Records |
Author |
Alexander, F. |
Title |
The effect of diuretics on the faecal excretion of water and electrolytes in horses |
Type |
Journal Article |
Year |
1977 |
Publication |
British journal of pharmacology |
Abbreviated Journal |
Br J Pharmacol |
Volume |
60 |
Issue |
4 |
Pages |
589-593 |
Keywords |
Animals; Body Water/*metabolism; Chlorides/metabolism; Electrolytes/*metabolism; Feces/*analysis; Furosemide/*pharmacology; Horses; Hydrochlorothiazide/*pharmacology; Male; Potassium/metabolism; Sodium/metabolism; Time Factors |
Abstract |
1. The effect on plasma, urinary and faecal electrolytes of frusemide and hydrochlorthiazide was measured in ponies, mean weight 180 kg. 2. The rapid loss in urine of large quantities of sodium had only a small effect on plasma sodium concentration. 3. Faecal sodium excretion was increased substantially after the administration of frusemide. 4. Frusemide increased faecal potassium during the 48 h following administration and faecal water in the 24/48 h period. It also produced a hypopotassaemia. 5. Hydrochlorthiazide increased faecal chloride during the 24 h after administration. 6. Frusemide increased the intestinal transit time of both liquid (polyethylene glycol) and particulate (Cr2O3) markers. |
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Edition |
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ISSN |
0007-1188 |
ISBN |
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Notes |
PMID:907872 |
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no |
Call Number |
refbase @ user @ |
Serial |
111 |
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Author |
Waran, N.K.; Robertson, V.; Cuddeford, D.; Kokoszko, A.; Marlin, D.J. |
Title |
Effects of transporting horses facing either forwards or backwards on their behaviour and heart rate |
Type |
Journal Article |
Year |
1996 |
Publication |
The Veterinary Record |
Abbreviated Journal |
Vet. Rec. |
Volume |
139 |
Issue |
1 |
Pages |
7-11 |
Keywords |
Animals; *Behavior, Animal; Female; *Heart Rate; *Horses; Male; Posture/*physiology; *Transportation |
Abstract |
The effects of transporting horses facing either forwards or backwards were compared by transporting six thoroughbred horses in pairs in a lorry on one journey facing in the direction of travel, and on another journey facing away from the direction of travel, over a standard one-hour route. Heart rate monitors were used to record their heart rate before, during and after the journey and the horses' behaviour was recorded by scan sampling each horse every other minute. The average heart rate was significantly lower (P < 0.05) when the horses were transported facing backwards, and they also tended to rest on their rumps more (P = 0.059). In the forward-facing position, the horses moved more frequently (P < 0.05) and tended to hold their necks in a higher than normal position and to vocalise more frequently (P = 0.059). During loading the average peak heart rate was 38 bpm lower (P < 0.05) when the horses were backed into the horse box for rear-facing transport than when they were loaded facing forwards. However, there was no difference between transport facing forwards or backwards in terms of the peak unloading heart rate, or the average heart rate during loading or unloading. The horses seemed to find being transported less physically stressful when they were facing backwards than when they were facing forwards. |
Address |
Institute of Ecology and Resource Management, University of Edinburgh, School of Agriculture |
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English |
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Series Editor |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0042-4900 |
ISBN |
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Conference |
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Notes |
PMID:8966985 |
Approved |
no |
Call Number |
refbase @ user @ |
Serial |
1938 |
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Author |
Grubb, T.L.; Foreman, J.H.; Benson, G.J.; Thurmon, J.C.; Tranquilli, W.J.; Constable, P.D.; Olson, W.O.; Davis, L.E. |
Title |
Hemodynamic effects of calcium gluconate administered to conscious horses |
Type |
Journal Article |
Year |
1996 |
Publication |
Journal of veterinary internal medicine / American College of Veterinary Internal Medicine |
Abbreviated Journal |
J Vet Intern Med |
Volume |
10 |
Issue |
6 |
Pages |
401-404 |
Keywords |
Animals; Blood Pressure/drug effects/physiology; Calcium/blood; Calcium Gluconate/administration & dosage/*pharmacology; Cardiac Output/drug effects/physiology; Consciousness/*physiology; Dose-Response Relationship, Drug; Female; Heart Rate/drug effects/physiology; Hemodynamic Processes/*drug effects/physiology; Horses/blood/*physiology; Infusions, Intravenous; Male; Myocardial Contraction/drug effects/physiology; Respiration/drug effects/physiology; Stroke Volume/drug effects/physiology; Time Factors |
Abstract |
Calcium gluconate was administered to conscious horses at 3 different rates (0.1, 0.2, and 0.4 mg/kg/min for 15 minutes each). Serum calcium concentrations and parameters of cardiovascular function were evaluated. All 3 calcium administration rates caused marked increases in both ionized and total calcium concentrations, cardiac index, stroke index, and cardiac contractility (dP/dtmax). Mean arterial pressure and right atrial pressure were unchanged; heart rate decreased markedly during calcium administration. Ionized calcium concentration remained between 54% and 57% of total calcium concentration throughout the study. We conclude that calcium gluconate can safely be administered to conscious horses at 0.1 to 0.4 mg/kg/min and that administration will result in improved cardiac function. |
Address |
Department of Veterinary Clinical Medicine, University of Illinois at Urbana-Champaign, USA |
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English |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0891-6640 |
ISBN |
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Area |
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Expedition |
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Conference |
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Notes |
PMID:8947873 |
Approved |
no |
Call Number |
refbase @ user @ |
Serial |
97 |
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Author |
Hinchcliff, K.W.; Kohn, C.W.; Geor, R.; McCutcheon, L.J.; Foreman, J.; Andrews, F.M.; Allen, A.K.; White, S.L.; Williamson, L.H.; Maykuth, P.L. |
Title |
Acid:base and serum biochemistry changes in horses competing at a modified 1 Star 3-day-event |
Type |
Journal Article |
Year |
1995 |
Publication |
Equine Veterinary Journal. Supplement |
Abbreviated Journal |
Equine Vet J Suppl |
Volume |
|
Issue |
20 |
Pages |
105-110 |
Keywords |
*Acid-Base Equilibrium; Animals; Blood Proteins/analysis; Body Water/metabolism; Carbon Dioxide/blood; Electrolytes/*blood; Female; Hematocrit/veterinary; Homeostasis; Horses/*blood/physiology; Hydrogen-Ion Concentration; Male; Physical Conditioning, Animal/*physiology |
Abstract |
We examined the effects of participation in each of 3 modifications of Day 2 of a 3-day-event on blood and serum variables indicative of hydration, acid:base status and electrolyte homeostasis of horses. Three groups of horses – 8 European (E) horses and 2 groups each of 9 North American horses performed identical Days 1 (dressage) and 3 (stadium jumping) of a 3-day-event. E horses and one group of the North American horses (TD) performed modifications of Day 2 of a 1 Star 3-day-event and the other group of North American horses (HT) performed a Horse Trial on Day 2. Jugular venous blood was collected from each horse on the morning of Day 2 before any warm-up activity, between 4 min 55 s and 5 min 15 s after Phase D and the following morning. Eight E horses, 5 TD horses and 8 HT horses completed the trials. There were few significant differences in acid:base or serum biochemistry variables detected among horses performing either 2 variations of the Speed and Endurance day of a 1 Star 3-day-event, or a conventional Horse Trial. Failure to detect differences among groups may have been related to the low statistical power associated with the small number of horses, especially in the TD group, variation in quality of horses among groups and the different times of the day at which the E horses competed. Differences detected among time points were usually common to all groups and demonstrated metabolic acidosis with a compensatory respiratory alkalosis, a reduction in total body water and cation content, and hypocalcaemia. Importantly, horses of all groups did not replenish cation, chloride, and calcium deficits after 14-18 h of recovery. |
Address |
Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Ohio State University, Columbus 43210-1089, USA |
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English |
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Series Volume |
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ISSN |
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ISBN |
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Area |
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Expedition |
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Conference |
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Notes |
PMID:8933092 |
Approved |
no |
Call Number |
Equine Behaviour @ team @ |
Serial |
3740 |
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Author |
Fulhorst, C.F.; Hardy, J.L.; Eldridge, B.F.; Chiles, R.E.; Reeves, W.C. |
Title |
Ecology of Jamestown Canyon virus (Bunyaviridae: California serogroup) in coastal California |
Type |
Journal Article |
Year |
1996 |
Publication |
The American Journal of Tropical Medicine and Hygiene |
Abbreviated Journal |
Am J Trop Med Hyg |
Volume |
55 |
Issue |
2 |
Pages |
185-189 |
Keywords |
Aedes/virology; Animals; Antibodies, Viral/blood; California/epidemiology; Cattle; Cattle Diseases/epidemiology; Deer; Dog Diseases/epidemiology; Dogs; Encephalitis Virus, California/immunology/*isolation & purification; Encephalitis, California/epidemiology/*veterinary; Female; Horse Diseases/epidemiology; Horses; Insect Vectors/virology; Lagomorpha; Male; Neutralization Tests/veterinary; Peromyscus; Rodent Diseases/epidemiology; Sigmodontinae |
Abstract |
This paper reports the first isolation of Jamestown Canyon (JC) virus from coastal California and the results of tests for antibody to JC virus in mammals living in coastal California. The virus isolation was made from a pool of 50 Aedes dorsalis females collected as adults from Morro Bay, San Luis Obispo County, California. The virus isolate was identified by two-way plaque reduction-serum dilution neutralization tests done in Vero cell cultures. Sera from the mammals were tested for antibody to JC virus by a plaque-reduction serum dilution neutralization method. A high prevalence of JC virus-specific antibody was found in horses and cattle sampled from Morro Bay. This finding is additional evidence for the presence of a virus antigenically identical or closely related to JC virus in Morro Bay and indicates that the vectors of the virus in Morro Bay feed on large mammals. A high prevalence of virus-specific antibody was also found in horses sampled from Marin and San Diego counties. This finding suggests that viruses antigenically identical or closely related to JC virus are geographically widespread in coastal California. |
Address |
School of Public Health, University of California, Berkeley, USA |
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English |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0002-9637 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
PMID:8780458 |
Approved |
no |
Call Number |
Equine Behaviour @ team @ |
Serial |
2656 |
Permanent link to this record |
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Author |
Atwill, E.R.; Mohammed, H.O.; Lopez, J.W. |
Title |
Evaluation of travel and use as a risk factor for seropositivity to Ehrlichia risticii in horses of New York state |
Type |
Journal Article |
Year |
1996 |
Publication |
American Journal of Veterinary Research |
Abbreviated Journal |
Am J Vet Res |
Volume |
57 |
Issue |
3 |
Pages |
272-277 |
Keywords |
Animals; Cross-Sectional Studies; Ehrlichiosis/epidemiology/*veterinary; Female; *Horse Diseases; Horses; Male; New York/epidemiology; Probability; Random Allocation; Risk Factors; *Travel |
Abstract |
OBJECTIVES--To determine whether mean annual frequency and destination of equine travel was associated with exposure to Ehrlichia risticii and whether these associations were modified by horses' place of residence. DESIGN--Cross-sectional study. SAMPLE POPULATION--511 equine operations containing 2,587 horses were visited in New York state from a target population of 39,000 operations. PROCEDURE--Each horse was tested for serum antibodies against E risticii, using indirect fluorescent antibody. Information on the horse's travel history, farm's management practices, and surrounding ecology was obtained by personal interview and resource maps. Statistical analyses were performed on 2 cohorts of animals: all horses enrolled in the study and horses born on the property or that resided at least 4 years on the farm. Three county-based risk regions (RR) were identified by use of cluster analysis. RESULTS--Mean seroprevalence for each of the 3 RR was 2.4 (low risk), 8.5 (moderate risk), and 18.5% (high risk) for cohort 1 and 2.5, 8.0, and 18.4% for cohort 2. Among cohorts 1 and 2, pleasure riding and breeding trips were associated with exposure to E risticii, but horse residence (low, moderate, or high RR) was an effect modifier for these associations. Among cohort 1 and stratifying the analysis according to the RR for the travel destination, trail riding at low RR and trail riding at high RR were associated with exposure. Among cohort 2 and stratifying the analysis according to the RR for the travel destination, breeding trips were associated with exposure, and strong effect modification was present for horse residence (low, moderate, or high RR). CONCLUSIONS--Only certain types of travel to specific RR were associated with higher risk of exposure to E risticii. In many instances, travel was not associated, or was associated, with a reduced risk of exposure. |
Address |
Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA |
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English |
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Edition |
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ISSN |
0002-9645 |
ISBN |
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Conference |
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Notes |
PMID:8669754 |
Approved |
no |
Call Number |
Equine Behaviour @ team @ |
Serial |
2658 |
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Author |
Ballew, R.M.; Sabelko, J.; Gruebele, M. |
Title |
Direct observation of fast protein folding: the initial collapse of apomyoglobin |
Type |
Journal Article |
Year |
1996 |
Publication |
Proceedings of the National Academy of Sciences of the United States of America |
Abbreviated Journal |
Proc. Natl. Acad. Sci. U.S.A. |
Volume |
93 |
Issue |
12 |
Pages |
5759-5764 |
Keywords |
Animals; Apoproteins/*chemistry; Circular Dichroism; Horses; Kinetics; Muscle, Skeletal/chemistry; Myoglobin/*chemistry; *Protein Folding; Spectrometry, Fluorescence; Spectrophotometry, Infrared; Temperature |
Abstract |
The rapid refolding dynamics of apomyoglobin are followed by a new temperature-jump fluorescence technique on a 15-ns to 0.5-ms time scale in vitro. The apparatus measures the protein-folding history in a single sweep in standard aqueous buffers. The earliest steps during folding to a compact state are observed and are complete in under 20 micros. Experiments on mutants and consideration of steady-state CD and fluorescence spectra indicate that the observed microsecond phase monitors assembly of an A x (H x G) helix subunit. Measurements at different viscosities indicate diffusive behavior even at low viscosities, in agreement with motions of a solvent-exposed protein during the initial collapse. |
Address |
School of Chemical Sciences and Beckman Institute for Advanced Science and Technology, University of Illinois, Urbana, 61801, USA |
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English |
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Edition |
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ISSN |
0027-8424 |
ISBN |
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Notes |
PMID:8650166 |
Approved |
no |
Call Number |
Equine Behaviour @ team @ |
Serial |
3798 |
Permanent link to this record |
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Author |
Cilnis, M.J.; Kang, W.; Weaver, S.C. |
Title |
Genetic conservation of Highlands J viruses |
Type |
Journal Article |
Year |
1996 |
Publication |
Virology |
Abbreviated Journal |
Virology |
Volume |
218 |
Issue |
2 |
Pages |
343-351 |
Keywords |
Alphavirus/*genetics; Alphavirus Infections/transmission/veterinary/virology; Amino Acid Sequence; Animals; Base Sequence; Conserved Sequence; Disease Outbreaks; Encephalitis, Viral/veterinary/virology; *Evolution, Molecular; Horses; Molecular Sequence Data; Phylogeny; RNA, Viral/genetics; Sequence Alignment; Sequence Analysis, DNA; Sequence Homology, Nucleic Acid; Turkeys; Variation (Genetics)/*genetics |
Abstract |
We studied molecular evolution of the mosquito-borne alphavirus Highlands J (HJ) virus by sequencing PCR products generated from 19 strains isolated between 1952 and 1994. Sequences of 1200 nucleotides including portions of the E1 gene and the 3' untranslated region revealed a relatively slow evolutionary rate estimated at 0.9-1.6 x 10(-4) substitutions per nucleotide per year. Phylogenetic trees indicated that all HJ viruses descended from a common ancestor and suggested the presence of one dominant lineage in North America. However, two or more minor lineages probably circulated simultaneously for periods of years to a few decades. Strains isolated from a horse suffering encephalitis, and implicated in a recent turkey outbreak, were not phylogenetically distinct from strains isolated in other locations during the same time periods. Our findings are remarkably similar to those we obtained previously for another North American alphavirus, eastern equine encephalomyelitis virus, with which Highlands J shares primary mosquito and avian hosts, geographical distribution, and ecology. These results support the hypotheses that the duration of the transmission season affects arboviral evolutionary rates and vertebrate host mobility influences genetic diversity. |
Address |
Department of Biology, University of California, San Diego, La Jolla 92093-0116, USA |
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English |
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Edition |
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ISSN |
0042-6822 |
ISBN |
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Conference |
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Notes |
PMID:8610461 |
Approved |
no |
Call Number |
Equine Behaviour @ team @ |
Serial |
2657 |
Permanent link to this record |
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Author |
Clayton, H.M. |
Title |
Comparison of the stride kinematics of the collected, working, medium and extended trot in horses |
Type |
Journal Article |
Year |
1994 |
Publication |
Equine Veterinary Journal |
Abbreviated Journal |
Equine Vet J |
Volume |
26 |
Issue |
3 |
Pages |
230-234 |
Keywords |
Analysis of Variance; Animals; Biomechanics; Female; Forelimb/anatomy & histology/physiology; Gait/*physiology; Hindlimb/anatomy & histology/physiology; Horses/anatomy & histology/*physiology; Locomotion/physiology; Male; Motion Pictures |
Abstract |
Highly-trained dressage horses were studied to test the hypothesis that stride length is altered independently of stride duration in the transitions between the collected, working, medium and extended trot. Six well-trained dressage horses were filmed at a frame rate of 150 frames/s performing the collected, working, medium and extended trots in a sand arena. Temporal, linear and angular data were extracted from the films, with 4 strides being analysed for each horse and gait type. There were no significant asymmetries between the left and rights limbs or diagonals when data from the whole group were pooled, but 3 horses showed asymmetries in one or more variables (P < 0.01). Analysis of variance and post-hoc tests indicated that the speed increased significantly (P < 0.01) from the collected (3.20 m/s) to the working (3.61 m/s) to the medium (4.47 m/s) to the extended (4.93 m/s) trot. The increases in speed were associated with a significant increase in stride length from 250 cm in the collected trot, to 273 cm in the working trot, 326 cm in the medium trot and 355 cm in the extended trot (P < 0.01). The lengthening of the stride was a result of increases between each gait type in the over-reach distance, whereas the diagonal distance was significantly longer in the extended than the collected trot only (P < 0.01). The stride duration tended to decrease as speed increased, and the difference became significant between the collected and extended trots (P < 0.01). |
Address |
Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Canada |
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English |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0425-1644 |
ISBN |
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Conference |
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Notes |
PMID:8542844 |
Approved |
no |
Call Number |
Equine Behaviour @ team @ |
Serial |
3746 |
Permanent link to this record |
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Author |
Madigan, J.E.; Kortz, G.; Murphy, C.; Rodger, L. |
Title |
Photic headshaking in the horse: 7 cases |
Type |
Journal Article |
Year |
1995 |
Publication |
Equine Veterinary Journal |
Abbreviated Journal |
Equine Vet J |
Volume |
27 |
Issue |
4 |
Pages |
306-311 |
Keywords |
Animals; Anti-Allergic Agents/therapeutic use; *Behavior, Animal; Cyproheptadine/therapeutic use; Female; *Head; Horse Diseases/drug therapy/*etiology; Horses; Light/*adverse effects; Male; Movement Disorders/drug therapy/etiology/*veterinary |
Abstract |
Seven horses with headshaking are described. No physical abnormalities were detected in any of the cases. Six of these horses had onset of clinical signs in the spring. The role of light was assessed by application of a blindfold or dark grey lens to the eyes, covering the eyes with a face mask and observing the horse in total darkness outdoors. Cessation of headshaking was observed with blindfolding (5/5 horses), night darkness outdoors (4/4 horses) and use of grey lenses (2/3 horses). Outdoor behaviour suggested efforts to avoid light in 4/4 cases. The photic sneeze in man is suggested as a putative mechanism for equine headshaking. Five of 7 horses had improvement with cyproheptadine treatment (0.3 mg/kg bwt b.i.d.). Headshaking developed within 2 calendar weeks of the same date for 3 consecutive years in one horse. Neuropharmacological alterations associated with photoperiod mechanisms leading to optic trigeminal summation are suggested as possible reasons for spring onset of headshaking. |
Address |
Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California-Davis 95616-8737, USA |
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English |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0425-1644 |
ISBN |
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Area |
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Expedition |
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Conference |
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Notes |
PMID:8536668 |
Approved |
no |
Call Number |
refbase @ user @ |
Serial |
1940 |
Permanent link to this record |