| Records |
| Author |
Landaeta-Hernández, A. J.; Chenoweth, P. J.; Randles, R.; Littell, R.; Rae, O.; Chase, C. C. |
| Title |
Identifying the social dominance order in a mixed breed herd: a practical methodology |
Type |
Journal Article |
| Year |
2005 |
Publication |
Revista Científica |
Abbreviated Journal |
Revista Científica |
| Volume |
15 |
Issue |
2 |
Pages |
148-154 |
| Keywords |
Cattle, behavior, social organization |
| Abstract |
The major objective of this study was to identify a simple and accurate method of assessing differences in female social status. Three methods of estimating dominance value (DV) were compared in beef cows of three breed-types; Angus (A; n=10), Brahman (B; n=10), and Senepol (S; n=10). Cows were equitably assigned to two groups of fifteen each, allocated into separate pastures and containing equal number of animals by breed. Agonistic interactions were recorded for 45 d of study, in two 1 h periods during concentrate feeding using the method of competitive orders winner/loser. Methods of estimating DV included: I) Ratio between individuals dominated and total encountered, II) Ratio between encounters won to total encounters, III) Proportion of individuals dominated to total herdmates. Due to the different level of interactivity evidenced among animals as well as between and within social orders, method III with subsequent arc-sin transformation was considered as the most practical and accurate method for estimating DV and subsequent allocation of cows into a social dominance order. In addition, a breed effect was found on social dominance. Senepol cows obtained greater DV`s (1.24 ± 0.08) than Angus (0.97 ± 0.08; P<0.03) and Brahman cows (0.76 ± 0.08; P<0.005). |
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ISSN  |
0798-2259 |
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Approved |
yes |
| Call Number |
Equine Behaviour @ team @ |
Serial |
4753 |
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| Author |
Rehbinder, C.; Hau, J. |
| Title |
Quantification of cortisol, cortisol immunoreactive metabolites, and immunoglobulin A in serum, saliva, urine, and feces for noninvasive assessment of stress in reindeer |
Type |
Journal Article |
| Year |
2005 |
Publication |
Canadian Journal of Veterinary Research |
Abbreviated Journal |
Can J Vet Res |
| Volume |
70 |
Issue |
2 |
Pages |
151-154 |
| Keywords |
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| Abstract |
This study was designed to develop reliable methods for quantification of cortisol and cortisol immunoreactive metabolites (C-CIM) and immunoglobulin A (IgA) in reindeer serum, saliva, urine, and feces as tools for the objective noninvasive assessment of well-being and immunocompetence in reindeer. Although C-CIM was readily quantifiable by radioimmunoassay in serum, urine, and feces, the levels in saliva samples were low, rendering quantification unreliable. Whereas IgA concentrations were high in feces samples, they were much lower, albeit quantifiable, in serum and urine; the levels in saliva samples were too low for quantification with the use of an enzyme-linked immunosorbent assay that we developed. Further studies are in progress to validate the usefulness of fecal levels of C-CIM and IgA in the assessment of welfare in reindeer. |
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Canadian Veterinary Medical Association |
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Series Issue |
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Edition |
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| ISSN |
0830-9000 |
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no |
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Equine Behaviour @ team @ |
Serial |
5852 |
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| Author |
Traversa, D.; Otranto, D.; Iorio, R.; Giangaspero, A. |
| Title |
Molecular characterization of Thelazia lacrymalis (Nematoda, Spirurida) affecting equids: a tool for vector identification |
Type |
Journal Article |
| Year |
2005 |
Publication |
Molecular and Cellular Probes |
Abbreviated Journal |
Mol Cell Probes |
| Volume |
19 |
Issue |
4 |
Pages |
245-249 |
| Keywords |
Animals; Horse Diseases/parasitology; Horses/*parasitology; Insect Vectors/*parasitology; Muscidae/*parasitology; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Spirurida Infections/parasitology/veterinary; Thelazioidea/chemistry/*genetics |
| Abstract |
Equine thelaziosis caused by the eyeworm Thelazia lacrymalis is a parasitic disease transmitted by muscid flies. Although equine thelaziosis is known to have worldwide distribution, information on the epidemiology and presence of the intermediate hosts of T. lacrymalis is lacking. In the present work, a PCR-RFLP based assay on the first and/or second internal transcribed spacer (ITS1 and ITS2) of ribosomal DNA was developed for the detection of T. lacrymalis DNA in its putative vector(s). The sensitivity of the technique was also assessed. The restriction patterns obtained readily differentiated T. lacrymalis from four species of Musca (Diptera, Muscidae) (i.e. Musca autumnalis, Musca domestica, Musca larvipara and Musca osiris), which are potential vectors of equine eyeworms. The molecular assay presented herein is a useful tool to identify the intermediate host(s) of T. lacrymalis in natural conditions and to study its/their ecology and epidemiology. |
| Address |
Department of Biomedical Comparative Sciences, Faculty of Veterinary Medicine, University of Teramo, Piazza Aldo Moro 45, 64100 Teramo, Italy. dtraversa@unite.it |
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English |
Summary Language |
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Series Issue |
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Edition |
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| ISSN |
0890-8508 |
ISBN |
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Expedition |
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Conference |
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| Notes |
PMID:16038792 |
Approved |
no |
| Call Number |
Equine Behaviour @ team @ |
Serial |
2626 |
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| Author |
Nicol, C.J.; Adachi, M.; Akiyama, T.E.; Gonzalez, F.J. |
| Title |
PPARgamma in endothelial cells influences high fat diet-induced hypertension |
Type |
Journal Article |
| Year |
2005 |
Publication |
American journal of hypertension : journal of the American Society of Hypertension |
Abbreviated Journal |
Am J Hypertens |
| Volume |
18 |
Issue |
4 Pt 1 |
Pages |
549-556 |
| Keywords |
Administration, Oral; Animals; Antihypertensive Agents/pharmacology; Blood Pressure/drug effects; Diabetes Mellitus, Type 2/physiopathology; Dietary Fats/*administration & dosage/pharmacology; Dose-Response Relationship, Drug; Endothelial Cells/*metabolism; Female; Heart Rate/drug effects; Hypertension/*etiology; Ligands; Male; Mice; Mice, Knockout; PPAR gamma/*metabolism; Sodium Chloride/administration & dosage/pharmacology; Thiazolidinediones/pharmacology |
| Abstract |
BACKGROUND: Peroxisome proliferator-activated receptor gamma (PPARgamma) ligands improve human hypertension. However, the mechanism and site of this effect remains unknown, confounded by PPARgamma expression in many cell types, including endothelial cells (ECs). METHODS: To evaluate the vascular role of PPARgamma we used a conditional null mouse model. Specific disruption of PPARgamma in ECs was created by crossing Tie2-Cre+ transgenic (T2T+) and PPARgamma-floxed (fl/fl) mice to generate PPARgamma (fl/fl)T2T+ (PPARgamma E-null) mice. Conscious 8- to 12-week-old congenic PPARgamma (fl/fl)Cre- (wild type) and PPARgamma E-null mice were examined for changes in systolic blood pressure (BP) and heart rate (HR), untreated, after 2 months of salt-loading (drinking water), and after treatment for 3 months with high fat (HF) diet alone or supplemented during the last 2 weeks with rosiglitazone (3 mg/kg/d). RESULTS: Untreated PPARgamma E-nulls were phenotypically indistinguishable from wild-type littermates. However, compared to similarly treated wild types, HF-treated PPARgamma E-nulls had significantly elevated systolic BP not seen after normal diet or salt-loading. Despite sex-dependent baseline differences, salt-loaded and HF-treated PPARgamma E-nulls of either sex had significantly elevated HR versus wild types. Interestingly, rosiglitazone improved serum insulin levels, but not HF diet-induced hypertension, in PPARgamma E-null mice. CONCLUSIONS: These results suggest that PPARgamma in ECs not only is an important regulator of hypertension and HR under stressed conditions mimicking those arising in type 2 diabetics, but also mediates the antihypertensive effects of rosiglitazone. These data add evidence supporting a beneficial role for PPARgamma-specific ligands in the treatment of hypertension, and suggest therapeutic strategies targeting ECs may prove useful. |
| Address |
Laboratory of Metabolism, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA |
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English |
Summary Language |
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Series Title |
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Abbreviated Series Title |
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Series Issue |
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Edition |
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| ISSN |
0895-7061 |
ISBN |
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Medium |
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Expedition |
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Conference |
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| Notes |
PMID:15831367 |
Approved |
no |
| Call Number |
refbase @ user @ |
Serial |
69 |
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| Author |
Hedberg, Y.; Dalin, A.-M.; Ohagen, P.; Holm, K.R.; Kindahl, H. |
| Title |
Effect of oestrous-cycle stage on the response of mares in a novel object test and isolation test |
Type |
Journal Article |
| Year |
2005 |
Publication |
Reproduction in Domestic Animals = Zuchthygiene |
Abbreviated Journal |
Reprod Domest Anim |
| Volume |
40 |
Issue |
5 |
Pages |
480-488 |
| Keywords |
Animals; Behavior, Animal/*physiology; Cross-Over Studies; Diestrus/*physiology; Estrus/*physiology; Female; Heart Rate/*physiology; Horses/*physiology; Questionnaires |
| Abstract |
In various species, sex, hormonal treatments and oestrous-cycle stage have been shown to affect the animal's response in behavioural tests. Few such studies have been performed in the horse. The main aim of the present study was to investigate whether oestrous-cycle stage affects mares' response to a novel object test and isolation test and, in part, to study whether mares, assumed to suffer from oestrous-related behavioural problems, respond differently in these tests when compared with controls. Twelve mares were tested twice, in oestrus and dioestrus, in a crossover design. Seven behavioural and two heart rate variables were measured for the novel object test and two heart rate variables for the isolation test. Oestrous-cycle stage and whether a mare was classified as a 'problem' mare did not affect the mare's response. However, test order, i.e. the cycle stage a mare was tested in first, affected its reaction. This effect could partly be explained by significant differences between test occasions 1 and 2 in three behavioural variables and one heart rate variable (p < 0.05) in the novel object test. The mares explored the novel object more and had a higher mean heart rate in the first test. Exploring the novel object more could largely be attributed to those mares tested in dioestrus first, perhaps indicating that the mares in oestrus were less receptive to the novel object. The reason for the differences between test occasions could be an effect of learning or habituation. |
| Address |
Division of Comparative Reproduction, Obstetrics and Udder Health, Department of Clinical Sciences, Swedish University of Agricultural Sciences, Uppsala, Sweden. ylva.hedberg@kv.slu.se |
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English |
Summary Language |
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Original Title |
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Series Title |
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Abbreviated Series Title |
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Series Issue |
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Edition |
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| ISSN |
0936-6768 |
ISBN |
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Medium |
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Expedition |
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Conference |
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| Notes |
PMID:16149956 |
Approved |
no |
| Call Number |
Equine Behaviour @ team @ |
Serial |
5170 |
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| Author |
Maury, M.; Murphy, K.; Kumar, S.; Mauerer, A.; Lee, G. |
| Title |
Spray-drying of proteins: effects of sorbitol and trehalose on aggregation and FT-IR amide I spectrum of an immunoglobulin G |
Type |
Journal Article |
| Year |
2005 |
Publication |
European Journal of Pharmaceutics and Biopharmaceutics |
Abbreviated Journal |
Eur. J. Pharm. Biopharm. |
| Volume |
59 |
Issue |
2 |
Pages |
251-261 |
| Keywords |
Immunoglobulin; Spray-drying; Stabilization; Sorbitol; Trehalose; Water replacement |
| Abstract |
An immunoglobulin G (IgG) was spray-dried on a Büchi 190 laboratory spray-dryer at inlet and outlet air temperatures of 130 and 190°C, respectively. The IgG solution contains initially 115mg/ml IgG plus 50mg/ml sorbitol. After dialysis, at least 80% of low molecular weight component was removed. After spray-drying the dialyzed IgG and immediate redissolution of the powder, an increase in aggregates from 1 to 17% occurred. A major shift towards increase β-sheet structure was detected in the spray-dried solid, which, however, reverted to native structure on redissolution of the powder. A correlation between aggregation determined by size exclusion chromatography and alterations in secondary structure determined by Fourier transformation infra-red spectroscopy could not therefore be established. On spray-drying a non-dialyzed, sorbitol-containing IgG only some 0.7% aggregates were formed. The sorbitol is therefore evidently able to stabilize partially the IgG during the process of spray-drying. Addition of trehalose to the liquid feed produced quantitatively the same stabilizing action on the IgG during spray-drying as did the sorbitol. This finding again points towards a water replacement stabilization mechanism. The IgG spray-dried powder prepared from the dialyzed liquid feed showed continued substantial aggregation on dry storage at 25°C. This was substantially less in the non-dialyzed, sorbitol-containing spray-dried powder. Addition of trehalose to both dialyzed and non-dialyzed system produced substantial improvement in storage stability and reduction in aggregate formation in storage. The quantitative stabilizing effect of the trehalose was only slightly higher than that of the sorbitol. Taken together, these results indicate that both the sorbitol and trehalose stabilize the IgG primarily by a water replacement mechanism rather than by glassy immobilization. The relevance of this work is its questioning of the importance of the usually considered dominance of glassy stabilization of protein in dried systems of high glass transition temperature, such as trehalose. The low glass transition temperature sorbitol produces almost equal process and storage stability in this case. |
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Edition |
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0939-6411 |
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no |
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Equine Behaviour @ team @ |
Serial |
6515 |
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Papakostas, Y.G.; Daras, M.D.; Liappas, I.A.; Markianos, M. |
| Title |
Horse madness (hippomania) and hippophobia |
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Journal Article |
| Year |
2005 |
Publication |
History of Psychiatry |
Abbreviated Journal |
Hist Psychiatry |
| Volume |
16 |
Issue |
Pt 4 (no 64) |
Pages |
467-471 |
| Keywords |
Ancient Lands; Animals; Cattle; History, Ancient; Horse Diseases/*history; Horses; Humans; *Mythology |
| Abstract |
Anthropophagic horses have been described in classical mythology. From a current perspective, two such instances are worth mentioning and describing: Glaucus of Potniae, King of Efyra, and Diomedes, King of Thrace, who were both devoured by their horses. In both cases, the horses' extreme aggression and their subsequent anthropophagic behaviour were attributed to their madness (hippomania) induced by the custom of feeding them with flesh. The current problem of 'mad cow' disease (bovine spongiform encephalopathy) is apparently related to a similar feed pattern. Aggressive behaviour in horses can be triggered by both biological and psychological factors. In the cases cited here, it is rather unlikely that the former were the cause. On the other hand, the multiple abuses imposed on the horses, coupled with people's fantasies and largely unconscious fears (hippophobia), may possibly explain these mythological descriptions of 'horse-monsters'. |
| Address |
Athens University Medical School |
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English |
Summary Language |
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Original Title |
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Series Issue |
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Edition |
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0957-154X |
ISBN |
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| Notes |
PMID:16482685 |
Approved |
no |
| Call Number |
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Serial |
1876 |
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| Author |
Parr, L.A.; Waller, B.M.; Fugate, J. |
| Title |
Emotional communication in primates: implications for neurobiology |
Type |
Journal Article |
| Year |
2005 |
Publication |
Current Opinion in Neurobiology |
Abbreviated Journal |
Curr. Opin. Neurobiol. |
| Volume |
15 |
Issue |
6 |
Pages |
716-720 |
| Keywords |
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| Abstract |
The social brain hypothesis proposes that large neocortex size in Homonoids evolved to cope with the increasing demands of complex group living and greater numbers of interindividual relationships. Group living requires that individuals communicate effectively about environmental and internal events. Recent data have highlighted the complexity of chimpanzee communication, including graded facial expressions and referential vocalizations. Among Hominoids, elaborate facial communication is accompanied by specializations in brain areas controlling facial movement. Finally, the evolution of empathy, or emotional awareness, might have a neural basis in specialized cells in the neocortex, that is, spindle cells that have been associated with self-conscious emotions, and mirror neurons that have recently been shown to activate in response to communicative facial gestures. |
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Edition |
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0959-4388 |
ISBN |
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Approved |
no |
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Equine Behaviour @ team @ |
Serial |
5059 |
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Hare, B.; Plyusnina, I.; Ignacio, N.; Schepina, O.; Stepika, A.; Wrangham, R.; Trut, L. |
| Title |
Social cognitive evolution in captive foxes is a correlated by-product of experimental domestication |
Type |
Journal Article |
| Year |
2005 |
Publication |
Current biology : CB |
Abbreviated Journal |
Curr Biol |
| Volume |
15 |
Issue |
3 |
Pages |
226-230 |
| Keywords |
Animals; *Animals, Domestic; Cognition/*physiology; *Cues; *Evolution; Foxes/*physiology; *Selection (Genetics); Social Behavior; Species Specificity |
| Abstract |
Dogs have an unusual ability for reading human communicative gestures (e.g., pointing) in comparison to either nonhuman primates (including chimpanzees) or wolves . Although this unusual communicative ability seems to have evolved during domestication , it is unclear whether this evolution occurred as a result of direct selection for this ability, as previously hypothesized , or as a correlated by-product of selection against fear and aggression toward humans--as is the case with a number of morphological and physiological changes associated with domestication . We show here that fox kits from an experimental population selectively bred over 45 years to approach humans fearlessly and nonaggressively (i.e., experimentally domesticated) are not only as skillful as dog puppies in using human gestures but are also more skilled than fox kits from a second, control population not bred for tame behavior (critically, neither population of foxes was ever bred or tested for their ability to use human gestures) . These results suggest that sociocognitive evolution has occurred in the experimental foxes, and possibly domestic dogs, as a correlated by-product of selection on systems mediating fear and aggression, and it is likely the observed social cognitive evolution did not require direct selection for improved social cognitive ability. |
| Address |
Department of Anthropology, Harvard University, Cambridge, MA 02138, USA. hare@eva.mpg.de |
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English |
Summary Language |
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Series Issue |
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Edition |
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0960-9822 |
ISBN |
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Conference |
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| Notes |
PMID:15694305 |
Approved |
no |
| Call Number |
refbase @ user @ |
Serial |
594 |
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| Author |
Flack, J.C.; Krakauer, D.C.; de Waal, F.B.M. |
| Title |
Robustness mechanisms in primate societies: a perturbation study |
Type |
Journal Article |
| Year |
2005 |
Publication |
Proceedings. Biological sciences / The Royal Society |
Abbreviated Journal |
Proc Biol Sci |
| Volume |
272 |
Issue |
1568 |
Pages |
1091-1099 |
| Keywords |
Aggression/physiology; Animals; *Conflict (Psychology); Female; *Hierarchy, Social; Macaca nemestrina/*physiology; Male; *Models, Theoretical; Observation; *Social Behavior |
| Abstract |
Conflict management mechanisms have a direct, critical effect on system robustness because they mitigate conflict intensity and help repair damaged relationships. However, robustness mechanisms can also have indirect effects on system integrity by facilitating interactions among components. We explore the indirect role that conflict management mechanisms play in the maintenance of social system robustness, using a perturbation technique to 'knockout' components responsible for effective conflict management. We explore the effects of knockout on pigtailed macaque (Macaca nemestrina) social organization, using a captive group of 84 individuals. This system is ideal in addressing this question because there is heterogeneity in performance of conflict management. Consequently, conflict managers can be easily removed without disrupting other control structures. We find that powerful conflict managers are essential in maintaining social order for the benefit of all members of society. We show that knockout of components responsible for conflict management results in system destabilization by significantly increasing mean levels of conflict and aggression, decreasing socio-positive interaction and decreasing the operation of repair mechanisms. |
| Address |
Santa Fe Institute, NM 87501, USA. jflack@santafe.edu |
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English |
Summary Language |
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Original Title |
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Series Title |
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Abbreviated Series Title |
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Series Issue |
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Edition |
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| ISSN |
0962-8452 |
ISBN |
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Medium |
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Expedition |
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Conference |
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| Notes |
PMID:16024369 |
Approved |
no |
| Call Number |
refbase @ user @ |
Serial |
165 |
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