Records |
Author |
Branchi, I.; Bichler, Z.; Berger-Sweeney, J.; Ricceri, L. |
Title |
Animal models of mental retardation: from gene to cognitive function |
Type |
Journal Article |
Year |
2003 |
Publication |
Neuroscience and Biobehavioral Reviews |
Abbreviated Journal |
Neurosci Biobehav Rev |
Volume |
27 |
Issue ![sorted by Issue field, ascending order (up)](img/sort_asc.gif) |
1-2 |
Pages |
141-153 |
Keywords |
Animals; Animals, Genetically Modified/growth & development; Behavior/physiology; Behavior, Animal; Brain/*growth & development; Cognition/*physiology; *Disease Models, Animal; Environment; Genes; Genetic Diseases, Inborn/physiopathology; Humans; Mental Retardation/classification/*genetics/*physiopathology |
Abstract |
About 2-3% of all children are affected by mental retardation, and genetic conditions rank among the leading causes of mental retardation. Alterations in the information encoded by genes that regulate critical steps of brain development can disrupt the normal course of development, and have profound consequences on mental processes. Genetically modified mouse models have helped to elucidate the contribution of specific gene alterations and gene-environment interactions to the phenotype of several forms of mental retardation. Mouse models of several neurodevelopmental pathologies, such as Down and Rett syndromes and X-linked forms of mental retardation, have been developed. Because behavior is the ultimate output of brain, behavioral phenotyping of these models provides functional information that may not be detectable using molecular, cellular or histological evaluations. In particular, the study of ontogeny of behavior is recommended in mouse models of disorders having a developmental onset. Identifying the role of specific genes in neuropathologies provides a framework in which to understand key stages of human brain development, and provides a target for potential therapeutic intervention. |
Address |
Section of Behavioural Pathophysiology, Laboratorio di Fisiopatologia di Organo e di Sistema, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Roma, Italy. branchi@iss.it |
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English |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0149-7634 |
ISBN |
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Conference |
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Notes |
PMID:12732230 |
Approved |
no |
Call Number |
Equine Behaviour @ team @ |
Serial |
2805 |
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Author |
Clark, T.B.; Peterson, B.V.; Whitcomb, R.F.; Henegar, R.B.; Hackett, K.J.; Tully, J.G. |
Title |
Spiroplasmas in the Tabanidae |
Type |
Journal Article |
Year |
1984 |
Publication |
Israel Journal of Medical Sciences |
Abbreviated Journal |
Isr J Med Sci |
Volume |
20 |
Issue ![sorted by Issue field, ascending order (up)](img/sort_asc.gif) |
10 |
Pages |
1002-1005 |
Keywords |
Animals; Diptera/*microbiology/ultrastructure; Ecology; Female; Hemolymph/microbiology; Male; Maryland; North Carolina; Plants/microbiology; Spiroplasma/classification/*isolation & purification/physiology |
Abstract |
Spiroplasmas were observed in seven species of the family Tabanidae (horse flies and deer flies). This is the fifth family of the order Diptera now known to harbor spiroplasmas. Noncultivable spiroplasmas were seen in the hemolymph of three species of the genus Tabanus, and cultivable forms were isolated from the guts of six species in three genera. Isolates from T. calens and T. sulcifrons were serologically similar and closely related to a spiroplasma in the lampyrid beetle, Ellychnia corrusca. These three isolates represent a new serogroup. Isolates from Hybomitra lasiophthalma were related to Group IV strains, while those from T. nigrovittatus and Chrysops sp. both represented new serogroups. At least some tabanids probably acquire spiroplasmas from contaminated flower surfaces. The possibility of vertebrate reservoirs for some tabanid spiroplasmas remains an open question. |
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English |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0021-2180 |
ISBN |
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Medium |
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Notes |
PMID:6511308 |
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no |
Call Number |
Equine Behaviour @ team @ |
Serial |
2687 |
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Author |
Makarov, V.V.; Bakulov, I.A. |
Title |
[Zoopathogenic arboviruses, their systematics and ecology] |
Type |
Journal Article |
Year |
1975 |
Publication |
Veterinariia |
Abbreviated Journal |
Veterinariia |
Volume |
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Issue ![sorted by Issue field, ascending order (up)](img/sort_asc.gif) |
11 |
Pages |
39-41 |
Keywords |
Animals; Arboviruses/*classification/pathogenicity; Cattle; Deer; Ecology; Horses; Insect Vectors; Sheep; Swine; Turkeys; Viruses/*classification/pathogenicity |
Abstract |
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Language |
Russian |
Summary Language |
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Original Title |
Zoopatogennye arbovirusy--sistematika i ekologiia |
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Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0042-4846 |
ISBN |
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Conference |
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Notes |
PMID:814685 |
Approved |
no |
Call Number |
Equine Behaviour @ team @ |
Serial |
2703 |
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Author |
Satorov, S.S.; Orzuev, M.I. |
Title |
[Frequency of the isolation of staphylococci from domestic animals and strain identification] |
Type |
Journal Article |
Year |
1987 |
Publication |
Zhurnal Mikrobiologii, Epidemiologii, i Immunobiologii |
Abbreviated Journal |
Zh Mikrobiol Epidemiol Immunobiol |
Volume |
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Issue ![sorted by Issue field, ascending order (up)](img/sort_asc.gif) |
12 |
Pages |
37-39 |
Keywords |
Animals; Animals, Domestic/*microbiology; Bacteriophage Typing; Carrier State/microbiology/veterinary; Cats; Ecology; Goats; Horses; Perissodactyla; Sheep; Staphylococcal Infections/microbiology/veterinary; Staphylococcus/classification/*isolation & purification |
Abstract |
Staphylococci occur in donkeys more frequently than in other animals, and only from donkeys coagulase-negative staphylococci, characteristic of humans (S. hominis, S. capitis, S. cohnii), were isolated. Least frequently staphylococcal carrier state was registered in cats; in these animals only coagulase-negative strains were found to occur. From 30 donkeys coagulase-positive staphylococci belonging to 47 S. aureus strains were isolated. These strains differed from known ecological variants in their biological properties, thus suggesting the existence of S. aureus ecovar specific for donkeys. These strains did not coagulate human, bovine and ovine plasma, but coagulated rabbit plasma in 100% of cases and donkey plasma only in 53% of cases; at the same time they relatively often produced delta hemolysin, rarely phosphatase and hyaluronidase and never fibrinolysin. These strains were typed by KPC phages, mainly 116 and 117. |
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Language |
Russian |
Summary Language |
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Original Title |
Chastota vydeleniia stafilokokkov u domashnykh zhivotnykh i identifikatsiia shtammov |
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Edition |
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ISSN |
0372-9311 |
ISBN |
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Medium |
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Conference |
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Notes |
PMID:3445728 |
Approved |
no |
Call Number |
Equine Behaviour @ team @ |
Serial |
2676 |
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Author |
Jansen, T.; Forster, P.; Levine, M.A.; Oelke, H.; Hurles, M.; Renfrew, C.; Weber, J.; Olek, K. |
Title |
Mitochondrial DNA and the origins of the domestic horse |
Type |
Journal Article |
Year |
2002 |
Publication |
Proceedings of the National Academy of Sciences of the United States of America |
Abbreviated Journal |
Proc. Natl. Acad. Sci. U.S.A. |
Volume |
99 |
Issue ![sorted by Issue field, ascending order (up)](img/sort_asc.gif) |
16 |
Pages |
10905-10910 |
Keywords |
Animals; Animals, Domestic/classification/*genetics; Base Sequence; DNA, Complementary; *DNA, Mitochondrial; *Evolution, Molecular; Horses/classification/*genetics; Molecular Sequence Data; Phylogeny |
Abstract |
The place and date of the domestication of the horse has long been a matter for debate among archaeologists. To determine whether horses were domesticated from one or several ancestral horse populations, we sequenced the mitochondrial D-loop for 318 horses from 25 oriental and European breeds, including American mustangs. Adding these sequences to previously published data, the total comes to 652, the largest currently available database. From these sequences, a phylogenetic network was constructed that showed that most of the 93 different mitochondrial (mt)DNA types grouped into 17 distinct phylogenetic clusters. Several of the clusters correspond to breeds and/or geographic areas, notably cluster A2, which is specific to Przewalski's horses, cluster C1, which is distinctive for northern European ponies, and cluster D1, which is well represented in Iberian and northwest African breeds. A consideration of the horse mtDNA mutation rate together with the archaeological timeframe for domestication requires at least 77 successfully breeding mares recruited from the wild. The extensive genetic diversity of these 77 ancestral mares leads us to conclude that several distinct horse populations were involved in the domestication of the horse. |
Address |
Biopsytec Analytik GmbH, Marie-Curie-Strasse 1, 53359 Rheinbach, Germany. jansen@biopsytec.com |
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English |
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Series Issue |
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Edition |
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ISSN |
0027-8424 |
ISBN |
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Area |
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Conference |
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Notes |
PMID:12130666 |
Approved |
no |
Call Number |
refbase @ user @ |
Serial |
772 |
Permanent link to this record |
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Author |
Yamazaki, Y.; Shinohara, N.; Watanabe, S. |
Title |
Visual discrimination of normal and drug induced behavior in quails (Coturnix coturnix japonica) |
Type |
Journal Article |
Year |
2004 |
Publication |
Animal Cognition |
Abbreviated Journal |
Anim. Cogn. |
Volume |
7 |
Issue ![sorted by Issue field, ascending order (up)](img/sort_asc.gif) |
2 |
Pages |
128-132 |
Keywords |
Animals; Behavior, Animal/*drug effects; Classification; Coturnix/*physiology; *Discrimination Learning; *Generalization (Psychology); Ketamine/pharmacology; Male; Methamphetamine/pharmacology; *Pattern Recognition, Visual; Video Recording; Visual Perception |
Abstract |
The ability to discriminate the physical states of others could be an adaptive behavior, especially for social animals. For example, the ability to discriminate illness behavior would be helpful for avoiding spoiled foods. We report on an experiment with Japanese quails testing whether these birds can discriminate the physical states of conspecifics. The quails were trained to discriminate between moving video images of quails injected with psychoactive drugs and those in a normal (not injected) condition. Methamphetamine (stimulant) or ketamine (anesthetic) were used to produce drug-induced behaviors in conspecifics. The former induced hyperactive behavior and the latter hypoactive behavior. The subject quails could learn the discrimination and showed generalization to novel images of the drug-induced behaviors. They did not, however, show discriminative behavior according to the type and dosage of the drugs. Thus, they categorized the behavior not on the basis of degree of activity, but on the basis of abnormality. |
Address |
Biopsychologie, Institut fur Kognitive Neurowissenschaft, Fakultat fur Psychologie, Ruhr-Universitat Bochum, 44780 Bochum, Germany. yumyam@bio.psy.ruhr-uni-bochum.de |
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English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
1435-9448 |
ISBN |
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Medium |
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Area |
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Conference |
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Notes |
PMID:15069613 |
Approved |
no |
Call Number |
Equine Behaviour @ team @ |
Serial |
2527 |
Permanent link to this record |
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Author |
Goto, K.; Wills, A.J.; Lea, S.E.G. |
Title |
Global-feature classification can be acquired more rapidly than local-feature classification in both humans and pigeons |
Type |
Journal Article |
Year |
2004 |
Publication |
Animal Cognition |
Abbreviated Journal |
Anim. Cogn. |
Volume |
7 |
Issue ![sorted by Issue field, ascending order (up)](img/sort_asc.gif) |
2 |
Pages |
109-113 |
Keywords |
Adult; Animals; Behavior, Animal/physiology; *Classification; Columbidae/*physiology; *Discrimination Learning; Form Perception; Humans; *Mental Processes; *Pattern Recognition, Visual; Species Specificity |
Abstract |
When humans process visual stimuli, global information often takes precedence over local information. In contrast, some recent studies have pointed to a local precedence effect in both pigeons and nonhuman primates. In the experiment reported here, we compared the speed of acquisition of two different categorizations of the same four geometric figures. One categorization was on the basis of a local feature, the other on the basis of a readily apparent global feature. For both humans and pigeons, the global-feature categorization was acquired more rapidly. This result reinforces the conclusion that local information does not always take precedence over global information in nonhuman animals. |
Address |
School of Psychology, Washington Singer Laboratories, University of Exeter, EX4 4QG, Exeter, UK. K.Goto@exeter.ac.uk |
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English |
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ISSN |
1435-9448 |
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Conference |
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Notes |
PMID:15069610 |
Approved |
no |
Call Number |
Equine Behaviour @ team @ |
Serial |
2530 |
Permanent link to this record |
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Author |
Fortes, A.F.; Merchant, H.; Georgopoulos, A.P. |
Title |
Comparative and categorical spatial judgments in the monkey: “high” and “low” |
Type |
Journal Article |
Year |
2004 |
Publication |
Animal Cognition |
Abbreviated Journal |
Anim. Cogn. |
Volume |
7 |
Issue ![sorted by Issue field, ascending order (up)](img/sort_asc.gif) |
2 |
Pages |
101-108 |
Keywords |
Animals; *Classification; Cognition; *Discrimination Learning; Form Perception; Macaca mulatta/*parasitology; Male; *Pattern Recognition, Visual; Semantics; *Space Perception |
Abstract |
Adult human subjects can classify the height of an object as belonging to either of the “high” or “low” categories by utilizing an abstract concept of midline that divides the vertical dimension into two halves. Children lack this abstract concept of midline, do not have a sense that these categories are directional opposites, and their categorical and comparative usages of high(er) or low(er) are restricted to the corresponding poles. We investigated the abilities of a rhesus monkey to perform categorical judgments in space. We were also interested in the presence of the congruity effect (a decrease in response time when the objects compared are closer to the category pole) in the monkey. The presence of this phenomenon in the monkey would allow us to relate the behavior of the animal to the two major competing hypotheses that have been suggested to explain the congruity effect in humans: the analog and semantic models. The monkey was trained in delayed match-to-sample tasks in which it had to categorize objects as belonging to either a high or low category. The monkey was able to generate an abstract notion of midline in a fashion similar to that of adult human subjects. The congruity effect was also present in the monkey. These findings, taken together with the notion that monkeys are not considered to think in propositional terms, may favor an analog comparison model in the monkey. |
Address |
Brain Sciences Center, Veterans Affairs Medical Center, One Veterans Drive, Minneapolis, MN 55417, USA |
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ISSN |
1435-9448 |
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Notes |
PMID:15069609 |
Approved |
no |
Call Number |
Equine Behaviour @ team @ |
Serial |
2531 |
Permanent link to this record |
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Author |
Takai, S.; Narita, K.; Ando, K.; Tsubaki, S. |
Title |
Ecology of Rhodococcus (Corynebacterium) equi in soil on a horse-breeding farm |
Type |
Journal Article |
Year |
1986 |
Publication |
Veterinary Microbiology |
Abbreviated Journal |
Vet Microbiol |
Volume |
12 |
Issue ![sorted by Issue field, ascending order (up)](img/sort_asc.gif) |
2 |
Pages |
169-177 |
Keywords |
Actinomycetales/classification/*growth & development; Animals; Corynebacterium/classification/*growth & development; Feces/microbiology; Female; Horses; Serotyping; *Soil Microbiology |
Abstract |
The ecology of Rhodococcus (Corynebacterium) equi in soil was studied on a horse-breeding farm. R. equi was cultured from soil at a depth of 0, 10, and 20 cm on the six sites of the farm at monthly intervals for 10 months from March to December of 1983. The highest numbers of R. equi were found in the surface soil. The mean number of bacteria in soil samples at every depth increased remarkably from 0 or 10(2) to 10(4) colony-forming units (CFU) g-1 of soil in the middle of April, and later decreased gradually. R. equi inoculated into six soil exudate broths prepared from surface soils at separate sites yielded suspensions with different optical densities, indicating differences in growth. The distribution of serotypes in the soil was similar to that in the horses on the farm. These findings indicated that R. equi could multiply in the soil and flourish in the cycle existing between horses and their soil environment. |
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Edition |
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ISSN |
0378-1135 |
ISBN |
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Notes |
PMID:3750818 |
Approved |
no |
Call Number |
Equine Behaviour @ team @ |
Serial |
2683 |
Permanent link to this record |
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Author |
Stout, I.J.; Clifford, C.M.; Keirans, J.E.; Portman, R.W. |
Title |
Dermacentor variabilis (Say) (Acarina: Ixodidae) established in southeastern Washington and northern Idaho |
Type |
Journal Article |
Year |
1971 |
Publication |
Journal of Medical Entomology |
Abbreviated Journal |
J Med Entomol |
Volume |
8 |
Issue ![sorted by Issue field, ascending order (up)](img/sort_asc.gif) |
2 |
Pages |
143-147 |
Keywords |
Animals; Arthropod Vectors; Disease Reservoirs/*epidemiology; Dogs; Ecology; Female; Horses; Humans; Idaho; Larva; Male; Seasons; Sheep; Tick Infestations/*epidemiology/veterinary; Ticks/*classification; Washington; Zoonoses |
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English |
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Edition |
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ISSN |
0022-2585 |
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Notes |
PMID:5157834 |
Approved |
no |
Call Number |
Equine Behaviour @ team @ |
Serial |
2729 |
Permanent link to this record |