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Author Pinchbeck, G.L.; Clegg, P.D.; Proudman, C.J.; Morgan, K.L.; French, N.R.
Title Whip use and race progress are associated with horse falls in hurdle and steeplechase racing in the UK Type Journal Article
Year 2004 Publication Equine Veterinary Journal Abbreviated Journal Equine Vet J
Volume 36 Issue 5 Pages 384-389
Keywords Accidental Falls/*statistics & numerical data; Animals; Athletic Injuries/epidemiology/etiology/*veterinary; Case-Control Studies; Cohort Studies; Great Britain/epidemiology; Horses/*injuries; Logistic Models; Odds Ratio; Retrospective Studies; Risk Factors; Running/statistics & numerical data; Sports; Videotape Recording
Abstract REASONS FOR PERFORMING STUDY: Falls during racing present a risk of injury to both horse and jockey and a risk of fatality to horses. OBJECTIVES: To use video recordings of races to describe the circumstances surrounding horse falls at hurdle and steeplechase fences and to identify and quantify within-race risk factors for horse falls in National Hunt racing in the UK. METHODS: A retrospective, matched, nested case-control study using video recordings of races was conducted on 6 UK racecourses. Cases and controls were matched on both race type and jump number at which the fall occurred. Conditional logistic regression analysis was used to examine the univariable and multivariable relationship between predictor variables and the risk of falling. RESULTS: The risk of falling was significantly associated with whip use and race progress. Horses which were being whipped and progressing through the race were at greater than 7 times the risk of falling compared to horses which were not being whipped and which had no change in position or lost position through the field. CONCLUSIONS: This study has identified whip use and the position of the horse with respect to others in the field as potential risk factors for horse falls. POTENTIAL RELEVANCE: If these findings are confirmed by the use of intervention trials (e.g. with whip-free or restricted whip use races), modifications could be introduced which would reduce the frequency of horse falls, leading to improved equine welfare.
Address Epidemiology Group, Department of Veterinary Clinical Science, University of Liverpool, Leahurst, Neston, Wirral CH64 7TE, UK
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0425-1644 ISBN Medium (up)
Area Expedition Conference
Notes PMID:15253077 Approved no
Call Number Equine Behaviour @ team @ Serial 3659
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Author Bobbert, M.F.; Alvarez, C.B.G.; van Weeren, P.R.; Roepstorff, L.; Weishaupt, M.A.
Title Validation of vertical ground reaction forces on individual limbs calculated from kinematics of horse locomotion Type Journal Article
Year 2007 Publication The Journal of Experimental Biology Abbreviated Journal J Exp Biol
Volume 210 Issue Pt 11 Pages 1885-1896
Keywords
Abstract The purpose of this study was to determine whether individual limb forces could be calculated accurately from kinematics of trotting and walking horses. We collected kinematic data and measured vertical ground reaction forces on the individual limbs of seven Warmblood dressage horses, trotting at 3.4 m s(-1) and walking at 1.6 m s(-1) on a treadmill. First, using a segmental model, we calculated from kinematics the total ground reaction force vector and its moment arm relative to each of the hoofs. Second, for phases in which the body was supported by only two limbs, we calculated the individual reaction forces on these limbs. Third, we assumed that the distal limbs operated as linear springs, and determined their force-length relationships using calculated individual limb forces at trot. Finally, we calculated individual limb force-time histories from distal limb lengths. A good correspondence was obtained between calculated and measured individual limb forces. At trot, the average peak vertical reaction force on the forelimb was calculated to be 11.5+/-0.9 N kg(-1) and measured to be 11.7+/-0.9 N kg(-1), and for the hindlimb these values were 9.8+/-0.7 N kg(-1) and 10.0+/-0.6 N kg(-1), respectively. At walk, the average peak vertical reaction force on the forelimb was calculated to be 6.9+/-0.5 N kg(-1) and measured to be 7.1+/-0.3 N kg(-1), and for the hindlimb these values were 4.8+/-0.5 N kg(-1) and 4.7+/-0.3 N kg(-1), respectively. It was concluded that the proposed method of calculating individual limb reaction forces is sufficiently accurate to detect changes in loading reported in the literature for mild to moderate lameness at trot.
Address Institute for Fundamental and Clinical Human Movement Sciences, Vrije Universiteit, van der Boechorstraat 9, NL-1081 BT Amsterdam, The Netherlands
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0022-0949 ISBN Medium (up)
Area Expedition Conference
Notes PMID:17515415 Approved no
Call Number Equine Behaviour @ team @ Serial 3700
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Author Cayado, P.; Munoz-Escassi, B.; Dominguez, C.; Manley, W.; Olabarri, B.; Sanchez de la Muela, M.; Castejon, F.; Maranon, G.; Vara, E.
Title Hormone response to training and competition in athletic horses Type Journal Article
Year 2006 Publication Equine Veterinary Journal. Supplement Abbreviated Journal Equine Vet J Suppl
Volume Issue 36 Pages 274-278
Keywords Adrenocorticotropic Hormone/*blood; Animals; Case-Control Studies; *Horses/blood/physiology/psychology; Hydrocortisone/*blood; Physical Conditioning, Animal/*physiology; Sports; *Stress, Psychological
Abstract REASONS FOR PERFORMING STUDY: It is recognised that the amount of psychological stress that an animal encounters determines the degree of response of the hypothalamic-pituitary-adrenal (HPA) axis. In human athletes, the added emotive stress of competition is an important element in the adrenal response. The aim of this study was to examine the effect of show-jumping as well as dressage on stress levels by comparing horses' stress response at a horse show compared to their familiar home. METHODS: Fifty-one horses involved in competition were used. EDTA blood samples were collected before exercise, upon arrived to the schooling area (control), and k over a jump or dressage course. After sampling, plasma was separated and stored at -80 degrees C until determinations of cortisol and ACTH were performed. Fourteen healthy horses not involved in competition were used as control group. RESULTS: Competition induced a significant increase in cortisol and ACTH responses in both, jumping and dressage horses and this effect was more apparent in dressage horses. When horses were most experienced, cortisol and ACTH responses were much lower. CONCLUSION: This study shows that competition elicits a classic physiological stress response in horses and that different training programmes induce different responses. It suggests that horses involved in competition can provide a good model to study the exercise-induced stress response.
Address Hospital SL., Madrid, Spain
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN Medium (up)
Area Expedition Conference
Notes PMID:17402431 Approved no
Call Number Equine Behaviour @ team @ Serial 3705
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Author Barnes, H.G.; Tucker, R.L.; Grant, B.D.; Roberts, G.D.; Prades, M.
Title Lag screw stabilization of a cervical vertebral fracture by use of computed tomography in a horse Type Journal Article
Year 1995 Publication Journal of the American Veterinary Medical Association Abbreviated Journal J Am Vet Med Assoc
Volume 206 Issue 2 Pages 221-223
Keywords Animals; Bone Screws/*veterinary; Cervical Vertebrae/*injuries/surgery; Fracture Fixation, Internal/methods/*veterinary; Horses/*injuries/surgery; Male; Spinal Fractures/surgery/*veterinary; Tomography, X-Ray Computed/veterinary
Abstract A traumatic fracture of C2 was diagnosed radiographically in a 1-year-old German Warm-blood stallion. Fracture configuration was difficult to see on survey radiographs. Computed tomography yielded a more accurate assessment of the fracture and facilitated fracture repair with cortical lag screws. Precise screw placement, to avoid spinal cord damage, was obtained by use of computed tomography. Follow-up radiography revealed normal bone healing, and the horse was in dressage schooling 24 months after surgery.
Address Department of Clinical Sciences, College of Veterinary Medicine, Washington State University, Pullman 99164-6610
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0003-1488 ISBN Medium (up)
Area Expedition Conference
Notes PMID:7751226 Approved no
Call Number Equine Behaviour @ team @ Serial 3744
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Author Boden, L.A.; Anderson, G.A.; Charles, J.A.; Morgan, K.L.; Morton, J.M.; Parkin, T.D.H.; Slocombe, R.F.; Clarke, A.F.
Title Risk of fatality and causes of death of Thoroughbred horses associated with racing in Victoria, Australia: 1989-2004 Type Journal Article
Year 2006 Publication Equine Veterinary Journal Abbreviated Journal Equine Vet J
Volume 38 Issue 4 Pages 312-318
Keywords Animals; Athletic Injuries/epidemiology/mortality/*veterinary; *Cause of Death; Female; *Floors and Floorcoverings; Horses/*injuries; Male; Physical Conditioning, Animal/*adverse effects; Risk Factors; Running/injuries; Safety; Sports; Victoria
Abstract REASONS FOR PERFORMING STUDY: Determining the risk of fatality of Thoroughbred horses while racing is essential to assess the impact of intervention measures designed to minimise such fatalities. OBJECTIVES: To measure the risk of racehorse fatality in jump and flat starts on racecourses in Victoria, Australia, over a 15 year period and to determine proportional mortality rates for specific causes of death. METHODS: All fatalities of Thoroughbred horses that occurred during or within 24 h of a race were identified from a database. The risk of a start resulting in a racehorse fatality in all races and within flat and jump races, proportional mortality rates, population attributable risk, population attributable fraction and risk ratios were calculated along with 95% confidence intervals. Poisson regression was also performed to estimate risk ratios. RESULTS: There were 514 fatalities over the 15 year period; 316 in flat races and 198 in jump races. The risk of fatality was 0.44 per 1000 flat starts and 8.3 per 1000 jump starts (18.9 x greater). The risk of fatality on city tracks was 1.1 per 1000 starts whereas on country tracks it was 0.57 per 1000 starts. Of the 316 fatalities in flat races, 73.4% were due to limb injury, 2.5% to cranial or vertebral injury and 19.0% were sudden deaths. Of the 198 fatalities in jump races, 68.7% were due to limb injury, 16.2% to cranial or vertebral injury and 3.5% were sudden deaths. The risk of fatality in flat starts increased between 1989 and 2004 but the risk in jump starts remained unchanged over the 15 year period. CONCLUSIONS: The risk of fatality in flat starts was lower in Victoria than North America and the UK but the risk in jump starts was greater. Catastrophic limb injury was the major reason for racehorse fatality in Victoria but there was a larger percentage of sudden deaths than has been reported overseas. The risk of fatality in jump starts remained constant over the study period despite jump racing reviews that recommended changes to hurdle and steeple races to improve safety. POTENTIAL RELEVANCE: This study provides important benchmarks for the racing industry to monitor racetrack fatalities and evaluate intervention strategies.
Address Department of Veterinary Science, The University of Melbourne, Werribee, Victoria, Australia
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0425-1644 ISBN Medium (up)
Area Expedition Conference
Notes PMID:16866197 Approved no
Call Number Equine Behaviour @ team @ Serial 3761
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Author Polverini, E.; Cugini, G.; Annoni, F.; Abbruzzetti, S.; Viappiani, C.; Gensch, T.
Title Molten globule formation in apomyoglobin monitored by the fluorescent probe Nile Red Type Journal Article
Year 2006 Publication Biochemistry Abbreviated Journal Biochemistry
Volume 45 Issue 16 Pages 5111-5121
Keywords Animals; Apoproteins/*chemistry/*metabolism; Binding Sites; Computer Simulation; Fluorescent Dyes/analysis; Horses; Hydrogen-Ion Concentration; Models, Molecular; Myoglobin/*chemistry/*metabolism; Oxazines/*analysis/chemistry; Protein Binding; Protein Folding; Protein Structure, Tertiary
Abstract The interaction of nile red (NR) with apomyoglobin (ApoMb) in the native (pH 7) and molten globule (pH 4) states was investigated using experimental and computational methods. NR binds to hydrophobic locations in ApoMb with higher affinity (K(d) = 25 +/- 5 microM) in the native state than in the molten globule state (K(d) = 52 +/- 5 microM). In the molten globule state, NR is located in a more hydrophobic environment. The dye does not bind to the holoprotein, suggesting that the binding site is located at the heme pocket. In addition to monitoring steady-state properties, the fluorescence emission of NR is capable of tracking submillisecond, time-resolved structural rearrangements of the protein, induced by a nanosecond pH jump. Molecular dynamics simulations were run on ApoMb at neutral pH and at pH 4. The structure obtained for the molten globule state is consistent with the experimentally available structural data. The docking of NR with the crystal structure shows that the ligand binds into the binding pocket of the heme group, with an orientation bringing the planar ring system of NR to overlap with the position of two of the heme porphyrin rings in Mb. The docking of NR with the ApoMb structure at pH 4 shows that the dye binds to the heme pocket with a slightly less favorable binding energy, in keeping with the experimental K(d) value. Under these conditions, NR is positioned in a different orientation, reaching a more hydrophobic environment in agreement with the spectroscopic data.
Address Dipartimento di Fisica, Universita degli Studi di Parma, Viale G. P. Usberti 7/A, 43100 Parma, Italy
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0006-2960 ISBN Medium (up)
Area Expedition Conference
Notes PMID:16618100 Approved no
Call Number Equine Behaviour @ team @ Serial 3763
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Author Hurn, S.D.; Turner, A.G.
Title Ophthalmic examination findings of Thoroughbred racehorses in Australia Type Journal Article
Year 2006 Publication Veterinary Ophthalmology Abbreviated Journal Vet Ophthalmol
Volume 9 Issue 2 Pages 95-100
Keywords Animals; Cataract/epidemiology/veterinary; Diagnostic Techniques, Ophthalmological/veterinary; Eye Diseases/diagnosis/epidemiology/*veterinary; Female; Horse Diseases/diagnosis/*epidemiology; Horses; Male; Prevalence; Victoria/epidemiology
Abstract OBJECTIVE: To record the prevalence and document the types of eye disease in population of Thoroughbred racehorses in Victoria, Australia. DESIGN: Prospective study. ANIMALS: Two hundred four Thoroughbred racehorses. PROCEDURE: All horses and both eyes were examined at four metropolitan and two country racing stable complexes. Ophthalmic exam was performed following dark adaptation with a transilluminator, biomicroscope, and direct ophthalmoscope. Intraocular pressures were measured when indicated. Both pupils were dilated with tropicamide when indicated. RESULTS: One hundred eighty-two (89.2%) flat-racing and 22 (10.8%) jump-racing (hurdle or steeple) horses were examined. Age range: 2-9 years (mean 3.7 years, median 3); 97 (47.5%) male-neuter, 74 (36. 3%) female, 33 (16.2%) male. Potential vision-threatening eye disease was present in 15 (7.4%) different horses: complete lenticular cataracts 3, posterior lens luxation and cataract 1, large peripapillary 'butterfly' inactive lesions 3, large peripapillary 'butterfly' active lesions 2, peripapillary focal inactive 'bullet hole' chorioretinal lesions (> 20) 5, optic nerve atrophy 1. Non-vision threatening eye disease was present in 117 (57.4%) different horses, involving one or more ocular structures: lower eyelid scars 3; periocular fibropapillomatous disease 1; third eyelid squamous cell carcinoma 1; corneal scars 6; corneal band opacity 2; anterior iris synechia 1; developmental cataracts 36 (17.2%); peripapillary focal inactive 'bullet hole' chorioretinal lesions (< 20) 103 (50.0%); linear peripapillary hyperpigmentation bands 16 (7.9%). Unusual variations of normal ocular anatomy and colobomata was recorded in 11 (5.4%) different horses: granular iridica hypoplasia 3, granular iridica hyperplasia 2, multilobular granular iridica cyst 1, microcornea 1, hyaloid remnant 1, rotated optic nerve head 1, coloboma of the lens 1, atypical coloboma of the retina 1. CONCLUSIONS: This survey demonstrates that the prevalence of vision-threatening eye disease in racing horses may be greater than previously perceived, and highlights the importance of ocular examination within any routine physical examination of horses.
Address All Animal Eye Services, Mount Waverley, Victoria, Australia. sdhurn@bigpond.com
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1463-5216 ISBN Medium (up)
Area Expedition Conference
Notes PMID:16497233 Approved no
Call Number Equine Behaviour @ team @ Serial 3766
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Author Balendra, G.; Turner, M.; McCrory, P.; Halley, W.
Title Injuries in amateur horse racing (point to point racing) in Great Britain and Ireland during 1993-2006 Type Journal Article
Year 2007 Publication British Journal of Sports Medicine Abbreviated Journal Br J Sports Med
Volume 41 Issue 3 Pages 162-166
Keywords
Abstract OBJECTIVES: To provide a breakdown of injury incidence from amateur jump racing (also known as point to point racing) in Great Britain and Ireland during 1993-2006 and to compare the injury epidemiology with professional horse racing in Great Britain, Ireland and France. DESIGN: Retrospective review. SETTING: Great Britain and Ireland. PARTICIPANTS: Amateur jockeys. MAIN OUTCOME MEASURES: Injury rates. RESULTS: Injury data suggest that point to point racing is more dangerous from an injury point of view than professional jump racing, which has previously been shown to be more dangerous than flat racing. Amateur jockeys have more falls than their professional counterparts, and this in turn puts them at greater risk of sustaining more serious injuries. CONCLUSIONS: Amateur (point to point) jockeys represent a sporting population that previously has been little studied. They represent a group at high risk of injury, and hence formal injury surveillance tracking and counter measures for injury prevention are recommended.
Address University of Melbourne, Melbourne, Victoria, Australia
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1473-0480 ISBN Medium (up)
Area Expedition Conference
Notes PMID:17138629 Approved no
Call Number refbase @ user @ Serial 3821
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Author Pinchbeck, G.L.; Clegg, P.D.; Proudman, C.J.; Morgan, K.L.; French, N.P.
Title Case-control investigation of the factors affecting the risk of horses falling during steeplechase racing in the UK Type Journal Article
Year 2004 Publication The Veterinary Record Abbreviated Journal Vet. Rec.
Volume 155 Issue 1 Pages 11-15
Keywords Accidental Falls/*prevention & control/*statistics & numerical data; Animals; Athletic Injuries/epidemiology/etiology/prevention & control/*veterinary; Case-Control Studies; England/epidemiology; Horses/*injuries; Risk Factors; Running/*injuries
Abstract A concurrent case-control study of 12 UK racecourses was made between March 1, 2000, and August 31, 2001, to identify and quantify the factors associated with the risk of horses falling in steeplechase races. Cases were defined as a jumping effort at a steeplechase fence that resulted in a fall and controls were defined as a successful jumping effort over any steeplechase fence at any of the 12 racecourses within 14 days before or after the case fall. Information on the horse, the jockey and the race were collected and all the fences on all the courses were surveyed. Conditional logistic regression was used to examine the relationships between the predictor variables and the risk of falling. There was one fall per 254 jumping efforts. The risk of a horse falling decreased the more times it had raced on a particular racecourse. The number of fences, the distance from the previous fence and the nature of the previous fence also affected the risk of falling. If the previous fence was a water jump the risk of falling increased; fences that were sited on flat or slight uphill gradients (up to approximately 1 in 25) were associated with a lower risk of horses falling than downhill fences, and higher takeoff boards were associated with a higher risk of falling.
Address Department of Veterinary Clinical Science, University of Liverpool, Leahurst, Neston CH64 7TE
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0042-4900 ISBN Medium (up)
Area Expedition Conference
Notes PMID:15264483 Approved no
Call Number Equine Behaviour @ team @ Serial 3773
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Author Hoang, L.; Maity, H.; Krishna, M.M.G.; Lin, Y.; Englander, S.W.
Title Folding units govern the cytochrome c alkaline transition Type Journal Article
Year 2003 Publication Journal of Molecular Biology Abbreviated Journal J Mol Biol
Volume 331 Issue 1 Pages 37-43
Keywords Animals; Cytochrome c Group/*chemistry; Horses; Hydrogen/chemistry; Hydrogen-Ion Concentration; Kinetics; Models, Molecular; *Protein Folding; Protein Structure, Tertiary; Spectrum Analysis; Titrimetry
Abstract The alkaline transition of cytochrome c is a model for protein structural switching in which the normal heme ligand is replaced by another group. Stopped flow data following a jump to high pH detect two slow kinetic phases, suggesting two rate-limiting structure changes. Results described here indicate that these events are controlled by the same structural unfolding reactions that account for the first two steps in the reversible unfolding pathway of cytochrome c. These and other results show that the cooperative folding-unfolding behavior of protein foldons can account for a variety of functional activities in addition to determining folding pathways.
Address Department of Biochemistry and Biophysics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104-6059, USA. lhoang@mail.upenn.edu
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0022-2836 ISBN Medium (up)
Area Expedition Conference
Notes PMID:12875834 Approved no
Call Number Equine Behaviour @ team @ Serial 3781
Permanent link to this record