aeruginosa/*metabolism; Toxicodendron/*metabolism |
Abstract |
The electron transfer reactions between Rhus vernicifera stellacyanin and either horse heart cytochrome c or Pseudomonas aeruginosa cytochrome c551 were investigated by rapid reaction techniques. The time course of electron transfer is monophasic under all conditions, and thus consistent with a simple formulation of the reaction. Both stopped-flow and temperature-jump experiments yield equilibrium constants in reasonable agreement with values calculated from the redox potentials. The differences in reaction rate between the two cytochromes and stellacyanin are discussed in terms of the Marcus theory. |
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ISSN |
0162-0134 |
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Notes |
PMID:228006 |
Approved |
no |
Call Number |
refbase @ user @ |
Serial |
3879 |
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Author |
Shoshani, J.; Kupsky, W.J.; Marchant, G.H. |
Title ![sorted by Title field, ascending order (up)](img/sort_asc.gif) |
Elephant brain. Part I: gross morphology, functions, comparative anatomy, and evolution |
Type |
Journal Article |
Year |
2006 |
Publication |
Brain Research Bulletin |
Abbreviated Journal |
Brain Res Bull |
Volume |
70 |
Issue |
2 |
Pages |
124-157 |
Keywords |
Animals; Brain/*anatomy & histology/blood supply/*physiology; Cats; Chinchilla; Elephants/*anatomy & histology/*physiology; Equidae; *Evolution; Female; Guinea Pigs; Haplorhini; Humans; Hyraxes; Male; Pan troglodytes; Sheep; Wolves |
Abstract |
We report morphological data on brains of four African, Loxodonta africana, and three Asian elephants, Elephas maximus, and compare findings to literature. Brains exhibit a gyral pattern more complex and with more numerous gyri than in primates, humans included, and in carnivores, but less complex than in cetaceans. Cerebral frontal, parietal, temporal, limbic, and insular lobes are well developed, whereas the occipital lobe is relatively small. The insula is not as opercularized as in man. The temporal lobe is disproportionately large and expands laterally. Humans and elephants have three parallel temporal gyri: superior, middle, and inferior. Hippocampal sizes in elephants and humans are comparable, but proportionally smaller in elephant. A possible carotid rete was observed at the base of the brain. Brain size appears to be related to body size, ecology, sociality, and longevity. Elephant adult brain averages 4783 g, the largest among living and extinct terrestrial mammals; elephant neonate brain averages 50% of its adult brain weight (25% in humans). Cerebellar weight averages 18.6% of brain (1.8 times larger than in humans). During evolution, encephalization quotient has increased by 10-fold (0.2 for extinct Moeritherium, approximately 2.0 for extant elephants). We present 20 figures of the elephant brain, 16 of which contain new material. Similarities between human and elephant brains could be due to convergent evolution; both display mosaic characters and are highly derived mammals. Humans and elephants use and make tools and show a range of complex learning skills and behaviors. In elephants, the large amount of cerebral cortex, especially in the temporal lobe, and the well-developed olfactory system, structures associated with complex learning and behavioral functions in humans, may provide the substrate for such complex skills and behavior. |
Address |
Department of Biology, University of Asmara, P.O. Box 1220, Asmara, Eritrea (Horn of Africa). hezy@bio.uoa.edu.er |
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English |
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Edition |
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ISSN |
0361-9230 |
ISBN |
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Notes |
PMID:16782503 |
Approved |
no |
Call Number |
Equine Behaviour @ team @ |
Serial |
2623 |
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Author |
Preston, S.D.; de Waal, F.B.M. |
Title ![sorted by Title field, ascending order (up)](img/sort_asc.gif) |
Empathy: Its ultimate and proximate bases |
Type |
Journal Article |
Year |
2002 |
Publication |
Behavioral and Brain Sciences |
Abbreviated Journal |
Behav Brain Sci |
Volume |
25 |
Issue |
1 |
Pages |
1-20; discussion 20-71 |
Keywords |
Adult; Animals; Child; Emotions/physiology; *Empathy; Evolution; Haplorhini; Helping Behavior; Humans; Mental Disorders/physiopathology/psychology; Morals; Personality Development; Phylogeny; Prefrontal Cortex/physiopathology; Socialization |
Abstract |
There is disagreement in the literature about the exact nature of the phenomenon of empathy. There are emotional, cognitive, and conditioning views, applying in varying degrees across species. An adequate description of the ultimate and proximate mechanism can integrate these views. Proximately, the perception of an object's state activates the subject's corresponding representations, which in turn activate somatic and autonomic responses. This mechanism supports basic behaviors (e.g., alarm, social facilitation, vicariousness of emotions, mother-infant responsiveness, and the modeling of competitors and predators) that are crucial for the reproductive success of animals living in groups. The Perception-Action Model (PAM), together with an understanding of how representations change with experience, can explain the major empirical effects in the literature (similarity, familiarity, past experience, explicit teaching, and salience). It can also predict a variety of empathy disorders. The interaction between the PAM and prefrontal functioning can also explain different levels of empathy across species and age groups. This view can advance our evolutionary understanding of empathy beyond inclusive fitness and reciprocal altruism and can explain different levels of empathy across individuals, species, stages of development, and situations. |
Address |
University of Iowa Hospital and Clinics, 2RCP-Neurology Clinic, Iowa City, IA 52242. stephanie-d-preston@uiowa.edu |
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ISSN |
0140-525X |
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Notes |
PMID:12625087 |
Approved |
no |
Call Number |
refbase @ user @ |
Serial |
181 |
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Author |
Moehlman, P.D. |
Title ![sorted by Title field, ascending order (up)](img/sort_asc.gif) |
Endangered wild equids |
Type |
Journal Article |
Year |
2005 |
Publication |
Scientific American |
Abbreviated Journal |
Sci Am |
Volume |
292 |
Issue |
3 |
Pages |
74-81 |
Keywords |
Africa; Americas; Animals; *Animals, Wild/physiology; Asia; *Conservation of Energy Resources; Environment; *Equidae/physiology; Food Chain; Humans; Male; Reproduction |
Abstract |
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Address |
IUCN-The World Conservation Union/Species Survival Commission Equid Specialist Group |
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English |
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ISSN |
0036-8733 |
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Notes |
PMID:15859216 |
Approved |
no |
Call Number |
refbase @ user @ |
Serial |
551 |
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Author |
Devienne, M.F.; Guezennec, C.Y. |
Title ![sorted by Title field, ascending order (up)](img/sort_asc.gif) |
Energy expenditure of horse riding |
Type |
Journal Article |
Year |
2000 |
Publication |
European Journal of Applied Physiology |
Abbreviated Journal |
Eur J Appl Physiol |
Volume |
82 |
Issue |
5-6 |
Pages |
499-503 |
Keywords |
Adult; Animals; Energy Metabolism/*physiology; Exercise/*physiology; Exercise Test; Female; Hemodynamic Processes/physiology; Horses; Humans; Male; Oxygen Consumption/physiology; Respiratory Mechanics/physiology |
Abstract |
Oxygen consumption (VO2), ventilation (VE) and heart rate (HR) were studied in five recreational riders with a portable oxygen analyser (K2 Cosmed, Rome) telemetric system, during two different experimental riding sessions. The first one was a dressage session in which the rider successively rode four different horses at a walk, trot and canter. The second one was a jumping training session. Each rider rode two horses, one known and one unknown. The physiological parameters were measured during warm up at a canter in suspension and when jumping an isolated obstacle at a trot and canter. This session was concluded by a jumping course with 12 obstacles. The data show a progressive increase in VO2 during the dressage session from a mean value of 0.70 (0.18) l x min(-1) [mean (SD)] at a walk, to 1.47 (0.28) l x min(-1) at a trot, and 1.9 (0.3) l x min(-1) at a canter. During the jumping session, rider VO2 was 2 (0.33) l x min(-1) with a mean HR of 155 beats x min(-1) during canter in suspension, obstacle trot and obstacle canter. The jumping course significantly enhanced VO2 and HR up to mean values of 2.40 (0.35) l x min(-1) and 176 beats x min(-1), respectively. The comparison among horses and riders during the dressage session shows differences in energy expenditure according to the horse for the same rider and between riders. During the jumping session, there was no statistical difference between riders riding known and unknown horses. In conclusion these data confirm that riding induces a significant increase in energy expenditure. During jumping, a mean value of 75% VO2max was reached. Therefore, a good aerobic capacity seems to be a factor determining riding performance in competitions. Regular riding practice and additional physical training are recommended to enhance the physical fitness of competitive riders. |
Address |
Universite Paris XII-STAPS-61, Creteil, France. Mfdevienne@aol.com |
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1439-6319 |
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PMID:10985607 |
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no |
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Equine Behaviour @ team @ |
Serial |
3731 |
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Author |
Guo, G.L.; Moffit, J.S.; Nicol, C.J.; Ward, J.M.; Aleksunes, L.A.; Slitt, A.L.; Kliewer, S.A.; Manautou, J.E.; Gonzalez, F.J. |
Title ![sorted by Title field, ascending order (up)](img/sort_asc.gif) |
Enhanced acetaminophen toxicity by activation of the pregnane X receptor |
Type |
Journal Article |
Year |
2004 |
Publication |
Toxicological sciences : an official journal of the Society of Toxicology |
Abbreviated Journal |
Toxicol Sci |
Volume |
82 |
Issue |
2 |
Pages |
374-380 |
Keywords |
Acetaminophen/pharmacokinetics/*toxicity; Analgesics, Non-Narcotic/pharmacokinetics/*toxicity; Animals; Aryl Hydrocarbon Hydroxylases/biosynthesis; Biotransformation; Blotting, Northern; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP3A; Membrane Proteins; Mice; Mice, Knockout; Oxidoreductases, N-Demethylating/biosynthesis; Pregnenolone Carbonitrile/pharmacology; Receptors, Cytoplasmic and Nuclear/*drug effects; Receptors, Steroid/*drug effects; Sulfhydryl Compounds/metabolism |
Abstract |
The pregnane X receptor (PXR) is a ligand-activated transcription factor and member of the nuclear receptor superfamily. Activation of PXR represents an important mechanism for the induction of cytochrome P450 3A (CYP3A) enzymes that can convert acetaminophen (APAP) to its toxic intermediate metabolite, N-acetyl-p-benzoquinone imine (NAPQI). Therefore, it was hypothesized that activation of PXR plays a major role in APAP-induced hepatotoxicity. Pretreatment with the PXR activator, pregnenolone 16alpha-carbonitrile (PCN), markedly enhanced APAP-induced hepatic injury, as revealed by increased serum ALT levels and hepatic centrilobular necrosis, in wild-type but not in PXR-null mice. Further analysis showed that following PCN treatment, PXR-null mice had lower CYP3A11 expression, decreased NAPQI formation, and increased maintenance of hepatic glutathione content compared to wild-type mice. Thus, these results suggest that PXR plays a critical role in APAP-induced hepatic toxicity, probably by inducing CYP3A11 expression and hence increasing bioactivation. |
Address |
Laboratory of Metabolism, CCR, NCI, NIH, Bethesda, Maryland 20892, USA |
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ISSN |
1096-6080 |
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PMID:15456926 |
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no |
Call Number |
refbase @ user @ |
Serial |
71 |
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Author |
Barwick, R.S.; Mohammed, H.O.; McDonough, P.L.; White, M.E. |
Title ![sorted by Title field, ascending order (up)](img/sort_asc.gif) |
Epidemiologic features of equine Leptospira interrogans of human significance |
Type |
Journal Article |
Year |
1998 |
Publication |
Preventive Veterinary Medicine |
Abbreviated Journal |
Prev Vet Med |
Volume |
36 |
Issue |
2 |
Pages |
153-165 |
Keywords |
Animals; Horse Diseases/epidemiology/*microbiology; Horses/microbiology; Humans; *Leptospira interrogans; New York/epidemiology; Weil Disease/epidemiology/microbiology/*veterinary; Zoonoses/epidemiology/*microbiology |
Abstract |
Leptospirosis is a zoonotic bacterial disease caused by Leptospira interrogans. There is a serologic evidence that horses are exposed to L. interrogans and, as a shedder of these organisms, can be a threat to humans. We examined risk factors associated with the risk of testing seropositive to three L. interrogans serovars (L. icterohaemorrhagiae, L. grippotyphosa, and L. canicola) in the horses of New York State, in order to understand the epidemiology of the disease and suggest strategies to control and prevent equine leptospirosis. To carry out this study, blood samples were collected from a random sample of 2551 horses and tested for the presence of antibodies to the above serovars using the microscopic agglutination test. Samples with a titer $100 were considered positive. Clinical and demographic data were collected on each horse, the farms' management practices and ecology. Logistic regression analysis was used to develop a multivariate indexing system and to identify factors significantly associated with the risk of leptospirosis. Four indices were developed based on the possible sources of exposure: rodent exposure index; wildlife exposure index; soil and water index; and management index. The soil and water index was significantly associated with the risk of exposure to all three serovars. Management was positively associated with L. icterohaemorrhagiae and L. canicola. Density of horses turned out together was positively associated with the risk of exposure to L. grippotyphosa. We concluded that indirect exposure of horses to L. interrogans through contaminated soil and water appears to be significantly associated with the risk of exposure to all three serovars. Management appears to play an important role in the exposure to L. interrogans. Modification of management practices might reduce the horses' risk of exposure and hopefully minimize the human hazards. |
Address |
Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA |
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0167-5877 |
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PMID:9762736 |
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no |
Call Number |
Equine Behaviour @ team @ |
Serial |
2653 |
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Author |
Schwartz, B.L.; Evans, S. |
Title ![sorted by Title field, ascending order (up)](img/sort_asc.gif) |
Episodic memory in primates |
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Journal Article |
Year |
2001 |
Publication |
American journal of primatology |
Abbreviated Journal |
Am. J. Primatol. |
Volume |
55 |
Issue |
2 |
Pages |
71-85 |
Keywords |
Animals; Behavior, Animal; *Discrimination Learning; Hominidae/*psychology; Humans; *Memory; Self Concept |
Abstract |
Episodic memory refers to a system of memory with the capacity to recollect specific events from an individual's life. Some psychologists have suggested that episodic memory is a uniquely human phenomenon. We challenge that idea and present evidence that great apes and other primates may possess episodic-like memory. We review criteria developed to assess episodic-like memory in nonhumans, and how they apply to primates. In particular, we discuss the criteria of Clayton et al. [2001], who stated that episodic-like memory is based on the retrieval of multiple and integrated components of an event. We then review eight studies examining memory in great apes and apply the Clayton et al. criteria to each of them. We summarize the evidence that is compatible with the existence of episodic-like memory, although none of the data completely satisfy the Clayton et al. criteria. Morover, feelings of pastness and feelings of confidence, which mark episodic memory in humans, have not been empirically addressed in nonhuman primates. Future studies should be directed at these aspects of memory in primates. We speculate on the functional significance of episodic memory in nonhuman primates. |
Address |
Dept of Psychology, Florida International University, Miami, Florida 33199, USA. SchwartB@fiu.edu |
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0275-2565 |
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PMID:11668526 |
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no |
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Equine Behaviour @ team @ |
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4115 |
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