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Author | Alexander, F. | ||||
Title | The effect of diuretics on the faecal excretion of water and electrolytes in horses | Type | Journal Article | ||
Year | 1977 | Publication | British journal of pharmacology | Abbreviated Journal | Br J Pharmacol |
Volume | 60 | Issue | 4 | Pages | 589-593 |
Keywords | Animals; Body Water/*metabolism; Chlorides/metabolism; Electrolytes/*metabolism; Feces/*analysis; Furosemide/*pharmacology; Horses; Hydrochlorothiazide/*pharmacology; Male; Potassium/metabolism; Sodium/metabolism; Time Factors | ||||
Abstract | 1. The effect on plasma, urinary and faecal electrolytes of frusemide and hydrochlorthiazide was measured in ponies, mean weight 180 kg. 2. The rapid loss in urine of large quantities of sodium had only a small effect on plasma sodium concentration. 3. Faecal sodium excretion was increased substantially after the administration of frusemide. 4. Frusemide increased faecal potassium during the 48 h following administration and faecal water in the 24/48 h period. It also produced a hypopotassaemia. 5. Hydrochlorthiazide increased faecal chloride during the 24 h after administration. 6. Frusemide increased the intestinal transit time of both liquid (polyethylene glycol) and particulate (Cr2O3) markers. | ||||
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Corporate Author | Thesis | ||||
Publisher | Place of Publication | Editor | |||
Language | English | Summary Language | Original Title | ||
Series Editor | Series Title | Abbreviated Series Title | |||
Series Volume | Series Issue | Edition | |||
ISSN | 0007-1188 | ISBN | Medium | ||
Area | Expedition | Conference | |||
Notes | PMID:907872 | Approved | no | ||
Call Number | refbase @ user @ | Serial | 111 | ||
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