| |
Records |
Links |
|
Author |
Bannasch, D.; Rinaldo, C.; Millon, L.; Latson, K.; Spangler, T.; Hubberty, S.; Galuppo, L.; Lowenstine, L. |
|
| |
Title |
SRY negative 64,XX intersex phenotype in an American saddlebred horse |
Type |
Journal Article |
| |
Year |
2007 |
Publication |
Veterinary Journal (London, England : 1997) |
Abbreviated Journal |
Vet J |
|
| |
Volume |
173 |
Issue  |
2 |
Pages |
437-439 |
|
| |
Keywords |
Animals; Female; Genitalia/abnormalities; Hermaphroditism/*veterinary; Horse Diseases/*diagnosis/genetics; Horses/*genetics/*physiology; Karyotyping; Phenotype; Sex Differentiation; Sex Differentiation Disorders/diagnosis/veterinary; Sex-Determining Region Y Protein/genetics/*metabolism |
|
| |
Abstract |
A female American saddlebred horse was presented for surgical correction of a possible pseudohermaphrodite condition. The horse had abnormal external genitalia and exhibited stallion-like behaviour. No evidence of uterine or ovarian tissue was identified on laparoscopic examination, but hypoplastic testicular-like tissue was removed, although this was found to contain no spermatogonia upon histopathological examination. A karyotype was performed and showed the normal chromosomal complement for a female horse (64,XX). Polymerase chain reaction to detect the SRY gene was negative in peripheral blood as well as the testicular-like tissue. This case represents the first report of an SRY negative XX-male sex reversal intersex phenotype, which is a potentially inherited condition, in an American saddlebred horse. |
|
| |
Address |
Department of Population Health and Reproduction, School of Veterinary Medicine, University of California, Davis, CA 95616, USA. dlbannasch@ucdavis.edu |
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
|
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
1090-0233 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
PMID:16386440 |
Approved |
no |
|
| |
Call Number |
|
Serial |
1882 |
|
| Permanent link to this record |
| |
|
| |
|
Author |
Quiroz-Rothe, E.; Novales, M.; Aguilera-Tejero, E.; Rivero, J.L.L. |
|
| |
Title |
Polysaccharide storage myopathy in the M. longissimus lumborum of showjumpers and dressage horses with back pain |
Type |
Journal Article |
| |
Year |
2002 |
Publication |
Equine Veterinary Journal |
Abbreviated Journal |
Equine Vet J |
|
| |
Volume |
34 |
Issue |
2 |
Pages |
171-176 |
|
| |
Keywords |
Amylases/analysis; Animals; Back Pain/etiology/*veterinary; Biopsy; Carbohydrate Metabolism, Inborn Errors/diagnosis/pathology/*veterinary; Diagnosis, Differential; Glycogen/analysis; Horse Diseases/*diagnosis/pathology; Horses; Microscopy, Electron; Muscle, Skeletal/pathology; Muscular Diseases/diagnosis/pathology/*veterinary; Polysaccharides/*metabolism; Rhabdomyolysis/diagnosis/pathology/veterinary |
|
| |
Abstract |
This study was designed to investigate whether horses with clinical signs of back pain due to suspected soft tissue injuries were affected by polysaccharide storage myopathy (PSSM). Diagnosis of PSSM in muscle biopsies obtained from the M. longissimus lumborum of 5 showjumpers and 4 dressage horses with a history of back pain is reported. M. longissimus lumborum biopsies of these horses were characterised histopathologically and in 3/9 cases also by electron microscopy. Observations were compared with M. gluteus biopsies of the same horses, and with M. gluteus biopsies obtained from 6 Standardbreds with recurrent exertional rhabdomyolysis and from 6 healthy trotters. M. longissimus biopsies from horses with back pain showed pathognomonic signs of PSSM, i.e. high glycogen and/or abnormal complex amylase-resistant polysaccharide deposits. Similar features were found in M. gluteus biopsies of the same horses. Sections of horses with rhabdomyolysis had increased PAS stain when compared with healthy horses, but did not show amylase-resistant material. Qualitative observations were corroborated by quantitative histochemistry (optical densities) of sections stained with PAS and amylase PAS. This study demonstrated the presence of PSSM in the M. longissimus of showjumpers and dressage horses with back pain and indicates that epaxial muscle biopsy is an option in diagnosing back problems in horses when clinical examination and imaging techniques do not provide a precise diagnosis. |
|
| |
Address |
Department of Comparative Anatomy, Faculty of Veterinary Science, University of Cordoba, Spain |
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
|
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
0425-1644 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
PMID:11905436 |
Approved |
no |
|
| |
Call Number |
Equine Behaviour @ team @ |
Serial |
3727 |
|
| Permanent link to this record |
