Records |
Author |
Bannasch, D.; Rinaldo, C.; Millon, L.; Latson, K.; Spangler, T.; Hubberty, S.; Galuppo, L.; Lowenstine, L. |
Title |
SRY negative 64,XX intersex phenotype in an American saddlebred horse |
Type |
Journal Article |
Year |
2007 |
Publication |
Veterinary Journal (London, England : 1997) |
Abbreviated Journal |
Vet J |
Volume |
173 |
Issue |
2 |
Pages |
437-439 |
Keywords |
Animals; Female; Genitalia/abnormalities; Hermaphroditism/*veterinary; Horse Diseases/*diagnosis/genetics; Horses/*genetics/*physiology; Karyotyping; Phenotype; Sex Differentiation; Sex Differentiation Disorders/diagnosis/veterinary; Sex-Determining Region Y Protein/genetics/*metabolism |
Abstract |
A female American saddlebred horse was presented for surgical correction of a possible pseudohermaphrodite condition. The horse had abnormal external genitalia and exhibited stallion-like behaviour. No evidence of uterine or ovarian tissue was identified on laparoscopic examination, but hypoplastic testicular-like tissue was removed, although this was found to contain no spermatogonia upon histopathological examination. A karyotype was performed and showed the normal chromosomal complement for a female horse (64,XX). Polymerase chain reaction to detect the SRY gene was negative in peripheral blood as well as the testicular-like tissue. This case represents the first report of an SRY negative XX-male sex reversal intersex phenotype, which is a potentially inherited condition, in an American saddlebred horse. |
Address |
Department of Population Health and Reproduction, School of Veterinary Medicine, University of California, Davis, CA 95616, USA. dlbannasch@ucdavis.edu |
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Place of Publication |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
1090-0233 |
ISBN |
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Notes |
PMID:16386440 |
Approved |
no |
Call Number |
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Serial |
1882 |
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Author |
Dabareiner, R.M.; Sullins, K.E.; White, N.A. 2nd |
Title |
Progression of femoropatellar osteochondrosis in nine young horses. Clinical, radiographic and arthroscopic findings |
Type |
Journal Article |
Year |
1993 |
Publication |
Veterinary Surgery : VS : the Official Journal of the American College of Veterinary Surgeons |
Abbreviated Journal |
Vet Surg |
Volume |
22 |
Issue |
6 |
Pages |
515-523 |
Keywords |
Animals; Arthroscopy/veterinary; Debridement/veterinary; Exudates and Transudates; Female; Femur; Follow-Up Studies; Horse Diseases/*diagnosis/radiography/surgery; Horses; Lameness, Animal/*etiology; Male; Osteochondritis/diagnosis/radiography/surgery/*veterinary; Patella; Stifle; Treatment Outcome |
Abstract |
The clinical and radiographic progression, and arthroscopic findings for nine young horses (< 1 year of age) with femoropatellar osteochondrosis (OCD) are presented. Horses had a 2 to 12 week history of bilateral (8 horses) or unilateral (1 horse) hindlimb lameness. The most consistent clinical signs included femoropatellar joint distention and bilateral hindlimb lameness. At the onset of clinical signs, radiographic lesions were not present (4 horses) or subtle (5 horses), but were easily identified on radiographs taken 4 to 24 weeks later. Arthroscopic surgery was delayed until radiographic changes became obvious. Surgical findings in 20 femoropatellar joints were most commonly osteochondral “flaps” located on the proximal lateral trochlear ridge of the femur and were larger than had been indicated by the radiographs. Eight horses were being used for their intended purpose, which was racing (3 horses were racing and 3 were in race training), dressage (1 horse) or pleasure riding (1 horse). One horse required a second surgery when similar lesions developed on the opposite stifle, and was euthanatized 2 months later because of persistent lameness. One clinical signs are observed, osteochondrosis lesions of the distal femur can progress in foals younger than 9 months of age and the full extent of the radiographic lesion may take several weeks to develop. |
Address |
Marion duPont Scott Equine Medical Center, Virginia-Maryland Regional College of Veterinary Medicine, Leesburg, Virginia |
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Place of Publication |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0161-3499 |
ISBN |
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Medium |
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Expedition |
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Conference |
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Notes |
PMID:8116209 |
Approved |
no |
Call Number |
Equine Behaviour @ team @ |
Serial |
3748 |
Permanent link to this record |