| Records |
| Author |
Pepperberg, I.M. |
| Title |
In search of king Solomon's ring: cognitive and communicative studies of Grey parrots (Psittacus erithacus) |
Type |
Journal Article |
| Year |
2002 |
Publication |
Brain, behavior and evolution |
Abbreviated Journal |
Brain Behav Evol |
| Volume |
59 |
Issue |
1-2 |
Pages |
54-67 |
| Keywords |
*Animal Communication; Animals; Attention/physiology; Cognition/*physiology; Cues; Form Perception/physiology; Humans; Intelligence; Learning/physiology; Male; Models, Psychological; Parrots/*physiology; Psychomotor Performance/physiology; Reward; Social Behavior |
| Abstract |
During the past 24 years, I have used a modeling technique (M/R procedure) to train Grey parrots to use an allospecific code (English speech) referentially; I then use the code to test their cognitive abilities. The oldest bird, Alex, labels more than 50 different objects, 7 colors, 5 shapes, quantities to 6, 3 categories (color, shape, material) and uses 'no', 'come here', wanna go X' and 'want Y' (X and Y are appropriate location or item labels). He combines labels to identify, request, comment upon or refuse more than 100 items and to alter his environment. He processes queries to judge category, relative size, quantity, presence or absence of similarity/difference in attributes, and show label comprehension. He semantically separates labeling from requesting. He thus exhibits capacities once presumed limited to humans or nonhuman primates. Studies on this and other Greys show that parrots given training that lacks some aspect of input present in M/R protocols (reference, functionality, social interaction) fail to acquire referential English speech. Examining how input affects the extent to which parrots acquire an allospecific code may elucidate mechanisms of other forms of exceptional learning: learning unlikely in the normal course of development but that can occur under certain conditions. |
| Address |
The MIT Media Lab, Cambridge, Mass. 02139, USA. impepper@media.mit.edu |
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English |
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0006-8977 |
ISBN |
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Conference |
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| Notes |
PMID:12097860 |
Approved |
no |
| Call Number |
refbase @ user @ |
Serial |
579 |
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| Author |
Alexander, F.; Davies, M.E. |
| Title |
Studies on vitamin B12 in the horse |
Type |
Journal Article |
| Year |
1969 |
Publication |
The British veterinary journal |
Abbreviated Journal |
Br. Vet. J. |
| Volume |
125 |
Issue |
4 |
Pages |
169-176 |
| Keywords |
Animals; Biological Assay; Cattle; Chickens; Feces/analysis; Horses/*metabolism; Humans; Lactobacillus/metabolism; Rabbits; Rats; Sheep; Urine/analysis; Vitamin B 12/*analysis |
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English |
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Series Issue |
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Edition |
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| ISSN |
0007-1935 |
ISBN |
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Conference |
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| Notes |
PMID:5814055 |
Approved |
no |
| Call Number |
refbase @ user @ |
Serial |
116 |
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| Author |
Ganswindt, A.; Palme, R.; Heistermann, M.; Borragan, S.; Hodges, J.K. |
| Title |
Non-invasive assessment of adrenocortical function in the male African elephant (Loxodonta africana) and its relation to musth |
Type |
Journal Article |
| Year |
2003 |
Publication |
General and Comparative Endocrinology |
Abbreviated Journal |
Gen Comp Endocrinol |
| Volume |
134 |
Issue |
2 |
Pages |
156-166 |
| Keywords |
Adrenal Cortex/*metabolism/secretion; Adrenal Cortex Function Tests/methods/*veterinary; Adrenocorticotropic Hormone/physiology; Animals; Carbon Isotopes/diagnostic use; Chromatography, High Pressure Liquid/veterinary; Elephants/*metabolism/urine; Feces/*chemistry; Glucocorticoids/analysis/urine; Hydrocortisone/*analysis/diagnostic use/urine; Immunoenzyme Techniques/methods/veterinary; Male; Reproduction/physiology; Sexual Behavior, Animal/physiology; Stress, Psychological/diagnosis/*physiopathology; Testosterone/*analysis/diagnostic use/urine |
| Abstract |
Adult male elephants periodically show the phenomenon of musth, a condition associated with increased aggressiveness, restlessness, significant weight reduction and markedly elevated androgen levels. It has been suggested that musth-related behaviours are costly and that therefore musth may represent a form of physiological stress. In order to provide data on this largely unanswered question, the first aim of this study was to evaluate different assays for non-invasive assessment of adrenocortical function in the male African elephant by (i) characterizing the metabolism and excretion of [3H]cortisol (3H-C) and [14C]testosterone (14C-T) and (ii) using this information to evaluate the specificity of four antibodies for determination of excreted cortisol metabolites, particularly with respect to possible cross-reactions with androgen metabolites, and to assess their biological validity using an ACTH challenge test. Based on the methodology established, the second objective was to provide data on fecal cortisol metabolite concentrations in bulls during the musth and non-musth condition. 3H-C (1 mCi) and 14C-T (100 microCi) were injected simultaneously into a 16 year old male and all urine and feces collected for 30 and 86 h, respectively. The majority (82%) of cortisol metabolites was excreted into the urine, whereas testosterone metabolites were mainly (57%) excreted into the feces. Almost all radioactive metabolites recovered from urine were conjugated (86% 3H-C and 97% 14C-T). In contrast, 86% and >99% of the 3H-C and 14C-T metabolites recovered from feces consisted of unconjugated forms. HPLC separations indicated the presence of various metabolites of cortisol in both urine and feces, with cortisol being abundant in hydrolysed urine, but virtually absent in feces. Although all antibodies measured substantial amounts of immunoreactivity after HPLC separation of peak radioactive samples and detected an increase in glucocorticoid output following the ACTH challenge, only two (in feces against 3alpha,11-oxo-cortisol metabolites, measured by an 11-oxo-etiocholanolone-EIA and in urine against cortisol, measured by a cortisol-EIA) did not show substantial cross-reactivity with excreted 14C-T metabolites and could provide an acceptable degree of specificity for reliable assessment of glucocorticoid output from urine and feces. Based on these findings, concentrations of immunoreactive 3alpha,11-oxo-cortisol metabolites were determined in weekly fecal samples collected from four adult bulls over periods of 11-20 months to examine whether musth is associated with increased adrenal activity. Results showed that in each male levels of these cortisol metabolites were not elevated during periods of musth, suggesting that in the African elephant musth is generally not associated with marked elevations in glucocorticoid output. Given the complex nature of musth and the variety of factors that are likely to influence its manifestation, it is clear, however, that further studies, particularly on free-ranging animals, are needed before a possible relationship between musth and adrenal function can be resolved. This study also clearly illustrates the potential problems associated with cross-reacting metabolites of gonadal steroids in EIAs measuring glucocorticoid metabolites. This has to be taken into account when selecting assays and interpreting results of glucocorticoid metabolite analysis, not only for studies in the elephant but also in other species. |
| Address |
German Primate Centre, Department of Reproductive Biology, Kellnerweg 4, 37077 Gottingen, Germany. ganswindt@www.dpz.gdwg.de |
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Place of Publication |
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English |
Summary Language |
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Abbreviated Series Title |
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Series Issue |
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Edition |
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| ISSN |
0016-6480 |
ISBN |
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Medium |
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Expedition |
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Conference |
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| Notes |
PMID:14511986 |
Approved |
no |
| Call Number |
Equine Behaviour @ team @ |
Serial |
4085 |
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| Author |
Touma, C.; Palme, R.; Sachser, N. |
| Title |
Analyzing corticosterone metabolites in fecal samples of mice: a noninvasive technique to monitor stress hormones |
Type |
Journal Article |
| Year |
2004 |
Publication |
Hormones and Behavior |
Abbreviated Journal |
Horm Behav |
| Volume |
45 |
Issue |
1 |
Pages |
10-22 |
| Keywords |
Adrenal Cortex/drug effects; Adrenal Cortex Function Tests; Adrenocorticotropic Hormone/pharmacology; Analysis of Variance; Animals; Circadian Rhythm; Corticosterone/*analysis/metabolism; Dexamethasone/pharmacology; Feces/*chemistry; Female; Immunoenzyme Techniques/*methods; Male; Mice; Mice, Inbred C57BL; Models, Animal; Reproducibility of Results; Stress, Psychological/*metabolism |
| Abstract |
In small animals like mice, the monitoring of endocrine functions over time is constrained seriously by the adverse effects of blood sampling. Therefore, noninvasive techniques to monitor, for example, stress hormones in these animals are highly demanded in laboratory as well as in field research. The aim of our study was to evaluate the biological relevance of a recently developed technique to monitor stress hormone metabolites in fecal samples of laboratory mice. In total, six experiments were performed using six male and six female mice each. Two adrenocorticotropic hormone (ACTH) challenge tests, two dexamethasone (Dex) suppression tests and two control experiments [investigating effects of the injection procedure itself and the diurnal variation (DV) of glucocorticoids (GCs), respectively] were conducted. The experiments clearly demonstrated that pharmacological stimulation and suppression of adrenocortical activity was reflected accurately by means of corticosterone metabolite (CM) measurements in the feces of males and females. Furthermore, the technique proved sensitive enough to detect dosage-dependent effects of the ACTH/Dex treatment and facilitated to reveal profound effects of the injection procedure itself. Even the naturally occurring DV of GCs could be monitored reliably. Thus, our results confirm that measurement of fecal CM with the recently established 5alpha-pregnane-3beta,11beta,21-triol-20-one enzyme immunoassay is a very powerful tool to monitor adrenocortical activity in laboratory mice. Since mice represent the vast majority of all rodents used for research worldwide and the number of transgenic and knockout mice utilized as animal models is still increasing, this noninvasive technique can open new perspectives in biomedical and behavioral science. |
| Address |
Department of Behavioural Biology, University of Muenster, D-48149 Muenster, Germany. touma@uni-muenster.de |
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English |
Summary Language |
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Abbreviated Series Title |
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Series Issue |
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Edition |
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| ISSN |
0018-506X |
ISBN |
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Conference |
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| Notes |
PMID:14733887 |
Approved |
no |
| Call Number |
Equine Behaviour @ team @ |
Serial |
4084 |
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| Author |
Reimers, M.; Schwarzenberger, F.; Preuschoft, S. |
| Title |
Rehabilitation of research chimpanzees: stress and coping after long-term isolation |
Type |
Journal Article |
| Year |
2007 |
Publication |
Hormones and Behavior |
Abbreviated Journal |
Horm Behav |
| Volume |
51 |
Issue |
3 |
Pages |
428-435 |
| Keywords |
Adaptation, Psychological/*physiology; Animals; *Animals, Laboratory; Exploratory Behavior; Hydrocortisone/analysis/metabolism; Male; Models, Biological; *Pan troglodytes; Social Dominance; Social Environment; *Social Isolation/psychology; Stress/*rehabilitation/veterinary; Time |
| Abstract |
We report on the permanent retirement of chimpanzees from biomedical research and on resocialization after long-term social isolation. Our aim was to investigate to what extent behavioral and endocrine measures of stress in deprived laboratory chimpanzees can be improved by a more species-typical social life style. Personality in terms of novelty responses, social dominance after resocialization and hormonal stress susceptibility were affected by the onset of maternal separation of infant chimpanzees and duration of deprivation. Chimpanzees, who were separated from their mothers at a younger age and kept in isolation for more years appeared to be more timid personalities, less socially active, less dominant and more susceptible to stress, as compared to chimpanzees with a less severe deprivation history. However, permanent retirement from biomedical research in combination with therapeutic resocialization maximizing chimpanzees' situation control resulted in reduced fecal cortisol metabolite levels. Our results indicate that chimpanzees can recover from severe social deprivation, and may experience resocialization as less stressful than solitary housing. |
| Address |
Department of Natural Sciences, Institute of Biochemistry, University of Veterinary Medicine, Veterinarplatz 1, 1210 Vienna, Austria. reimers@wild-vet.at |
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English |
Summary Language |
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Abbreviated Series Title |
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Series Issue |
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Edition |
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0018-506X |
ISBN |
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Conference |
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| Notes |
PMID:17292368 |
Approved |
no |
| Call Number |
Equine Behaviour @ team @ |
Serial |
4188 |
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| Author |
Overli, O.; Korzan, W.J.; Hoglund, E.; Winberg, S.; Bollig, H.; Watt, M.; Forster, G.L.; Barton, B.A.; OVerli, E.; Renner, K.J.; Summers, C.H. |
| Title |
Stress coping style predicts aggression and social dominance in rainbow trout |
Type |
Journal Article |
| Year |
2004 |
Publication |
Hormones and Behavior |
Abbreviated Journal |
Horm Behav |
| Volume |
45 |
Issue |
4 |
Pages |
235-241 |
| Keywords |
Adaptation, Psychological/physiology; Aggression/*physiology; Animals; *Dominance-Subordination; Female; *Hierarchy, Social; Hydrocortisone/blood; Individuality; Male; Matched-Pair Analysis; Oncorhynchus mykiss/*physiology; Stress/*physiopathology |
| Abstract |
Social stress is frequently used as a model for studying the neuroendocrine mechanisms underlying stress-induced behavioral inhibition, depression, and fear conditioning. It has previously been shown that social subordination may result in increased glucocorticoid release and changes in brain signaling systems. However, it is still an open question which neuroendocrine and behavioral differences are causes, and which are consequences of social status. Using juvenile rainbow trout of similar size and with no apparent differences in social history, we demonstrate that the ability to win fights for social dominance can be predicted from the duration of a behavioral response to stress, in this case appetite inhibition after transfer to a new environment. Moreover, stress responsiveness in terms of confinement-induced changes in plasma cortisol was negatively correlated to aggressive behavior. Fish that exhibited lower cortisol responses to a standardized confinement test were markedly more aggressive when being placed in a dominant social position later in the study. These findings support the view that distinct behavioral-physiological stress coping styles are present in teleost fish, and these coping characteristics influence both social rank and levels of aggression. |
| Address |
Biology Department and Neuroscience Group, University of South Dakota, Vermillion, SD 57069, USA. oyvind.overli@bio.uio.no |
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English |
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0018-506X |
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| Notes |
PMID:15053939 |
Approved |
no |
| Call Number |
Equine Behaviour @ team @ |
Serial |
4192 |
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| Author |
Joubert, L.; Oudar, J.; Hannoun, C.; Beytout, D.; Corniou, B.; Guillon, J.C.; Panthier, R. |
| Title |
[Epidemiology of the West Nile virus: study of a focus in Camargue. IV. Meningo-encephalomyelitis of the horse] |
Type |
Journal Article |
| Year |
1970 |
Publication |
Annales de l'Institut Pasteur |
Abbreviated Journal |
Ann Inst Pasteur (Paris) |
| Volume |
118 |
Issue |
2 |
Pages |
239-247 |
| Keywords |
Animals; Ecology; Encephalitis Viruses/*isolation & purification; Encephalomyelitis, Equine/*epidemiology/immunology; France; Hemagglutination Inhibition Tests; Meningoencephalitis/*veterinary; Neurologic Manifestations; Serologic Tests |
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French |
Summary Language |
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Original Title |
Epidemiologie du virus West Nile: etude d'un foyer en Camargue. IV. La meningo-encephalomyelite du cheval |
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| ISSN |
0020-2444 |
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| Notes |
PMID:5461277 |
Approved |
no |
| Call Number |
Equine Behaviour @ team @ |
Serial |
2737 |
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| Author |
Rosa, P.A.J.; Azevedo, A.M.; Aires-Barros, M.R. |
| Title |
Application of central composite design to the optimisation of aqueous two-phase extraction of human antibodies |
Type |
Journal Article |
| Year |
2007 |
Publication |
Journal of Chromatography. A |
Abbreviated Journal |
J Chromatogr A |
| Volume |
1141 |
Issue |
1 |
Pages |
50-60 |
| Keywords |
Analysis of Variance; Animals; Antibodies/*chemistry/*isolation & purification; Buffers; Chemical Fractionation/*methods; Horses; Humans; Hydrophobicity; Isoelectric Point; Models, Biological; Molecular Weight; Myoglobin/chemistry/isolation & purification; Osmolar Concentration; Phase Transition; Polyethylene Glycols; Serum Albumin/chemistry/isolation & purification; Sodium Chloride |
| Abstract |
The partition of human antibodies in aqueous two-phase systems (ATPSs) of polyethylene glycol (PEG) and phosphate was systematically studied using first pure proteins systems and then an artificial mixture of proteins containing 1mg/ml human immunoglobulin G (IgG), 10mg/ml serum albumin and 2mg/ml myoglobin. Preliminary results obtained using pure proteins systems indicated that the PEG molecular weight and concentration, the pH value and the salts concentration had a pronounced effect on the partitioning behaviour of all proteins. For high ionic strengths and pH values higher than the isoelectric point (pI) of the contaminant proteins, IgG could be selectively recovered on the top phase. According to these results, a face centred composite design was performed in order to optimise the purification of IgG from the mixture of proteins. The optimal conditions for the isolation of IgG were observed for high concentrations of NaCl and low concentrations of both phase forming components. The best purification was achieved using an ATPS containing 8% (w/w) PEG 3350, 10% (w/w) phosphate pH 6 and 15% (w/w) NaCl. A recovery yield of 101+/-7%, a purity of 99+/-0% and a yield of native IgG of 97+/-4% were obtained. Back extraction studies of IgG to a new phosphate phase were performed and higher yields were obtained using 10% phosphate buffer at pH 6. The total extraction yield was 76% and the purity 100%. |
| Address |
IBB Institute for Biotechnology and Bioengineering, Centre for Biological and Chemical Engineering, Instituto Superior Tecnico, Av Rovisco Pais, 1049-001 Lisbon, Portugal |
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English |
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0021-9673 |
ISBN |
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Conference |
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| Notes |
PMID:17196214 |
Approved |
no |
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Serial |
1842 |
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| Author |
Nelson, W.A.; Keirans, J.E.; Bell, J.F.; Clifford, C.M. |
| Title |
Host-ectoparasite relationships |
Type |
Journal Article |
| Year |
1975 |
Publication |
Journal of Medical Entomology |
Abbreviated Journal |
J Med Entomol |
| Volume |
12 |
Issue |
2 |
Pages |
143-166 |
| Keywords |
Animal Nutrition Physiology; Animals; Anoplura/physiology; *Arthropods; Birds/parasitology; Chickens/parasitology; Dermacentor/parasitology; Diptera; Ecology; Feeding Behavior; Female; Horses/parasitology; Humans; Male; Mallophaga/physiology; Mice/parasitology; Mites/physiology; Reproduction; Sarcoptes scabiei/physiology; Sheep/parasitology; Skin/parasitology; Ticks/physiology; Toxins, Biological/toxicity; Trombiculidae/physiology |
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English |
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Abbreviated Series Title |
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0022-2585 |
ISBN |
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Conference |
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| Notes |
PMID:808617 |
Approved |
no |
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Equine Behaviour @ team @ |
Serial |
2704 |
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| Author |
Malek, E.A. |
| Title |
The life cycle of Gastrodiscus aegyptiacus (Cobbold, 1876) Looss, 1896 (Trematoda: Paramphistomatidae: Gastrodiscinae) |
Type |
Journal Article |
| Year |
1971 |
Publication |
The Journal of Parasitology |
Abbreviated Journal |
J Parasitol |
| Volume |
57 |
Issue |
5 |
Pages |
975-979 |
| Keywords |
Animals; Bulinus; *Disease Vectors; Ecology; Feces; Female; Horse Diseases/*etiology; Horses; Metamorphosis, Biological; Ovum; Parasite Egg Count; Perissodactyla; Sudan; Trematoda/anatomy & histology/growth & development; Trematode Infections/etiology/*veterinary |
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English |
Summary Language |
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Original Title |
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Series Title |
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Abbreviated Series Title |
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Series Issue |
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Edition |
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| ISSN |
0022-3395 |
ISBN |
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Medium |
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Expedition |
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Conference |
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| Notes |
PMID:5167379 |
Approved |
no |
| Call Number |
Equine Behaviour @ team @ |
Serial |
2726 |
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