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Author Dowdle, W.R.; Schild, G.C.
Title Influenza: its antigenic variation and ecology Type Journal Article
Year 1976 Publication Bulletin of the Pan American Health Organization Abbreviated Journal Bull Pan Am Health Organ
Volume 10 Issue 3 Pages 193-195
Keywords Animals; *Antigens, Viral; Bird Diseases/microbiology; Birds; Hemagglutinins, Viral; Horse Diseases/microbiology; Horses; Humans; Influenza A virus/immunology/isolation & purification; Influenza, Human/epidemiology; Mutation; Neuraminidase/immunology; Orthomyxoviridae/enzymology/*immunology; Orthomyxoviridae Infections/microbiology/veterinary; Recombination, Genetic; Swine; Swine Diseases/microbiology
Abstract Influenza viruses have two surface antigens, the glycoprotein structures hemagglutinin (HA) and neuraminidase (NA). Antibodies to each of these are associated with immunity, but the structures themselves are antigenically variable. When an antigenic change is gradual over time it is referred to as a drift, while a sudden complete or major change in either or both antigens is termed a shift. The mechanism of antigenic drift is usually attributed to selection of preexisting mutants by pressure from increasing immunity in the human population. The mechanism of antigenic shift is less clear, but one tentative hypothesis is that shifts arise from mammalian or avian reservoirs, or through genetic recombination of human and animal influenza strains.
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Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN (up) 0085-4638 ISBN Medium
Area Expedition Conference
Notes PMID:187273 Approved no
Call Number Equine Behaviour @ team @ Serial 2700
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Author Brown, R.F.; Houpt, K.A.; Schryver, H.F.
Title Stimulation of food intake in horses by diazepam and promazine Type Journal Article
Year 1976 Publication Pharmacology, biochemistry, and behavior Abbreviated Journal Pharmacol Biochem Behav
Volume 5 Issue 4 Pages 495-497
Keywords Age Factors; Animals; Diazepam/*pharmacology; Diet; Feeding Behavior/*drug effects; Female; Horses/*physiology; Male; Promazine/*pharmacology; Stimulation, Chemical
Abstract In two adult horses doses of 0.02-0.03 mg/kg diazepam, intravenously, increased 1 hr intake 54-75% above control levels. Intake was stimulated when the diet was a high grain, calorically dense one and also when the diet was a high fiber, calorically dilute one. Two young rapidly growing weanling horses showed an even more pronounced stimulation of intake. Following diazepam 1 hr intake was increased 105-240% above control lelvels. Promazine at a dose of 0.5 mg/kg also stimulated intake in adult horses, but not as markedly as did diazepam. A transquilizer and a neuroleptic appear to have a stimulatory eff upon short-term intake in horses.
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Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN (up) 0091-3057 ISBN Medium
Area Expedition Conference
Notes PMID:1005496 Approved no
Call Number refbase @ user @ Serial 60
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Author Domjan, M.
Title Determinants of the enhancement of flavored-water intake by prior exposure Type Journal Article
Year 1976 Publication Journal of Experimental Psychology. Animal Behavior Processes Abbreviated Journal J Exp Psychol Anim Behav Process
Volume 2 Issue 1 Pages 17-27
Keywords Animals; Arousal; *Awareness; Behavior, Animal; *Cognition; *Drinking Behavior; Environment; Escape Reaction; Fear; Male; Rats; Saccharin/administration & dosage; *Taste; Thirst; Time Factors; Water Deprivation
Abstract The intake of a 2.0% sodium saccharin solution in rats was observed to increase as a function of both the number (Experiment 1) and the duration (Experiment 3) of prior periods of access to the saccharin flavor, but did not increase when subjects were maintained on a fluid deprivation procedure in the absence of saccharin exposure (Experiment 2). The enhancement of intake was further influenced by the schedule of saccharin preexposures in the absence of variations in the amount of solution tasted (Experiment 4). The effect was not a function of the opportunity for subjects to determine their own pattern of contact with the saccharin flavor, the opportunity for association of the flavor with hunger and thirst reduction, or the amount of saccharin swallowed during preexposure (Experiment 5). These results suggest that mere exposure to a flavored solution is sufficient to increase subsequent intakes. The phenomenon is discussed in terms of the attenuation of neophobia elicited by the novelty of flavored solutions.
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Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN (up) 0097-7403 ISBN Medium
Area Expedition Conference
Notes PMID:1249524 Approved no
Call Number Equine Behaviour @ team @ Serial 2790
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