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Author Barrey, E.; Desliens, F.; Poirel, D.; Biau, S.; Lemaire, S.; Rivero, J.L.L.; Langlois, B.
Title Early evaluation of dressage ability in different breeds Type Journal Article
Year 2002 Publication (down) Equine Veterinary Journal. Supplement Abbreviated Journal Equine Vet J Suppl
Volume Issue 34 Pages 319-324
Keywords Animals; Biomechanics; Breeding; Discriminant Analysis; Female; Forelimb; Gait/genetics/*physiology; Hindlimb; Horses/anatomy & histology/*genetics/*physiology; Male; Photography/veterinary; *Physical Conditioning, Animal; Sports
Abstract Dressage is one of the Olympic equestrian sports practiced in several countries using different horse breeds. Specific characteristics of the walk, trot and canter are required for dressage. It has been assumed that some of these traits could be selected for genetically and contribute to dressage performance. The purpose of this study was to compare the walk, trot and conformation characteristics in young horses of different breeds used for dressage. A total of 142 horses age 3 years were classified into 3 groups of breeds (German, French and Spanish saddle horses) and tested using the same procedure. The skeletal conformation measurements were made by image analysis. Gait variables of the walk and trot were measured by the accelerometric gait analysis system Equimetrix. Discriminant analysis could explain the variability between the groups by taking into account the walk (P<0.0003), trot (P<0.0001) and conformation variables (P<0.0001). Many gait and conformation variables were significantly different between the breeds. In summary, the German horses had gait characteristics more adapted for dressage competition, and the results of this group could be used as a reference for early evaluation in dressage. Purebred Spanish horses could be considered as a reference for collected gaits used for farm work and old academic dressage. The gait and conformation tests could be applied in a breeding or crossing plan to detect more accurately young horses with good dressage ability.
Address INRA, Station de Genetique Quantitative et Appliquee, Groupe Cheval, Jouy-en-Josas, France
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Notes PMID:12405708 Approved no
Call Number Equine Behaviour @ team @ Serial 3726
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Author Edwards, D.H.; Spitzer, N.
Title 6. Social dominance and serotonin receptor genes in crayfish Type Journal Article
Year 2006 Publication (down) Current Topics in Developmental Biology Abbreviated Journal Curr Top Dev Biol
Volume 74 Issue Pages 177-199
Keywords Animals; Astacoidea/*genetics/physiology; Humans; Receptors, Serotonin/*genetics; Serotonin/physiology; *Social Dominance
Abstract Gene expression affects social behavior only through changes in the excitabilities of neural circuits that govern the release of the relevant motor programs. In turn, social behavior affects gene expression only through patterns of sensory stimulation that produce significant activation of relevant portions of the nervous system. In crayfish, social interactions between pairs of animals lead to changes in behavior that mark the formation of a dominance hierarchy. Those changes in behavior result from changes in the excitability of specific neural circuits. In the new subordinate, circuits for offensive behavior become less excitable and those for defensive behavior become more excitable. Serotonin, which is implicated in mechanisms for social dominance in many animals, modulates circuits for escape and avoidance responses in crayfish. The modulatory effects of serotonin on the escape circuits have been found to change with social dominance, becoming excitatory in dominant crayfish and inhibitory in subordinates. These changes in serotonin's effects on escape affect the synaptic response to sensory input of a single cell, the lateral giant (LG) command neuron for escape. Moreover, these changes occur over a 2-week period and for the subordinate are reversible at any time following a reversal of the animal's status. The results have suggested that a persistent change in social status leads to a gradual change in the expression of serotonin receptors to a pattern that is more appropriate for the new status. To test that hypothesis, the expression patterns of crayfish serotonin receptors must be compared in dominant and subordinate animals. Two of potentially five serotonin receptors in crayfish have been cloned, sequenced, and pharmacologically characterized. Measurements of receptor expression in the whole CNS of dominant and subordinate crayfish have produced inconclusive results, probably because each receptor is widespread in the nervous system and is likely to experience opposite expression changes in different areas of the CNS. Both receptors have recently been found in identified neurons that mediate escape responses, and so the next step will be to measure their expression in these identified cells in dominant and subordinate animals.
Address Department of Biology, Georgia State University, Atlanta, GA 30302, USA
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ISSN 0070-2153 ISBN Medium
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Notes PMID:16860668 Approved no
Call Number Equine Behaviour @ team @ Serial 4364
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Author Crosby, M.B.; Zhang, J.; Nowling, T.M.; Svenson, J.L.; Nicol, C.J.; Gonzalez, F.J.; Gilkeson, G.S.
Title Inflammatory modulation of PPAR gamma expression and activity Type Journal Article
Year 2006 Publication (down) Clinical immunology Abbreviated Journal Clin Immunol
Volume 118 Issue 2-3 Pages 276-283
Keywords Age Factors; Animals; Cell Line, Transformed; Cells, Cultured; Female; Inflammation Mediators/*physiology; Kidney/metabolism; Mesangial Cells/metabolism; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred MRL lpr; Mice, Knockout; Nitric Oxide/biosynthesis; Nitric Oxide Synthase Type II/biosynthesis/genetics; PPAR gamma/*biosynthesis/*genetics/metabolism; Up-Regulation/immunology
Abstract Nitric oxide (NO) production increases with age in the lupus-prone MRL/lpr mouse, paralleling disease activity. One mechanism for excess NO production in MRL/lpr mice may be a defect in down-regulatory mechanisms of the iNOS pathway. A potential modulator of NO is the nuclear hormone receptor peroxisome proliferation activated receptor gamma (PPARgamma). We demonstrate that renal PPARgamma protein expression was altered as disease progressed in MRL/lpr mice, which paralleled increased iNOS protein expression. Additionally, MRL/lpr-derived primary mesangial cells expressed less PPARgamma than BALB/c mesangial cells and produced more NO in response to LPS and IFNgamma. Furthermore, PPARgamma activity was reduced in mesangial cells following exposure to inflammatory mediators. This activity was restored with the addition of a NOS enzyme inhibitor. These results indicate that the activation of inflammatory pathways may lead to reduced activity and expression of PPARgamma, further exacerbating the disease state.
Address Department of Medicine, Medical University of South Carolina, Charleston, SC 29425, USA
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ISSN 1521-6616 ISBN Medium
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Notes PMID:16303334 Approved no
Call Number refbase @ user @ Serial 67
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Author McClearn, G.E.
Title Behavioral genetics Type Journal Article
Year 1971 Publication (down) Behavioral Science Abbreviated Journal Behav Sci
Volume 16 Issue 1 Pages 64-81
Keywords Amino Acid Metabolism, Inborn Errors; Animals; Aptitude; Behavior, Animal; Chromosome Aberrations; Cognition; Cytogenetics; Female; *Genetics, Behavioral; Genetics, Population; Humans; Intelligence; Mental Retardation; Mice; Models, Biological; Personality; Phenylketonurias; Pregnancy; Research; Schizophrenia; Sex Chromosome Aberrations; Twins
Abstract
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ISSN 0005-7940 ISBN Medium
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Notes PMID:5105941 Approved no
Call Number Equine Behaviour @ team @ Serial 4150
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Author Morley, K.I.; Montgomery, G.W.
Title The genetics of cognitive processes: candidate genes in humans and animals Type Journal Article
Year 2001 Publication (down) Behavior Genetics Abbreviated Journal Behav Genet
Volume 31 Issue 6 Pages 511-531
Keywords Animals; *Chromosome Mapping; Drosophila melanogaster; Genetic Markers/*genetics; Humans; Intelligence/*genetics; Mental Retardation/genetics; Mice; Phenotype; Quantitative Trait, Heritable
Abstract It has been hypothesized that numerous genes contribute to individual variation in human cognition. An extensive search of the scientific literature was undertaken to identify candidate genes which might contribute to this complex trait. A list of over 150 candidate genes that may influence some aspect of cognition was compiled. Some genes are particularly strong candidates based on evidence for involvement in cognitive processes in humans, mice, and Drosophila melanogaster. This survey confirms that many genes are associated with cognitive variation and highlights the potential importance of animal models in the study of human cognition.
Address Genetic Epidemiology Laboratory, Queensland Institute of Medical Research, Brisbane, Australia
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ISSN 0001-8244 ISBN Medium
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Notes PMID:11838530 Approved no
Call Number Equine Behaviour @ team @ Serial 4141
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Author Bouchard, T.J.J.; Loehlin, J.C.
Title Genes, evolution, and personality Type Journal Article
Year 2001 Publication (down) Behavior Genetics Abbreviated Journal Behav Genet
Volume 31 Issue 3 Pages 243-273
Keywords Animals; *Evolution; Genetics, Behavioral; Humans; Individuality; Personality/*genetics; Twin Studies
Abstract There is abundant evidence, some of it reviewed in this paper, that personality traits are substantially influenced by the genes. Much remains to be understood about how and why this is the case. We argue that placing the behavior genetics of personality in the context of epidemiology, evolutionary psychology, and neighboring psychological domains such as interests and attitudes should help lead to new insights. We suggest that important methodological advances, such as measuring traits from multiple viewpoints, using large samples, and analyzing data by modern multivariate techniques, have already led to major changes in our view of such perennial puzzles as the role of “unshared environment” in personality. In the long run, but not yet, approaches via molecular genetics and brain physiology may also make decisive contributions to understanding the heritability of personality traits. We conclude that the behavior genetics of personality is alive and flourishing but that there remains ample scope for new growth and that much social science research is seriously compromised if it does not incorporate genetic variation in its explanatory models.
Address Department of Psychology. University of Minnesota, Minneapolis 55455, USA. bouch001@tc.umn.edu
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ISSN 0001-8244 ISBN Medium
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Notes PMID:11699599 Approved no
Call Number Equine Behaviour @ team @ Serial 4142
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Author Weiss, A.; King, J.E.; Figueredo, A.J.
Title The heritability of personality factors in chimpanzees (Pan troglodytes) Type Journal Article
Year 2000 Publication (down) Behavior Genetics Abbreviated Journal Behav Genet
Volume 30 Issue 3 Pages 213-221
Keywords Animals; Female; Humans; Male; Models, Genetic; Pan troglodytes/*genetics; Personality/*genetics; Social Environment
Abstract Human personality and behavior genetic studies have resulted in a growing consensus that five heritable factors account for most variance in human personality. Prior research showed that chimpanzee personality is composed of a dominance-related factor and five human-like factors--Surgency, Dependability, Emotional Stability, Agreeableness, and Openness. Genetic, shared zoo, and nonshared environmental variance components of the six factors were estimated by regressing squared phenotypic differences of all possible pairs of chimpanzees onto 1 – Rij, where Rij equals the degree of relationship and a variable indicating whether the pair was housed in the same zoo. Dominance showed significant narrow-sense heritability. Shared zoo effects accounted for only a negligible proportion of the variance for all factors.
Address Department of Psychology, University of Arizona, Tucson 85721, USA. aweiss@u.arizona.edu
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ISSN 0001-8244 ISBN Medium
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Notes PMID:11105395 Approved no
Call Number Equine Behaviour @ team @ Serial 4143
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Author Boice, R.
Title Behavioral comparability of wild and domesticated rats Type Journal Article
Year 1981 Publication (down) Behavior Genetics Abbreviated Journal Behav Genet
Volume 11 Issue 5 Pages 545-553
Keywords Animals; *Behavior, Animal; Female; Genetics, Behavioral; Intelligence; Learning; Male; Rats/*genetics
Abstract The oft-repeated concern for the lack of behavioral comparability of domestic rats with wild forms of Rattus norvegicus is unfounded. Laboratory rats appear to show the potential for all wild-type behaviors, including the most dramatic social postures. Moreover, domestics are capable of assuming a feral existence without difficulty, one where they readily behave in a fashion indistinguishable from wild rats. The one behavioral difference that is clearly established concerns performance in laboratory learning paradigms. The superiority of domestics in these laboratory tasks speaks more to quieting the concerns of degeneracy theorists than to problems of using domestic Norway rats as subjects representative of their species.
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ISSN 0001-8244 ISBN Medium
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Notes PMID:7325955 Approved no
Call Number Equine Behaviour @ team @ Serial 4144
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Author Chilton, N.B.
Title The use of nuclear ribosomal DNA markers for the identification of bursate nematodes (order Strongylida) and for the diagnosis of infections Type Journal Article
Year 2004 Publication (down) Animal Health Research Reviews / Conference of Research Workers in Animal Diseases Abbreviated Journal Anim Health Res Rev
Volume 5 Issue 2 Pages 173-187
Keywords Animals; Birds; Cats; DNA Primers; DNA, Helminth/*analysis; DNA, Ribosomal/*analysis; Dogs; Horses; Molecular Diagnostic Techniques/veterinary; Ruminants; Strongylida/*genetics; Strongylida Infections/diagnosis/*veterinary
Abstract Many bursate nematodes are of major importance to animal health. Animals are often parasitized by multiple species that differ in their prevalence, relative abundance and/or pathogenicity. Implementation of effective management strategies for these parasites requires reliable methods for their detection in hosts, identification to the species level and measurement of intensity of infection. One major problem is the difficulty of accurately identifying and distinguishing many species of bursate nematode because of the remarkable morphological similarity of their eggs and larvae. The inability to identify, with confidence, individual nematodes (irrespective of their life-cycle stage) to the species level by morphological methods has often led to a search for species-specific genetic markers. Studies over the past 15 years have shown that sequences of the internal transcribed spacers of ribosomal DNA provide useful genetic markers, providing the basis for the development of PCR-based diagnostic tools. Such molecular methods represent powerful tools for studying the systematics, epidemiology and ecology of bursate nematodes and, importantly, for the specific diagnosis of infections in animals and humans, thus contributing to improved control and prevention strategies for these parasites.
Address Department of Biology, University of Saskatchewan, 112 Science Place, Saskatoon, Saskatchewan S7N 5E2, Canada. neil.chilton@usask.ca
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ISSN 1466-2523 ISBN Medium
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Notes PMID:15984323 Approved no
Call Number Equine Behaviour @ team @ Serial 2628
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Author Ishida, N.; Hirano, T.; Mukoyama, H.
Title Detection of aberrant alleles in the D-loop region of equine mitochondrial DNA by single-strand conformation polymorphism (SSCP) analysis Type Journal Article
Year 1994 Publication (down) Animal Genetics Abbreviated Journal Anim Genet
Volume 25 Issue 4 Pages 287
Keywords *Alleles; Animals; Base Sequence; *DNA, Mitochondrial; DNA, Single-Stranded/genetics; Female; Gene Frequency; Genomic Imprinting; Horses/*genetics; Male; Molecular Sequence Data; Pedigree; *Polymorphism, Genetic
Abstract
Address Laboratory of Molecular and Cellular Biology, Japan Racing Association, Tokyo
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ISSN 0268-9146 ISBN Medium
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Notes PMID:7985852 Approved no
Call Number Equine Behaviour @ team @ Serial 2213
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