| Records |
| Author |
Houpt, K.A.; Northrup, N.; Wheatley, T.; Houpt, T.R. |
| Title |
Thirst and salt appetite in horses treated with furosemide |
Type |
Journal Article |
| Year |
1991 |
Publication |
Journal of applied physiology (Bethesda, Md. : 1985) |
Abbreviated Journal |
J Appl Physiol |
| Volume |
71 |
Issue |
6 |
Pages |
2380-2386 |
| Keywords |
Animals; Appetite/*drug effects; Blood Volume; Diuresis; Drinking/drug effects; Female; Furosemide/*pharmacology; Horses; Natriuresis; Sodium, Dietary/*administration & dosage; Thirst/*drug effects |
| Abstract |
When a preliminary experiment in sodium-replete ponies revealed an increase, but not a significant increase, in salt consumption after furosemide treatment, the experiment was repeated using sodium-deficient horses in which aldosterone levels might be expected to be elevated to test the hypothesis that a background of aldosterone is necessary for salt appetite. Ten Standardbred mares were injected intravenously with furosemide or an equivalent volume of 0.9% sodium chloride as a control to test the effect of furosemide on their salt appetite and blood constituents. Sodium intake and sodium loss in urine, as well as water intake and urine output, were measured and compared to determine accuracy of compensation for natriuresis and diuresis. Plasma protein and packed cell volume showed significant increases in response to furosemide treatment (F = 29.31, P less than 0.001 and F = 11.20, P less than 0.001, respectively). There were no significant changes in plasma sodium concentration or osmolality in response to the treatment (P greater than 0.05). The furosemide-treated horses consumed 126 +/- 14.8 g salt, significantly more than when they were given the control injection (94.5 +/- 9.8 g; t = 2.22, P = 0.05). In response to furosemide, horses lost 962 +/- 79.7 and consumed 2,170 +/- 5 meq sodium; however, compared with control, they lost 955 meq more sodium and ingested only 570 meq more sodium, so they were undercompensating for natriuresis. The furosemide-treated horses drank 9.6 +/- 0.8 kg of water, significantly more than when they received the control injection (6.4 +/- 0.8 kg; t = 6.9, P less than 0.001).(ABSTRACT TRUNCATED AT 250 WORDS) |
| Address |
Department of Physiology, College of Veterinary Medicine, Cornell University, Ithaca, New York 14853-6401 |
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English |
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Edition |
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| ISSN |
8750-7587 |
ISBN |
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| Notes |
PMID:1778936 |
Approved |
no |
| Call Number |
refbase @ user @ |
Serial  |
38 |
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| Author |
Stahlbaum, C.C.; Houpt, K.A. |
| Title |
The role of the Flehmen response in the behavioral repertoire of the stallion |
Type |
Journal Article |
| Year |
1989 |
Publication |
Physiology & behavior |
Abbreviated Journal |
Physiol. Behav. |
| Volume |
45 |
Issue |
6 |
Pages |
1207-1214 |
| Keywords |
Animals; Behavior, Animal/*physiology; Circadian Rhythm; Discrimination (Psychology)/physiology; Estrus; Feces; Female; Horses/*physiology; Male; Sexual Behavior, Animal/*physiology; Smell/*physiology; Taste/physiology; Urine |
| Abstract |
The role of the Flehmen response in equine behavior was investigated under field and laboratory conditions. In Experiment 1, a field study made of five stallions on pasture with between three and eighteen mares each during the season indicated the following: 1) The Flehmen response was most frequently preceded by nasal, rather than oral, investigation of substances; 2) The stallions' rate of Flehmen varied with the estrous cycles of the mares; 3) The rate of Flehmen response did not show a variation with time of day; and 4) The Flehmen response was most frequently followed by marking behaviors rather than courtship behaviors. The results suggest that the Flehmen response is not an immediate component of sexual behavior, e.g., courtship of the stallion but may be involved in the overall monitoring of the mare's estrous cycle. Therefore the Flehmen response may contribute to the chemosensory priming of the stallion for reproduction. In Experiment 2 stallions were presented with urine or feces of mares in various stages of the reproductive cycle as well as with their own or other males' urine or feces. The occurrence of sniffing and Flehmen was used to determine the discriminatory ability of the stallions. Stallions can differentiate the sex of a horse on the basis of its feces alone, but cannot differentiate on the basis of urine. This ability may explain the function of fecal marking behavior of stallions. |
| Address |
New York State College of Veterinary Medicine, Cornell University, Ithaca 14853 |
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English |
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Edition |
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| ISSN |
0031-9384 |
ISBN |
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| Notes |
PMID:2813545 |
Approved |
no |
| Call Number |
refbase @ user @ |
Serial |
44 |
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| Author |
Houpt, K.A.; Thornton, S.N.; Allen, W.R. |
| Title |
Vasopressin in dehydrated and rehydrated ponies |
Type |
Journal Article |
| Year |
1989 |
Publication |
Physiology & behavior |
Abbreviated Journal |
Physiol. Behav. |
| Volume |
45 |
Issue |
3 |
Pages |
659-661 |
| Keywords |
Animals; Behavior, Animal/*physiology; Dehydration/*blood; Drinking Behavior/*physiology; Female; Horses/*blood; Osmolar Concentration; Reaction Time; Time Factors; Vasopressins/*blood |
| Abstract |
Six pony mares deprived of water for 24 hours showed significant increases in plasma vasopressin (2.8 pg/ml) and osmolality (9 mosmol/kg). When water was made available the ponies drank rapidly (5 of 6 drank to satiety within 90 seconds) and corrected their fluid deficits precisely. Vasopressin did not return to predehydration levels until osmolality did after 15 minutes of access to water. The horse differs from rodents and humans, but is similar to pigs in that vasopressin levels do not fall before osmolality returns to normal. Oropharyngeal factors, therefore, may not be as important in vasopressin release in horses as in other species. |
| Address |
New York State College of Veterinary Medicine, Cornell University, Ithaca 14853-6401 |
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English |
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| ISSN |
0031-9384 |
ISBN |
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Conference |
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| Notes |
PMID:2756059 |
Approved |
no |
| Call Number |
refbase @ user @ |
Serial |
45 |
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| Author |
Houpt, K.A.; Perry, P.J.; Hintz, H.F.; Houpt, T.R. |
| Title |
Effect of meal frequency on fluid balance and behavior of ponies |
Type |
Journal Article |
| Year |
1988 |
Publication |
Physiology & behavior |
Abbreviated Journal |
Physiol. Behav. |
| Volume |
42 |
Issue |
5 |
Pages |
401-407 |
| Keywords |
Animals; Behavior, Animal/*physiology; Blood Proteins/analysis; *Eating; Female; Hematocrit; Horses/blood/*physiology; Osmolar Concentration; *Water-Electrolyte Balance |
| Abstract |
Twelve ponies were fed their total daily ration either as one large meal or divided into six small meals. Pre- and post-feeding behavior was recorded six times a day. Blood samples were taken for 30 min before and two hr after the meal. Plasma protein increased from 7.0 to a peak of 7.3 g/dl with small meals and from 7.3 to 8.1 g/dl with large meals, and returned to pre-feeding levels by 90 min post-feeding. Hematocrit rose from 33.3 to 34.1% with small meals and from 33.0 to 36.0% with large meals. These rapid and short-lived increases indicate a decrease in plasma volume. Plasma osmolality rose with feeding from 283 to 285 mosmoles/kg with small meals and from 281 to 288 mosmoles/kg with large meals. Water availability had no significant effect on blood changes. Digestibility and rate of passage were measured with chromic oxide, but there were no differences. Vocalizing (neighing) and walking occurred more often before than after feeding, while eating bedding and engaging in other oral behaviors were more frequent after feeding. |
| Address |
Department of Physiology, New York State College of Veterinary Medicine, Cornell University, Ithaca 14853 |
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English |
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Edition |
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| ISSN |
0031-9384 |
ISBN |
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Medium |
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Expedition |
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Conference |
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| Notes |
PMID:3393599 |
Approved |
no |
| Call Number |
refbase @ user @ |
Serial |
47 |
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| Author |
Laut, J.E.; Houpt, K.A.; Hintz, H.F.; Houpt, T.R. |
| Title |
The effects of caloric dilution on meal patterns and food intake of ponies |
Type |
Journal Article |
| Year |
1985 |
Publication |
Physiology & behavior |
Abbreviated Journal |
Physiol. Behav. |
| Volume |
35 |
Issue |
4 |
Pages |
549-554 |
| Keywords |
Animals; Body Weight; *Diet; Energy Intake; *Feeding Behavior; Homeostasis; Horses/*physiology; Male |
| Abstract |
In order to determine if horses will increase their intake in response to caloric dilution, four pony geldings were fed ad lib a mixed grain diet either undiluted (3.4 Mcal/kg of digestible energy) or diluted (wt/wt) with 25% sawdust (2.6 Mcal/kg) or with 50% sawdust (1.7 Mcal/kg). The mean daily caloric intake was 17,457 kcal (3.4 Mcal diet), 17,546 kcal (2.6 Mcal diet) and 12,844 kcal (1.7 Mcal). The mean time spent eating was 246 (3.4 Mcal), 351 (2.6 Mcal), and 408 (1.7 Mcal) minutes/day. Meal size increased and meal frequency decreased with increasing dilution. The median long survivorships of intermeal intervals were 6.4 min (3.4 Mcal), 3.95 min (2.6 Mcal) and 4.91 min (1.7 Mcal). Ponies responded to caloric dilution by increasing the volume of intake to maintain caloric intake when the diet had 25% diluent. When the diet was diluted by 50%, intake was increased, but not at a rate adequate to maintain caloric intake. However, the ponies were able to maintain body weight. |
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English |
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0031-9384 |
ISBN |
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Conference |
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| Notes |
PMID:4070429 |
Approved |
no |
| Call Number |
refbase @ user @ |
Serial |
52 |
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| Author |
Williams, D.O.; Boatwright, R.B.; Rugh, K.S.; Garner, H.E.; Griggs, D.M.J. |
| Title |
Myocardial blood flow, metabolism, and function with repeated brief coronary occlusions in conscious ponies |
Type |
Journal Article |
| Year |
1991 |
Publication |
The American journal of physiology |
Abbreviated Journal |
Am J Physiol |
| Volume |
260 |
Issue |
1 Pt 2 |
Pages |
H100-9 |
| Keywords |
Animals; Consciousness/*physiology; Coronary Circulation/*physiology; Coronary Disease/pathology/*physiopathology; Disease Models, Animal; Hemodynamic Processes/physiology; Horses/*physiology; Hydrogen/metabolism; Lactates/metabolism; Myocardium/*metabolism/pathology; Norepinephrine/metabolism; Potassium/metabolism; Regional Blood Flow |
| Abstract |
Studies were performed in the conscious pony instrumented with a Doppler flow probe and hydraulic occluder on the left anterior descending coronary artery (LAD), sonomicrometry crystals and intraventricular micromanometer in the left ventricle, and catheters in the left atrium and anterior interventricular vein. Two-minute LAD occlusions were performed every 30 min continuously or during working hours. Data on release of catabolites (potassium, hydrogen ions, and lactate) and norepinephrine from the initially dysfunctional region were obtained periodically during a regimen of 445 +/- 56 occlusions in six animals. Regional myocardial blood flow was measured (microsphere method) before and after an occlusion regimen in four animals. Marked release of catabolites and norepinephrine from the initially dysfunctional region was noted in association with early occlusions when myocardial segment function was severely reduced. With further occlusions, release of these substances decreased while segment function improved. Blood flow was markedly decreased in the initially dysfunctional region during an early occlusion but was at the control level during a later occlusion. Although the metabolic findings are consistent with protection due to “ischemic preconditioning” and no increase in collateral perfusion, the inverse relationship noted between catabolite release and segment function is best explained by flow-dependent mechanisms. These results, together with the myocardial blood flow data, serve to validate a previous assumption that protection against regional myocardial dysfunction under these conditions is due to increased collateral perfusion. |
| Address |
Department of Physiology, University of Missouri, Columbia 65212 |
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English |
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Edition |
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| ISSN |
0002-9513 |
ISBN |
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Conference |
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| Notes |
PMID:1992786 |
Approved |
no |
| Call Number |
refbase @ user @ |
Serial |
98 |
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| Author |
Forster, H.V.; Pan, L.G.; Bisgard, G.E.; Flynn, C.; Hoffer, R.E. |
| Title |
Changes in breathing when switching from nares to tracheostomy breathing in awake ponies |
Type |
Journal Article |
| Year |
1985 |
Publication |
Journal of applied physiology (Bethesda, Md. : 1985) |
Abbreviated Journal |
J Appl Physiol |
| Volume |
59 |
Issue |
4 |
Pages |
1214-1221 |
| Keywords |
Airway Resistance; Animals; Chemoreceptors/physiology; Consciousness; Exertion; Horses/*physiology; Lung Compliance; Pulmonary Gas Exchange; Pulmonary Stretch Receptors/physiology; *Respiration; Respiratory Dead Space; *Tracheotomy |
| Abstract |
We assessed the consequences of respiratory unloading associated with tracheostomy breathing (TBr). Three normal and three carotid body-denervated (CBD) ponies were prepared with chronic tracheostomies that at rest reduced physiological dead space (VD) from 483 +/- 60 to 255 +/- 30 ml and lung resistance from 1.5 +/- 0.14 to 0.5 +/- 0.07 cmH2O . l-1 . s. At rest and during steady-state mild-to-heavy exercise arterial PCO2 (PaCO2) was approximately 1 Torr higher during nares breathing (NBr) than during TBr. Pulmonary ventilation and tidal volume (VT) were greater and alveolar ventilation was less during NBr than TBr. Breathing frequency (f) did not differ between NBr and TBr at rest, but f during exercise was greater during TBr than during NBr. These responses did not differ between normal and CBD ponies. We also assessed the consequences of increasing external VD (300 ml) and resistance (R, 0.3 cmH2O . l-1 . s) by breathing through a tube. At rest and during mild exercise tube breathing caused PaCO2 to transiently increase 2-3 Torr, but 3-5 min later PaCO2 usually was within 1 Torr of control. Tube breathing did not cause f to change. When external R was increased 1 cmH2O . l-1 . s by breathing through a conventional air collection system, f did not change at rest, but during exercise f was lower than during unencumbered breathing. These responses did not differ between normal, CBD, and hilar nerve-denervated ponies, and they did not differ when external VD or R were added at either the nares or tracheostomy.(ABSTRACT TRUNCATED AT 250 WORDS) |
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| ISSN |
8750-7587 |
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Conference |
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| Notes |
PMID:4055600 |
Approved |
no |
| Call Number |
refbase @ user @ |
Serial |
100 |
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| Author |
Alexander, F. |
| Title |
A study of parotid salivation in the horse |
Type |
Journal Article |
| Year |
1966 |
Publication |
The Journal of physiology |
Abbreviated Journal |
J Physiol |
| Volume |
184 |
Issue |
3 |
Pages |
646-656 |
| Keywords |
Animals; Atropine/*pharmacology; Bicarbonates/metabolism; Calcium/metabolism; Chlorides/metabolism; Horses; Mastication/*physiology; Parotid Gland/*physiology; Pilocarpine/*pharmacology; Potassium/metabolism; Salivation/*drug effects; Sodium/metabolism; Tetracaine/*pharmacology |
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0022-3751 |
ISBN |
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| Notes |
PMID:5963737 |
Approved |
no |
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refbase @ user @ |
Serial |
119 |
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| Author |
Alexander, F.; Ash, R.W. |
| Title |
The effect of emotion and hormones on the concentration of glucose and eosinophils in horse blood |
Type |
Journal Article |
| Year |
1955 |
Publication |
The Journal of physiology |
Abbreviated Journal |
J Physiol |
| Volume |
130 |
Issue |
3 |
Pages |
703-710 |
| Keywords |
Blood Glucose/*drug effects; Eosinophils/*drug effects; Leukocyte Count/*drug effects; *ACTH/effects; *BLOOD SUGAR/effect of drugs on; *EOSINOPHIL COUNT/effect of drugs on; *EPINEPHRINE/effects; *HISTAMINE/effects; *INSULIN/effects; *STRESS/experimental |
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0022-3751 |
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| Notes |
PMID:13278929 |
Approved |
no |
| Call Number |
refbase @ user @ |
Serial |
122 |
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| Author |
Alexander, F. |
| Title |
Factors affecting the blood sugar concentration in horses |
Type |
Journal Article |
| Year |
1955 |
Publication |
Quarterly journal of experimental physiology and cognate medical sciences |
Abbreviated Journal |
Q J Exp Physiol Cogn Med Sci |
| Volume |
40 |
Issue |
1 |
Pages |
24-31 |
| Keywords |
Blood Glucose/*analysis; *Horses; *BLOOD SUGAR/determination; *Horses |
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| ISSN |
0033-5541 |
ISBN |
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| Notes |
PMID:14371987 |
Approved |
no |
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refbase @ user @ |
Serial |
123 |
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