Records |
Author |
Alexander, F. |
Title |
The effect of some anti-diarrhoeal drugs on intestinal transit and faecal excretion of water and electrolytes in the horse |
Type |
Journal Article |
Year |
1978 |
Publication |
Equine veterinary journal |
Abbreviated Journal |
Equine Vet J |
Volume |
10 |
Issue |
4 |
Pages |
229-234 |
Keywords |
Animals; Antidiarrheals/*pharmacology; Atropine/pharmacology; Electrolytes/*analysis/urine; Feces/*analysis; Gastrointestinal Motility/*drug effects; Horses/*metabolism/physiology; Loperamide/pharmacology; Male; Meperidine/pharmacology; Morphine/pharmacology; Opium/pharmacology; Water/*analysis |
Abstract |
The effect of morphine, Tinct. opii, loperamide, pethidine and atropine on intestinal transit and the faecal and urinary excretion of water and electrolytes was studied in ponies. The rate of passage of a particulate marker was slowed by morphine, hastened then slowed by loperamide and Tinct. opii, and hastened by atropine. The liquid marker was slowed by Tinct. opii and hastened then slowed by the other drugs. Only loperamide decreased the faecal sodium excretion. This drug also decreased faecal water and weight; it appeared worthy of clinical trial in diarrhoea. Tinct. opii decreased by morphine, pethidine and atropine increased faecal water. |
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ISSN |
0425-1644 |
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PMID:738263 |
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no |
Call Number |
refbase @ user @ |
Serial |
110 |
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Author |
Alexander, F. |
Title |
The effect of diuretics on the faecal excretion of water and electrolytes in horses |
Type |
Journal Article |
Year |
1977 |
Publication |
British journal of pharmacology |
Abbreviated Journal |
Br J Pharmacol |
Volume |
60 |
Issue |
4 |
Pages |
589-593 |
Keywords |
Animals; Body Water/*metabolism; Chlorides/metabolism; Electrolytes/*metabolism; Feces/*analysis; Furosemide/*pharmacology; Horses; Hydrochlorothiazide/*pharmacology; Male; Potassium/metabolism; Sodium/metabolism; Time Factors |
Abstract |
1. The effect on plasma, urinary and faecal electrolytes of frusemide and hydrochlorthiazide was measured in ponies, mean weight 180 kg. 2. The rapid loss in urine of large quantities of sodium had only a small effect on plasma sodium concentration. 3. Faecal sodium excretion was increased substantially after the administration of frusemide. 4. Frusemide increased faecal potassium during the 48 h following administration and faecal water in the 24/48 h period. It also produced a hypopotassaemia. 5. Hydrochlorthiazide increased faecal chloride during the 24 h after administration. 6. Frusemide increased the intestinal transit time of both liquid (polyethylene glycol) and particulate (Cr2O3) markers. |
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0007-1188 |
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Notes |
PMID:907872 |
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no |
Call Number |
refbase @ user @ |
Serial |
111 |
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Author |
Alexander, F.; Collett, R.A. |
Title |
Proceedings: Some observations on the pharmacokinetics of trimethoprim in the horse |
Type |
Journal Article |
Year |
1974 |
Publication |
British journal of pharmacology |
Abbreviated Journal |
Br J Pharmacol |
Volume |
52 |
Issue |
1 |
Pages |
142p |
Keywords |
Animals; Half-Life; Horses/*metabolism; Kinetics; Trimethoprim/*metabolism |
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0007-1188 |
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Notes |
PMID:4451793 |
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no |
Call Number |
refbase @ user @ |
Serial |
112 |
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Author |
Alexander, F.; Collett, R.A. |
Title |
Pethidine in the horse |
Type |
Journal Article |
Year |
1974 |
Publication |
Research in veterinary science |
Abbreviated Journal |
Res Vet Sci |
Volume |
17 |
Issue |
1 |
Pages |
136-137 |
Keywords |
Animals; Half-Life; Horses/*metabolism; Injections, Intravenous/veterinary; Male; Meperidine/administration & dosage/analysis/*metabolism/pharmacology |
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ISSN |
0034-5288 |
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Notes |
PMID:4421117 |
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no |
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refbase @ user @ |
Serial |
113 |
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Author |
Alexander, F. |
Title |
Multiple fistulation of the horse's large intestine |
Type |
Journal Article |
Year |
1970 |
Publication |
The British veterinary journal |
Abbreviated Journal |
Br. Vet. J. |
Volume |
126 |
Issue |
11 |
Pages |
604-606 |
Keywords |
Animals; Cecum/physiology; Colon/physiology; Horses/*physiology; Intestinal Fistula; Intestine, Large/*physiology; *Intubation, Gastrointestinal; Methods |
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ISSN |
0007-1935 |
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Notes |
PMID:5492494 |
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no |
Call Number |
refbase @ user @ |
Serial |
115 |
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Author |
Alexander, F.; Davies, M.E. |
Title |
Studies on vitamin B12 in the horse |
Type |
Journal Article |
Year |
1969 |
Publication |
The British veterinary journal |
Abbreviated Journal |
Br. Vet. J. |
Volume |
125 |
Issue |
4 |
Pages |
169-176 |
Keywords |
Animals; Biological Assay; Cattle; Chickens; Feces/analysis; Horses/*metabolism; Humans; Lactobacillus/metabolism; Rabbits; Rats; Sheep; Urine/analysis; Vitamin B 12/*analysis |
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English |
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Series Issue |
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Edition |
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ISSN |
0007-1935 |
ISBN |
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Notes |
PMID:5814055 |
Approved |
no |
Call Number |
refbase @ user @ |
Serial |
116 |
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Author |
Alexander, F.; Nicholson, J.D. |
Title |
The blood and saliva clearances of phenobarbitone and pentobarbitone in the horse |
Type |
Journal Article |
Year |
1968 |
Publication |
Biochemical pharmacology |
Abbreviated Journal |
Biochem Pharmacol |
Volume |
17 |
Issue |
2 |
Pages |
203-210 |
Keywords |
Animals; Female; *Horses; Injections, Intravenous; Male; Metabolic Clearance Rate; Pentobarbital/blood/*metabolism; Phenobarbital/blood/*metabolism; Protein Binding; *Saliva; Time Factors |
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ISSN |
0006-2952 |
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Notes |
PMID:5647047 |
Approved |
no |
Call Number |
refbase @ user @ |
Serial |
117 |
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Author |
Alexander, F.; Horner, M.W.; Moss, M.S. |
Title |
The salivary secretion and clearance in the horse of chloral hydrate and its metabolites |
Type |
Journal Article |
Year |
1967 |
Publication |
Biochemical pharmacology |
Abbreviated Journal |
Biochem Pharmacol |
Volume |
16 |
Issue |
7 |
Pages |
1305-1311 |
Keywords |
Animals; Chloral Hydrate/blood/*metabolism/urine; Chromatography, Gas; Ethanol/blood/urine; Horses; Male; Parotid Gland/metabolism; Saliva/*analysis; Trichloroacetic Acid/blood/urine |
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0006-2952 |
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Notes |
PMID:6053598 |
Approved |
no |
Call Number |
refbase @ user @ |
Serial |
118 |
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Author |
Alexander, F. |
Title |
A study of parotid salivation in the horse |
Type |
Journal Article |
Year |
1966 |
Publication |
The Journal of physiology |
Abbreviated Journal |
J Physiol |
Volume |
184 |
Issue |
3 |
Pages |
646-656 |
Keywords |
Animals; Atropine/*pharmacology; Bicarbonates/metabolism; Calcium/metabolism; Chlorides/metabolism; Horses; Mastication/*physiology; Parotid Gland/*physiology; Pilocarpine/*pharmacology; Potassium/metabolism; Salivation/*drug effects; Sodium/metabolism; Tetracaine/*pharmacology |
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0022-3751 |
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PMID:5963737 |
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refbase @ user @ |
Serial |
119 |
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Author |
Alexander, F.; Chowdhury, A.K. |
Title |
Enzymes in the ileal juice of the horse |
Type |
Journal Article |
Year |
1958 |
Publication |
Nature |
Abbreviated Journal |
Nature |
Volume |
181 |
Issue |
4603 |
Pages |
190 |
Keywords |
*Enzymes; *Horses; Ileum/*metabolism; *Enzymes; *Horses; *ILEUM/metabolism |
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ISSN |
0028-0836 |
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Notes |
PMID:13504127 |
Approved |
no |
Call Number |
refbase @ user @ |
Serial |
121 |
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