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Author Domjan, M. openurl 
  Title Selective suppression of drinking during a limited period following aversive drug treatment in rats Type Journal Article
  Year 1977 Publication Journal of Experimental Psychology. Animal Behavior Processes Abbreviated Journal J Exp Psychol Anim Behav Process  
  Volume 3 Issue 1 Pages 66-76  
  Keywords Animals; *Avoidance Learning; Awareness; Conditioning, Operant; Dose-Response Relationship, Drug; Drinking Behavior/*drug effects; Lithium/*poisoning; Male; Osmolar Concentration; Rats; Saccharin/administration & dosage; *Taste; Time Factors  
  Abstract Administration of lithium chloride disrupted the intake of flavored solutions but not water in rats. This intake suppression was directly related to the amount of lithium administered (Experiment 1), occurred with both palatable and unpalatable novel saccharin solutions (Experiment 2), but was only observed if subjects were tested starting less than 75 min. after lithium treatment (Experiment 3). Twenty-five daily exposures to saccharin did not attenuate the effect (Experiment 4). However, in saccharin-reared and vinegar-reared rats, lithium did not disrupt consumption of the solutions these subjects had access to throughout life, even though suppressions of intake were observed when these subjects were tested with novel flavors (Experiment 5). The selective disruption of drinking is interpreted as a novelty-dependent sensitization reaction to the discomfort of aversive drug administration.  
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  Language English Summary Language Original Title  
  Series Editor (down) Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0097-7403 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:845544 Approved no  
  Call Number Equine Behaviour @ team @ Serial 2788  
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Author Rudy, J.W.; Iwens, J.; Best, P.J. openurl 
  Title Pairing novel exteroceptive cues and illness reduces illness-induced taste aversions Type Journal Article
  Year 1977 Publication Journal of Experimental Psychology. Animal Behavior Processes Abbreviated Journal J Exp Psychol Anim Behav Process  
  Volume 3 Issue 1 Pages 14-25  
  Keywords Animals; *Association; *Avoidance Learning; Awareness; Conditioning, Operant; *Cues; Drinking Behavior; Environment; Inhibition (Psychology); Lithium/poisoning; Male; Rats; Saccharin/pharmacology; *Taste  
  Abstract Four experiments are reported that lead to the conclusion that pairing novel exteroceptive stimulation (placement into a black compartment) with a poison (lithium chloride) attenuates the development of an aversion to a taste (saccharin) subsequently paired with the poison. Such an attenuation effect occurs whether the exteroceptive cues are present or absent when the taste-poison pairing is administered. Interpretation and implications of this finding are discussed.  
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  Corporate Author Thesis  
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  Language English Summary Language Original Title  
  Series Editor (down) Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0097-7403 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:845542 Approved no  
  Call Number Equine Behaviour @ team @ Serial 2789  
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Author Mitchell, D.; Kirschbaum, E.H.; Perry, R.L. openurl 
  Title Effects of neophobia and habituation on the poison-induced avoidance of exteroceptive stimuli in the rat Type Journal Article
  Year 1975 Publication Journal of Experimental Psychology. Animal Behavior Processes Abbreviated Journal J Exp Psychol Anim Behav Process  
  Volume 1 Issue 1 Pages 47-55  
  Keywords Animals; Avoidance Learning/*drug effects; *Awareness; *Cognition; Conditioning, Operant; Feeding Behavior/drug effects; *Habituation, Psychophysiologic; Injections, Intraperitoneal; Lithium/administration & dosage/poisoning; Male; Rats; *Taste; Time Factors; *Visual Perception  
  Abstract Two experiments on the role of neophobia in poison-induced aversions to exteroceptive stimuli are reported. In Experiment 1, rats were given either 10 or 25 days of habituation to the test situation prior to conditioning. Those animals with the longer habituation period avoided a complex of novel exteroceptive stimuli while those with the shorter habituation period did not. In Experiment 2 rats initially avoided the more novel of two containers, but gradually came to eat equal amounts from both. A single pairing of toxicosis with consumption from either the novel or the familiar container reinstated the avoidance of the novel container in both cases. The results were discussed in terms of an interaction between habituation and conditioning procedures. It was suggested that previously reported differences between interoceptive and exteroceptive conditioning effects may have been influenced by the differential novelty of the two classes of stimuli in the test situation. It was further suggested that non-contingently poisoned control groups should routinely be included in poison avoidance conditioning studies.  
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  Language English Summary Language Original Title  
  Series Editor (down) Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0097-7403 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:1151289 Approved no  
  Call Number Equine Behaviour @ team @ Serial 2791  
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Author Blokland, A. openurl 
  Title Reaction time responding in rats Type Journal Article
  Year 1998 Publication Neuroscience and Biobehavioral Reviews Abbreviated Journal Neurosci Biobehav Rev  
  Volume 22 Issue 6 Pages 847-864  
  Keywords Amphetamine/pharmacology; Animals; Behavior, Animal/drug effects/*physiology; Conditioning, Operant/drug effects/*physiology; Dopamine Uptake Inhibitors/pharmacology; Dose-Response Relationship, Drug; Male; Rats; Rats, Inbred Lew; Reaction Time/drug effects/*physiology  
  Abstract The use of reaction time has a great tradition in the field of human information processing research. In animal research the use of reaction time test paradigms is mainly limited to two research fields: the role of the striatum in movement initiation; and aging. It was discussed that reaction time responding can be regarded as “single behavior”, this term was used to indicate that only one behavioral category is measured, allowing a better analysis of brain-behavior relationships. Reaction time studies investigating the role of the striatum in motor functions revealed that the initiation of a behavioral response is dependent on the interaction of different neurotransmitters (viz. dopamine, glutamate, GABA). Studies in which lesions were made in different brain structures suggested that motor initiation is dependent on defined brain structures (e.g. medialldorsal striatum, prefrontal cortex). It was concluded that the use of reaction time measures can indeed be a powerful tool in studying brain-behavior relationships. However, there are some methodological constraints with respect to the assessment of reaction time in rats, as was tried to exemplify by the experiments described in the present paper. On the one hand one should try to control for behavioral characteristics of rats that may affect the validity of the parameter reaction time. On the other hand, the mean value of reaction time should be in the range of what has been reported in man. Although these criteria were not always met in several studies, it was concluded that reaction time can be validly assessed in rats. Finally, it was discussed that the use of reaction time may go beyond studies that investigate the role of the basal ganglia in motor output. Since response latency is a direct measure of information processing this parameter may provide insight into basic elements of cognition. Based on the significance of reaction times in human studies the use of this dependent variable in rats may provide a fruitful approach in studying brain-behavior relationships in cognitive functions.  
  Address Department of Psychology, University of Maastricht, The Netherlands  
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  Language English Summary Language Original Title  
  Series Editor (down) Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0149-7634 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:9809315 Approved no  
  Call Number Equine Behaviour @ team @ Serial 2807  
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Author McKinley, S.; Young, R.J. url  openurl
  Title The efficacy of the model-rival method when compared with operant conditioning for training domestic dogs to perform a retrieval-selection task Type Journal Article
  Year 2003 Publication Applied Animal Behaviour Science Abbreviated Journal Appl. Anim. Behav. Sci.  
  Volume 81 Issue 4 Pages 357-365  
  Keywords Dogs; Learning; Operant conditioning; Model-rival; Cognition  
  Abstract Traditionally, dogs have been trained by operant conditioning techniques; that is, dogs make a desired behavioural response and this response is reinforced by a reward such as food. This type of training is very effective in training dogs to perform basic obedience behaviours (e.g. `stay'). However, dogs are social animals and should be predisposed to learn from social stimuli. In the present study, we used a modified version of the model-rival technique that has been extensively used in experiments investigating the cognitive ability of parrots. In this technique, social stimuli are used to create in the animal an interest in the object without the use of food or other rewards. Therefore, the animal learns the name of the object (intrinsic reward) and not that the object's name means food. In this experiment we compared the learning ability of nine pet dogs to solve the same retrieval-selection task having been previously trained using operant conditioning or model-rival techniques. The retrieval-selection task was the dogs had to correctly select the commanded object to bring to the experimenter from a group of three similar objects. The results show no difference in the speeds with which the dogs solved the test--demonstrating the efficacy of the model-rival method. This is the first time that the effectiveness of the model-rival technique has been experimentally demonstrated with dogs. Furthermore, we believe that the methodology reported in this paper has applications in dog training and in experiments into dog cognition.  
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  Notes Approved no  
  Call Number Equine Behaviour @ team @ Serial 2900  
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Author Grandin, T. openurl 
  Title Safe handling of large animals Type Journal Article
  Year 1999 Publication Occupational Medicine (Philadelphia, Pa.) Abbreviated Journal Occup Med  
  Volume 14 Issue 2 Pages 195-212  
  Keywords Accidents, Occupational/*prevention & control/statistics & numerical data; Aggression/physiology/psychology; Animal Husbandry/*methods; Animals; *Behavior, Animal/physiology; Cattle; Conditioning, Operant/physiology; Crowding/psychology; Fear/physiology/psychology; Female; *Horses/physiology/psychology; Humans; Male; Movement/physiology; *Occupational Health; Risk Factors; *Ruminants/physiology/psychology  
  Abstract The major causes of accidents with cattle, horses, and other grazing animals are: panic due to fear, male dominance aggression, or the maternal aggression of a mother protecting her newborn. Danger is inherent when handling large animals. Understanding their behavior patterns improves safety, but working with animals will never be completely safe. Calm, quiet handling and non-slip flooring are beneficial. Rough handling and excessive use of electric prods increase chances of injury to both people and animals, because fearful animals may jump, kick, or rear. Training animals to voluntarily cooperate with veterinary procedures reduces stress and improves safety. Grazing animals have a herd instinct, and a lone, isolated animal can become agitated. Providing a companion animal helps keep an animal calm.  
  Address Department of Animal Science, Colorado State University, Fort Collins 80526, USA  
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  ISSN 0885-114X ISBN Medium  
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  Notes PMID:10329901 Approved no  
  Call Number Equine Behaviour @ team @ Serial 3793  
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Author Matzke, S.M.; Oubre, J.L.; Caranto, G.R.; Gentry, M.K.; Galbicka, G. openurl 
  Title Behavioral and immunological effects of exogenous butyrylcholinesterase in rhesus monkeys Type Journal Article
  Year 1999 Publication Pharmacology, Biochemistry, and Behavior Abbreviated Journal Pharmacol Biochem Behav  
  Volume 62 Issue 3 Pages 523-530  
  Keywords Animals; Antibody Formation/drug effects; Behavior, Animal/*drug effects; Butyrylcholinesterase/*immunology/pharmacokinetics/*pharmacology; Cognition/drug effects; Color Perception/drug effects; Conditioning, Operant/drug effects; Discrimination Learning/drug effects; Half-Life; Horses; Humans; Macaca mulatta; Male  
  Abstract Although conventional therapies prevent organophosphate (OP) lethality, laboratory animals exposed to such treatments typically display behavioral incapacitation. Pretreatment with purified exogenous human or equine serum butyrylcholinesterase (Eq-BuChE), conversely, has effectively prevented OP lethality in rats and rhesus monkeys, without producing the adverse side effects associated with conventional treatments. In monkeys, however, using a commercial preparation of Eq-BuChE has been reported to incapacitate responding. In the present study, repeated administration of commercially prepared Eq-BuChE had no systematic effect on behavior in rhesus monkeys as measured by a six-item serial probe recognition task, despite 7- to 18-fold increases in baseline BuChE levels in blood. Antibody production induced by the enzyme was slight after the first injection and more pronounced following the second injection. The lack of behavioral effects, the relatively long in vivo half-life, and the previously demonstrated efficacy of BuChE as a biological scavenger for highly toxic OPs make BuChE potentially more effective than current treatment regimens for OP toxicity.  
  Address Walter Reed Army Institute of Research, Washington, DC 20307-5100, USA  
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  Series Volume Series Issue Edition  
  ISSN 0091-3057 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:10080246 Approved no  
  Call Number Equine Behaviour @ team @ Serial 4064  
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Author Neuringer, A. doi  openurl
  Title Reinforced variability in animals and people: implications for adaptive action Type Journal Article
  Year 2004 Publication The American Psychologist Abbreviated Journal Am Psychol  
  Volume 59 Issue 9 Pages 891-906  
  Keywords Animals; Behavior, Animal; *Choice Behavior; Conditioning, Operant; Creativeness; Discrimination (Psychology); Humans; Memory; Problem Solving; *Reinforcement (Psychology)  
  Abstract Although reinforcement often leads to repetitive, even stereotyped responding, that is not a necessary outcome. When it depends on variations, reinforcement results in responding that is diverse, novel, indeed unpredictable, with distributions sometimes approaching those of a random process. This article reviews evidence for the powerful and precise control by reinforcement over behavioral variability, evidence obtained from human and animal-model studies, and implications of such control. For example, reinforcement of variability facilitates learning of complex new responses, aids problem solving, and may contribute to creativity. Depression and autism are characterized by abnormally repetitive behaviors, but individuals afflicted with such psychopathologies can learn to vary their behaviors when reinforced for so doing. And reinforced variability may help to solve a basic puzzle concerning the nature of voluntary action.  
  Address Department of Psychology, Reed College, Portland, OR 97202, USA. allen.neuringer@reed.edu  
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  Language English Summary Language Original Title  
  Series Editor (down) Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0003-066X ISBN Medium  
  Area Expedition Conference  
  Notes PMID:15584823 Approved no  
  Call Number Equine Behaviour @ team @ Serial 4106  
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