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Author Mulcahy, N.J.; Call, J.
Title How great apes perform on a modified trap-tube task Type Journal Article
Year 2006 Publication Animal Cognition Abbreviated Journal Anim. Cogn.
Volume 9 Issue 3 Pages 193-199
Keywords Animals; *Discrimination Learning; Female; Gorilla gorilla; Hominidae/*psychology; *Intelligence; Male; *Motor Skills; Pan paniscus; Pan troglodytes; Pongo pygmaeus; *Problem Solving; Species Specificity
Abstract To date, neither primates nor birds have shown clear evidence of causal knowledge when attempting to solve the trap tube task. One factor that may have contributed to mask the knowledge that subjects may have about the task is that subjects were only allowed to push the reward away from them, which is a particularly difficult action for primates in certain problem solving situations. We presented five orangutans (Pongo pygmaeus), two chimpanzees (Pan troglodytes), two bonobos (Pan paniscus), and one gorilla (Gorilla gorilla) with a modified trap tube that allowed subjects to push or rake the reward with the tool. In two additional follow-up tests, we inverted the tube 180 degrees rendering the trap nonfunctional and also presented subjects with the original task in which they were required to push the reward out of the tube. Results showed that all but one of the subjects preferred to rake the reward. Two orangutans and one chimpanzee (all of whom preferred to rake the reward), consistently avoided the trap only when it was functional but failed the original task. These findings suggest that some great apes may have some causal knowledge about the trap-tube task. Their success, however, depended on whether they were allowed to choose certain tool-using actions.
Address Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103, Leipzig, Germany. mulcahy@eva.mpg.de
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1435-9448 ISBN Medium
Area Expedition Conference
Notes (up) PMID:16612632 Approved no
Call Number Equine Behaviour @ team @ Serial 2469
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Author Balakrishnan, G.; Hu, Y.; Spiro, T.G.
Title Temperature-jump apparatus with Raman detection based on a solid-state tunable (1.80-2.05 microm) kHz optical parametric oscillator laser Type Journal Article
Year 2006 Publication Applied Spectroscopy Abbreviated Journal Appl Spectrosc
Volume 60 Issue 4 Pages 347-351
Keywords Animals; Cytochromes c/analysis; Horses; Lasers; Myoglobin/metabolism; Spectrum Analysis, Raman/*instrumentation/*methods; *Temperature
Abstract The operating characteristics of a pulsed (10 ns) tunable near-infrared (NIR) laser source are described for temperature-jump (T-jump) applications. A Q-switched Nd:YLF laser (approximately 10 ns pulses) with a 1 kHz repetition rate is used to pump a potassium titanyl arsenate (KTA) crystal-based optical parametric oscillator (OPO), producing approximately 1 mJ NIR pulses that are tunable (1.80-2.05 microm) across the 1.9 microm vibrational overtone band of water. This T-jump source has been coupled to a deep ultraviolet (UV) probe laser for Raman studies of protein dynamics. T-jumps of up to 30 degrees C, as measured via the O-H stretching Raman band of water, are readily achieved. Application to cytochrome c unfolding is demonstrated.
Address Department of Chemistry, Princeton University, Princeton, New Jersey 08544, USA
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0003-7028 ISBN Medium
Area Expedition Conference
Notes (up) PMID:16613628 Approved no
Call Number Equine Behaviour @ team @ Serial 3764
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Author Polverini, E.; Cugini, G.; Annoni, F.; Abbruzzetti, S.; Viappiani, C.; Gensch, T.
Title Molten globule formation in apomyoglobin monitored by the fluorescent probe Nile Red Type Journal Article
Year 2006 Publication Biochemistry Abbreviated Journal Biochemistry
Volume 45 Issue 16 Pages 5111-5121
Keywords Animals; Apoproteins/*chemistry/*metabolism; Binding Sites; Computer Simulation; Fluorescent Dyes/analysis; Horses; Hydrogen-Ion Concentration; Models, Molecular; Myoglobin/*chemistry/*metabolism; Oxazines/*analysis/chemistry; Protein Binding; Protein Folding; Protein Structure, Tertiary
Abstract The interaction of nile red (NR) with apomyoglobin (ApoMb) in the native (pH 7) and molten globule (pH 4) states was investigated using experimental and computational methods. NR binds to hydrophobic locations in ApoMb with higher affinity (K(d) = 25 +/- 5 microM) in the native state than in the molten globule state (K(d) = 52 +/- 5 microM). In the molten globule state, NR is located in a more hydrophobic environment. The dye does not bind to the holoprotein, suggesting that the binding site is located at the heme pocket. In addition to monitoring steady-state properties, the fluorescence emission of NR is capable of tracking submillisecond, time-resolved structural rearrangements of the protein, induced by a nanosecond pH jump. Molecular dynamics simulations were run on ApoMb at neutral pH and at pH 4. The structure obtained for the molten globule state is consistent with the experimentally available structural data. The docking of NR with the crystal structure shows that the ligand binds into the binding pocket of the heme group, with an orientation bringing the planar ring system of NR to overlap with the position of two of the heme porphyrin rings in Mb. The docking of NR with the ApoMb structure at pH 4 shows that the dye binds to the heme pocket with a slightly less favorable binding energy, in keeping with the experimental K(d) value. Under these conditions, NR is positioned in a different orientation, reaching a more hydrophobic environment in agreement with the spectroscopic data.
Address Dipartimento di Fisica, Universita degli Studi di Parma, Viale G. P. Usberti 7/A, 43100 Parma, Italy
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0006-2960 ISBN Medium
Area Expedition Conference
Notes (up) PMID:16618100 Approved no
Call Number Equine Behaviour @ team @ Serial 3763
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Author Milinovich, G.J.; Trott, D.J.; Burrell, P.C.; van Eps, A.W.; Thoefner, M.B.; Blackall, L.L.; Al Jassim, R.A.M.; Morton, J.M.; Pollitt, C.C.
Title Changes in equine hindgut bacterial populations during oligofructose-induced laminitis Type Journal Article
Year 2006 Publication Environmental Microbiology Abbreviated Journal Environ Microbiol
Volume 8 Issue 5 Pages 885-898
Keywords Animal Feed; Animals; Bacteria/classification/*isolation & purification; DNA, Bacterial/analysis; Disease Models, Animal; Feces/microbiology; Foot Diseases/etiology/microbiology/*veterinary; Horse Diseases/*etiology/metabolism/microbiology; Horses; In Situ Hybridization, Fluorescence; Intestines/*microbiology; Oligosaccharides/*administration & dosage/*metabolism; Phylogeny; Polymerase Chain Reaction; RNA, Bacterial/analysis; RNA, Ribosomal, 16S/analysis
Abstract In the horse, carbohydrate overload is thought to play an integral role in the onset of laminitis by drastically altering the profile of bacterial populations in the hindgut. The objectives of this study were to develop and validate microbial ecology methods to monitor changes in bacterial populations throughout the course of experimentally induced laminitis and to identify the predominant oligofructose-utilizing organisms. Laminitis was induced in five horses by administration of oligofructose. Faecal specimens were collected at 8 h intervals from 72 h before to 72 h after the administration of oligofructose. Hindgut microbiota able to utilize oligofructose were enumerated throughout the course of the experiment using habitat-simulating medium. Isolates were collected and representatives identified by 16S rRNA gene sequencing. The majority of these isolates collected belonged to the genus Streptococcus, 91% of which were identified as being most closely related to Streptococcus infantarius ssp. coli. Furthermore, S. infantarius ssp. coli was the predominant oligofructose-utilizing organism isolated before the onset of lameness. Fluorescence in situ hybridization probes developed to specifically target the isolated Streptococcus spp. demonstrated marked population increases between 8 and 16 h post oligofructose administration. This was followed by a rapid population decline which corresponded with a sharp decline in faecal pH and subsequently lameness at 24-32 h post oligofructose administration. This research suggests that streptococci within the Streptococcus bovis/equinus complex may be involved in the series of events which precede the onset of laminitis in the horse.
Address Australian Equine Laminitis Research Unit, School of Veterinary Science, The University of Queensland, Queensland, Australia. g.milinovich@uq.edu.au
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1462-2912 ISBN Medium
Area Expedition Conference
Notes (up) PMID:16623745 Approved no
Call Number Equine Behaviour @ team @ Serial 2625
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Author Beran, M.J.; Smith, J.D.; Redford, J.S.; Washburn, D.A.
Title Rhesus macaques (Macaca mulatta) monitor uncertainty during numerosity judgments Type Journal Article
Year 2006 Publication Journal of Experimental Psychology. Animal Behavior Processes Abbreviated Journal J Exp Psychol Anim Behav Process
Volume 32 Issue 2 Pages 111-119
Keywords Animals; *Cognition; *Judgment; Macaca mulatta/*psychology; Male; Mathematics; *Pattern Recognition, Visual; *Uncertainty
Abstract Two rhesus macaques (Macaca mulatta) judged arrays of dots on a computer screen as having more or fewer dots than a center value that was never presented in trials. After learning a center value, monkeys were given an uncertainty response that let them decline to make the numerosity judgment on that trial. Across center values (3-7), errors occurred most often for sets adjacent in numerosity to the center value. The monkeys also used the uncertainty response most frequently on these difficult trials. A 2nd experiment showed that monkeys' responses reflected numerical magnitude and not the surface-area illumination of the displays. This research shows that monkeys' uncertainty-monitoring capacity extends to the domain of numerical cognition. It also shows monkeys' use of the purest uncertainty response possible, uncontaminated by any secondary motivator.
Address Language Research Center, Georgia State University, Atlanta, 30302, USA. mjberan@yahoo.com
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0097-7403 ISBN Medium
Area Expedition Conference
Notes (up) PMID:16634654 Approved no
Call Number Equine Behaviour @ team @ Serial 2762
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Author Brannon, E.M.; Cantlon, J.F.; Terrace, H.S.
Title The role of reference points in ordinal numerical comparisons by rhesus macaques (Macaca mulatta) Type Journal Article
Year 2006 Publication Journal of Experimental Psychology. Animal Behavior Processes Abbreviated Journal J Exp Psychol Anim Behav Process
Volume 32 Issue 2 Pages 120-134
Keywords Animals; *Cognition; *Discrimination (Psychology); *Generalization (Psychology); Macaca mulatta/*psychology; Male; Mathematics; *Pattern Recognition, Visual
Abstract Two experiments examined ordinal numerical knowledge in rhesus macaques (Macaca mulatta). Experiment 1 replicated the finding (E. M. Brannon & H. S. Terrace, 2000) that monkeys trained to respond in descending numerical order (4-->3-->2-->1) did not generalize the descending rule to the novel values 5-9 in contrast to monkeys trained to respond in ascending order. Experiment 2 examined whether the failure to generalize a descending rule was due to the direction of the training sequence or to the specific values used in the training sequence. Results implicated 3 factors that characterize a monkey's numerical comparison process: Weber's law, knowledge of ordinal direction, and a comparison of each value in a test pair with the reference point established by the first value of the training sequence.
Address Center for Cognitive Neuroscience and Department of Psychological and Brain Sciences, Duke University, Durham, NC 27708, USA. brannon@duke.edu
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0097-7403 ISBN Medium
Area Expedition Conference
Notes (up) PMID:16634655 Approved no
Call Number Equine Behaviour @ team @ Serial 2761
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Author Washburn, D.A.; Smith, J.D.; Shields, W.E.
Title Rhesus monkeys (Macaca mulatta) immediately generalize the uncertain response Type Journal Article
Year 2006 Publication Journal of Experimental Psychology. Animal Behavior Processes Abbreviated Journal J Exp Psychol Anim Behav Process
Volume 32 Issue 2 Pages 185-189
Keywords Adaptation, Psychological; Animals; *Cognition; *Discrimination Learning; *Generalization (Psychology); Macaca mulatta/*psychology; Male; *Uncertainty
Abstract Rhesus monkeys (Macaca mulatta) have learned, like humans, to use an uncertain response adaptively under test conditions that create uncertainty, suggesting a metacognitive process by which human and nonhuman primates may monitor their confidence and alter their behavior accordingly. In this study, 4 rhesus monkeys generalized their use of the uncertain response, without additional training, to 2 familiar tasks (2-choice discrimination learning and mirror-image matching to sample) that predictably and demonstrably produce uncertainty. The monkeys were significantly less likely to use the uncertain response on trials in which the answer might be known. These results indicate that monkeys, like humans, know when they do not know and that they can learn to use a symbol as a generalized means for indicating their uncertainty.
Address Department of Psychology, Georgia State University, Atlanta, 30303, USA. dwashhburn@gsu.edu
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0097-7403 ISBN Medium
Area Expedition Conference
Notes (up) PMID:16634662 Approved no
Call Number Equine Behaviour @ team @ Serial 2760
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Author Aust, U.; Huber, L.
Title Picture-object recognition in pigeons: evidence of representational insight in a visual categorization task using a complementary information procedure Type Journal Article
Year 2006 Publication Journal of Experimental Psychology. Animal Behavior Processes Abbreviated Journal J Exp Psychol Anim Behav Process
Volume 32 Issue 2 Pages 190-195
Keywords Animals; Classification; *Cognition; Columbidae; *Discrimination Learning; *Form Perception; *Generalization (Psychology); Humans; Perceptual Closure; Photic Stimulation; Photography; *Recognition (Psychology)
Abstract Success in tasks requiring categorization of pictorial stimuli does not prove that a subject understands what the pictures stand for. The ability to achieve representational insight is by no means a trivial one because it exceeds mere detection of 2-D features present in both the pictorial images and their referents. So far, evidence for such an ability in nonhuman species is weak and inconclusive. Here, the authors report evidence of representational insight in pigeons. After being trained on pictures of incomplete human figures, the birds responded significantly more to pictures of the previously missing parts than to nonrepresentative stimuli, which demonstrates that they actually recognized the pictures' representational content.
Address Department for Behavior, Neurobiology and Cognition, University of Vienna, Austria. ulrike.aust@univie.ac.at
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0097-7403 ISBN Medium
Area Expedition Conference
Notes (up) PMID:16634663 Approved no
Call Number Equine Behaviour @ team @ Serial 2759
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Author Scott, L.D.
Title Living donor liver transplant--is the horse already out of the barn? Type Journal Article
Year 2006 Publication The American Journal of Gastroenterology Abbreviated Journal Am J Gastroenterol
Volume 101 Issue 4 Pages 686-688
Keywords Guidelines; Humans; Informed Consent; Liver Transplantation/*ethics; Living Donors/*ethics; Patient Selection; Risk Factors; Tissue and Organ Harvesting; Truth Disclosure
Abstract
Address Division of Gastroenterology & Hepatology, The University of Texas Medical Branch, Galveston, Texas, USA
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0002-9270 ISBN Medium
Area Expedition Conference
Notes (up) PMID:16635214 Approved no
Call Number Serial 1874
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Author Nicol, C.J.; Brown, S.N.; Glen, E.; Pope, S.J.; Short, F.J.; Warriss, P.D.; Zimmerman, P.H.; Wilkins, L.J.
Title Effects of stocking density, flock size and management on the welfare of laying hens in single-tier aviaries Type Journal Article
Year 2006 Publication British poultry science Abbreviated Journal Br Poult Sci
Volume 47 Issue 2 Pages 135-146
Keywords Animal Husbandry/*methods; *Animal Welfare; Animals; Body Constitution/*physiology; Chickens/*physiology; Crowding; Feathers; Female; *Housing, Animal/standards; Mortality; Organ Size; Oviposition/physiology; Population Density; Population Dynamics; Random Allocation
Abstract Management practices, stocking rate and flock size may affect laying hen welfare but there have been few replicated studies in commercial non-cage systems that investigate this. This study used a broad range of physical and physiological indicators to assess the welfare of hens in 36 commercial flocks. Six laying period treatments were examined with each treatment replicated 6 times. It was not possible to randomly allocate treatments to houses, so treatment and house were largely confounded. Three stocking rates were compared: 7 birds/m(2) (n = 2450), 9 birds/m(2) (n = 3150) and 12 birds/m(2) in either small (n = 2450) or large (n = 4200) flocks. In addition, at 12 birds/m(2), in both small and large flocks, birds were subjected to either standard (SM) or modified (MM) management. MM flocks had nipple drinkers and no nest-box lights. Bone strength, fracture incidence, heterophil:lymphocyte (H:L) ratio, live weight, organ weights, serum creatine, serum osmolality, muscle pH and faecal corticosterone were measured on samples of birds at the end of the rearing period and at the end of lay. During the laying period, mortality, production and integument condition were recorded at regular intervals. Birds housed at 9 birds/m(2) had higher mortality than birds housed at 12 birds/m(2) by the end of lay, but not higher than birds housed at 7 birds/m(2). Birds housed at 7 and 9 birds/m(2) had lower percent liver weight, and worse plumage condition than most of the 12 bird/m(2) treatments. Modified management tended to improve plumage condition. There were no clear effects of flock size on the welfare indicators recorded. At the end of the rearing period fracture incidence was almost negligible and H:L ratio was within a normal range. By the end of lay fracture incidence was 60% and H:L ratio was high, with no treatment effect for either measure. This, together with information on faecal corticosterone, feather loss and mortality, suggests that the welfare of birds in all treatments was relatively poor by the end of lay.
Address School of Veterinary Science, University of Bristol, Langford House, Langford BS40 5DU and ADAS Gleadthorpe, Meden Vale, Mansfield, Notts NG20 9PF, England. c.j.nicol@bristol.ac.uk
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0007-1668 ISBN Medium
Area Expedition Conference
Notes (up) PMID:16641024 Approved no
Call Number refbase @ user @ Serial 65
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