Records |
Author |
Blokland, A. |
Title |
Reaction time responding in rats |
Type |
Journal Article |
Year |
1998 |
Publication |
Neuroscience and Biobehavioral Reviews |
Abbreviated Journal |
Neurosci Biobehav Rev |
Volume |
22 |
Issue |
6 |
Pages |
847-864 |
Keywords ![sorted by Keywords field, ascending order (up)](img/sort_asc.gif) |
Amphetamine/pharmacology; Animals; Behavior, Animal/drug effects/*physiology; Conditioning, Operant/drug effects/*physiology; Dopamine Uptake Inhibitors/pharmacology; Dose-Response Relationship, Drug; Male; Rats; Rats, Inbred Lew; Reaction Time/drug effects/*physiology |
Abstract |
The use of reaction time has a great tradition in the field of human information processing research. In animal research the use of reaction time test paradigms is mainly limited to two research fields: the role of the striatum in movement initiation; and aging. It was discussed that reaction time responding can be regarded as “single behavior”, this term was used to indicate that only one behavioral category is measured, allowing a better analysis of brain-behavior relationships. Reaction time studies investigating the role of the striatum in motor functions revealed that the initiation of a behavioral response is dependent on the interaction of different neurotransmitters (viz. dopamine, glutamate, GABA). Studies in which lesions were made in different brain structures suggested that motor initiation is dependent on defined brain structures (e.g. medialldorsal striatum, prefrontal cortex). It was concluded that the use of reaction time measures can indeed be a powerful tool in studying brain-behavior relationships. However, there are some methodological constraints with respect to the assessment of reaction time in rats, as was tried to exemplify by the experiments described in the present paper. On the one hand one should try to control for behavioral characteristics of rats that may affect the validity of the parameter reaction time. On the other hand, the mean value of reaction time should be in the range of what has been reported in man. Although these criteria were not always met in several studies, it was concluded that reaction time can be validly assessed in rats. Finally, it was discussed that the use of reaction time may go beyond studies that investigate the role of the basal ganglia in motor output. Since response latency is a direct measure of information processing this parameter may provide insight into basic elements of cognition. Based on the significance of reaction times in human studies the use of this dependent variable in rats may provide a fruitful approach in studying brain-behavior relationships in cognitive functions. |
Address |
Department of Psychology, University of Maastricht, The Netherlands |
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English |
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ISSN |
0149-7634 |
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PMID:9809315 |
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no |
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Equine Behaviour @ team @ |
Serial |
2807 |
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Author |
Kristiansen, K.K.; Kold, S.E. |
Title |
Multivariable analysis of factors influencing outcome of 2 treatment protocols in 128 cases of horses responding positively to intra-articular analgesia of the distal interphalangeal joint |
Type |
Journal Article |
Year |
2007 |
Publication |
Equine Veterinary Journal |
Abbreviated Journal |
Equine Vet J |
Volume |
39 |
Issue |
2 |
Pages |
150-156 |
Keywords ![sorted by Keywords field, ascending order (up)](img/sort_asc.gif) |
Analgesia/methods/*veterinary; Anesthesia, Local/methods/veterinary; Animals; Anti-Inflammatory Agents/therapeutic use; Female; Foot Diseases/drug therapy/prevention & control/*veterinary; Glycosaminoglycans/therapeutic use; Horse Diseases/*drug therapy/prevention & control; Horses; Injections, Intra-Articular/*veterinary; Joint Diseases/drug therapy/prevention & control/veterinary; Lameness, Animal/drug therapy/prevention & control; Male; Methylprednisolone/analogs & derivatives/therapeutic use; Multivariate Analysis; Pain/prevention & control/veterinary; Retrospective Studies; Time Factors; *Toe Joint/drug effects/pathology; Treatment Outcome |
Abstract |
REASONS FOR PERFORMING STUDY: There is limited knowledge available of factors influencing response to treatments of the DIP-joint in horses with lameness responding to diagnostic analgesia of the DIP-joint. For this reason a multivariable statistical analysis was performed. HYPOTHESIS: Horses with lameness reduced by > or = 75% 10 min after intra-articular analgesia of the DIP-joint, can be treated successfully by intra-articular medication of the joint. Multiple factors influence the response to treatment. METHODS: The study was performed retrospectively based on clinical records of horses treated with either polysulphated glycosaminoglycan (PSGAG) or methylprednisolone acetate (MPA) in the DIP-joint between January 1996 and January 2003. Information was collected from clinical records and from the owners of the horses via a detailed questionnaire, in which they described their perception of the outcome a minimum of one year after treatment. Allocation of the horses to the 2 treatment groups was done mainly because of a change in treatment policy. In Regime A all horses received 3 intra-articular injections of PSGAG approximately 8 days apart, whereas in Regime B all horses received a single intra-articular injection of MPA as a first treatment. If the horse did not improve sufficiently to return to work by 4 weeks, a series of 3 intra-articular PSGAG injections was administered. RESULTS: Of the horses receiving Regime A, 67% had a successful outcome, compared with 46% of the group receiving Regime B. A significantly better result was obtained in dressage horses than in jumping horses (eventing and showjumping). Other variables such as age, duration of lameness, distribution of lameness, degree of lameness, response to DIP-joint analgesia and radiographic observations were also associated with success of treatment. CONCLUSIONS AND POTENTIAL RELEVANCE: There is a rationale for using either PSGAG or MPA intra-articularly in the treatment of lameness, reduced > or = 75% within 10 min of analgesia of the DIP-joint. |
Address |
Willesley Equine Clinic Ltd., Tetbury, Gloucestershire, GL8 8QU UK |
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ISSN |
0425-1644 |
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PMID:17378444 |
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no |
Call Number |
Equine Behaviour @ team @ |
Serial |
3707 |
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Author |
Spadavecchia, C.; Arendt-Nielsen, L.; Spadavecchia, L.; Mosing, M.; Auer, U.; van den Hoven, R. |
Title |
Effects of butorphanol on the withdrawal reflex using threshold, suprathreshold and repeated subthreshold electrical stimuli in conscious horses |
Type |
Journal Article |
Year |
2007 |
Publication |
Veterinary anaesthesia and analgesia |
Abbreviated Journal |
Vet Anaesth Analg |
Volume |
34 |
Issue |
1 |
Pages |
48-58 |
Keywords ![sorted by Keywords field, ascending order (up)](img/sort_asc.gif) |
Analgesics, Opioid/pharmacology; Animals; Butorphanol/*pharmacology; Consciousness; Electric Stimulation; Electromyography; Female; Forelimb/physiology; Horses/*physiology; Male; Pain/veterinary; Pain Threshold/*drug effects; Reflex/*drug effects |
Abstract |
OBJECTIVE: To assess the effects of a single intravenous dose of butorphanol (0.1 mg kg(-1)) on the nociceptive withdrawal reflex (NWR) using threshold, suprathreshold and repeated subthreshold electrical stimuli in conscious horses. STUDY DESIGN: 'Unblinded', prospective experimental study. ANIMALS: Ten adult horses, five geldings and five mares, mean body mass 517 kg (range 487-569 kg). METHODS: The NWR was elicited using single transcutaneous electrical stimulation of the palmar digital nerve. Repeated stimulations were applied to evoke temporal summation. Surface electromyography was performed to record and quantify the responses of the common digital extensor muscle to stimulation and behavioural reactions were scored. Before butorphanol administration and at fixed time points up to 2 hours after injection, baseline threshold intensities for NWR and temporal summation were defined and single suprathreshold stimulations applied. Friedman repeated-measures analysis of variance on ranks and Wilcoxon signed-rank test were used with the Student-Newman-Keul's method applied post-hoc. The level of significance (alpha) was set at 0.05. RESULTS: Butorphanol did not modify either the thresholds for NWR and temporal summation or the reaction scores, but the difference between suprathreshold and threshold reflex amplitudes was reduced when single stimulation was applied. Upon repeated stimulation after butorphanol administration, a significant decrease in the relative amplitude was calculated for both the 30-80 and the 80-200 millisecond intervals after each stimulus, and for the whole post-stimulation interval in the right thoracic limb. In the left thoracic limb a decrease in the relative amplitude was found only in the 30-80 millisecond epoch. CONCLUSION: Butorphanol at 0.1 mg kg(-1) has no direct action on spinal Adelta nociceptive activity but may have some supraspinal effects that reduce the gain of the nociceptive system. CLINICAL RELEVANCE: Butorphanol has minimal effect on sharp immediate Adelta-mediated pain but may alter spinal processing and decrease the delayed sensations of pain. |
Address |
Anesthesiology Section, Department of Clinical Veterinary Sciences, Vetsuisse Faculty, University of Berne, Berne, Switzerland. claudia.spadavecchia@veths.no |
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ISSN |
1467-2987 |
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Notes |
PMID:17238962 |
Approved |
no |
Call Number |
refbase @ user @ |
Serial |
92 |
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Author |
Palmer, M.E.; Calve, M.R.; Adamo, S.A. |
Title |
Response of female cuttlefish Sepia officinalis (Cephalopoda) to mirrors and conspecifics: evidence for signaling in female cuttlefish |
Type |
Journal Article |
Year |
2006 |
Publication |
Animal cognition |
Abbreviated Journal |
Anim. Cogn. |
Volume |
9 |
Issue |
2 |
Pages |
151-155 |
Keywords ![sorted by Keywords field, ascending order (up)](img/sort_asc.gif) |
Analysis of Variance; *Animal Communication; Animals; Bias (Epidemiology); Female; Male; Pigmentation/*physiology; Recognition (Psychology)/*physiology; Sepia/*physiology; Visual Perception/*physiology |
Abstract |
Cuttlefish have a large repertoire of body patterns that are used for camouflage and interspecific signaling. Intraspecific signaling by male cuttlefish has been well documented but studies on signaling by females are lacking. We found that females displayed a newly described body pattern termed Splotch toward their mirror image and female conspecifics, but not to males, prey or inanimate objects. Female cuttlefish may use the Splotch body pattern as an intraspecific signal, possibly to reduce agonistic interactions. The ability of females to produce a consistent body pattern in response to conspecifics and mirrors suggests that they can recognize same-sex conspecifics using visual cues, despite the lack of sexual dimorphism visible to human observers. |
Address |
Dorset Environmental Science Centre, Dorset, ON, Canada, P0A 1E0 |
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ISSN |
1435-9448 |
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PMID:16408230 |
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no |
Call Number |
Admin @ knut @ |
Serial |
16 |
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Author |
Lewis, K.P.; Jaffe, S.; Brannon, E.M. |
Title |
Analog number representations in mongoose lemurs (Eulemur mongoz): evidence from a search task |
Type |
Journal Article |
Year |
2005 |
Publication |
Animal Cognition |
Abbreviated Journal |
Anim. Cogn. |
Volume |
8 |
Issue |
4 |
Pages |
247-252 |
Keywords ![sorted by Keywords field, ascending order (up)](img/sort_asc.gif) |
Analysis of Variance; Animals; *Behavior, Animal; *Feeding Behavior; Female; Lemuridae/*psychology; Male; Mathematics; Odors; Smell/physiology; Time Factors |
Abstract |
A wealth of data demonstrating that monkeys and apes represent number have been interpreted as suggesting that sensitivity to number emerged early in primate evolution, if not before. Here we examine the numerical capacities of the mongoose lemur (Eulemur mongoz), a member of the prosimian suborder of primates that split from the common ancestor of monkeys, apes and humans approximately 47-54 million years ago. Subjects observed as an experimenter sequentially placed grapes into an opaque bucket. On half of the trials the experimenter placed a subset of the grapes into a false bottom such that they were inaccessible to the lemur. The critical question was whether lemurs would spend more time searching the bucket when food should have remained in the bucket, compared to when they had retrieved all of the food. We found that the amount of time lemurs spent searching was indicative of whether grapes should have remained in the bucket, and furthermore that lemur search time reliably differentiated numerosities that differed by a 1:2 ratio, but not those that differed by a 2:3 or 3:4 ratio. Finally, two control conditions determined that lemurs represented the number of food items, and neither the odor of the grapes, nor the amount of grape (e.g., area) in the bucket. These results suggest that mongoose lemurs have numerical representations that are modulated by Weber's Law. |
Address |
Department of Anthropology, Washington University, St. Louis, MO 63130-4899, USA |
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1435-9448 |
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PMID:15660208 |
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no |
Call Number |
Equine Behaviour @ team @ |
Serial |
2497 |
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Author |
Soproni, K.; Miklósi, Á.; Topál, J.; Csányi, V. |
Title |
Dogs' (Canis familiaris) responsiveness to human pointing gestures |
Type |
Journal Article |
Year |
2002 |
Publication |
Journal of Comparative Psychology (Washington, D.C. : 1983) |
Abbreviated Journal |
J Comp Psychol |
Volume |
116 |
Issue |
1 |
Pages |
27-34 |
Keywords ![sorted by Keywords field, ascending order (up)](img/sort_asc.gif) |
Analysis of Variance; Animals; *Behavior, Animal; Choice Behavior; Dogs/*psychology; Female; Gestures; Male; *Recognition (Psychology); Species Specificity |
Abstract |
In a series of 3 experiments, dogs (Canis familiaris) were presented with variations of the human pointing gesture: gestures with reversed direction of movement, cross-pointing, and different arm extensions. Dogs performed at above chance level if they could see the hand (and index finger) protruding from the human body contour. If these minimum requirements were not accessible, dogs still could rely on the body position of the signaler. The direction of movement of the pointing arm did not influence the performance. In summary, these observations suggest that dogs are able to rely on relatively novel gestural forms of the human communicative pointing gesture and that they are able to comprehend to some extent the referential nature of human pointing. |
Address |
Department of Ethology, Eotvos Lorand University, Budapest, Hungary. krisztinasoproni@hotmail.com |
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0735-7036 |
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PMID:11926681 |
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no |
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Equine Behaviour @ team @ |
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4962 |
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Author |
Weaver, A.; de Waal, F.B.M. |
Title |
An index of relationship quality based on attachment theory |
Type |
Journal Article |
Year |
2002 |
Publication |
Journal of comparative psychology (Washington, D.C. : 1983) |
Abbreviated Journal |
J Comp Psychol |
Volume |
116 |
Issue |
1 |
Pages |
93-106 |
Keywords ![sorted by Keywords field, ascending order (up)](img/sort_asc.gif) |
Analysis of Variance; Animals; *Behavior, Animal; Female; Male; *Maternal Behavior; *Object Attachment; Pan troglodytes/*psychology; Pilot Projects |
Abstract |
Two measures are reported of the nature or quality of a mother-offspring (MO) relationship during development using brown capuchin monkeys (Cebus apella) as models. One is a qualitative classification of MO relationships as secure, resistant, or avoidant attachments. The other is an empirical ratio of relative affiliation to agonism called the MO relationship quality, or MORQ, Index. The two methods tapped similar relationship features so relationships high or low of a median split of MORQ values were heuristically labeled secure (n = 22) or insecure (n = 16), respectively. A comparison revealed extensive behavioral differences between secure and insecure MO relationships and suggested MORQ provided an objective, continuous measure of attachment security. |
Address |
Yerkes Regional Primate Research Center, Emory University, USA. achweaver@att.net |
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0735-7036 |
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PMID:11930937 |
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no |
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refbase @ user @ |
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183 |
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Author |
McGreevy, P.D.; Nicol, C.J. |
Title |
The effect of short-term prevention on the subsequent rate of crib-biting in thoroughbred horses |
Type |
Journal Article |
Year |
1998 |
Publication |
Equine veterinary journal. Supplement |
Abbreviated Journal |
Equine Vet J Suppl |
Volume |
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Issue |
27 |
Pages |
30-34 |
Keywords ![sorted by Keywords field, ascending order (up)](img/sort_asc.gif) |
Analysis of Variance; Animals; *Behavior, Animal; Horse Diseases/*prevention & control/psychology; Horses; Male; Recurrence; *Stereotyped Behavior; Videotape Recording |
Abstract |
The results of an experimental study of the motivational consequences of short-term prevention of crib-biting are reported here. Eight test horses wore a cribbing collar for 24 h. This was effective in preventing crib-biting in 6 subjects. Using analysis of co-variance that accounted for baseline differences in crib-biting rate, test horses showed significantly more crib-biting than control horses on the first day after prevention (P < 0.05). There was also a highly significant increase in the crib-biting rate of test horses on the first day after prevention in comparison with their baseline rate (P < 0.01). This defines the increase as a post inhibitory rebound. An increase in the novelty of the cribbing bar and an increase in feeding motivation during the period of prevention are rejected as explanations of the rebound in this study. Instead, it is suggested that the rebound reflected a rise in internal motivation to crib-bite during the period of prevention. Behaviours that exhibit this pattern of motivation are generally considered functional; and it has been argued that their prevention may compromise welfare. |
Address |
Department of Clinical Veterinary Science, University of Bristol, UK |
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PMID:10485001 |
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no |
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refbase @ user @ |
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88 |
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Author |
Murai, C.; Tomonaga, M.; Kamegai, K.; Terazawa, N.; Yamaguchi, M.K. |
Title |
Do infant Japanese macaques ( Macaca fuscata) categorize objects without specific training? |
Type |
Journal Article |
Year |
2004 |
Publication |
Primates |
Abbreviated Journal |
Primates |
Volume |
45 |
Issue |
1 |
Pages |
1-6 |
Keywords ![sorted by Keywords field, ascending order (up)](img/sort_asc.gif) |
Analysis of Variance; Animals; *Cognition; *Concept Formation; *Generalization, Stimulus; Japan; Macaca/*psychology; Male |
Abstract |
In the present study, we examined whether infant Japanese macaques categorize objects without any training, using a similar technique also used with human infants (the paired-preference method). During the familiarization phase, subjects were presented twice with two pairs of different objects from one global-level category. During the test phase, they were presented twice with a pair consisting of a novel familiar-category object and a novel global-level category object. The subjects were tested with three global-level categories (animal, furniture, and vehicle). It was found that they showed significant novelty preferences as a whole, indicating that they processed similarities between familiarization objects and novel familiar-category objects. These results suggest that subjects responded distinctively to objects without training, indicating the possibility that infant macaques possess the capacity for categorization. |
Address |
Department of Psychology, Graduate School of Letters, Kyoto University, Sakyo, Kyoto 606-8501, Japan. cmurai@bun.kyoto-u.ac.jp |
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0032-8332 |
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PMID:14505179 |
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Equine Behaviour @ team @ |
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2813 |
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Author |
Maninger, N.; Capitanio, J.P.; Mendoza, S.P.; Mason, W.A. |
Title |
Personality influences tetanus-specific antibody response in adult male rhesus macaques after removal from natal group and housing relocation |
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Journal Article |
Year |
2003 |
Publication |
American journal of primatology |
Abbreviated Journal |
Am. J. Primatol. |
Volume |
61 |
Issue |
2 |
Pages |
73-83 |
Keywords ![sorted by Keywords field, ascending order (up)](img/sort_asc.gif) |
Analysis of Variance; Animals; Antibody Formation; Enzyme-Linked Immunosorbent Assay; Housing, Animal; Immunization, Secondary/*veterinary; Immunoglobulin G/blood; Macaca mulatta/*immunology/physiology; Male; *Personality; Social Behavior; Tetanus Toxoid/*immunology |
Abstract |
Previous research has suggested that personality is related to immune function in macaques. Using a prospective design, we examined whether variation in the personality dimension “Sociability” in adult male rhesus macaques (Macaca mulatta) was related to the in vivo secondary antibody response to a tetanus toxoid booster immunization following removal from natal groups and relocation to individual housing. We also explored whether the timing of the immunization following relocation had an impact on the immune response. Blood was sampled at the time of booster immunization, at 14 and 28 days post-immunization, and approximately 9 months post-immunization. Plasma was assayed for tetanus-specific IgG by enzyme-linked immunoassay (ELISA). There was no difference between High- and Low-Sociable animals in antibody levels at the time of the booster immunization. Multivariate analysis of variance (MANOVA) revealed that High-Sociable animals had a significantly higher antibody response following relocation and immunization compared to Low-Sociable animals. There was no effect of timing of the immunization on the immune response. The results confirm that personality factors can affect animals' immune responses, and that the dimension Sociability may be influential in a male's response to social separation and relocation. |
Address |
Department of Psychology, and Mind and Behavior Unit, California National Primate Research Center, University of California-Davis, Davis, California 95616, USA. nmaniger@ucdavis.edu |
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0275-2565 |
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PMID:14582129 |
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Equine Behaviour @ team @ |
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4114 |
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