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Author Petter-Puchner, A.H.; Froetscher, W.; Krametter-Froetscher, R.; Lorinson, D.; Redl, H.; van Griensven, M.
Title The long-term neurocompatibility of human fibrin sealant and equine collagen as biomatrices in experimental spinal cord injury Type Journal Article
Year 2007 Publication Experimental and Toxicologic Pathology : Official Journal of the Gesellschaft fur Toxikologische Pathologie Abbreviated Journal Exp Toxicol Pathol
Volume 58 Issue 4 Pages 237-245
Keywords (up) Animals; Axotomy; Biocompatible Materials/*therapeutic use; Collagen/*therapeutic use; Fibrin Tissue Adhesive/*therapeutic use; Horses; Humans; Immunohistochemistry; Male; Motor Activity/physiology; Nerve Regeneration/*physiology; Rats; Recovery of Function; Spinal Cord/pathology/physiology; Spinal Cord Injuries/pathology/*therapy; Thoracic Vertebrae
Abstract INTRODUCTION: While fibrin sealant (FS) and equine collagen (EC) have been used as scaffold materials in experimental spinal cord injury (SCI), questions concerning neurocompatibility still remain. In this study, we assessed potential adverse effects, as well as functional and histological impact of FS and EC in subtotal hemisection of the thoracic spinal cord (SC) in rats. METHODS: 124 male rats were randomly assigned to four main groups (n=31): Sham (SH), Lesion only (L), fibrin sealant (GFS) and equine collagen group (GEC). SH animals received laminectomy only; all other animals underwent subtotal lateral hemisection at T9. Treatment consisted of application of FS or EC into the lesion gap in GFS and GEC, which was left empty in L. GFS, GEC, L and SH were each further divided into 4 subgroups: One subgroup, consisting of 10 rats was subjected to behavioural and reflex testing before surgery and followed up on days 1,7, 14, 21, 28 post op and then sacrificed. Haemalaun or cresyl violet (CV) was used to identify neutrophils in parasagittal cord sections which were obtained on day 1 (n=7). Sections stained for quantification of microglia/macrophages using ED-1 on day 3 (n=7), day 7 (n=7) and day 28 (n=7 out of 10). Additionally, neural filament (NF) staining was chosen to detect axonal regeneration and the length of ingrowth into FS and EC, Luxol blue for myelination, Von Willebrand factor for vascularisation, and glial fibrillary acidic protein (GFAP) staining for detection of astrocytes in glial scars on day 28. RESULTS: No adverse effects were observed in the treatment groups. Compared to L, GFS and GEC performed significantly better in the Basso, Beattie, Bresnahan (BBB) score and hopping responses. Proprioceptive placing was markedly improved in FS and EC compared to L. Axonal regrowth was found in GFS and GEC--the regrowth in the GFS was accompanied by myelination and vascularisation. Glial scarring occurred in all groups. Discussion Both biomatrices improved functional recovery compared to L and no adverse effects were perceived.
Address Ludwig Boltzmann Institute of Experimental and Clinical Traumatology, Donaueschingenstrasse 13, 1200-Vienna, Austria
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Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0940-2993 ISBN Medium
Area Expedition Conference
Notes PMID:17118635 Approved no
Call Number Serial 1852
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Author Piccione, G.; Caola, G.; Refinetti, R.
Title Temporal relationships of 21 physiological variables in horse and sheep Type Journal Article
Year 2005 Publication Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology Abbreviated Journal Comp Biochem Physiol A Mol Integr Physiol
Volume 142 Issue 4 Pages 389-396
Keywords (up) Animals; Behavior, Animal/physiology; Blood Glucose/physiology; Body Temperature/*physiology; Circadian Rhythm/*physiology; Female; Horses/*physiology; Melatonin/blood/*physiology; Motor Activity/*physiology; Rectum/physiology; Sheep/*physiology; Time Factors
Abstract Daily or circadian oscillation has been documented in a variety of physiological and behavioral processes. Although individual variables have been studied in great detail, very few studies have been conducted on the temporal relationships between the rhythms of different variables. It is not known whether the circadian pacemaker generates each and every rhythm individually or whether most rhythms are simply derived from a few clock-controlled rhythms. As a first step in elucidating this issue, 21 physiological variables were recorded simultaneously in horse and sheep. The results indicated that, in both species, different variables exhibit different degrees of daily rhythmicity and reach their daily peaks at different times of the day. The variables exhibiting strongest rhythmicity were locomotor activity, rectal temperature, and plasma concentrations of melatonin and glucose. Comparison of rhythmicity and acrophase in the various rhythms allowed inferences to be made about mechanisms of causation.
Address Dipartimento di Morfologia, Biochimica, Fisiologia e Produzioni Animali, Facolta di Medicina Veterinaria, Universita degli Studi di Messina, 98168 Messina, Italy
Corporate Author Thesis
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Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1095-6433 ISBN Medium
Area Expedition Conference
Notes PMID:16290083 Approved no
Call Number Serial 1884
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Author McCutcheon, L.J.; Geor, R.J.
Title Influence of training on sweating responses during submaximal exercise in horses Type Journal Article
Year 2000 Publication Journal of Applied Physiology (Bethesda, Md. : 1985) Abbreviated Journal J Appl Physiol
Volume 89 Issue 6 Pages 2463-2471
Keywords (up) Animals; Body Fluids/metabolism; Body Temperature; Body Weight; Environment; Female; Horses/*physiology; Ions; Male; Motor Activity/*physiology; Oxygen Consumption; Physical Conditioning, Animal/*physiology; Sweat/chemistry; Sweating/*physiology; Time Factors
Abstract Sweating responses were examined in five horses during a standardized exercise test (SET) in hot conditions (32-34 degrees C, 45-55% relative humidity) during 8 wk of exercise training (5 days/wk) in moderate conditions (19-21 degrees C, 45-55% relative humidity). SETs consisting of 7 km at 50% maximal O(2) consumption, determined 1 wk before training day (TD) 0, were completed on a treadmill set at a 6 degrees incline on TD0, 14, 28, 42, and 56. Mean maximal O(2) consumption, measured 2 days before each SET, increased 19% [TD0 to 42: 135 +/- 5 (SE) to 161 +/- 4 ml. kg(-1). min(-1)]. Peak sweating rate (SR) during exercise increased on TD14, 28, 42, and 56 compared with TD0, whereas SRs and sweat losses in recovery decreased by TD28. By TD56, end-exercise rectal and pulmonary artery temperature decreased by 0.9 +/- 0.1 and 1.2 +/- 0.1 degrees C, respectively, and mean change in body mass during the SET decreased by 23% (TD0: 10.1 +/- 0.9; TD56: 7.7 +/- 0.3 kg). Sweat Na(+) concentration during exercise decreased, whereas sweat K(+) concentration increased, and values for Cl(-) concentration in sweat were unchanged. Moderate-intensity training in cool conditions resulted in a 1.6-fold increase in sweating sensitivity evident by 4 wk and a 0.7 +/- 0.1 degrees C decrease in sweating threshold after 8 wk during exercise in hot, dry conditions. Altered sweating responses contributed to improved heat dissipation during exercise and a lower end-exercise core temperature. Despite higher SRs for a given core temperature during exercise, decreases in recovery SRs result in an overall reduction in sweat fluid losses but no change in total sweat ion losses after training.
Address Department of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada N1G 2W1. jmccutch@uoguelph.ca
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ISSN 8750-7587 ISBN Medium
Area Expedition Conference
Notes PMID:11090603 Approved no
Call Number refbase @ user @ Serial 1922
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Author Rizzolatti, G.; Fogassi, L.; Gallese, V.
Title Mirrors of the mind Type Journal Article
Year 2006 Publication Scientific American Abbreviated Journal Sci Am
Volume 295 Issue 5 Pages 54-61
Keywords (up) Animals; Brain/*physiology; Cognition/*physiology; Discrimination (Psychology)/physiology; Emotions/physiology; Humans; Imitative Behavior; Learning/*physiology; Mental Processes/*physiology; Motor Activity/physiology; Neurons/physiology; Recognition (Psychology); Sensation/physiology
Abstract
Address Neurosciences Department, University of Parma, Italy
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ISSN 0036-8733 ISBN Medium
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Notes PMID:17076084 Approved no
Call Number Equine Behaviour @ team @ Serial 2829
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Author Gill, J.
Title A new method for continuous recording of motor activity in horses Type Journal Article
Year 1991 Publication Comparative Biochemistry and Physiology. A, Comparative Physiology Abbreviated Journal Comp Biochem Physiol A
Volume 99 Issue 3 Pages 333-341
Keywords (up) Animals; Circadian Rhythm; Female; Horses/*physiology; Monitoring, Physiologic/instrumentation/*veterinary; *Motor Activity; Signal Processing, Computer-Assisted
Abstract 1. The use of an electronic recorder for the horse motor activity was described. 2. Examples of different types of motor activities are given in Figs 1-8. 3. The ultradian pattern of activity in all records was stressed. 4. The possibility of receiving of more physiological informations by this type of apparatus is discussed.
Address Department of Vertebrate Animal Physiology, University of Warsaw, Poland
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ISSN 0300-9629 ISBN Medium
Area Expedition Conference
Notes PMID:1678331 Approved no
Call Number refbase @ user @ Serial 1950
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Author Ratzlaff, M.H.; Wilson, P.D.; Hyde, M.L.; Balch, O.K.; Grant, B.D.
Title Relationship between locomotor forces, hoof position and joint motion during the support phase of the stride of galloping horses Type Journal Article
Year 1993 Publication Acta Anatomica Abbreviated Journal Acta Anat (Basel)
Volume 146 Issue 2-3 Pages 200-204
Keywords (up) Animals; Equipment Design; Hoof and Claw/*physiology; Horses/*physiology; Joints/*physiology; *Locomotion; Motor Activity/*physiology; Physiology/instrumentation; *Posture; Shoes; Transducers
Abstract Three methods were used simultaneously to determine the relationships between the vertical forces exerted on the hooves and the positions of the limbs and hooves at the times of peak vertical forces from 2 horses galloping on a track straightaway. Vertical forces were recorded from an instrumented shoe, fetlock joint motion was measured with an electrogoniometer and the angles of the carpus, fetlock and hoof were determined from slow-motion films. At hoof contact, the mean angles of the carpus and fetlock were 181-182 degrees and 199-206 degrees, respectively. Peak vertical forces on the heel occurred at or near maximum extension of the carpal and fetlock joints. Peak forces on the toe occurred during flexion of the fetlock joint and at mean hoof angles of 28-31 degrees from the horizontal. The mean angles of the hoof from the horizontal at the time of heel contact were 6-7 degrees. Hoof lift occurred at mean carpal angles of 173-174 degrees and mean fetlock angles of 199-200 degrees.
Address Department of Veterinary and Comparative Anatomy, Pharmacology and Physiology, College of Veterinary Medicine, Washington State University, Pullman 99164-6520
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Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0001-5180 ISBN Medium
Area Expedition Conference
Notes PMID:8470468 Approved no
Call Number refbase @ user @ Serial 1945
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Author Davies, H.M.S.
Title The timing and distribution of strains around the surface of the midshaft of the third metacarpal bone during treadmill exercise in one Thoroughbred racehorse Type Journal Article
Year 2005 Publication Australian Veterinary Journal Abbreviated Journal Aust Vet J
Volume 83 Issue 3 Pages 157-162
Keywords (up) Animals; Exercise Test/veterinary; Female; Gait/*physiology; Horses/*physiology; Metacarpus/*physiology; Motor Activity/physiology; Physical Conditioning, Animal/*physiology; Stress, Mechanical; Weight-Bearing/physiology
Abstract OBJECTIVE: To confirm that the midshaft dorsal cortex of the third metacarpal bone experienced higher compressive strains during fast exercise than the medial or lateral cortices, and that the strain peak occurred earlier in the hoof-down phase of the stride on the dorsal cortex than the medial or lateral cortices. DESIGN: Observations of a single horse. PROCEDURE: Strains were collected from a single, sound, 3-year-old Thoroughbred mare during treadmill exercise from rosette strain gauges implanted onto the medial, lateral and dorsal surfaces of the midshaft of the right cannon bone, simultaneously with data from a hoof switch that showed when the hoof was in the stance phase. RESULTS: Peak compressive strains on the dorsal surface of the third metacarpal bone were proportional to exercise speed and occurred at about 30% of stance. Peak compressive strains on the medial surface of the non-lead limb reached a maximum at a speed around 10 m/s and occurred at mid-stance. Peak compressive strains on the lateral surface varied in timing and size between strides at all exercise speeds, but remained less than -2000 microstrains. CONCLUSIONS: The timing of peak compressive strains on the dorsal cortex suggests a relationship to deceleration of the limb following hoof impact, so the main determinants of their size would be exercise speed and turning (as shown in previous experiments). This experiment confirms data from other laboratories that were published but not discussed, that peak compressive strains on the medial surface occur at mid-stance. This suggests that they are related to the support of body weight. The strains on the lateral cortex occurred at variable times so may be associated with the maintenance of balance as well as the support of body weight. Understanding the loading of the third metacarpal bone will help to determine causes of damage to it and ways in which the bone might be conditioned to prevent such damage.
Address Department of Veterinary Science, University of Melbourne, Parkville, Victoria 3010. h.davies@unimelb.edu.au
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Series Volume Series Issue Edition
ISSN 0005-0423 ISBN Medium
Area Expedition Conference
Notes PMID:15825628 Approved no
Call Number Serial 1891
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Author Zentall, S.S.; Zentall, T.R.
Title Hyperactivity ratings: statistical regression provides an insufficient explanation of practice effects Type Journal Article
Year 1986 Publication Journal of pediatric psychology Abbreviated Journal J Pediatr Psychol
Volume 11 Issue 3 Pages 393-396
Keywords (up) Attention Deficit Disorder with Hyperactivity/*diagnosis; Child; Humans; Male; *Practice (Psychology); *Statistics
Abstract
Address
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ISSN 0146-8693 ISBN Medium
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Notes PMID:3772683 Approved no
Call Number refbase @ user @ Serial 261
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Author Sarova, R.; Spinka, M.; Panama, J.L.A.
Title Synchronization and leadership in switches between resting and activity in a beef cattle herd--A case study Type Journal Article
Year 2007 Publication Applied Animal Behaviour Science Abbreviated Journal Appl. Anim. Behav. Sci.
Volume 108 Issue 3-4 Pages 327-331
Keywords (up) Beef cattle; Activity synchronization; Leadership; Dominance
Abstract The mechanisms of activity synchronization in group living ungulates are not well understood. In a case study on herd of 15 Gasconne beef cows with calves observed during a total of 25 summer daylight periods in 2004 and 2005, we examined whether cows similar to each other in body weight or in reproductive status were more synchronized and whether the timing of activity switches were determined by specific leading animals. We calculated the synchronization of all possible pairs of cows in the herd and tested the effects of similarity in body weight and in reproductive status (lactating versus non-lactating) on synchronization in the pair. Further, we assessed whether any specific individuals, and especially the dominant cows, were more able, through their own activity switch, to incite another cow to follow shortly with her switch in activity. We found that body weight differences had a negative influence on pair synchronization (GLMM, F1,65 = 6.79; p < 0.05), but reproductive status did not affect the synchronization. Cows' individual identity explained only a small proportion (<2%) of variability in intervals between switches of subsequent cows. Furthermore, dominance status of an individual cow did not correlate with mean interval between her activity switches and activity switches of the next cow (lying down: Spearman correlation, rs = -0.16, n = 14, p > 0.10; standing up: Spearman correlation, rs = -0.38, n = 14, p > 0.10), indicating that there were no leading animals initiating switches in activity in our herd.
Address
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Notes Approved no
Call Number Serial 2025
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Author Slingerland, L.I.; Robben, J.H.; Schaafsma, I.; Kooistra, H.S.
Title Response of cats to familiar and unfamiliar human contact using continuous direct arterial blood pressure measurement Type Journal Article
Year 2008 Publication Research in Veterinary Science Abbreviated Journal
Volume 85 Issue 3 Pages 575-582
Keywords (up) Behaviour; Activity; Technique; White-coat effect; Diurnal rhythm; Invasive
Abstract Continuous direct measurement of feline arterial blood pressure (ABP) was carried out via a modified method with percutaneous, ultrasound guided catheterization of the common carotid artery. In 21 healthy, conscious cats the ABP was measured during rest, alertness and activity. Furthermore, the ABP response to being petted by familiar and unfamiliar persons was assessed. Linear mixed modelling revealed that the mean blood pressure (MBP) in resting cats (114.6 mmHg) was lower (P < 0.001) than in alert cats (122.7 mmHg), which was lower (P < 0.001) than that of active cats (136.8 mmHg). The MBP during petting by a familiar person (144.7 mmHg) tended to be higher (P = 0.065) than that during petting by an unfamiliar person (139.4 mmHg). The MBP of active cats was lower (P = 0.003) than MBP of cats petted by a familiar person, but not different from MBP of cats petted by an unfamiliar person. The MBP returned to resting values between 16 and 20 min after the familiar person had left, whereas resting values were reached between 11 and 15 min after the unfamiliar person had left. The complications of the described method were limited considering the potential risks of continuous direct ABP measurement. In conclusion, the described technique enables accurate measurement of feline ABP, which is influenced by the cat's activity level and the familiarity of persons.
Address
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ISSN 0034-5288 ISBN Medium
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Notes Approved no
Call Number Equine Behaviour @ team @ Serial 4982
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