| Records |
| Author |
Gil, M.; Bhatt, R.; Picotte, K.B.; Hull, E.M. |
| Title |
Sexual experience increases oxytocin receptor gene expression and protein in the medial preoptic area of the male rat |
Type |
Abstract |
| Year |
2013 |
Publication |
Psychoneuroendocrinology |
Abbreviated Journal |
Psychoneuroendocrinology |
| Volume |
38 |
Issue |
9 |
Pages |
1688-1697 |
| Keywords |
Oxytocin; Oxytocin receptor; Sexual behavior; Sexual experience; Medial preoptic area; Hypothalamus; Rats |
| Abstract |
Oxytocin (OT) promotes social and reproductive behaviors in mammals, and OT deficits may be linked to disordered social behaviors like autism and severe anxiety. Male rat sexual behavior is an excellent model for OT regulation of behavior, as its pattern and neural substrates are well characterized. We previously reported that OT microinjected into the medial preoptic area (MPOA), a major integrative site for male sexual behavior, facilitates copulation in sexually experienced male rats, whereas intra-MPOA injection of an OT antagonist (OTA) inhibits copulation. In the present studies, copulation on the day of sacrifice stimulated OTR mRNA expression in the MPOA, irrespective of previous sexual experience, with the highest levels observed in first-time copulators. In addition, sexually experienced males had higher levels of OTR protein in the MPOA than sexually naïve males and first-time copulators. Finally, intra-MPOA injection of OT facilitated mating in sexually naive males. Others have reported a positive correlation between OT mRNA levels and male sexual behavior. Our studies show that OT in the MPOA facilitates mating in both sexually naive and experienced males, some of the behavioral effects of OT are mediated by the OTR, and sexual experience is associated with increased OTR expression in the MPOA. Taken together, these data suggest a reciprocal interaction between central OT and behavior, in which OT facilitates copulation and copulation stimulates the OT/OTR system in the brain. |
| Address |
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| Corporate Author |
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Thesis |
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| Publisher |
Pergamon Press. |
Place of Publication |
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Editor |
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| Language |
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Summary Language |
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Original Title  |
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| Series Editor |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
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Edition |
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| ISSN |
0306-4530 |
ISBN |
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Medium |
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| Area |
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Expedition |
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Conference |
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| Notes |
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Approved |
no |
| Call Number |
Equine Behaviour @ team @ S0306-4530(13)00040-1 |
Serial |
5724 |
| Permanent link to this record |
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| Author |
Cancedda, M. |
| Title |
[Social and behavioral organization of horses on the Giara (Sardinia): distribution and aggregation] |
Type |
Journal Article |
| Year |
1990 |
Publication |
Bollettino della Societa italiana di biologia sperimentale |
Abbreviated Journal |
Boll Soc Ital Biol Sper |
| Volume |
66 |
Issue |
11 |
Pages |
1089-1096 |
| Keywords |
Animals; *Animals, Wild/physiology/psychology; Environment; Female; *Horses/physiology/psychology; Italy; Male; Population Density; Sexual Behavior, Animal; *Social Behavior; Social Dominance; Water |
| Abstract |
In this paper some considerations on the environment of the 42 Kmq of the volcanic-basaltic Giara tableland are discussed. Conditioning by the environment and its effect on the distribution of a population of 712 horses is illustrated in view of their social and behavioural organization. |
| Address |
Istituto di Fisiologia Generale e Speciale, Universita di Sassari |
| Corporate Author |
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Thesis |
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| Publisher |
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Place of Publication |
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Editor |
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| Language |
Italian |
Summary Language |
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Original Title |
Introduzione all'organizzazione sociale e comportamentale dei cavallini sulla Giara (Sardegna): distribuzione ed aggregazione |
| Series Editor |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
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Edition |
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| ISSN |
0037-8771 |
ISBN |
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Medium |
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| Area |
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Expedition |
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Conference |
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| Notes |
PMID:2095819 |
Approved |
no |
| Call Number |
refbase @ user @ |
Serial |
673 |
| Permanent link to this record |
