| Records |
| Author |
Brennan, P.A. |
| Title |
The nose knows who's who: chemosensory individuality and mate recognition in mice |
Type |
Journal Article |
| Year |
2004 |
Publication  |
Hormones and Behavior |
Abbreviated Journal |
Horm Behav |
| Volume |
46 |
Issue |
3 |
Pages |
231-240 |
| Keywords |
Animals; Chemoreceptors/physiology; Discrimination Learning/*physiology; Embryo Implantation/physiology; Female; Individuality; Major Histocompatibility Complex/physiology; Male; Mice; Neurons, Afferent/physiology; Nose/cytology/physiology; Perception/physiology; Pregnancy; Pregnancy Maintenance/physiology; Pregnancy, Animal/*physiology; Receptors, Odorant/*physiology; Recognition (Psychology)/*physiology; Sexual Behavior, Animal/*physiology; Smell/*physiology; Urine/physiology; Vomeronasal Organ/cytology/physiology |
| Abstract |
Individual recognition is an important component of behaviors, such as mate choice and maternal bonding that are vital for reproductive success. This article highlights recent developments in our understanding of the chemosensory cues and the neural pathways involved in individuality discrimination in rodents. There appear to be several types of chemosensory signal of individuality that are influenced by the highly polymorphic families of major histocompatibility complex (MHC) proteins or major urinary proteins (MUPs). Both have the capability of binding small molecules and may influence the individual profile of these chemosignals in biological fluids such as urine, skin secretions, or saliva. Moreover, these proteins, or peptides associated with them, can be taken up into the vomeronasal organ (VNO) where they can potentially interact directly with the vomeronasal receptors. This is particularly interesting given the expression of major histocompatibility complex Ib proteins by the V2R class of vomeronasal receptor and the highly selective responses of accessory olfactory bulb (AOB) mitral cells to strain identity. These findings are consistent with the role of the vomeronasal system in mediating individual discrimination that allows mate recognition in the context of the pregnancy block effect. This is hypothesized to involve a selective increase in the inhibitory control of mitral cells in the accessory olfactory bulb at the first level of processing of the vomeronasal stimulus. |
| Address |
Sub-Department of Animal Behaviour, University of Cambridge, Madingley, Cambridge CB3 8AA, UK. pab23@cus.cam.ac.uk |
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Place of Publication |
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| Language |
English |
Summary Language |
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Original Title |
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Series Title |
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Abbreviated Series Title |
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Series Issue |
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Edition |
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| ISSN |
0018-506X |
ISBN |
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Expedition |
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Conference |
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| Notes |
PMID:15325224 |
Approved |
no |
| Call Number |
Equine Behaviour @ team @ |
Serial |
4191 |
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| Author |
Kirkpatrick, J.F.; Liu, I.M.; Turner, J.W.J.; Naugle, R.; Keiper, R. |
| Title |
Long-term effects of porcine zonae pellucidae immunocontraception on ovarian function in feral horses (Equus caballus) |
Type |
Journal Article |
| Year |
1992 |
Publication |
Journal of reproduction and fertility |
Abbreviated Journal |
J Reprod Fertil |
| Volume |
94 |
Issue |
2 |
Pages |
437-444 |
| Keywords |
Animals; Contraception, Immunologic/*veterinary; *Egg Proteins; Estrogens, Conjugated (USP)/urine; Female; Glycoproteins/*pharmacology; Horses/immunology/*physiology; *Membrane Glycoproteins; Ovary/drug effects/*physiology; Progesterone/metabolism; *Receptors, Cell Surface; Swine/immunology; Time Factors; Zona Pellucida/*immunology |
| Abstract |
Ten feral mares free-roaming in Maryland, USA, were inoculated with porcine zonae pellucidae (PZP) protein before the breeding season for three consecutive years (1988-90). Ovarian function was monitored for 51 days during the peak of the breeding season after the third annual PZP inoculation, in seven of these mares and in four untreated control mares, by means of urinary oestrone conjugates and nonspecific progesterone metabolites. None of the ten inoculated mares became pregnant in 1990, compared with 55% of 20 control mares, which included two of the four monitored for ovarian function. Three of the untreated mares demonstrated apparent normal ovarian activity, characterized by preovulatory oestrogen peaks, concurrent progesterone nadirs at ovulation, breeding activity, and luteal-phase progesterone increases after ovulation. Two of the seven monitored PZP-treated mares demonstrated ovulatory cycles that did not result in conception. One was pregnant as a result of conception in 1989 and demonstrated a normal, late-gestation, endocrine profile. The remaining four PZP-treated mares revealed no evidence of ovulation, and urinary oestrogen concentrations were significantly depressed. The experiments indicated that (i) a third consecutive annual PZP booster inoculation is greater than 90% effective in preventing pregnancies in mares and (ii) three consecutive years of PZP treatment may interfere with normal ovarian function as shown by markedly depressed oestrogen secretion. |
| Address |
Deaconess Research Institute, Billings, MT 59102 |
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English |
Summary Language |
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| ISSN |
0022-4251 |
ISBN |
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| Notes |
PMID:1317449 |
Approved |
no |
| Call Number |
refbase @ user @ |
Serial |
145 |
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| Author |
Krcmar, S.; Mikuska, A.; Merdic, E. |
| Title |
Response of Tabanidae (Diptera) to different natural attractants |
Type |
Journal Article |
| Year |
2006 |
Publication |
Journal of Vector Ecology : Journal of the Society for Vector Ecology |
Abbreviated Journal |
J Vector Ecol |
| Volume |
31 |
Issue |
2 |
Pages |
262-265 |
| Keywords |
Animals; Appetitive Behavior/*physiology; Cattle/urine; Diptera/*physiology; Female; Horses/urine; Insect Control/methods; Sheep/urine; Swine/urine; Urine/*physiology |
| Abstract |
The response of female tabanids to natural attractants was studied in the Monjoros Forest along the Nature Park Kopacki rit in eastern Croatia. Tabanids were caught in canopy traps baited with either aged cow, horse, sheep, or pig urine and also in unbaited traps. Tabanids were collected in a significantly higher numbers in traps baited with natural attractants compared to unbaited traps. The number of females of Tabanus bromius, Tabanus maculicornis, Tabanus tergestinus, and Hybomitra bimaculata collected from canopy traps baited with cow urine and traps baited with other natural attractants differed significantly. Females of Haematopota pluvialis were also collected more frequently in canopy traps baited with aged cow urine than in those with aged horse urine, but this difference was not significant. However, the number of females of Haematopota pluvialis collected from canopy traps baited with other natural attractants (sheep and pig urine) differed significantly when compared with aged cow urine baited traps. Canopy traps baited with aged cow urine collected significantly more Tabanus sudeticus than did traps baited with aged pig urine. Finally, the aged cow urine baited canopy traps collected 51 times more tabanids than unbaited traps, while aged horse, aged sheep, and aged pig urine baited traps collected 36, 30, and 22 times as many tabanids, respectively, than unbaited traps. |
| Address |
Department of Biology, JJ Strossmayer University, Lj. Gaja 6, HR-31000 Osijek, Croatia |
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English |
Summary Language |
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Original Title |
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Series Issue |
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Edition |
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| ISSN |
1081-1710 |
ISBN |
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| Notes |
PMID:17249343 |
Approved |
no |
| Call Number |
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Serial |
1836 |
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| Author |
Machnik, M.; Hegger, I.; Kietzmann, M.; Thevis, M.; Guddat, S.; Schanzer, W. |
| Title |
Pharmacokinetics of altrenogest in horses |
Type |
Journal Article |
| Year |
2007 |
Publication |
Journal of Veterinary Pharmacology and Therapeutics |
Abbreviated Journal |
J Vet Pharmacol Ther |
| Volume |
30 |
Issue |
1 |
Pages |
86-90 |
| Keywords |
Administration, Oral; Animals; Chromatography, Liquid/veterinary; Doping in Sports/prevention & control; Horses/*metabolism; Male; Mass Spectrometry/veterinary; Progesterone Congeners/administration & dosage/blood/*pharmacokinetics/urine; Reproducibility of Results; Substance Abuse Detection/veterinary; Trenbolone/administration & dosage/*analogs & derivatives/blood/pharmacokinetics/urine |
| Abstract |
The Federation Equestre Internationale has permitted the use of altrenogest in mares for the control of oestrus. However, altrenogest is also suspicious to misuse in competition horses for its potential anabolic effects and suppression of typical male behaviour, and thus is a controlled drug. To investigate the pharmacokinetics of altrenogest in horses we conducted an elimination study. Five oral doses of 44 mug/kg altrenogest were administered to 10 horses at a dose interval of 24 h. Following administration blood and urine samples were collected at appropriate intervals. Altrenogest concentrations were measured by liquid chromatography-tandem mass spectrometry. The plasma levels of altrenogest reached maximal concentrations of 23-75 ng/mL. Baseline values were achieved within 3 days after the final administration. Urine peak concentrations of total altrenogest ranged from 823 to 3895 ng/mL. Twelve days after the final administration concentrations were below the limit of detection (ca 2 ng/mL). |
| Address |
Institute of Biochemistry, German Sport University, Cologne, Germany. m.machnik@biochem.dshs-koeln.de |
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Place of Publication |
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English |
Summary Language |
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Original Title |
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Series Title |
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Abbreviated Series Title |
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Series Issue |
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Edition |
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| ISSN |
0140-7783 |
ISBN |
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Medium |
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Expedition |
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Conference |
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| Notes |
PMID:17217407 |
Approved |
no |
| Call Number |
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Serial |
1841 |
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| Author |
Stahlbaum, C.C.; Houpt, K.A. |
| Title |
The role of the Flehmen response in the behavioral repertoire of the stallion |
Type |
Journal Article |
| Year |
1989 |
Publication |
Physiology & behavior |
Abbreviated Journal |
Physiol. Behav. |
| Volume |
45 |
Issue |
6 |
Pages |
1207-1214 |
| Keywords |
Animals; Behavior, Animal/*physiology; Circadian Rhythm; Discrimination (Psychology)/physiology; Estrus; Feces; Female; Horses/*physiology; Male; Sexual Behavior, Animal/*physiology; Smell/*physiology; Taste/physiology; Urine |
| Abstract |
The role of the Flehmen response in equine behavior was investigated under field and laboratory conditions. In Experiment 1, a field study made of five stallions on pasture with between three and eighteen mares each during the season indicated the following: 1) The Flehmen response was most frequently preceded by nasal, rather than oral, investigation of substances; 2) The stallions' rate of Flehmen varied with the estrous cycles of the mares; 3) The rate of Flehmen response did not show a variation with time of day; and 4) The Flehmen response was most frequently followed by marking behaviors rather than courtship behaviors. The results suggest that the Flehmen response is not an immediate component of sexual behavior, e.g., courtship of the stallion but may be involved in the overall monitoring of the mare's estrous cycle. Therefore the Flehmen response may contribute to the chemosensory priming of the stallion for reproduction. In Experiment 2 stallions were presented with urine or feces of mares in various stages of the reproductive cycle as well as with their own or other males' urine or feces. The occurrence of sniffing and Flehmen was used to determine the discriminatory ability of the stallions. Stallions can differentiate the sex of a horse on the basis of its feces alone, but cannot differentiate on the basis of urine. This ability may explain the function of fecal marking behavior of stallions. |
| Address |
New York State College of Veterinary Medicine, Cornell University, Ithaca 14853 |
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Place of Publication |
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English |
Summary Language |
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Abbreviated Series Title |
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Series Issue |
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Edition |
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| ISSN |
0031-9384 |
ISBN |
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Medium |
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Conference |
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| Notes |
PMID:2813545 |
Approved |
no |
| Call Number |
refbase @ user @ |
Serial |
44 |
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| Author |
Ziegler, W.H. |
| Title |
[Endocrinological studies in arterial hypertension. Search for phaeochromocytoma] |
Type |
Journal Article |
| Year |
1976 |
Publication |
Schweizerische Medizinische Wochenschrift |
Abbreviated Journal |
Schweiz Med Wochenschr |
| Volume |
106 |
Issue |
34 |
Pages |
1148-1150 |
| Keywords |
Angiography; Blood Volume; Catecholamines/urine; Glucagon/diagnostic use; Histamine/diagnostic use; Humans; Hydrogen-Ion Concentration; Hypertension/*etiology; Methods; Pheochromocytoma/*complications/diagnosis; Tyramine/diagnostic use |
| Abstract |
Elevated urinary catecholamines and their metabolites are the only findings which confirm the presence of pheochromocytoma. This examination is of particular interest if carried out in urine produced after spontaneous hypertensive episodes. Pharmacologic tests when carried out under standard conditions have proven to be a reliable aid in cases of suspected pheochromocytoma. Roentgenographic studies, determination of local plasma catecholamine concentrations and blood volume control should be undertaken in these patients before surgical procedure. |
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German |
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Original Title |
Endokrinologische Untersuchungen bei arterieller Hypertonie. Suche nach Phaochromozytom |
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Edition |
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0036-7672 |
ISBN |
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Conference |
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| Notes |
PMID:12561 |
Approved |
no |
| Call Number |
Equine Behaviour @ team @ |
Serial |
4047 |
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| Author |
Alexander, F.; Davies, M.E. |
| Title |
Studies on vitamin B12 in the horse |
Type |
Journal Article |
| Year |
1969 |
Publication |
The British veterinary journal |
Abbreviated Journal |
Br. Vet. J. |
| Volume |
125 |
Issue |
4 |
Pages |
169-176 |
| Keywords |
Animals; Biological Assay; Cattle; Chickens; Feces/analysis; Horses/*metabolism; Humans; Lactobacillus/metabolism; Rabbits; Rats; Sheep; Urine/analysis; Vitamin B 12/*analysis |
| Abstract |
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English |
Summary Language |
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Original Title |
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Abbreviated Series Title |
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Series Issue |
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Edition |
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| ISSN |
0007-1935 |
ISBN |
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Conference |
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| Notes |
PMID:5814055 |
Approved |
no |
| Call Number |
refbase @ user @ |
Serial |
116 |
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| Author |
Dirikolu, L.; Lehner, A.F.; Karpiesiuk, W.; Hughes, C.; Woods, W.E.; Boyles, J.; Harkins, J.D.; Troppmann, A.; Tobin, T. |
| Title |
Detection, quantification, metabolism, and behavioral effects of selegiline in horses |
Type |
Journal Article |
| Year |
2003 |
Publication |
Veterinary Therapeutics : Research in Applied Veterinary Medicine |
Abbreviated Journal |
Vet Ther |
| Volume |
4 |
Issue |
3 |
Pages |
257-268 |
| Keywords |
Administration, Oral; Animals; Behavior, Animal/drug effects; Female; Horses/*metabolism; Mass Spectrometry/veterinary; Monoamine Oxidase Inhibitors/administration & dosage/blood/*pharmacokinetics/pharmacology/urine; Selegiline/administration & dosage/blood/*pharmacokinetics/pharmacology/urine; Substance Abuse Detection/veterinary |
| Abstract |
Selegiline ([R]-[-]N,alpha-dimethyl-N-2- propynylphenethylamine or l-deprenyl), an irreversible inhibitor of monoamine oxidase, is a classic antidyskinetic and antiparkinsonian agent widely used in human medicine both as monotherapy and as an adjunct to levodopa therapy. Selegiline is classified by the Association of Racing Commissioners International (ARCI) as a class 2 agent, and is considered to have high abuse potential in racing horses. A highly sensitive LC/MS/MS quantitative analytical method has been developed for selegiline and its potential metabolites amphetamine and methamphetamine using commercially available deuterated analogs of these compounds as internal standards. After administering 40 mg of selegiline orally to two horses, relatively low (<60 ng/ml) concentrations of parent selegiline, amphetamine, and methamphetamine were recovered in urine samples. However, relatively high urinary concentrations of another selegiline metabolite were found, tentatively identified as N- desmethylselegiline. This metabolite was synthesized and found to be indistinguishable from the new metabolite recovered from horse urine, thereby confirming the chemical identity of the equine metabolite. Additionally, analysis of urine samples from four horses dosed with 50 mg of selegiline confirmed that N-desmethylselegiline is the major urinary metabolite of selegiline in horses. In related behavior studies, p.o. and i.v. administration of 30 mg of selegiline produced no significant changes in either locomotor activities or heart rates. |
| Address |
Department of Biomedical Sciences, College of Veterinary Medicine, Nursing and Allied Health, Tuskegee University, Tuskegee, AL 36088, USA |
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English |
Summary Language |
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Series Title |
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Abbreviated Series Title |
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Series Issue |
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Edition |
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| ISSN |
1528-3593 |
ISBN |
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Medium |
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Expedition |
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Conference |
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| Notes |
PMID:15136987 |
Approved |
no |
| Call Number |
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Serial |
1901 |
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