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| Author | Krishnan, A.; Gandour, J.T.; Ananthakrishnan, S.; Bidelman, G.M.; Smalt, C.J. | ||||
| Title | Functional ear (a)symmetry in brainstem neural activity relevant to encoding of voice pitch: A precursor for hemispheric specialization? | Type | Journal Article | ||
| Year | Publication  |
Brain and Language | Abbreviated Journal | ||
| Volume | In Press, Corrected Proof | Issue | Pages | ||
| Keywords | Auditory; Human; Brainstem; Pitch; Language; Mandarin Chinese; Fundamental frequency-following response (FFR); Functional ear asymmetry; Experience-dependent plasticity; Subcortical | ||||
| Abstract | Pitch processing is lateralized to the right hemisphere; linguistic pitch is further mediated by left cortical areas. This experiment investigates whether ear asymmetries vary in brainstem representation of pitch depending on linguistic status. Brainstem frequency-following responses (FFRs) were elicited by monaural stimulation of the left and right ear of 15 native speakers of Mandarin Chinese using two synthetic speech stimuli that differ in linguistic status of tone. One represented a native lexical tone (Tone 2: T2); the other, T2', a nonnative variant in which the pitch contour was a mirror image of T2 with the same starting and ending frequencies. Two 40-ms portions of f0 contours were selected in order to compare two regions (R1, early; R2 late) differing in pitch acceleration rate and perceptual saliency. In R2, linguistic status effects revealed that T2 exhibited a larger degree of FFR rightward ear asymmetry as reflected in f0 amplitude relative to T2'. Relative to midline (ear asymmetry = 0), the only ear asymmetry reaching significance was that favoring left ear stimulation elicited by T2'. By left- and right-ear stimulation separately, FFRs elicited by T2 were larger than T2' in the right ear only. Within T2', FFRs elicited by the earlier region were larger than the later in both ears. Within T2, no significant differences in FFRS were observed between regions in either ear. Collectively, these findings support the idea that origins of cortical processing preferences for perceptually-salient portions of pitch are rooted in early, preattentive stages of processing in the brainstem. | ||||
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| ISSN | 0093-934x | ISBN | Medium | ||
| Area | Expedition | Conference | |||
| Notes | Approved | no | |||
| Call Number | Equine Behaviour @ team @ | Serial | 5391 | ||
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| Author | Zaine, L.; Ferreira, C.; de O. S. Gomes, M.; Monti, M.; Tortola, L.; Vasconcellos, R.S.; Carciofi, A.C. | ||||
| Title | Faecal IgA concentration is influenced by age in dogs | Type | Journal Article | ||
| Year | 2011 | Publication |
British Journal of Nutrition | Abbreviated Journal | |
| Volume | 106 | Issue | Supplement S1 | Pages | S183-S186 |
| Keywords | Ageing, Immunology, Mucosal immunity, Puppies | ||||
| Abstract | Data comparing age-related alterations in faecal IgA concentrations of dogs are not available in the literature. The present study aimed to compare the faecal concentrations of IgA in puppies, mature and senior dogs. A total of twenty-four beagle dogs were used, including eight puppies (5 months old, four females and four males), eight mature (4·6 years old, eight males) and eight senior dogs (10·6 years old, three males and five females). Fresh faecal samples were collected from each dog for three consecutive days and pooled by animal. After saline extraction, IgA content was measured by ELISA. Data were analysed by one-way ANOVA, and means were compared with Tukey’s test (P,0·05). Results showed that puppies have lower faecal IgA concentrations than mature dogs (P,0·05); senior animals presented intermediary results. The reduced faecal IgA concentration in puppies is consistent with the reduced serum and salivary IgA concentrations reported previously, suggesting a reduced mucosal immunity in this age group. Although some studies have found an increased serum IgA concentration in older dogs, this may differ from the intestinal secretion of IgA, which appears to be lower in some senior animals (four of the eight dogs studied). |
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| Notes | Approved | no | |||
| Call Number | Equine Behaviour @ team @ | Serial | 5993 | ||
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| Author | Lees, P.; Tavernor, W.D. | ||||
| Title | Influence of halothane and catecholamines on heart rate and rhythm in the horse | Type | Journal Article | ||
| Year | 1970 | Publication |
British journal of pharmacology | Abbreviated Journal | Br J Pharmacol |
| Volume | 39 | Issue | 1 | Pages | 149-159 |
| Keywords | Anesthesia, Inhalation; Animals; Arrhythmia/*chemically induced; Atropine/pharmacology; Catecholamines/*pharmacology; Consciousness; Epinephrine/administration & dosage; Ethers; Female; Halothane/*pharmacology; Heart Rate/*drug effects; Horses; Hypercapnia/physiopathology; Isoproterenol/pharmacology; Male; Norepinephrine/pharmacology; Propranolol/pharmacology | ||||
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| Language | English | Summary Language | Original Title | ||
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| Series Volume | Series Issue | Edition | |||
| ISSN | 0007-1188 | ISBN | Medium | ||
| Area | Expedition | Conference | |||
| Notes | PMID:5420092 | Approved | no | ||
| Call Number | refbase @ user @ | Serial | 103 | ||
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| Author | Thomas, K.E.; Annest, J.L.; Gilchrist, J.; Bixby-Hammett, D.M. | ||||
| Title | Non-fatal horse related injuries treated in emergency departments in the United States, 2001-2003 | Type | |||
| Year | 2006 | Publication |
British Journal of Sports Medicine | Abbreviated Journal | Br J Sports Med |
| Volume | 40 | Issue | 7 | Pages | 619-626 |
| Keywords | Accident Prevention/methods; Accidental Falls/prevention & control; Adolescent; Adult; Aged; Animals; Athletic Injuries/*epidemiology/prevention & control; Child; Child, Preschool; Emergency Service, Hospital/*statistics & numerical data; Female; Head Protective Devices/utilization; Health Promotion; *Horses; Humans; Infant; Male; Middle Aged; Patient Education; Sex Distribution; United States/epidemiology | ||||
| Abstract | OBJECTIVE: To characterise and provide nationally representative estimates of persons with non-fatal horse related injuries treated in American emergency departments. METHODS: The National Electronic Injury Surveillance System All Injury Program (NEISS-AIP) is a stratified probability sample comprising 66 hospitals. Data on injuries treated in these emergency departments are collected and reported. NEISS-AIP data on all types (horseback riding and otherwise) of non-fatal horse related injuries from 2001 to 2003 were analysed. RESULTS: An estimated 102,904 persons with non-fatal horse related injuries (35.7 per 100,000 population) were treated in American emergency departments each year from 2001 to 2003 inclusive. Non-fatal injury rates were higher for females (41.5 per 100,000) than for males (29.8 per 100,000). Most patients were injured while mounted on a horse (66.1%), commonly from falling or being thrown by the horse; while not mounted, injuries most often resulted from being kicked by the horse. The body parts most often injured were the head/neck region (23.2%), lower extremity (22.2%), and upper extremity (21.5%). The most common principal diagnoses were contusions/abrasions (31.4%) and fractures (25.2%). For each year that was studied, an estimated 11 502 people sustained traumatic brain injuries from horse related incidents. Overall, more than 11% of those injured were admitted to hospital. CONCLUSIONS: Horse related injuries are a public health concern not just for riders but for anyone in close contact with horses. Prevention programmes should target horseback riders and horse caregivers to promote helmet use and educate participants about horse behaviour, proper handling of horses, and safe riding practices. | ||||
| Address | Office of Statistics and Programming, National Center for Injury Prevention and Control, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA. KEThomas@cdc.gov | ||||
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| Language | English | Summary Language | Original Title | ||
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| Series Volume | Series Issue | Edition | |||
| ISSN | 1473-0480 | ISBN | Medium | ||
| Area | Expedition | Conference | |||
| Notes | PMID:16611723 | Approved | no | ||
| Call Number | Serial | 1866 | |||
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| Author | Albentosa, M.J.; Kjaer, J.B.; Nicol, C.J. | ||||
| Title | Strain and age differences in behaviour, fear response and pecking tendency in laying hens | Type | Journal Article | ||
| Year | 2003 | Publication |
British poultry science | Abbreviated Journal | Br Poult Sci |
| Volume | 44 | Issue | 3 | Pages | 333-344 |
| Keywords | Age Factors; Aggression/*physiology; Animal Husbandry; Animals; *Behavior, Animal; Breeding; Chickens/genetics/*physiology; Fear/*physiology; Feathers/*injuries; Female; Housing, Animal; Population Density; Social Behavior | ||||
| Abstract | 1. Behaviours associated with a high or low tendency to feather peck could be used as predictors of feather pecking behaviour in selective breeding programmes. This study investigated how strain and age at testing influenced responses in behavioural tests. 2. Four layer-type strains (ISA Brown, Columbian Blacktail, Ixworth and a high feather pecking (HP) and a low feather pecking (LP) line of White Leghorn) were reared in 6 same-strain/line pens of 8 birds from one day old. Birds in half the pens were given an open field test, a novel object test and a test with loose feather bundles between 4 and 12 weeks of age and a tonic immobility (TI) test at 13 weeks of age. All pens were tested with fixed feather bundles at 26 weeks, and undisturbed behaviour in the home pens was videoed at 1 and 27 weeks of age. Daily records of plumage damage were used as an indicator of feather pecking activity in the home pens. 3. Strain did not influence novel object test, open field test or loose feather test behaviour, although age effects in all three tests indicated a reduction in fearfulness and/or an increase in exploratory behaviour with increasing age. 4. White Leghorns showed longer TI durations than the other strains but less pecking at fixed feather bundles than ISA Browns and Columbian Blacktails. 5. There were few associations between behaviour in the 5 different tests, indicating that birds did not have overall behavioural traits that were consistent across different contexts. This suggests hens cannot easily be categorised into different behavioural 'types', based on their test responses and casts doubt on the usefulness of tests as predictors of feather pecking. | ||||
| Address | Centre for Behavioural Biology, Division of Farm Animal Science, University of Bristol, Langford, Bristol, England. MAlbentosa@lincoln.ac.uk | ||||
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| Language | English | Summary Language | Original Title | ||
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| Series Volume | Series Issue | Edition | |||
| ISSN | 0007-1668 | ISBN | Medium | ||
| Area | Expedition | Conference | |||
| Notes | PMID:13677322 | Approved | no | ||
| Call Number | refbase @ user @ | Serial | 80 | ||
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| Author | Cheung, C.; Akiyama, T.E.; Ward, J.M.; Nicol, C.J.; Feigenbaum, L.; Vinson, C.; Gonzalez, F.J. | ||||
| Title | Diminished hepatocellular proliferation in mice humanized for the nuclear receptor peroxisome proliferator-activated receptor alpha | Type | Journal Article | ||
| Year | 2004 | Publication |
Cancer research | Abbreviated Journal | Cancer Res |
| Volume | 64 | Issue | 11 | Pages | 3849-3854 |
| Keywords | Animals; Anticholesteremic Agents/pharmacology; Carcinogens/pharmacology; Cell Division; DNA Replication/drug effects; Fatty Acids/metabolism; Hepatocytes/cytology/drug effects/metabolism/*physiology; Humans; Mice; Mice, Transgenic; Oxidation-Reduction; Peroxisome Proliferators/pharmacology; Pyrimidines/pharmacology; Receptors, Cytoplasmic and Nuclear/genetics/*physiology; Species Specificity; Transcription Factors/genetics/*physiology | ||||
| Abstract | Lipid-lowering fibrate drugs function as agonists for the nuclear receptor peroxisome proliferator-activated receptor alpha (PPARalpha). Sustained activation of PPARalpha leads to the development of liver tumors in rats and mice. However, humans appear to be resistant to the induction of peroxisome proliferation and the development of liver cancer by fibrate drugs. The molecular basis of this species difference is not known. To examine the mechanism determining species differences in peroxisome proliferator response between mice and humans, a PPARalpha-humanized mouse line was generated in which the human PPARalpha was expressed in liver under control of the tetracycline responsive regulatory system. The PPARalpha-humanized and wild-type mice responded to treatment with the potent PPARalpha ligand Wy-14643 as revealed by induction of genes encoding peroxisomal and mitochondrial fatty acid metabolizing enzymes and resultant decrease of serum triglycerides. However, surprisingly, only the wild-type mice and not the PPARalpha-humanized mice exhibited hepatocellular proliferation as revealed by elevation of cell cycle control genes, increased incorporation of 5-bromo-2'-deoxyuridine into hepatocyte nuclei, and hepatomegaly. These studies establish that following ligand activation, the PPARalpha-mediated pathways controlling lipid metabolism are independent from those controlling the cell proliferation pathways. These findings also suggest that structural differences between human and mouse PPARalpha are responsible for the differential susceptibility to the development of hepatocarcinomas observed after treatment with fibrates. The PPARalpha-humanized mice should serve as models for use in drug development and human risk assessment and to determine the mechanism of hepatocarcinogenesis of peroxisome proliferators. | ||||
| Address | Laboratory of Metabolism, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA | ||||
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| Language | English | Summary Language | Original Title | ||
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| Series Volume | Series Issue | Edition | |||
| ISSN | 0008-5472 | ISBN | Medium | ||
| Area | Expedition | Conference | |||
| Notes | PMID:15172993 | Approved | no | ||
| Call Number | refbase @ user @ | Serial | 74 | ||
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| Author | Turpeinen, O. | ||||
| Title | Effect of cholesterol-lowering diet on mortality from coronary heart disease and other causes | Type | Journal Article | ||
| Year | 1979 | Publication |
Circulation | Abbreviated Journal | Circulation |
| Volume | 59 | Issue | 1 | Pages | 1-7 |
| Keywords | Coronary Disease/blood/*mortality/prevention & control; Dairy Products; *Dietary Fats; *Fats, Unsaturated; Finland; Humans; Hypercholesterolemia/complications/*diet therapy/mortality; Male; Middle Aged; Neoplasms/mortality | ||||
| Abstract | International statistics indicate that there is a close correlation between the consumption of saturated fats (dairy fats and meat fats) and the mortality from coronary heart disease (CHD), and this conception has been confirmed by many epidemiological studies. Such studies alone, however, cannot prove the existence of a cause-and-effect relationship between these two variables; dietary intervention trials are needed. The Finnish Mental Hospital Study was such a trial, conducted in two hospitals near Helsinki in 1959--1971. Practically total replacement of dairy fats by vegetable oils in the diets of these hospitals was followed by a substantial reduction in the mortality of men from CHD. Total mortality also appeared to be reduced. As to the causes of death other than CHD, none was significantly influenced by dietary change. This was also true for malignant neoplasms. To alleviate the burden of CHD on public health, many investigators have recommended important changes in the quantity and quality of dietary fats. | ||||
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| Language | English | Summary Language | Original Title | ||
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| ISSN | 0009-7322 | ISBN | Medium | ||
| Area | Expedition | Conference | |||
| Notes | PMID:758101 | Approved | no | ||
| Call Number | refbase @ user @ | Serial | 33 | ||
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| Author | Crosby, M.B.; Zhang, J.; Nowling, T.M.; Svenson, J.L.; Nicol, C.J.; Gonzalez, F.J.; Gilkeson, G.S. | ||||
| Title | Inflammatory modulation of PPAR gamma expression and activity | Type | Journal Article | ||
| Year | 2006 | Publication |
Clinical immunology | Abbreviated Journal | Clin Immunol |
| Volume | 118 | Issue | 2-3 | Pages | 276-283 |
| Keywords | Age Factors; Animals; Cell Line, Transformed; Cells, Cultured; Female; Inflammation Mediators/*physiology; Kidney/metabolism; Mesangial Cells/metabolism; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred MRL lpr; Mice, Knockout; Nitric Oxide/biosynthesis; Nitric Oxide Synthase Type II/biosynthesis/genetics; PPAR gamma/*biosynthesis/*genetics/metabolism; Up-Regulation/immunology | ||||
| Abstract | Nitric oxide (NO) production increases with age in the lupus-prone MRL/lpr mouse, paralleling disease activity. One mechanism for excess NO production in MRL/lpr mice may be a defect in down-regulatory mechanisms of the iNOS pathway. A potential modulator of NO is the nuclear hormone receptor peroxisome proliferation activated receptor gamma (PPARgamma). We demonstrate that renal PPARgamma protein expression was altered as disease progressed in MRL/lpr mice, which paralleled increased iNOS protein expression. Additionally, MRL/lpr-derived primary mesangial cells expressed less PPARgamma than BALB/c mesangial cells and produced more NO in response to LPS and IFNgamma. Furthermore, PPARgamma activity was reduced in mesangial cells following exposure to inflammatory mediators. This activity was restored with the addition of a NOS enzyme inhibitor. These results indicate that the activation of inflammatory pathways may lead to reduced activity and expression of PPARgamma, further exacerbating the disease state. | ||||
| Address | Department of Medicine, Medical University of South Carolina, Charleston, SC 29425, USA | ||||
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| Language | English | Summary Language | Original Title | ||
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| Series Volume | Series Issue | Edition | |||
| ISSN | 1521-6616 | ISBN | Medium | ||
| Area | Expedition | Conference | |||
| Notes | PMID:16303334 | Approved | no | ||
| Call Number | refbase @ user @ | Serial | 67 | ||
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| Author | Loveland, K.A. | ||||
| Title | Self-recognition in the bottlenose dolphin: ecological considerations | Type | Journal Article | ||
| Year | 1995 | Publication |
Consciousness and Cognition | Abbreviated Journal | Conscious Cogn |
| Volume | 4 | Issue | 2 | Pages | 254-257 |
| Keywords | Animals; Attention; *Awareness; Body Image; Dolphins/*psychology; Exploratory Behavior; Female; Male; *Self Concept; *Social Environment; Species Specificity; Television; *Visual Perception | ||||
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| Address | Department of Psychiatry and Behavioral Sciences, University of Texas Medical School, Houston 77025, USA | ||||
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| Language | English | Summary Language | Original Title | ||
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| Series Volume | Series Issue | Edition | |||
| ISSN | 1053-8100 | ISBN | Medium | ||
| Area | Expedition | Conference | |||
| Notes | PMID:8521267 | Approved | no | ||
| Call Number | Equine Behaviour @ team @ | Serial | 4161 | ||
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| Author | Hart, D.; Whitlow, J.W.J. | ||||
| Title | The experience of self in the bottlenose dolphin | Type | Journal Article | ||
| Year | 1995 | Publication |
Consciousness and Cognition | Abbreviated Journal | Conscious Cogn |
| Volume | 4 | Issue | 2 | Pages | 244-247 |
| Keywords | Animal Communication; Animals; *Awareness; Body Image; Dolphins/*psychology; Female; Humans; Male; *Self Concept; Social Behavior; Species Specificity; *Television; *Visual Perception | ||||
| Abstract | Marten and Psarakos have presented some evidence which suggests that objective self-awareness and possibly representations of self may characterize the dolphins' experience of self. Their research demonstrates the possibility of similarities in the sense of self between primate species and dolphins, although whether dolphins have subjective self-awareness, personal memories, and theories of self--all important facets of the sense of self in humans--was not examined. Clearly, even this limited evidence was difficult to achieve; the difficulties in adapting methods and coding behavior are quite apparent in their report. Future progress, however, may depend upon clarification of what are the necessary components for a sense of self and an explication of how these might be reflected in dolphin behavior. We are mindful of the authors' point (pp. 219 and 220) that the dolphin lives more in an acoustic than a visual environment. Thus, while tasks relying upon vision may reveal the presence or absence of the sense of self in primates, it might well be the case that in dolphins self-related experiences might be better revealed in auditory tasks. But then, what is the nature of human self-awareness in terms of audition? While both conceptual and methodological hurdles remain, Marten and Psarakos have demonstrated that important questions can be asked about the minds and phenomenal worlds of nonanthropoid species. | ||||
| Address | Department of Psychology, Rutgers University, Camden, New Jersey 08102, USA | ||||
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| Language | English | Summary Language | Original Title | ||
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| Series Volume | Series Issue | Edition | |||
| ISSN | 1053-8100 | ISBN | Medium | ||
| Area | Expedition | Conference | |||
| Notes | PMID:8521264 | Approved | no | ||
| Call Number | Equine Behaviour @ team @ | Serial | 4162 | ||
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