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| Author | Hodgson, D.; Howe, S.; Jeffcott, L.; Reid, S.; Mellor, D.; Higgins, A. | ||||
| Title | Effect of prolonged use of altrenogest on behaviour in mares | Type | |||
| Year | 2005 | Publication | Veterinary journal (London, England : 1997) | Abbreviated Journal | Vet J |
| Volume | 169 | Issue | 1 | Pages | 113-115 |
| Keywords | Administration, Oral; Anabolic Agents/adverse effects/*pharmacology; Animals; Behavior, Animal/*drug effects; Body Constitution/drug effects; Body Weight/drug effects; *Doping in Sports; Female; Horses/*physiology; Social Behavior; Social Dominance; Time Factors; Trenbolone/adverse effects/*analogs & derivatives/*pharmacology | ||||
| Abstract | Erratum in: Vet J. 2005 May;169(3):321. Corrected and republished in: Vet J. 2005 May;169(3):322-5. Oral administration of altrenogest for oestrus suppression in competition horses is believed to be widespread in some equestrian disciplines, and can be administered continuously for several months during a competition season. To examine whether altrenogest has any anabolic or other potential performance enhancing properties that may give a horse an unfair advantage, we examined the effect of oral altrenogest (0.044 mg/kg), given daily for a period of eight weeks, on social hierarchy, activity budget, body-mass and body condition score of 12 sedentary mares. We concluded that prolonged oral administration of altrenogest at recommended dose rates to sedentary mares resulted in no effect on dominance hierarchies, body mass or condition score. |
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| Address | Faculty of Veterinary Science, University of Sydney, Private Mailbag 4, Narellan Delivery Centre, Narellan, NSW 2567, Australia. davidh@camden.usyd.edu.au | ||||
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| Publisher | Place of Publication | Editor | |||
| Language | English | Summary Language  |
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| Series Volume | Series Issue | Edition | |||
| ISSN | 1090-0233 | ISBN | Medium | ||
| Area | Expedition | Conference | |||
| Notes | PMID:15683772 | Approved | no | ||
| Call Number | refbase @ user @ | Serial | 671 | ||
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| Author | Crosby, M.B.; Zhang, J.; Nowling, T.M.; Svenson, J.L.; Nicol, C.J.; Gonzalez, F.J.; Gilkeson, G.S. | ||||
| Title | Inflammatory modulation of PPAR gamma expression and activity | Type | Journal Article | ||
| Year | 2006 | Publication | Clinical immunology | Abbreviated Journal | Clin Immunol |
| Volume | 118 | Issue | 2-3 | Pages | 276-283 |
| Keywords | Age Factors; Animals; Cell Line, Transformed; Cells, Cultured; Female; Inflammation Mediators/*physiology; Kidney/metabolism; Mesangial Cells/metabolism; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred MRL lpr; Mice, Knockout; Nitric Oxide/biosynthesis; Nitric Oxide Synthase Type II/biosynthesis/genetics; PPAR gamma/*biosynthesis/*genetics/metabolism; Up-Regulation/immunology | ||||
| Abstract | Nitric oxide (NO) production increases with age in the lupus-prone MRL/lpr mouse, paralleling disease activity. One mechanism for excess NO production in MRL/lpr mice may be a defect in down-regulatory mechanisms of the iNOS pathway. A potential modulator of NO is the nuclear hormone receptor peroxisome proliferation activated receptor gamma (PPARgamma). We demonstrate that renal PPARgamma protein expression was altered as disease progressed in MRL/lpr mice, which paralleled increased iNOS protein expression. Additionally, MRL/lpr-derived primary mesangial cells expressed less PPARgamma than BALB/c mesangial cells and produced more NO in response to LPS and IFNgamma. Furthermore, PPARgamma activity was reduced in mesangial cells following exposure to inflammatory mediators. This activity was restored with the addition of a NOS enzyme inhibitor. These results indicate that the activation of inflammatory pathways may lead to reduced activity and expression of PPARgamma, further exacerbating the disease state. | ||||
| Address | Department of Medicine, Medical University of South Carolina, Charleston, SC 29425, USA | ||||
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| Publisher | Place of Publication | Editor | |||
| Language | English | Summary Language |
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| Series Volume | Series Issue | Edition | |||
| ISSN | 1521-6616 | ISBN | Medium | ||
| Area | Expedition | Conference | |||
| Notes | PMID:16303334 | Approved | no | ||
| Call Number | refbase @ user @ | Serial | 67 | ||
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| Author | Waters, A.J.; Nicol, C.J.; French, N.P. | ||||
| Title | Factors influencing the development of stereotypic and redirected behaviours in young horses: findings of a four year prospective epidemiological study | Type | Journal Article | ||
| Year | 2002 | Publication | Equine veterinary journal | Abbreviated Journal | Equine Vet J |
| Volume | 34 | Issue | 6 | Pages | 572-579 |
| Keywords | Age Factors; Animal Husbandry/*methods; Animal Welfare; Animals; *Behavior, Animal; Female; Horse Diseases/epidemiology/prevention & control/*psychology; Horses; Housing, Animal; Longitudinal Studies; Male; Prevalence; Prospective Studies; Risk Factors; *Stereotyped Behavior; Weaning | ||||
| Abstract | Stereotypies are invariant and repetitive behaviour patterns that seemingly have no function, which tend to develop in captive animals faced with insoluble problems and may be indicative of reduced welfare. A 4 year prospective study of the factors influencing the development of stereotypic and redirected behaviours (abnormal behaviour) in a population of 225 young Thoroughbred and part-Thoroughbred horses was conducted between 1995 and 1999. Abnormal behaviour affected 34.7% of the population. Multivariable analysis showed that foals of low- or middle-ranking mares were less likely to develop abnormal behaviour than foals of dominant mares (rate ratio (RR) 0.23, P<0.01; RR 0.48, P<0.01, respectively). Weaning by confinement in a stable or barn was associated with an increased rate of development of abnormal behaviour, compared with paddock-weaning (RR 2.19, P<0.05), and housing in barns, rather than at grass after weaning, was associated with a further increase (RR 2.54, P<0.01). Specific stereotypic and redirected behaviours were then considered as separate outcomes. Crib-biting was initiated by 10.5% of horses at median age 20 weeks, weaving by 4.6% of horses at median age 60 weeks, box-walking by 2.3% of horses at median age 64 weeks and wood-chewing by 30.3% of horses at median age 30 weeks. Wood-chewing developed at a lower rate in horses born to subordinate or mid-ranking mares than in horses born to dominant mares (RR 0.29, P<0.01; RR 0.41, P<0.01, respectively), and at a higher rate in horses kept in barns or stables rather than at grass after weaning (RR 4.49, P<0.001; RR 1A6, P<0.001, respectively). Feeding concentrates after weaning was associated with a 4-fold increase in the rate of development of crib-biting (RR 4.12, P = 0.02). The results of this study support the idea that simple changes in feeding, housing and weaning practices could substantially lower the incidence of abnormal behaviour in young horses. | ||||
| Address | University of Bristol, Department of Clinical Veterinary Science, Langford, Bristol, UK | ||||
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| Publisher | Place of Publication | Editor | |||
| Language | English | Summary Language |
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| Series Volume | Series Issue | Edition | |||
| ISSN | 0425-1644 | ISBN | Medium | ||
| Area | Expedition | Conference | |||
| Notes | PMID:12357996 | Approved | no | ||
| Call Number | refbase @ user @ | Serial | 84 | ||
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| Author | Schwarzenberger, F.; Mostl, E.; Bamberg, E.; Pammer, J.; Schmehlik, O. | ||||
| Title | Concentrations of progestagens and oestrogens in the faeces of pregnant Lipizzan, trotter and thoroughbred mares | Type | Journal Article | ||
| Year | 1991 | Publication | Journal of reproduction and fertility. Supplement | Abbreviated Journal | J Reprod Fertil Suppl |
| Volume | 44 | Issue | Pages | 489-499 | |
| Keywords | Animals; Estrogens/*analysis; Feces/*chemistry; Female; Gestational Age; Horses/*metabolism; Immunoenzyme Techniques; Labor, Obstetric; Pregnancy; Pregnancy, Animal/*metabolism; Pregnenes/analysis; Progestins/*analysis | ||||
| Abstract | Faecal samples were collected at weekly intervals from pregnant Lipizzan mares during Weeks 7-16 following mating and from Lipizzan, Trotter and Thoroughbred mares during the last 3 months of gestation. After parturition, samples were taken daily from the Thoroughbred mares for another 6 days. Non-pregnant mares served as controls. The concentrations of unconjugated oestrogens (Eg), 20 alpha-OH-progestagens (20 alpha-G) and 20 beta-OH-progestagens (20 beta-G) were measured by enzyme immunoassay. In the faeces of Lipizzan mares, immunoreactive progestagens were significantly (P less than 0.01) elevated above the levels in non-pregnant mares by Week 11, and Eg by Week 13 of pregnancy onwards. During the last 3 months of gestation, concentrations of Eg were significantly higher in Trotter mares than in Lipizzan and Thoroughbred mares. Concentrations of 20 alpha-G and 20 beta-G increased to maximal values in the last month of gestation. There was no significant difference among the 3 breeds with respect to 20 alpha-G but, during the 10 weeks before parturition, concentrations of 20 beta-G in the Lipizzan mares were significantly lower (P less than 0.05) than those in the Thoroughbred mares. They were also significantly lower than those of the Trotter mares during the last 4 weeks of gestation. After parturition, the concentrations of Eg and progestagens had declined to baseline values by Days 3 and 4 respectively. From these results we conclude that high concentrations of progestagens with 20 alpha- and 20 beta-hydroxyl groups are present in the faeces of pregnant mares, especially during the last month of gestation. | ||||
| Address | Institut fur Biochemie, Veterinary Medical University, Vienna, Austria | ||||
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| Publisher | Place of Publication | Editor | |||
| Language | English | Summary Language |
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| Series Editor | Series Title | Abbreviated Series Title | |||
| Series Volume | Series Issue | Edition | |||
| ISSN | 0449-3087 | ISBN | Medium | ||
| Area | Expedition | Conference | |||
| Notes | PMID:1795293 | Approved | no | ||
| Call Number | refbase @ user @ | Serial | 322 | ||
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| Author | Heitor, F.; do Mar Oom, M.; Vicente, L. | ||||
| Title | Social relationships in a herd of Sorraia horses Part I. Correlates of social dominance and contexts of aggression | Type | Journal Article | ||
| Year | 2006 | Publication | Behavioural Processes | Abbreviated Journal | Behav. Process. |
| Volume | 73 | Issue | 2 | Pages | 170-177 |
| Keywords | Age Factors; *Aggression; Animals; Female; *Hierarchy, Social; Horses/*psychology; Male; Sex Factors; *Social Dominance; *Social Environment; Statistics, Nonparametric | ||||
| Abstract | Factors related to dominance rank and the functions of aggression were studied in a herd of Sorraia horses, Equus caballus, under extensive management. Subjects were 10 adult mares 5-18 years old and a stallion introduced into the group for breeding. Dominance relationships among mares were clear, irrespective of rank difference, and remained stable after introduction of the stallion. The dominance hierarchy was significantly linear and rank was positively correlated with age and total aggressiveness. Higher-ranking mares received lower frequency and intensity of agonistic interactions. Nevertheless, higher-ranking dominants were not more likely to elicit submission from their subordinates than lower-ranking dominants. Neither close-ranking mares nor mares with less clear dominance relationships were more aggressive towards each other. Agonistic interactions seemed to be used more importantly in regulation of space than to obtain access to food or to reassert dominance relationships. Contexts of aggression were related to mare rank. The results suggest that dominance relationships based on age as a conventional criterion were established to reduce aggressiveness in a herd where the costs of aggression are likely to outweigh the benefits. | ||||
| Address | Centro de Biologia Ambiental, Faculdade de Ciencias da Universidade de Lisboa, Campo Grande, Edificio C2, 1749-016 Lisboa, Portugal | ||||
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| Language | English | Summary Language |
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| Series Volume | Series Issue | Edition | |||
| ISSN | 0376-6357 | ISBN | Medium | ||
| Area | Expedition | Conference | |||
| Notes | PMID:16815645 | Approved | no | ||
| Call Number | refbase @ user @ | Serial | 292 | ||
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| Author | Seyfarth, R.M.; Cheney, D.L.; Bergman, T.J. | ||||
| Title | Primate social cognition and the origins of language | Type | Journal Article | ||
| Year | 2005 | Publication | Trends in Cognitive Sciences | Abbreviated Journal | Trends. Cognit. Sci. |
| Volume | 9 | Issue | 6 | Pages | 264-266 |
| Keywords | Animals; *Cognition; Humans; *Language; Papio; Psychological Theory; Social Behavior; *Social Perception | ||||
| Abstract | Are the cognitive mechanisms underlying language unique, or can similar mechanisms be found in other domains? Recent field experiments demonstrate that baboons' knowledge of their companions' social relationships is based on discrete-valued traits (identity, rank, kinship) that are combined to create a representation of social relations that is hierarchically structured, open-ended, rule-governed, and independent of sensory modality. The mechanisms underlying language might have evolved from the social knowledge of our pre-linguistic primate ancestors. | ||||
| Address | Departments of Biology and Psychology, University of Pennsylvania, Philadelphia, PA 19104, USA. seyfarth@psych.upenn.edu | ||||
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| Language | English | Summary Language |
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| Series Volume | Series Issue | Edition | |||
| ISSN | 1364-6613 | ISBN | Medium | ||
| Area | Expedition | Conference | |||
| Notes | PMID:15925802 | Approved | no | ||
| Call Number | refbase @ user @ | Serial | 343 | ||
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| Author | Gentner, T.Q.; Fenn, K.M.; Margoliash, D.; Nusbaum, H.C. | ||||
| Title | Recursive syntactic pattern learning by songbirds | Type | Journal Article | ||
| Year | 2006 | Publication | Nature | Abbreviated Journal | Nature |
| Volume | 440 | Issue | 7088 | Pages | 1204-1207 |
| Keywords | Acoustic Stimulation; *Animal Communication; Animals; Auditory Perception/*physiology; Humans; *Language; Learning/*physiology; Linguistics; Models, Neurological; Semantics; Starlings/*physiology; Stochastic Processes | ||||
| Abstract | Humans regularly produce new utterances that are understood by other members of the same language community. Linguistic theories account for this ability through the use of syntactic rules (or generative grammars) that describe the acceptable structure of utterances. The recursive, hierarchical embedding of language units (for example, words or phrases within shorter sentences) that is part of the ability to construct new utterances minimally requires a 'context-free' grammar that is more complex than the 'finite-state' grammars thought sufficient to specify the structure of all non-human communication signals. Recent hypotheses make the central claim that the capacity for syntactic recursion forms the computational core of a uniquely human language faculty. Here we show that European starlings (Sturnus vulgaris) accurately recognize acoustic patterns defined by a recursive, self-embedding, context-free grammar. They are also able to classify new patterns defined by the grammar and reliably exclude agrammatical patterns. Thus, the capacity to classify sequences from recursive, centre-embedded grammars is not uniquely human. This finding opens a new range of complex syntactic processing mechanisms to physiological investigation. | ||||
| Address | Department of Organismal Biology and Anatomy, University of Chicago, Chicago, Illinois 60637, USA. tgentner@ucsd.edu | ||||
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| Language | English | Summary Language |
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| Series Volume | Series Issue | Edition | |||
| ISSN | 1476-4687 | ISBN | Medium | ||
| Area | Expedition | Conference | |||
| Notes | PMID:16641998 | Approved | no | ||
| Call Number | refbase @ user @ | Serial | 353 | ||
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| Author | Cameron, E.Z. | ||||
| Title | Facultative adjustment of mammalian sex ratios in support of the Trivers-Willard hypothesis: evidence for a mechanism | Type | Journal Article | ||
| Year | 2004 | Publication | Proceedings. Biological sciences / The Royal Society | Abbreviated Journal | Proc Biol Sci |
| Volume | 271 | Issue | 1549 | Pages | 1723-1728 |
| Keywords | Age Factors; Animals; Body Constitution; *Evolution; Female; Glucose/metabolism/physiology; Litter Size; Male; Mammals/*physiology; *Models, Biological; Reproduction/physiology; Seasons; Sex Factors; *Sex Ratio; Time Factors | ||||
| Abstract | Evolutionary theory predicts that mothers of different condition should adjust the birth sex ratio of their offspring in relation to future reproductive benefits. Published studies addressing variation in mammalian sex ratios have produced surprisingly contradictory results. Explaining the source of such variation has been a challenge for sex-ratio theory, not least because no mechanism for sex-ratio adjustment is known. I conducted a meta-analysis of previous mammalian sex-ratio studies to determine if there are any overall patterns in sex-ratio variation. The contradictory nature of previous results was confirmed. However, studies that investigated indices of condition around conception show almost unanimous support for the prediction that mothers in good condition bias their litters towards sons. Recent research on the role of glucose in reproductive functioning have shown that excess glucose favours the development of male blastocysts, providing a potential mechanism for sex-ratio variation in relation to maternal condition around conception. Furthermore, many of the conflicting results from studies on sex-ratio adjustment would be explained if glucose levels in utero during early cell division contributed to the determination of offspring sex ratios. | ||||
| Address | Mammal Research Institute, Department of Zoology and Entomology, University of Pretoria, Pretoria 0002, South Africa. ezcameron@zoology.up.ac.za | ||||
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| Language | English | Summary Language |
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| ISSN | 0962-8452 | ISBN | Medium | ||
| Area | Expedition | Conference | |||
| Notes | PMID:15306293 | Approved | no | ||
| Call Number | refbase @ user @ | Serial | 413 | ||
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| Author | Huebener, E. | ||||
| Title | Movements of Trunk and Back of the Horse from a Rider's View | Type | Journal Article | ||
| Year | 2004 | Publication | Tierärztliche Umschau | Abbreviated Journal | Tierärztl. Umschau |
| Volume | 6 | Issue | Pages | 327 | |
| Keywords | walk – trot – canter – pain – damages | ||||
| Abstract | The trunk and back movements of the horse during locomotion determine seat position and leg aids of the rider, this is the basis for horse-oriented and cultivated, sensitive riding. In their tendency these movements could now be derived from the foot sequences of the basic paces. The realizations are verified by video. By translating these movements into diagrams, the author is making an attempt to present the current state of knowledge for non-riding scholars and academically oriented riders alike. The acceptance of the prepared riding knowledge would be improved if one could produce measured values of the horse's back and trunk movements. An appeal of a rider for relevant, scholarly research. | ||||
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| Language | German | Summary Language |
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| Notes | Approved | no | |||
| Call Number | refbase @ user @ | Serial | 437 | ||
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| Author | Hemelrijk,C. K.; Wantia,J.; Gygax,L. | ||||
| Title | The construction of dominance order: comparing performance of five methods using an individual-based model | Type | Journal Article | ||
| Year | 2005 | Publication | Behaviour | Abbreviated Journal | Behaviour |
| Volume | 142 | Issue | 8 | Pages | 1043-1064 |
| Keywords | dominance order, ranking method, agent-based model, statistical method, aggression | ||||
| Abstract | In studies of animal behaviour investigators correlate dominance with all kinds of behavioural variables, such as reproductive success and foraging success. Many methods are used to produce a dominance hierarchy from a matrix reflecting the frequency of winning dominance interactions. These different methods produce different hierarchies. However, it is difficult to decide which ranking method is best. In this paper, we offer a new procedure for this decision: we use an individual-based model, called DomWorld, as a test-environment. We choose this model, because it provides access to both the internal dominance values of artificial agents (which reflects their fighting power) and the matrix of winning and losing among them and, in addition, because its behavioural rules are biologically inspired and its group-level patterns resemble those of real primates. We compare statistically the dominance hierarchy based on the internal dominance values of the artificial agents with the dominance hierarchy produced by ranking individuals by (a) their total frequency of winning, (b) their average dominance index, (c) a refined dominance index, the David`s score, (d) the number of subordinates each individual has and (e) a ranking method based on maximizing the linear order of the hierarchy. Because dominance hierarchies may differ depending on group size, type of society, and the interval of study, we compare these ranking methods for these conditions.We study complete samples as well as samples randomly chosen to resemble the limitations of observing real animals. It appears that two methods of medium complexity (the average dominance index and David`s score) lead to hierarchical orders that come closest to the hierarchy based on internal dominance values of the agents. We advocate usage of the average dominance index, because of its computational simplicity. |
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| Call Number | refbase @ user @ | Serial | 445 | ||
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