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	Author	Czerlinski, G.H.; Wagner, M.; Erickson, J.O.; Theorell, H.
	Title	Chemical relaxation studies on the system liver alcohol dehydrogenase, NADH and imidazole			Type	Journal Article
	Year	1975	Publication	Acta Chemica Scandinavica. Series B: Organic Chemistry and Biochemistry	Abbreviated Journal	Acta Chem Scand B
	Volume	29	Issue	8	Pages	797-810
	Keywords	Alcohol Oxidoreductases/metabolism; Animals; Computers; Hydrogen-Ion Concentration; Imidazoles/metabolism; Kinetics; Liver/enzymology/metabolism; Mathematics; Models, Chemical; NAD/metabolism; Time Factors
	Abstract	Several years ago, Theorell and Czerlinski conducted experiments on the system of horse liver alcohol dehydrogenase, reduced nicotinamide adenine dinucleotide and imidazole, using the first version of the temperature jump apparatus with detection of changes in fluorescence. These early experiments were repeated with improved instrumentation and confirmed the early experiments in general terms. However, the improved detection system allowed to measure a slight concentration dependence of the relaxation time of around 3 ms. Furthermore, the chemical relaxation time was smaller than the one determined earlier (by factor 2). The data were evaluated much more rigorously than before, allowing an appropriate interpretation of the results. The observed relaxation time is largely due to rate constants in an interconversion of ternary complexes, which are faster than three (of the four) dissociation rate constants, determined previously by Theorell and McKinley-McKee.1,2 This fact contributed to earlier difficulties of finding any concentration dependence. However, the binding of imidazole to the binary enzyme-coenzyme complex can be made to couple kinetically into the interconversion rate of the two ternary complexes. The observed signal derives largely from the ternary complex(es). A substantial fluorescence signal change is associated with the observed relaxation process, suggesting a relocation of the imidazole in reference to the nicotinamide moiety of the bound coenzyme. Nine models are considered with two types of coupling of pre-equilibria (none-all). Quantitative evaluations favor the model with two ternary complexes connected by an interconversion outside the four-step (bimolecular) cycle. The ternary complex outside the cycle has much higher fluorescence yield than the one inside. The interconversion equilibrium is near unity for imidazole. If it would be shifted very much to the side of the “dead-end” complex (as in isobutyramide?!), stimulating action could not take place.
	Address
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language	English	Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN	0302-4369	ISBN		Medium
	Area		Expedition		Conference
	Notes	PMID:882			Approved	no
	Call Number	refbase @ user @			Serial	3887
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	Author	Fetterman, J.G.
	Title	Dimensions of stimulus complexity			Type	Journal Article
	Year	1996	Publication	Journal of Experimental Psychology. Animal Behavior Processes	Abbreviated Journal	J Exp Psychol Anim Behav Process
	Volume	22	Issue	1	Pages	3-18
	Keywords	Animals; Behavior, Animal; Cognition; Learning; Memory; Time Factors
	Abstract	Animal learning research has increasingly used complex stimuli that approximate natural objects, events, and locations, a trend that has accompanied a resurgence of interest in the role of cognitive factors in learning. Accounts of complex stimulus control have focused mainly on cognitive mechanisms and largely ignored the contribution of stimulus information to perception and memory for complex events. It is argued here that research on animal learning stands to benefit from a more detailed consideration of the stimulus and that James Gibson's stimulus-centered theory of perception serves as a useful framework for analyses of complex stimuli. Several issues in the field of animal learning and cognition are considered from the Gibsonian perspective on stimuli, including the fundamental problem of defining the effective stimulus.
	Address	Department of Psychology, Indiana University-Purdue University, Indianapolis 46202, USA
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language	English	Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN	0097-7403	ISBN		Medium
	Area		Expedition		Conference
	Notes	PMID:8568494			Approved	no
	Call Number	Equine Behaviour @ team @			Serial	2782
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	Author	Krebs, J.R.; Clayton, N.S.; Hampton, R.R.; Shettleworth, S.J.
	Title	Effects of photoperiod on food-storing and the hippocampus in birds			Type	Journal Article
	Year	1995	Publication	Neuroreport	Abbreviated Journal	Neuroreport
	Volume	6	Issue	12	Pages	1701-1704
	Keywords	Animals; Birds; Eating/physiology; Female; Hippocampus/physiology; Light; Male; *Photoperiod; Seasons; Telencephalon/physiology; Time Factors
	Abstract	Birds that store food have a relatively large hippocampus compared to non-storing species. The hippocampus shows seasonal differences in neurogenesis and volume in black-capped chikadees (Parus atricapillus) taken from the wild at different times of year. We compared hippocampal volumes in black-capped chickadees captured at the same time but differing in food-storing behaviour because of manipulations of photoperiod in the laboratory. Differences in food-storing behaviour were not accompanied by differences in the volume of the hippocampus. Hippocampal volumes also did not differ between two groups of a non-food-storing control species, house sparrows (Passer domesticus), exposed to the same conditions as the chickadees.
	Address	Edward Grey Institute of Field Ornithology, Department of Zoology, Oxford, UK
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language	English	Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN	0959-4965	ISBN		Medium
	Area		Expedition		Conference
	Notes	PMID:8527745			Approved	no
	Call Number	refbase @ user @			Serial	378
Permanent link to this record



	Author	Domjan, M.
	Title	Selective suppression of drinking during a limited period following aversive drug treatment in rats			Type	Journal Article
	Year	1977	Publication	Journal of Experimental Psychology. Animal Behavior Processes	Abbreviated Journal	J Exp Psychol Anim Behav Process
	Volume	3	Issue	1	Pages	66-76
	Keywords	Animals; Avoidance Learning; Awareness; Conditioning, Operant; Dose-Response Relationship, Drug; Drinking Behavior/drug effects; Lithium/poisoning; Male; Osmolar Concentration; Rats; Saccharin/administration & dosage; Taste; Time Factors
	Abstract	Administration of lithium chloride disrupted the intake of flavored solutions but not water in rats. This intake suppression was directly related to the amount of lithium administered (Experiment 1), occurred with both palatable and unpalatable novel saccharin solutions (Experiment 2), but was only observed if subjects were tested starting less than 75 min. after lithium treatment (Experiment 3). Twenty-five daily exposures to saccharin did not attenuate the effect (Experiment 4). However, in saccharin-reared and vinegar-reared rats, lithium did not disrupt consumption of the solutions these subjects had access to throughout life, even though suppressions of intake were observed when these subjects were tested with novel flavors (Experiment 5). The selective disruption of drinking is interpreted as a novelty-dependent sensitization reaction to the discomfort of aversive drug administration.
	Address
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language	English	Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN	0097-7403	ISBN		Medium
	Area		Expedition		Conference
	Notes	PMID:845544			Approved	no
	Call Number	Equine Behaviour @ team @			Serial	2788
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	Author	Clayton, H.M.
	Title	Development of conditioning programs for dressage horses based on time-motion analysis of competitions			Type	Journal Article
	Year	1993	Publication	Journal of Applied Physiology (Bethesda, Md. : 1985)	Abbreviated Journal	J Appl Physiol
	Volume	74	Issue	5	Pages	2325-2329
	Keywords	Animals; Horses/physiology; Physical Conditioning, Animal; Sports; Statistics; Time Factors; Time and Motion Studies; Videotape Recording
	Abstract	The time-motion characteristics of Canadian basic- and medium-level dressage competitions are described, and the results are applied in formulating sport-specific conditioning programs. One competition was analyzed at the six levels from basic 1 to medium 3. Each test was divided into a series of sequences based on the type and speed of activity. The durations of the sequences were measured from videotapes. The basic-level tests had fewer sequences, and they were shorter in distance and duration than the medium tests (P < 0.10), but the average speed did not differ between the two levels. It is recommended that horses competing at the basic levels be conditioned using 5-min exercise periods, with short (10-s) bursts of lengthened trot and canter included at basic 2 and above. In preparation for medium-level competitions, the duration of the work periods increases to 7 min, 10- to 12-s bursts of medium or extended trot and canter are included, and transitions are performed frequently to simulate the energy expenditure in overcoming inertia.
	Address	Department of Veterinary Anatomy, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Canada
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language	English	Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN	8750-7587	ISBN		Medium
	Area		Expedition		Conference
	Notes	PMID:8335563			Approved	no
	Call Number	Equine Behaviour @ team @			Serial	3750
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	Author	McGreevy, P.D.; Cripps, P.J.; French, N.P.; Green, L.E.; Nicol, C.J.
	Title	Management factors associated with stereotypic and redirected behaviour in the thoroughbred horse			Type	Journal Article
	Year	1995	Publication	Equine veterinary journal	Abbreviated Journal	Equine Vet J
	Volume	27	Issue	2	Pages	86-91
	Keywords	Animal Husbandry/methods; Animals; Horse Diseases/psychology/therapy; Horses; Risk Factors; *Stereotyped Behavior; Time Factors
	Abstract	A greater knowledge of the effect of management factors is required to investigate the ontogeny of abnormal behaviour in the stabled horse. A postal survey of racehorse (flat) trainers yielded information about 22 yard and management factors. The relationship of the factors to the prevalence of abnormal behaviour was analysed by logistic regression. Management factors related to the time spent in the stable showed the strongest associations with stereotypic behaviour. The risk of horses performing abnormal behaviour increased: 1) as the amount of forage fell below 6.8 kg/day, 2) when bedding types other than straw were used, 3) when the total number of horses on the yard was fewer than 75, 4) in association with box designs that minimised contact between neighbouring horses, 5) when hay, rather than other types of forage, was used.
	Address	Department of Animal Health and Husbandry, School of Veterinary Science, University of Bristol, Langford, UK
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language	English	Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN	0425-1644	ISBN		Medium
	Area		Expedition		Conference
	Notes	PMID:7607155			Approved	no
	Call Number	refbase @ user @			Serial	91
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	Author	Steiner, M.
	Title	Biomechanics of tendon healing			Type	Journal Article
	Year	1982	Publication	Journal of Biomechanics	Abbreviated Journal	J Biomech
	Volume	15	Issue	12	Pages	951-958
	Keywords	Achilles Tendon/injuries; Animals; Biomechanics; Rats; Tendon Injuries/pathology/physiopathology; Tensile Strength; Time Factors; Wound Healing
	Abstract	The biomechanics of tendon healing was investigated with unsutured rat achilles tendons. After two, three, and four weeks of healing tensile parameters were assayed with a bone-muscle-tendon-bone preparation elongated to failure at a controlled physiological strain rate. In the third week of healing, stiffness, strength, and energy absorbing capacity all increased approximately 50%. These changes correlated with early fibroplasia. In the fourth week of healing, strength, energy absorbing capacity and elongation to failure all increased relatively more than stiffness. Histologically, larger fibers with better longitudinal alignment developed during this period. At the end of four weeks the tendon's strength was approximately 25% of normal. To summarize, the return of stiffness in a healing tendon preparation correlated with the presence of fibroplasia and the return of other tensile parameters was a function of the amount and organization of the fibroplasia.
	Address
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language	English	Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN	0021-9290	ISBN		Medium
	Area		Expedition		Conference
	Notes	PMID:7166555			Approved	no
	Call Number	Equine Behaviour @ team @			Serial	4448
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	Author	Donnelly, J.; Phipps, L.P.; Watkins, K.L.
	Title	Evidence of maternal antibodies to Babesia equi and B caballi in foals of seropositive mares			Type	Journal Article
	Year	1982	Publication	Equine Veterinary Journal	Abbreviated Journal	Equine Vet J
	Volume	14	Issue	2	Pages	126-128
	Keywords	Animals; Antibodies/analysis; Babesia/immunology; Complement Fixation Tests; Female; Horses/*immunology; Immunity, Maternally-Acquired; Male; Time Factors
	Abstract
	Address
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language	English	Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN	0425-1644	ISBN		Medium
	Area		Expedition		Conference
	Notes	PMID:7084196			Approved	no
	Call Number	Equine Behaviour @ team @			Serial	2280
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	Author	Hinson, R.E.
	Title	Effects of UCS preexposure on excitatory and inhibitory rabbit eyelid conditioning: an associative effect of conditioned contextual stimuli			Type	Journal Article
	Year	1982	Publication	Journal of Experimental Psychology. Animal Behavior Processes	Abbreviated Journal	J Exp Psychol Anim Behav Process
	Volume	8	Issue	1	Pages	49-61
	Keywords	Animals; Association Learning; Cognition; Conditioning, Eyelid; Inhibition (Psychology); Practice (Psychology); Rabbits; Reaction Time
	Abstract	Preconditioning experience with the unconditional stimulus (UCS) retards subsequent excitatory conditioning. Three experiments demonstrated that this UCS retardation effect is attenuated by associative manipulations of contextual stimuli of the UCS preexposure environment. The UCS retardation effect was reduced by (a) altering contextual stimuli between preexposure and conditioning (Experiment 1), (b) latently inhibiting contextual stimuli prior to UCS preexposure (Experiment 2), and (c) extinguishing contextual stimuli subsequent to UCS preexposure (Experiment 3). Although UCS preexposure retarded excitatory conditioning, the results of Experiment 4 demonstrated that UCS preexposure facilitated inhibitory conditioning. These results indicate that an association between contextual stimuli and the preexposed UCS contributes to the effects of preconditioning UCS experience on subsequent learning.
	Address
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language	English	Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN	0097-7403	ISBN		Medium
	Area		Expedition		Conference
	Notes	PMID:7057144			Approved	no
	Call Number	Equine Behaviour @ team @			Serial	2787
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	Author	Hogan, D.E.; Zentall, T.R.; Pace, G.
	Title	Control of pigeons' matching-to-sample performance by differential sample response requirements			Type	Journal Article
	Year	1983	Publication	The American journal of psychology	Abbreviated Journal	Am J Psychol
	Volume	96	Issue	1	Pages	37-49
	Keywords	Animals; Association; Color Perception; Columbidae; Cues; Discrimination Learning; Reinforcement Schedule; Time Factors
	Abstract	Pigeons were trained on a matching-to-sample task in which sample hue and required sample-specific observing behavior provided redundant, relevant cues for correct choices. On trials that involved red and yellow hues as comparison stimuli, a fixed-ratio 16 schedule (FR 16) was required to illuminate the comparisons when the sample was red, and a differential-reinforcement-of-low-rates 3-sec schedule (DRL 3-sec) was required when the sample was yellow. On trials involving blue and green hues as comparison stimuli, an FR 16 schedule was required when the sample was blue and a DRL 3-sec schedule was required when the sample was green. For some pigeons, a 0-sec delay intervened between sample offset and comparison onset, whereas other pigeons experienced a random mixture of 0-sec and 2-sec delay trials. Test trial performance at 0-sec delay indicated that sample-specific behavior controlled choice performance considerably more than sample hue did. Test performance was independent of whether original training involved all 0-sec delay trials or a mixture of 0-sec and 2-sec delays. Sample-specific observing response requirements appear to facilitate pigeons' matching-to-sample performance by strengthening associations between the observing response and correct choice.
	Address
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language	English	Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN	0002-9556	ISBN		Medium
	Area		Expedition		Conference
	Notes	PMID:6859346			Approved	no
	Call Number	refbase @ user @			Serial	265
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