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Author Gonzalez-Fernandez, J.M.; Atta, S.E.
Title Facilitated transport of oxygen in the presence of membranes in the diffusion path Type Journal Article
Year 1982 Publication Biophysical Journal Abbreviated Journal Biophys J
Volume 38 Issue 2 Pages 133-141
Keywords Animals; Biological Transport, Active; Cell Membrane/*metabolism; Diffusion; Dogs; Horses; Humans; Kinetics; Mathematics; *Models, Biological; Muscles/*metabolism; Oxygen/*metabolism
Abstract Most of the experimental observations on facilitated transport have been done with millipore filters, and all the theoretical studies have assumed homogeneous spatial properties. In striated muscle there exist membranes that may impede the diffusion of the carrier myoglobin. In this paper a theoretical study is undertaken to analyze the transport in the presence of membranes in the diffusion path. For the numerical computations physiologically relevant values of the parameters were chosen. The numerical results indicate that the presence of membranes tends to decrease the facilitation. For the nonlinear chemical kinetics of the reaction of oxygen with the carrier, this decrement also depends on the location of the membranes. At the higher oxygen concentration side of each membrane the flow of combined oxygen is transferred to the flow of dissolved oxygen. The reverse process occurs at the lower concentration side. Jump discontinuities of the concentration of the oxygen-carrier compound at each membrane are associated with these transfers. The decrement of facilitation is due to the cumulative effect of these jump discontinuities.
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Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0006-3495 ISBN Medium
Area Expedition Conference
Notes (down) PMID:7093418 Approved no
Call Number Equine Behaviour @ team @ Serial 3806
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Author Donnelly, J.; Phipps, L.P.; Watkins, K.L.
Title Evidence of maternal antibodies to Babesia equi and B caballi in foals of seropositive mares Type Journal Article
Year 1982 Publication Equine Veterinary Journal Abbreviated Journal Equine Vet J
Volume 14 Issue 2 Pages 126-128
Keywords Animals; Antibodies/*analysis; Babesia/*immunology; Complement Fixation Tests; Female; Horses/*immunology; Immunity, Maternally-Acquired; Male; Time Factors
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Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0425-1644 ISBN Medium
Area Expedition Conference
Notes (down) PMID:7084196 Approved no
Call Number Equine Behaviour @ team @ Serial 2280
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Author Alexander, F.
Title Effect of phenylbutazone on electrolyte metabolism in ponies Type Journal Article
Year 1982 Publication The Veterinary record Abbreviated Journal Vet. Rec.
Volume 110 Issue 12 Pages 271-272
Keywords Animals; Chlorides/metabolism; Electrolytes/*metabolism; Horses/*metabolism; Male; Phenylbutazone/*pharmacology; Sodium/metabolism
Abstract Phenylbutazone administered in therapeutic doses to ponies decreased urinary sodium and chloride excretion. The volume and osmolality of the urine was unaffected as was potassium excretion. Faecal excretion of chloride decreased and that of potassium increased, while faecal sodium excretion was unaffected. Plasma pH, bicarbonate and total carbon dioxide decreased after phenylbutazone administration. Packed cell volume, plasma sodium, potassium, carbon dioxide tension and chloride were unchanged.
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Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0042-4900 ISBN Medium
Area Expedition Conference
Notes (down) PMID:7080416 Approved no
Call Number refbase @ user @ Serial 109
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Author Andersson, P.; Kvassman, J.; Lindstrom, A.; Olden, B.; Pettersson, G.
Title Effect of NADH on the pKa of zinc-bound water in liver alcohol dehydrogenase Type Journal Article
Year 1981 Publication European Journal of Biochemistry / FEBS Abbreviated Journal Eur J Biochem
Volume 113 Issue 3 Pages 425-433
Keywords Alcohol Oxidoreductases/*metabolism; Aldehydes/metabolism; Animals; Binding Sites; Cinnamates/metabolism; Horses; Hydrogen-Ion Concentration; Kinetics; Ligands; Liver/*metabolism; NAD/*metabolism; Water/metabolism; Zinc/metabolism
Abstract Equilibrium constants for coenzyme binding to liver alcohol dehydrogenase have been determined over the pH range 10--12 by pH-jump stop-flow techniques. The binding of NADH or NAD+ requires the protonated form of an ionizing group (distinct from zinc-bound water) with a pKa of 10.4. Complex formation with NADH exhibits an additional dependence on the protonation state of an ionizing group with a pKa of 11.2. The binding of trans-N,N-dimethylaminocinnamaldehyde to the enzyme . NADH complex is prevented by ionization of the latter group. It is concluded from these results that the pKa-11.2-dependence of NADH binding most likely derives from ionization of the water molecule bound at the catalytic zinc ion of the enzyme subunit. The pKa value of 11.2 thus assigned to zinc-bound water in the enzyme . NADH complex appears to be typical for an aquo ligand in the inner-sphere ligand field provided by the zinc-binding amino acid residues in liver alcohol dehydrogenase. This means that the pKa of metal-bound water in zinc-containing enzymes can be assumed to correlate primarily with the number of negatively charged protein ligands coordinated by the active-site zinc ion.
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Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0014-2956 ISBN Medium
Area Expedition Conference
Notes (down) PMID:7011796 Approved no
Call Number Equine Behaviour @ team @ Serial 3810
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Author Klingel, H.
Title Social organization of feral horses Type Journal Article
Year 1982 Publication Journal of Reproduction and Fertility. Supplement Abbreviated Journal J Reprod Fertil Suppl
Volume 32 Issue Pages 89-95
Keywords Animals; Animals, Wild; Female; Horses/*physiology; Male; Sexual Behavior, Animal; *Social Behavior; Territoriality
Abstract The basic social unit in feral horses is the family group consisting of one stallion, one to a few unrelated mares and their foals. Surplus stallions associate in bachelor groups. Stallions are instrumental in bringing mares together in a unit which then persists even without a stallion. The similarity of social organization in populations living in a variety of different habitats indicates that feral horses have reverted to the habits of their wild ancestors, and that domestication has had no influence on this basic behavioural feature.
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Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0449-3087 ISBN Medium
Area Expedition Conference
Notes (down) PMID:6962906 Approved no
Call Number refbase @ user @ Serial 1958
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Author Turner, J.W.J.; Kirkpatrick, J.F.
Title Androgens, behaviour and fertility control in feral stallions Type Journal Article
Year 1982 Publication Journal of reproduction and fertility. Supplement Abbreviated Journal J Reprod Fertil Suppl
Volume 32 Issue Pages 79-87
Keywords Animals; Animals, Wild; Copulation/drug effects; Female; *Fertility/drug effects; Horses/*physiology; Male; Periodicity; Pregnancy; Seasons; *Sexual Behavior, Animal/drug effects; Sexual Maturation; Sperm Count; Sperm Motility/drug effects; Testosterone/*blood/pharmacology
Abstract This field study of feral stallions in Montana and Idaho examines and correlates the seasonal pattern of plasma androgens and specific sociosexual behaviour and reports the effect of a long-acting androgenic steroid on this behaviour and on fertility. Plasma testosterone was measured by competitive protein binding assay in samples obtained by jugular venepuncture from captured animals. In samples taken from 34 sexually mature stallions in 6 different months during the year, a definite seasonal pattern in testosterone was present, with a peak in May (3.04 +/- 0.63 ng/ml) and a nadir in December (1.55 +/- 0.34 ng/ml). Values were less than 2.0 ng/ml in non-breeding months and greater than 2.4 ng/ml in breeding months. Behavioural endpoints measured were (1) stallion scent marking in response to elimination by mares (elimination marking), (2) mounting and (3) copulation. The frequencies of each of these endpoints followed closely the seasonal pattern seen for plasma androgens. In the fertility study microcapsulated testosterone propionate (microTP) was administered i.m. to 10 harem stud stallions 3 months before the 1980 breeding season. In these stallions and in 10 control harem studs, the above behavioural endpoints were examined in the 1980 and 1981 breeding seasons, and foal counts were made in 1981. There were no direct inhibitory or stimulatory effects of microTP treatment on any of the behavioural endpoints in either year. In 1981 foals were produced in 87.5% of the control bands and 28.4% of the microTP-treated bands. These results indicate that microencapsulated testosterone propionate can provide effective fertility control in feral horses without causing significant alterations in sociosexual behaviour.
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Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0449-3087 ISBN Medium
Area Expedition Conference
Notes (down) PMID:6962905 Approved no
Call Number refbase @ user @ Serial 138
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Author Beaver, B.V.
Title Problems & values associated with dominance Type Journal Article
Year 1981 Publication Veterinary medicine, small animal clinician : VM, SAC Abbreviated Journal Vet Med Small Anim Clin
Volume 76 Issue 8 Pages 1129-1131
Keywords Animals; *Animals, Domestic; *Behavior, Animal; Cats; Cattle; Dogs; Horses; *Social Dominance; Swine
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Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0042-4889 ISBN Medium
Area Expedition Conference
Notes (down) PMID:6914851 Approved no
Call Number refbase @ user @ Serial 678
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Author Alexander, D.J.
Title Ecological aspects of influenza A viruses in animals and their relationship to human influenza: a review Type Journal Article
Year 1982 Publication Journal of the Royal Society of Medicine Abbreviated Journal J R Soc Med
Volume 75 Issue 10 Pages 799-811
Keywords Animals; *Animals, Domestic; Bird Diseases/transmission; Birds; Disease Outbreaks; Ecology; Horse Diseases/transmission; Horses; Humans; Influenza A virus/genetics/isolation & purification; Influenza, Human/microbiology/*transmission/veterinary; Swine; Swine Diseases/transmission; Zoonoses/transmission
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Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0141-0768 ISBN Medium
Area Expedition Conference
Notes (down) PMID:6752410 Approved no
Call Number Equine Behaviour @ team @ Serial 2689
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Author Keiper, R.; Houpt, K.
Title Reproduction in feral horses: an eight-year study Type Journal Article
Year 1984 Publication American journal of veterinary research Abbreviated Journal Am J Vet Res
Volume 45 Issue 5 Pages 991-995
Keywords Abortion, Veterinary/epidemiology; Anestrus; Animal Population Groups/*physiology; Animals; Animals, Wild/*physiology; Birth Rate; Female; Fertility; Horse Diseases/epidemiology; Horses/*physiology; Lactation; Male; Maryland; Pregnancy; *Reproduction; Seasons; Sex Ratio; Virginia
Abstract The reproductive rate and foal survival of the free-ranging ponies on Assateague Island National Seashore were studied for 8 years, 1975 to 1982. Most (52%) of the 86 foals were born in May, 13% were born in April, 22.6% in June, 10.4% in July, and less than 1% in August and September. The mean foaling rate was 57.1 +/- 3.9% and the survival rate was 88.3 +/- 3.6%. Forty-eight colts and 55 fillies were born (sex ratio 53% female). Mares less than 3 years old did not foal and the foaling rate of 3-year-old mares was only 23%, that of 4-year-old mares was 46%, that of 5-year-old mares was 53%, and 6-year-old mares was 69%. The relatively poor reproduction rate was believed to be a consequence of the stress of lactating while carrying a foal when forage quality on the island was low. The hypothesis was supported by the higher reproductive rate (74.4 +/- 2.4%) of the ponies in the Chincoteague National Wildlife Refuge on the southern part of the island. Their foals are weaned and sold in July each year. Despite the low reproductive rate on Assateague Island National Seashore , the number of ponies increased from 43 to 80, a 90% increase in the 8-year period or greater than 10%/yr. There were 24 deaths and 8 dispersals from the study area.
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Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0002-9645 ISBN Medium
Area Expedition Conference
Notes (down) PMID:6732036 Approved no
Call Number refbase @ user @ Serial 665
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Author Barton, M.D.; Hughes, K.L.
Title Ecology of Rhodococcus equi Type Journal Article
Year 1984 Publication Veterinary Microbiology Abbreviated Journal Vet Microbiol
Volume 9 Issue 1 Pages 65-76
Keywords Actinomycetales/growth & development/immunology/*isolation & purification; Animal Husbandry; Animals; Antigens, Bacterial/immunology; Artiodactyla/*microbiology; Australia; Digestive System/microbiology; Ecology; Feces/*microbiology; Horses/*microbiology; Hypersensitivity, Delayed; Rabbits/microbiology; *Soil Microbiology
Abstract A selective broth enrichment technique was used to study the distribution of Rhodococcus equi in soil and grazing animals. Rhodococcus equi was isolated from 54% of soils examined and from the gut contents, rectal faeces and dung of all grazing herbivorous species examined. Rhodococcus equi was not isolated from the faeces or dung of penned animals which did not have access to grazing. The isolation rate from dung was much higher than from other samples and this was found to be due to the ability of R. equi to multiply more readily in dung. Delayed hypersensitivity tests were carried out on horses, sheep and cattle, but only horses reacted significantly. The physiological characteristics of R. equi and the nature of its distribution in the environment suggested that R. equi is a soil organism.
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Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0378-1135 ISBN Medium
Area Expedition Conference
Notes (down) PMID:6719819 Approved no
Call Number Equine Behaviour @ team @ Serial 2688
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