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Author Quiroz-Rothe, E.; Novales, M.; Aguilera-Tejero, E.; Rivero, J.L.L.
Title Polysaccharide storage myopathy in the M. longissimus lumborum of showjumpers and dressage horses with back pain Type Journal Article
Year 2002 Publication (up) Equine Veterinary Journal Abbreviated Journal Equine Vet J
Volume 34 Issue 2 Pages 171-176
Keywords Amylases/analysis; Animals; Back Pain/etiology/*veterinary; Biopsy; Carbohydrate Metabolism, Inborn Errors/diagnosis/pathology/*veterinary; Diagnosis, Differential; Glycogen/analysis; Horse Diseases/*diagnosis/pathology; Horses; Microscopy, Electron; Muscle, Skeletal/pathology; Muscular Diseases/diagnosis/pathology/*veterinary; Polysaccharides/*metabolism; Rhabdomyolysis/diagnosis/pathology/veterinary
Abstract This study was designed to investigate whether horses with clinical signs of back pain due to suspected soft tissue injuries were affected by polysaccharide storage myopathy (PSSM). Diagnosis of PSSM in muscle biopsies obtained from the M. longissimus lumborum of 5 showjumpers and 4 dressage horses with a history of back pain is reported. M. longissimus lumborum biopsies of these horses were characterised histopathologically and in 3/9 cases also by electron microscopy. Observations were compared with M. gluteus biopsies of the same horses, and with M. gluteus biopsies obtained from 6 Standardbreds with recurrent exertional rhabdomyolysis and from 6 healthy trotters. M. longissimus biopsies from horses with back pain showed pathognomonic signs of PSSM, i.e. high glycogen and/or abnormal complex amylase-resistant polysaccharide deposits. Similar features were found in M. gluteus biopsies of the same horses. Sections of horses with rhabdomyolysis had increased PAS stain when compared with healthy horses, but did not show amylase-resistant material. Qualitative observations were corroborated by quantitative histochemistry (optical densities) of sections stained with PAS and amylase PAS. This study demonstrated the presence of PSSM in the M. longissimus of showjumpers and dressage horses with back pain and indicates that epaxial muscle biopsy is an option in diagnosing back problems in horses when clinical examination and imaging techniques do not provide a precise diagnosis.
Address Department of Comparative Anatomy, Faculty of Veterinary Science, University of Cordoba, Spain
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0425-1644 ISBN Medium
Area Expedition Conference
Notes PMID:11905436 Approved no
Call Number Equine Behaviour @ team @ Serial 3727
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Author Westerduin, F.E.; Lankveld, D.P.K.; van der Velden, M.A.; Back, W.; Sloet van Oldruitenborgh-Oosterbaan, M.M.
Title [Splenectomy in a dressage pony: end of sports career?] Type Journal Article
Year 2003 Publication (up) Tijdschrift Voor Diergeneeskunde Abbreviated Journal Tijdschr Diergeneeskd
Volume 128 Issue 13 Pages 406-411
Keywords Animals; Biopsy/veterinary; Colic/surgery/veterinary; Horse Diseases/pathology/*surgery/ultrasonography; Horses; Laparotomy/veterinary; Male; Splenectomy/*veterinary; Splenomegaly/surgery/ultrasonography/*veterinary; *Sports
Abstract A 14-year-old Arabian cross-bred gelding was referred to the University Clinic because of mild, recurrent signs of colic for 5 days. The pony showed icteric mucous membranes, haemolytic blood, and dark coloured urine. Internal examination did not give a clear diagnosis. Unidentified intra-abdominal strands were found and haemorrhagic abdominocentesis led to the decision to perform an exploratory laparatomy. An extremely enlarged spleen was the sole finding. A splenal biopsy sample was taken and surgery was completed. The pony remained colicky, so the spleen was examined by ultrasonography. After this examination, the tentative diagnosis 'tumour of the spleen' was made and splenectomy was performed. Pathological examination of the spleen revealed splenomegaly caused by infarctions of unknown origin. Eight weeks after surgery, the pony started again in dressage competition. Six months after splenectomy, the pony won the provincial dressage competition.
Address Hoofdafdeling Gezondheidszorg Paard, Faculteit der Diergeneeskunde, Universiteit Utrecht, Yalelaan 12-16, 3584 CM Utrecht. fenna-lambert@planet.nl
Corporate Author Thesis
Publisher Place of Publication Editor
Language Dutch Summary Language Original Title Splenectomie bij een dressuurpony: einde sportcarriere?
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0040-7453 ISBN Medium
Area Expedition Conference
Notes PMID:12870176 Approved no
Call Number Equine Behaviour @ team @ Serial 3722
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