| Records |
| Author |
Machnik, M.; Hegger, I.; Kietzmann, M.; Thevis, M.; Guddat, S.; Schanzer, W. |
Title  |
Pharmacokinetics of altrenogest in horses |
Type |
Journal Article |
| Year |
2007 |
Publication |
Journal of Veterinary Pharmacology and Therapeutics |
Abbreviated Journal |
J Vet Pharmacol Ther |
| Volume |
30 |
Issue |
1 |
Pages |
86-90 |
| Keywords |
Administration, Oral; Animals; Chromatography, Liquid/veterinary; Doping in Sports/prevention & control; Horses/*metabolism; Male; Mass Spectrometry/veterinary; Progesterone Congeners/administration & dosage/blood/*pharmacokinetics/urine; Reproducibility of Results; Substance Abuse Detection/veterinary; Trenbolone/administration & dosage/*analogs & derivatives/blood/pharmacokinetics/urine |
| Abstract |
The Federation Equestre Internationale has permitted the use of altrenogest in mares for the control of oestrus. However, altrenogest is also suspicious to misuse in competition horses for its potential anabolic effects and suppression of typical male behaviour, and thus is a controlled drug. To investigate the pharmacokinetics of altrenogest in horses we conducted an elimination study. Five oral doses of 44 mug/kg altrenogest were administered to 10 horses at a dose interval of 24 h. Following administration blood and urine samples were collected at appropriate intervals. Altrenogest concentrations were measured by liquid chromatography-tandem mass spectrometry. The plasma levels of altrenogest reached maximal concentrations of 23-75 ng/mL. Baseline values were achieved within 3 days after the final administration. Urine peak concentrations of total altrenogest ranged from 823 to 3895 ng/mL. Twelve days after the final administration concentrations were below the limit of detection (ca 2 ng/mL). |
| Address |
Institute of Biochemistry, German Sport University, Cologne, Germany. m.machnik@biochem.dshs-koeln.de |
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| Language |
English |
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Series Issue |
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Edition |
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| ISSN |
0140-7783 |
ISBN |
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Medium |
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| Notes |
PMID:17217407 |
Approved |
no |
| Call Number |
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Serial |
1841 |
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| Author |
Krcmar, S.; Mikuska, A.; Merdic, E. |
| Title |
Response of Tabanidae (Diptera) to different natural attractants |
Type |
Journal Article |
| Year |
2006 |
Publication |
Journal of Vector Ecology : Journal of the Society for Vector Ecology |
Abbreviated Journal |
J Vector Ecol |
| Volume |
31 |
Issue |
2 |
Pages |
262-265 |
| Keywords |
Animals; Appetitive Behavior/*physiology; Cattle/urine; Diptera/*physiology; Female; Horses/urine; Insect Control/methods; Sheep/urine; Swine/urine; Urine/*physiology |
| Abstract |
The response of female tabanids to natural attractants was studied in the Monjoros Forest along the Nature Park Kopacki rit in eastern Croatia. Tabanids were caught in canopy traps baited with either aged cow, horse, sheep, or pig urine and also in unbaited traps. Tabanids were collected in a significantly higher numbers in traps baited with natural attractants compared to unbaited traps. The number of females of Tabanus bromius, Tabanus maculicornis, Tabanus tergestinus, and Hybomitra bimaculata collected from canopy traps baited with cow urine and traps baited with other natural attractants differed significantly. Females of Haematopota pluvialis were also collected more frequently in canopy traps baited with aged cow urine than in those with aged horse urine, but this difference was not significant. However, the number of females of Haematopota pluvialis collected from canopy traps baited with other natural attractants (sheep and pig urine) differed significantly when compared with aged cow urine baited traps. Canopy traps baited with aged cow urine collected significantly more Tabanus sudeticus than did traps baited with aged pig urine. Finally, the aged cow urine baited canopy traps collected 51 times more tabanids than unbaited traps, while aged horse, aged sheep, and aged pig urine baited traps collected 36, 30, and 22 times as many tabanids, respectively, than unbaited traps. |
| Address |
Department of Biology, JJ Strossmayer University, Lj. Gaja 6, HR-31000 Osijek, Croatia |
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English |
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Edition |
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| ISSN |
1081-1710 |
ISBN |
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Medium |
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| Notes |
PMID:17249343 |
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no |
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Serial |
1836 |
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| Author |
Alexander, F.; Davies, M.E. |
| Title |
Studies on vitamin B12 in the horse |
Type |
Journal Article |
| Year |
1969 |
Publication |
The British veterinary journal |
Abbreviated Journal |
Br. Vet. J. |
| Volume |
125 |
Issue |
4 |
Pages |
169-176 |
| Keywords |
Animals; Biological Assay; Cattle; Chickens; Feces/analysis; Horses/*metabolism; Humans; Lactobacillus/metabolism; Rabbits; Rats; Sheep; Urine/analysis; Vitamin B 12/*analysis |
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English |
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Edition |
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| ISSN |
0007-1935 |
ISBN |
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| Notes |
PMID:5814055 |
Approved |
no |
| Call Number |
refbase @ user @ |
Serial |
116 |
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| Author |
Alexander, F. |
| Title |
The effect of some anti-diarrhoeal drugs on intestinal transit and faecal excretion of water and electrolytes in the horse |
Type |
Journal Article |
| Year |
1978 |
Publication |
Equine veterinary journal |
Abbreviated Journal |
Equine Vet J |
| Volume |
10 |
Issue |
4 |
Pages |
229-234 |
| Keywords |
Animals; Antidiarrheals/*pharmacology; Atropine/pharmacology; Electrolytes/*analysis/urine; Feces/*analysis; Gastrointestinal Motility/*drug effects; Horses/*metabolism/physiology; Loperamide/pharmacology; Male; Meperidine/pharmacology; Morphine/pharmacology; Opium/pharmacology; Water/*analysis |
| Abstract |
The effect of morphine, Tinct. opii, loperamide, pethidine and atropine on intestinal transit and the faecal and urinary excretion of water and electrolytes was studied in ponies. The rate of passage of a particulate marker was slowed by morphine, hastened then slowed by loperamide and Tinct. opii, and hastened by atropine. The liquid marker was slowed by Tinct. opii and hastened then slowed by the other drugs. Only loperamide decreased the faecal sodium excretion. This drug also decreased faecal water and weight; it appeared worthy of clinical trial in diarrhoea. Tinct. opii decreased by morphine, pethidine and atropine increased faecal water. |
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English |
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Edition |
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| ISSN |
0425-1644 |
ISBN |
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Medium |
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| Notes |
PMID:738263 |
Approved |
no |
| Call Number |
refbase @ user @ |
Serial |
110 |
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| Author |
Brennan, P.A. |
| Title |
The nose knows who's who: chemosensory individuality and mate recognition in mice |
Type |
Journal Article |
| Year |
2004 |
Publication |
Hormones and Behavior |
Abbreviated Journal |
Horm Behav |
| Volume |
46 |
Issue |
3 |
Pages |
231-240 |
| Keywords |
Animals; Chemoreceptors/physiology; Discrimination Learning/*physiology; Embryo Implantation/physiology; Female; Individuality; Major Histocompatibility Complex/physiology; Male; Mice; Neurons, Afferent/physiology; Nose/cytology/physiology; Perception/physiology; Pregnancy; Pregnancy Maintenance/physiology; Pregnancy, Animal/*physiology; Receptors, Odorant/*physiology; Recognition (Psychology)/*physiology; Sexual Behavior, Animal/*physiology; Smell/*physiology; Urine/physiology; Vomeronasal Organ/cytology/physiology |
| Abstract |
Individual recognition is an important component of behaviors, such as mate choice and maternal bonding that are vital for reproductive success. This article highlights recent developments in our understanding of the chemosensory cues and the neural pathways involved in individuality discrimination in rodents. There appear to be several types of chemosensory signal of individuality that are influenced by the highly polymorphic families of major histocompatibility complex (MHC) proteins or major urinary proteins (MUPs). Both have the capability of binding small molecules and may influence the individual profile of these chemosignals in biological fluids such as urine, skin secretions, or saliva. Moreover, these proteins, or peptides associated with them, can be taken up into the vomeronasal organ (VNO) where they can potentially interact directly with the vomeronasal receptors. This is particularly interesting given the expression of major histocompatibility complex Ib proteins by the V2R class of vomeronasal receptor and the highly selective responses of accessory olfactory bulb (AOB) mitral cells to strain identity. These findings are consistent with the role of the vomeronasal system in mediating individual discrimination that allows mate recognition in the context of the pregnancy block effect. This is hypothesized to involve a selective increase in the inhibitory control of mitral cells in the accessory olfactory bulb at the first level of processing of the vomeronasal stimulus. |
| Address |
Sub-Department of Animal Behaviour, University of Cambridge, Madingley, Cambridge CB3 8AA, UK. pab23@cus.cam.ac.uk |
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English |
Summary Language |
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Edition |
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| ISSN |
0018-506X |
ISBN |
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| Notes |
PMID:15325224 |
Approved |
no |
| Call Number |
Equine Behaviour @ team @ |
Serial |
4191 |
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| Author |
Stahlbaum, C.C.; Houpt, K.A. |
| Title |
The role of the Flehmen response in the behavioral repertoire of the stallion |
Type |
Journal Article |
| Year |
1989 |
Publication |
Physiology & behavior |
Abbreviated Journal |
Physiol. Behav. |
| Volume |
45 |
Issue |
6 |
Pages |
1207-1214 |
| Keywords |
Animals; Behavior, Animal/*physiology; Circadian Rhythm; Discrimination (Psychology)/physiology; Estrus; Feces; Female; Horses/*physiology; Male; Sexual Behavior, Animal/*physiology; Smell/*physiology; Taste/physiology; Urine |
| Abstract |
The role of the Flehmen response in equine behavior was investigated under field and laboratory conditions. In Experiment 1, a field study made of five stallions on pasture with between three and eighteen mares each during the season indicated the following: 1) The Flehmen response was most frequently preceded by nasal, rather than oral, investigation of substances; 2) The stallions' rate of Flehmen varied with the estrous cycles of the mares; 3) The rate of Flehmen response did not show a variation with time of day; and 4) The Flehmen response was most frequently followed by marking behaviors rather than courtship behaviors. The results suggest that the Flehmen response is not an immediate component of sexual behavior, e.g., courtship of the stallion but may be involved in the overall monitoring of the mare's estrous cycle. Therefore the Flehmen response may contribute to the chemosensory priming of the stallion for reproduction. In Experiment 2 stallions were presented with urine or feces of mares in various stages of the reproductive cycle as well as with their own or other males' urine or feces. The occurrence of sniffing and Flehmen was used to determine the discriminatory ability of the stallions. Stallions can differentiate the sex of a horse on the basis of its feces alone, but cannot differentiate on the basis of urine. This ability may explain the function of fecal marking behavior of stallions. |
| Address |
New York State College of Veterinary Medicine, Cornell University, Ithaca 14853 |
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English |
Summary Language |
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Abbreviated Series Title |
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Edition |
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| ISSN |
0031-9384 |
ISBN |
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| Notes |
PMID:2813545 |
Approved |
no |
| Call Number |
refbase @ user @ |
Serial |
44 |
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| Author |
Alexander, F.; Horner, M.W.; Moss, M.S. |
| Title |
The salivary secretion and clearance in the horse of chloral hydrate and its metabolites |
Type |
Journal Article |
| Year |
1967 |
Publication |
Biochemical pharmacology |
Abbreviated Journal |
Biochem Pharmacol |
| Volume |
16 |
Issue |
7 |
Pages |
1305-1311 |
| Keywords |
Animals; Chloral Hydrate/blood/*metabolism/urine; Chromatography, Gas; Ethanol/blood/urine; Horses; Male; Parotid Gland/metabolism; Saliva/*analysis; Trichloroacetic Acid/blood/urine |
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English |
Summary Language |
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Abbreviated Series Title |
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Series Issue |
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Edition |
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| ISSN |
0006-2952 |
ISBN |
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Conference |
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| Notes |
PMID:6053598 |
Approved |
no |
| Call Number |
refbase @ user @ |
Serial |
118 |
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| Author |
Ziegler, W.H. |
| Title |
[Endocrinological studies in arterial hypertension. Search for phaeochromocytoma] |
Type |
Journal Article |
| Year |
1976 |
Publication |
Schweizerische Medizinische Wochenschrift |
Abbreviated Journal |
Schweiz Med Wochenschr |
| Volume |
106 |
Issue |
34 |
Pages |
1148-1150 |
| Keywords |
Angiography; Blood Volume; Catecholamines/urine; Glucagon/diagnostic use; Histamine/diagnostic use; Humans; Hydrogen-Ion Concentration; Hypertension/*etiology; Methods; Pheochromocytoma/*complications/diagnosis; Tyramine/diagnostic use |
| Abstract |
Elevated urinary catecholamines and their metabolites are the only findings which confirm the presence of pheochromocytoma. This examination is of particular interest if carried out in urine produced after spontaneous hypertensive episodes. Pharmacologic tests when carried out under standard conditions have proven to be a reliable aid in cases of suspected pheochromocytoma. Roentgenographic studies, determination of local plasma catecholamine concentrations and blood volume control should be undertaken in these patients before surgical procedure. |
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German |
Summary Language |
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Original Title |
Endokrinologische Untersuchungen bei arterieller Hypertonie. Suche nach Phaochromozytom |
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Edition |
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| ISSN |
0036-7672 |
ISBN |
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| Notes |
PMID:12561 |
Approved |
no |
| Call Number |
Equine Behaviour @ team @ |
Serial |
4047 |
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