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Author |
Griebenow, K.; Klibanov, A.M. |
Title |
Lyophilization-induced reversible changes in the secondary structure of proteins |
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Journal Article |
Year |
1995 |
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Proc Natl Acad Sci USA |
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92 |
Issue |
24 |
Pages |
10969-10976 |
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Changes in the secondary structure of some dozen different proteins upon lyophilization of their aqueous solutions have been investigated by means of Fourier-transform infrared spectroscopy in the amide III band region. Dehydration markedly (but reversibly) alters the secondary structure of all the proteins studied, as revealed by both the quantitative analysis of the second derivative spectra and the Gaussian curve fitting of the original infrared spectra. Lyophilization substantially increases the beta-sheet content and lowers the alpha-helix content of all proteins. In all but one case, proteins become more ordered upon lyophilization. |
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Equine Behaviour @ team @ |
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6519 |
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Boissy, A. |
Title |
Fear and Fearfulness in Animals |
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Journal Article |
Year |
1995 |
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The Quarterly Review of Biology |
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The Quarterly Review of Biology |
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70 |
Issue |
2 |
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165-191 |
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Persistence of individual differences in animal behavior in reactions to various environmental challenges could reflect basic divergences in temperament, which might be used to predict details of adaptive response. Although studies have been carried out on fear and anxiety in various species, including laboratory, domestic and wild animals, no consistent definition of fearfulness as a basic trait of temperament has emerged. After a classification of the events that may produce a state of fear, this article describes the great variability in behavior and in physiological patterns generally associated with emotional reactivity. The difficulties of proposing fearfulness-the general capacity to react to a variety of potentially threatening situations-as a valid basic internal variable are then discussed. Although there are many studies showing covariation among the psychobiological responses to different environmental challenges, other studies find no such correlations and raise doubts about the interpretation of fearfulness as a basic personality trait. After a critical assessment of methodologies used in fear and anxiety studies, it is suggested that discrepancies among results are mainly due to the modulation of emotional responses in animals, which depend on numerous genetic and epigenetic factors. It is difficult to compare results obtained by different methods from animals reared under various conditions and with different genetic origins. The concept of fearfulness as an inner trait is best supported by two kinds of investigations. First, an experimental approach combining ethology and experimental psychology produces undeniable indicators of emotional reactivity. Second, genetic lines selected for psychobiological traits prove useful in establishing between behavioral and neuroendocrine aspects of emotional reactivity. It is suggested that fearfulness could be considered a basic feature of the temperament of each individual, one that predisposes it to respond similarly to a variety of potentially alarming challenges, but is nevertheless continually modulated during development by the interaction of genetic traits of reactivity with environmental factors, particularly in the juvenile period. Such interaction may explain much of the interindividual variability observed in adaptive responses. |
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The University of Chicago Press |
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0033-5770 |
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doi: 10.1086/418981 |
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Equine Behaviour @ team @ |
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6664 |
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Hoglund, J.; Alatalo, R.V.; Gibson, R.M.; Lundberg, A. |
Title |
Mate-choice copying in black grouse |
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Journal Article |
Year |
1995 |
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Animal Behaviour. |
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Anim. Behav. |
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49 |
Issue |
6 |
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1627-1633 |
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1817 |
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Custance DM; Whiten A; Bard KA |
Title |
Can young chimpanzees imitate arbitrary actions? Hayes and Hayes (1952) revisited |
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1995 |
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Behavior |
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132 |
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839 |
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Equine Behaviour @ team @ |
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2990 |
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Author |
Gallup GG; Povinelli DJ; Suarez SD; Anderson JR; Lethmate J; Menzel EW |
Title |
Further reflections on self-recognition in primates |
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Journal Article |
Year |
1995 |
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Animal Behaviour. |
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Anim. Behav. |
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50 |
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1525 |
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Equine Behaviour @ team @ |
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2999 |
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Hauser MD; Kralik J; Bott-Mahan C; Garrett M; Oser J |
Title |
Self-recognition in primates: phylogeny and the salience of species-typical traits |
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1995 |
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Proc. Natl. Acad. Sci. USA |
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92 |
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10811 |
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Equine Behaviour @ team @ |
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3003 |
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Author |
Heyes CM |
Title |
Self-recognition in primates: further reflections create a hall of mirrors |
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Journal Article |
Year |
1995 |
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Animal Behaviour. |
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Anim. Behav. |
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50 |
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1533 |
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Equine Behaviour @ team @ |
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3006 |
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Author |
Limongelli L; Boysen ST; Visalberghi E |
Title |
Comprehension of cause-effect relations in a tool-using task by chimpanzees (Pan troglodytes) |
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1995 |
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J. Comp. Psychol. |
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109 |
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18 |
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Equine Behaviour @ team @ |
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3015 |
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Mitchell R |
Title |
Self-recognition, methodology and explanation: a comment on Heyes (1994) |
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1995 |
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Animal Behaviour. |
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Anim. Behav. |
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51 |
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467 |
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Equine Behaviour @ team @ |
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3020 |
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Author |
Pepperberg IM; Garcia SE; Jackson EC; Marconi S |
Title |
Mirror use by African Grey parrots (Psittacus erithacus) |
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1995 |
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J. Comp. Psychol. |
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109 |
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182 |
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Equine Behaviour @ team @ |
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3023 |
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