| Records |
| Author |
Wells, P.G.; Bhuller, Y.; Chen, C.S.; Jeng, W.; Kasapinovic, S.; Kennedy, J.C.; Kim, P.M.; Laposa, R.R.; McCallum, G.P.; Nicol, C.J.; Parman, T.; Wiley, M.J.; Wong, A.W. |
| Title |
Molecular and biochemical mechanisms in teratogenesis involving reactive oxygen species |
Type |
Journal Article |
| Year |
2005 |
Publication |
Toxicology and applied pharmacology |
Abbreviated Journal |
Toxicol Appl Pharmacol |
| Volume |
207 |
Issue |
2 Suppl |
Pages |
354-366 |
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| Abstract |
Developmental pathologies may result from endogenous or xenobiotic-enhanced formation of reactive oxygen species (ROS), which oxidatively damage cellular macromolecules and/or alter signal transduction. This minireview focuses upon several model drugs (phenytoin, thalidomide, methamphetamine), environmental chemicals (benzo[a]pyrene) and gamma irradiation to examine this hypothesis in vivo and in embryo culture using mouse, rat and rabbit models. Embryonic prostaglandin H synthases (PHSs) and lipoxygenases bioactivate xenobiotics to free radical intermediates that initiate ROS formation, resulting in oxidation of proteins, lipids and DNA. Oxidative DNA damage and embryopathies are reduced in PHS knockout mice, and in mice treated with PHS inhibitors, antioxidative enzymes, antioxidants and free radical trapping agents. Thalidomide causes embryonic DNA oxidation in susceptible (rabbit) but not resistant (mouse) species. Embryopathies are increased in mutant mice deficient in the antioxidative enzyme glucose-6-phosphate dehydrogenase (G6PD), or by glutathione (GSH) depletion, or inhibition of GSH peroxidase or GSH reductase. Inducible nitric oxide synthase knockout mice are partially protected. Inhibition of Ras or NF-kB pathways reduces embryopathies, implicating ROS-mediated signal transduction. Atm and p53 knockout mice deficient in DNA damage response/repair are more susceptible to xenobiotic or radiation embryopathies, suggesting a teratological role for DNA damage, consistent with enhanced susceptibility to methamphetamine in ogg1 knockout mice with deficient repair of oxidative DNA damage. Even endogenous embryonic oxidative stress carries a risk, since untreated G6PD- or ATM-deficient mice have increased embryopathies. Thus, embryonic processes regulating the balance of ROS formation, oxidative DNA damage and repair, and ROS-mediated signal transduction may be important determinants of teratological risk. |
| Address |
Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada; Department of Pharmacology, University of Toronto, Toronto, Ontario, Canada |
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English |
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Edition |
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| ISSN |
0041-008X |
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| Notes |
PMID:16081118 |
Approved |
no |
| Call Number |
refbase @ user @ |
Serial |
68 |
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| Author |
Salter Re, P.D. |
| Title |
Determinants of mineral lick utilization by feral horses |
Type |
Journal Article |
| Year |
1980 |
Publication |
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Abbreviated Journal |
Northwest Sci |
| Volume |
54 |
Issue |
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Pages |
109-118 |
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| Notes |
from Professor Hans Klingels Equine Reference List |
Approved |
no |
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Serial |
1554 |
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| Author |
Young E, P.B. |
| Title |
The reaction of the Cape Mountain Zebra(E. Zebra Zebra) to certain chemical immobilisation drugs |
Type |
Journal Article |
| Year |
1972 |
Publication |
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Abbreviated Journal |
Koedoe |
| Volume |
15 |
Issue |
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Pages |
95-96 |
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| Notes |
from Professor Hans Klingels Equine Reference List |
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no |
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Serial |
1727 |
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| Author |
Balenghien, T.; Fouque, F.; Sabatier, P.; Bicout, D.J. |
| Title |
Horse-, bird-, and human-seeking behavior and seasonal abundance of mosquitoes in a West Nile virus focus of southern France |
Type |
Journal Article |
| Year |
2006 |
Publication |
Journal of Medical Entomology |
Abbreviated Journal |
J Med Entomol |
| Volume |
43 |
Issue |
5 |
Pages |
936-946 |
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| Abstract |
After 35 yr of disease absence, West Nile virus (family Flaviviridae, genus Flavivirus, WNV) circulation has been regularly detected in the Camargue region (southern France) since 2000. WNV was isolated from Culex modestus Ficalbi, which was considered the main vector in southern France after horse outbreaks in the 1960s. Recent WNV transmissions outside of the Cx. modestus distribution suggested the existence of other vectors. To study potential WNV vectors, horse- and bird-baited traps and human landing collections of mosquitoes were carried out weekly from May to October 2004 at two Camargue sites: one site in a wet area and the other site in a dry area, both chosen for their past history of WNV transmission. At the wet site, the most abundant species in bird-baited traps were Culex pipiens L. and Cx. modestus; both species also were found in lower proportions on horses and humans. The most abundant species in horse-baited traps and human landing collections were Aedes caspius (Pallas), Aedes vexans (Meigen), and Anopheles hyrcanus (Pallas) sensu lato; some of these species were occasionally collected with avian blood at the end of the summer. Anopheles maculipennis Meigen sensu lato was an abundant horse feeder, but it was rarely collected landing on human bait and never contained avian blood. At the dry site, Cx. pipiens was the most abundant species in bird- and horse-baited traps. The seasonal and circadian dynamics of these species are analyzed, and their potential in WNV transmission in Camargue discussed. |
| Address |
Unite Biomathematiques et epidemiologie, Ecole Nationale Veterinaire de Lyon, 1 avenue Bourgelat, 69280 Marcy l'Etoile, France |
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English |
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0022-2585 |
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| Notes |
PMID:17017231 |
Approved |
no |
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Serial |
1859 |
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| Author |
McGreevy, P. |
| Title |
Equine behavior |
Type |
Journal Article |
| Year |
2004 |
Publication |
Journal of Equine Veterinary Science |
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| Volume |
24 |
Issue |
9 |
Pages |
397-398 |
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no |
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refbase @ user @ |
Serial |
1983 |
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| Author |
Hvorecny, L.M.; Grudowski, J.L.; Blakeslee, C.J.; Simmons, T.L.; Roy, P.R.; Brooks, J.A.; Hanner, R.M.; Beigel, M.E.; Karson, M.A.; Nichols, R.H.; Holm, J.B.; Boal, J.G. |
| Title |
Octopuses (Octopus bimaculoides) and cuttlefishes (Sepia pharaonis, S. officinalis) can conditionally discriminate |
Type |
Journal Article |
| Year |
2007 |
Publication |
Animal Cognition |
Abbreviated Journal |
Anim. Cogn. |
| Volume |
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Issue |
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Pages |
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| Abstract |
In complex navigation using landmarks, an animal must discriminate between potential cues and show context (condition) sensitivity. Such conditional discrimination is considered a form of complex learning and has been associated primarily with vertebrates. We tested the hypothesis that octopuses and cuttlefish are capable of conditional discrimination. Subjects were trained in two maze configurations (the conditions) in which they were required to select one of two particular escape routes within each maze (the discrimination). Conditional discrimination could be demonstrated by selecting the correct escape route in each maze. Six of ten mud-flat octopuses (Octopus bimaculoides), 6 of 13 pharaoh cuttlefish (Sepia pharaonis), and one of four common cuttlefish (S. officinalis) demonstrated conditional discrimination by successfully solving both mazes. These experiments demonstrate that cephalopods are capable of conditional discrimination and extend the limits of invertebrate complex learning. |
| Address |
Department of Biology, Millersville University, 50 East Frederick Street, Millersville, PA, 17551-0302, USA, jean.boal@millersville.edu |
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English |
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1435-9448 |
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| Notes |
PMID:17437139 |
Approved |
no |
| Call Number |
Equine Behaviour @ team @ |
Serial |
2405 |
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| Author |
Clauss, M.; Castell, J.C.; Kienzle, E.; Schramel, P.; Dierenfeld, E.S.; Flach, E.J.; Behlert, O.; Streich, W.J.; Hummel, J.; Hatt, J.-M. |
| Title |
Mineral absorption in the black rhinoceros (Diceros bicornis) as compared with the domestic horse |
Type |
Journal Article |
| Year |
2007 |
Publication |
Journal of Animal Physiology and Animal Nutrition |
Abbreviated Journal |
J Anim Physiol Anim Nutr (Berl) |
| Volume |
91 |
Issue |
5-6 |
Pages |
193-204 |
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| Abstract |
To test whether mineral recommendations for horses are likely to guarantee adequate mineral provision for black rhinoceroses (Diceros bicornis), we investigated the apparent absorption (aA) of macro- and microminerals in eight black rhinoceroses from three zoological institutions in a total of 32 feeding trials with total faecal collection, with additional data from three unpublished studies (18 feeding trials). Feeds and faeces were analysed for Ca, P, Mg, Na, K, Fe, Mn, Cu, Zn and Co. The resulting aA coefficients, and the linear relationships of apparently absorbable dietary mineral content to total dietary mineral content [per 100 g dry matter (DM)], were compared with data for domestic horses. Rhinoceroses had significantly higher aA coefficients for Ca and Mg (because of a higher calculated 'true' absorption), and lower ones for Na and K (because of calculated higher endogenous faecal losses). High absorption efficiency for divalent cations is hypothesized to be an adaptation to a natural diet of particularly high Ca:P ratio (approximately 14:1); an effective removal of Ca from the ingesta guarantees sufficient P availability at the fermentation site in the hindgut. Higher faecal losses of Na and K are hypothesized to be linked to a higher faecal bulk per DM intake in black rhinoceroses as compared with horses because of a generally lower digestive efficiency. There were no relevant differences in the absorption patterns of microminerals. In particular, there were no discernable differences in Fe absorption within the rhinoceroses for diets with and without tannin supplementation. Several of the zoo diets assessed in this study were deficient in Cu, Mn or Zn, and most contained excessive levels of Fe when compared with horse requirements. The findings of this study indicate that differences in mineral absorption between occur even between species of similar digestive anatomy; that in particular, Ca absorption might vary between hindgut fermenters with Ca:P ratio in their natural diet; that Na might be a particularly limiting factor in the ecology of free-ranging rhinoceroses; that moderate doses of tannins do not seem to markedly influence mineral absorption; and that diets for captive animals should contain adequate, but not excessive mineral levels. |
| Address |
Division of Zoo Animals, Exotic Pets and Wildlife, Vetsuisse Faculty, University of Zurich, Switzerland. mclauss@vetclinics.uzh.ch |
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0931-2439 |
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| Notes |
PMID:17516940 |
Approved |
no |
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Equine Behaviour @ team @ |
Serial |
2619 |
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| Author |
Davis, S.L.; Cheeke, P.R. |
| Title |
Do domestic animals have minds and the ability to think? A provisional sample of opinions on the question |
Type |
Journal Article |
| Year |
1998 |
Publication |
Journal of Animal Science |
Abbreviated Journal |
J. Anim Sci. |
| Volume |
76 |
Issue |
8 |
Pages |
2072-2079 |
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no |
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Equine Behaviour @ team @ |
Serial |
2930 |
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| Author |
Ottoni, E.; de Resende, B.; Izar, P. |
| Title |
Erratum |
Type |
Journal Article |
| Year |
2006 |
Publication |
Animal Cognition |
Abbreviated Journal |
Anim. Cogn. |
| Volume |
9 |
Issue |
2 |
Pages |
156-156 |
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Without Abstract |
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no |
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Equine Behaviour @ team @ |
Serial |
3258 |
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| Author |
Hauber, M.E.; Sherman, P.W.; Paprika, D. |
| Title |
Self-referent phenotype matching in a brood parasite: the armpit effect in brown-headed cowbirds (Molothrus ater) |
Type |
Journal Article |
| Year |
2000 |
Publication |
Animal Cognition |
Abbreviated Journal |
Anim. Cogn. |
| Volume |
3 |
Issue |
2 |
Pages |
113-117 |
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| Abstract |
Most birds and mammals learn characteristics of conspecifics from their parents and siblings. In interspecific brood parasites, however, early social learning could lead to species recognition errors because young are reared among heterospecifics. Conceivably, juvenile parasites might inspect and memorize aspects of their own phenotype, and later match features of encountered individuals to that template. We tested for such self-referent phenotype matching by manipulating feather colors of hand-reared fledglings (n = 21) of the parasitic brown-headed cowbird (Molothrus ater). In simultaneous choice trials (n = 6 trials/subject) between dyed and normal-colored adult females, juvenile cowbirds (< 2 months old) approached more quickly and associated preferentially with individuals that were colored similar to themselves. These preferences remained even when differences between the associative behaviors of juvenile males and females were controlled statistically. Our data imply that cowbirds incorporate their own plumage color into their recognition template. This provides the first evidence of self-referent phenotype matching through experimental manipulation of a recognition cue. |
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no |
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Equine Behaviour @ team @ |
Serial |
3309 |
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