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Author Dunn, M.F.; Branlant, G.
Title Roles of zinc ion and reduced coenzyme in horse liver alcohol dehydrogenase catalysis. The mechanism of aldehyde activation Type Journal Article
Year 1975 Publication Biochemistry Abbreviated Journal Biochemistry
Volume 14 Issue 14 Pages (down) 3176-3182
Keywords *Alcohol Oxidoreductases/metabolism; Aldehydes/*pharmacology; Animals; Binding Sites; Enzyme Activation/drug effects; Horses; Hydrogen-Ion Concentration; Kinetics; Liver/enzymology; *NAD/analogs & derivatives/pharmacology; Oxidation-Reduction; Protein Binding; Spectrophotometry; Spectrophotometry, Ultraviolet; Temperature; *Zinc/pharmacology
Abstract 1,4,5,6-Tetrahydronicotinamide adenine dinucleotide (H2NADH) has been investigated as a reduced coenzyme analog in the reaction between trans-4-N,N-dimethylaminocinnamaldehyde (I) (lambdamax 398 nm, epsilonmax 3.15 X 10-4 M-minus 1 cm-minus 1) and the horse liver alcohol dehydrogenase-NADH complex. These equilibrium binding and temperature-jump kinetic studies establish the following. (i) Substitution of H2NADH for NADH limits reaction to the reversible formation of a new chromophoric species, lambdamax 468 nm, epsilonmax 5.8 x 10-4 M-minus 1 cm-minus 1. This chromophore is demonstrated to be structurally analogous to the transient intermediate formed during the reaction of I with the enzyme-NADH complex [Dunn, M. F., and Hutchison, J. S. (1973), Biochemistry 12, 4882]. (ii) The process of intermediate formation with the enzyme-NADH complex is independent of pH over the range 6.13-10.54. Although studies were limited to the pH range 5.98-8.72, a similar pH independence appears to hold for the H2NADH system. (iii) Within the ternary complex, I is bound within van der Waal's contact distance of the coenzyme nicotinamide ring. (iv) Formation of the transient intermediate does not involve covalent modification of coenzyme. Based on these findings, we conclude that zinc ion has a Lewis acid function in facilitating the chemical activation of the aldehyde carbonyl for reduction, and that reduced coenzyme plays a noncovalent effector role in this substrate activating step.
Address
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Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0006-2960 ISBN Medium
Area Expedition Conference
Notes PMID:238585 Approved no
Call Number Equine Behaviour @ team @ Serial 3817
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Author Ordakowski-Burk, A.L.; Quinn, R.W.; Shellem, T.A.; Vough, L.R.
Title Voluntary intake and digestibility of reed canarygrass and timothy hay fed to horses Type Journal Article
Year 2006 Publication Journal of Animal Science Abbreviated Journal J. Anim Sci.
Volume 84 Issue 11 Pages (down) 3104-3109
Keywords Animal Feed/*analysis; Animal Nutrition Physiology; Animals; Diet/*veterinary; Digestion/*physiology; Feeding Behavior/*physiology; Horses/*physiology; Male; Poaceae/*metabolism
Abstract Thousands of hectares of timothy (Phleum pretense L.) grown in the Mid-Atlantic region are infected by cereal rust mite (Abacarus hysterix) that causes discoloration and curling of leaves, decreased nutritional quality, and substantial decreases in yield. A decline in production of timothy hay can lower income for hay producers and cause horse owners to search for alternative hays. Low alkaloid reed canarygrass (Phalaris arundinacea L.) hay has potential as an alternative to timothy hay because it grows well in the Mid-Atlantic region, is believed to have a similar nutrient quality to timothy, and is not as susceptible to cereal rust mite. Eleven mature, stalled Thoroughbred geldings (549 +/- 12.1 kg) that were exercised daily were used to compare voluntary DMI and apparent nutrient DM digestibility of timothy and low-alkaloid Chiefton variety reed canarygrass hay. Horses were paired by age and BW and randomly assigned to timothy or reed canarygrass hay during a 14-d period to measure voluntary DMI followed by a 4-d period to measure apparent DM digestibility. Both hays met the minimum requirements for DE, CP, Ca, P, K, Fe, and Mn, but they did not meet the minimum requirements for Cu, Zn, and Na for horses at maintenance and averaging 550 kg of BW. Timothy hay seemed to have a lower CP concentration (14.4%) compared with reed canarygrass hay (17.1%) and a more desirable Ca:P ratio at 1.6:1 compared with 0.8:1 for reed canarygrass hay. Horses fed timothy consumed more hay (P <0.001) during the voluntary DMI period compared with horses fed reed canarygrass. Greater voluntary DMI of timothy occurred on d 1, 3, and 5 (P <0.05), but DMI was similar for other days. Apparent DM digestibility was greater in horses fed timothy hay by 9.6% compared with horses fed reed canarygrass hay (P <0.05). Horses fed timothy had greater DM digestibility of ADF (P = 0.001), NDF (P = 0.001), sugar (P = 0.05), and Ca (P = 0.001) but lower apparent DM digestibility of CP (P = 0.012) and crude fat (P = 0.004). Timothy hay was superior in voluntary DMI and apparent DM digestibility compared with low-alkaloid reed canarygrass hay fed to horses.
Address Department of Animal and Avian Sciences, University of Maryland, College Park 20742, USA. amyburk@umd.edu
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1525-3163 ISBN Medium
Area Expedition Conference
Notes PMID:17032805 Approved no
Call Number Equine Behaviour @ team @ Serial 4236
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Author Skedros, J.G.; Dayton, M.R.; Sybrowsky, C.L.; Bloebaum, R.D.; Bachus, K.N.
Title The influence of collagen fiber orientation and other histocompositional characteristics on the mechanical properties of equine cortical bone Type Journal Article
Year 2006 Publication The Journal of Experimental Biology Abbreviated Journal J Exp Biol
Volume 209 Issue Pt 15 Pages (down) 3025-3042
Keywords Animals; Biomechanics; Bone and Bones/*physiology; Collagen/*physiology; Forelimb; Horses/*physiology
Abstract This study examined relative influences of predominant collagen fiber orientation (CFO), mineralization (% ash), and other microstructural characteristics on the mechanical properties of equine cortical bone. Using strain-mode-specific (S-M-S) testing (compression testing of bone habitually loaded in compression; tension testing of bone habitually loaded in tension), the relative mechanical importance of CFO and other material characteristics were examined in equine third metacarpals (MC3s). This model was chosen since it had a consistent non-uniform strain distribution estimated by finite element analysis (FEA) near mid-diaphysis of a thoroughbred horse, net tension in the dorsal/lateral cortices and net compression in the palmar/medial cortices. Bone specimens from regions habitually loaded in tension or compression were: (1) tested to failure in both axial compression and tension in order to contrast S-M-S vs non-S-M-S behavior, and (2) analyzed for CFO, % ash, porosity, fractional area of secondary osteonal bone, osteon cross-sectional area, and population densities of secondary osteons and osteocyte lacunae. Multivariate multiple regression analyses revealed that in S-M-S compression testing, CFO most strongly influenced total energy (pre-yield elastic energy plus post-yield plastic energy); in S-M-S tension testing CFO most strongly influenced post-yield energy and total energy. CFO was less important in explaining S-M-S elastic modulus, and yield and ultimate stress. Therefore, in S-M-S loading CFO appears to be important in influencing energy absorption, whereas the other characteristics have a more dominant influence in elastic modulus, pre-yield behavior and strength. These data generally support the hypothesis that differentially affecting S-M-S energy absorption may be an important consequence of regional histocompositional heterogeneity in the equine MC3. Data inconsistent with the hypothesis, including the lack of highly longitudinal collagen in the dorsal-lateral ;tension' region, paradoxical histologic organization in some locations, and lack of significantly improved S-M-S properties in some locations, might reflect the absence of a similar habitual strain distribution in all bones. An alternative strain distribution based on in vivo strain measurements, without FEA, on non-Thoroughbreds showing net compression along the dorsal-palmar axis might be more characteristic of the habitual loading of some of the bones that we examined. In turn, some inconsistencies might also reflect the complex torsion/bending loading regime that the MC3 sustains when the animal undergoes a variety of gaits and activities, which may be representative of only a portion of our animals, again reflecting the possibility that not all of the bones examined had similar habitual loading histories.
Address Utah Bone and Joint Center, 5323 S. Woodrow Street #202, Salt Lake City, UT 84107, USA. jskedros@utahboneandjoint.com
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0022-0949 ISBN Medium
Area Expedition Conference
Notes PMID:16857886 Approved no
Call Number Serial 1868
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Author Pere, M.C.
Title Maternal and fetal blood levels of glucose, lactate, fructose, and insulin in the conscious pig Type Journal Article
Year 1995 Publication Journal of Animal Science Abbreviated Journal J. Anim Sci.
Volume 73 Issue 10 Pages (down) 2994-2999
Keywords Animals; Blood Glucose/*analysis; Catheterization/methods/veterinary; Consciousness/physiology; Female; Fetal Blood/*chemistry; Fructose/analysis/*blood; Insulin/analysis/*blood; Lactates/analysis/*blood; Pregnancy; Swine/*blood/physiology
Abstract To study nutrition and metabolism in the fetal pig, a chronic catheterization method was developed that allows blood sampling in arteries and veins, at both the umbilical and uterine sources, in the conscious, unstressed animal. A catheter was inserted in the fetal aorta through a femoral artery, and another one was introduced in the umbilical vein. A catheter was put in a femoral artery of the sow so that its end was in the abdominal aorta. A fourth catheter was placed in a uterine vein draining the fetoplacental unit studied. This procedure was applied to 18 Large White primiparous sows at 99 d of gestation. Blood samples were drawn simultaneously using the four catheters before a meal at 103 d of pregnancy, and glucose, insulin, lactate, and fructose were determinated. Glycemia was 2.5 times higher in the sow than in the fetus. The extraction coefficient of glucose by the fetus amounted to 14% of the umbilical supply. The insulin level in the fetal pig was very low ( < 5 microU/mL). Lactate and fructose seemed to originate from the placenta. Blood lactate was 2.6 times lower in the sow than in the fetus, and its extraction coefficient by the fetus amounted to 8%. Fructose in the fetal blood was 2.3 times higher than that of glucose. Fructose was not utilized by the pig fetus. The present results obtained in the fetal pig are comparable to the conclusions drawn from studies with other species.
Address Station de Recherches Porcines, Institut National de la Recherche Agronomique, Saint-Gilles, France
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0021-8812 ISBN Medium
Area Expedition Conference
Notes PMID:8617670 Approved no
Call Number Equine Behaviour @ team @ Serial 2751
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Author Owren, M.J.; Seyfarth, R.M.; Cheney, D.L.
Title The acoustic features of vowel-like grunt calls in chacma baboons (Papio cyncephalus ursinus): implications for production processes and functions Type Journal Article
Year 1997 Publication The Journal of the Acoustical Society of America Abbreviated Journal J Acoust Soc Am
Volume 101 Issue 5 Pt 1 Pages (down) 2951-2963
Keywords Animals; Female; *Papio; Sound Spectrography; *Vocalization, Animal
Abstract The acoustic features of 216 baboon grunts were investigated through analysis of field-recorded calls produced by identified females in known contexts. Analyses addressed two distinct questions: whether the acoustic features of these tonal sounds could be characterized using a source-filter approach and whether the acoustic features of grunts varied by individual caller and social context. Converging evidence indicated that grunts were produced through a combination of periodic laryngeal vibration and a stable vocal tract filter. Their acoustic properties closely resembled those of prototypical human vowel sounds. In general, variation in the acoustic features of the grunts was more strongly related to caller identity than to the social contexts of calling. However, two acoustic parameters, second formant frequency and overall spectral tilt, did vary consistently depending on whether the caller was interacting with an infant or participating in a group move. Nonetheless, in accordance with the general view that identity cueing is a compelling function in animal communication, it can be concluded that much of the observed variability in grunt acoustics is likely to be related to this aspect of signaling. Further, cues related to vocal tract filtering appear particularly likely to play an important role in identifying individual calling animals.
Address Department of Psychology, Reed College, Portland, Oregon 97202, USA. michael.owren@reed.edu
Corporate Author Thesis
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Language English Summary Language Original Title
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Series Volume Series Issue Edition
ISSN 0001-4966 ISBN Medium
Area Expedition Conference
Notes PMID:9165741 Approved no
Call Number refbase @ user @ Serial 698
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Author Swanson, J.C.
Title Farm animal well-being and intensive production systems Type Journal Article
Year 1995 Publication Journal of Animal Science Abbreviated Journal J. Anim Sci.
Volume 73 Issue 9 Pages (down) 2744-2751
Keywords Animal Husbandry/legislation & jurisprudence/*standards; Animal Rights/legislation & jurisprudence/standards; Animal Welfare/legislation & jurisprudence/*standards; Animals; Animals, Domestic/*growth & development/*physiology; Breeding/legislation & jurisprudence/*standards; Cattle; Chickens; Environment; Reproduction/physiology; Sheep; Swine
Abstract Animal welfare, or well-being, is a social issue with ethical, scientific, political, and aesthetic properties. Answering questions about the welfare of animals requires scientific definition, assessment, solutions, and public acceptance. With respect to the actual well-being of the animal, most issues are centered on how the animal “feels” when managed within a specific level of confinement, during special agricultural practices (e.g., tail docking, beak trimming, etc.) and handling. Questions of this nature may require exploration of animal cognition, motivation, perception, and emotional states in addition to more commonly recognized indicators of well-being. Several general approaches have emerged for solving problems concerning animal well-being in intensive production systems: environmental, genetic, and therapeutic. Environmental approaches involve modifying existing systems to accommodate specific welfare concerns or development of alternative systems. Genetic approaches involve changing the behavioral and (or) physiological nature of the animal to reduce or eliminate behaviors that are undesirable within intensive system. Therapeutic approaches of a physical (tail docking, beak trimming) and physiological (drug and nutritional therapy) nature bring both concern and promise with regard to the reduction of confinement stress. Finally, the recent focus on commodity quality assurance programs may indirectly provide benefits for animal well-being. Although research in the area of animal well-being will provide important information for better animal management, handling, care, and the physical design of intensive production systems there is still some uncertainty regarding public acceptance. The aesthetics of modern intensive production systems may have as much to do with public acceptance as with science.
Address Department of Animal Sciences and Industry, Kansas State University, Manhattan 66506, USA
Corporate Author Thesis
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Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0021-8812 ISBN Medium
Area Expedition Conference
Notes PMID:8582867 Approved no
Call Number Equine Behaviour @ team @ Serial 2752
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Author A. Lanata; A. Guidi; G. Valenza; P. Baragli; E. P. Scilingo
Title Quantitative heartbeat coupling measures in human-horse interaction Type Conference Article
Year 2016 Publication 2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) Abbreviated Journal 2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (E
Volume Issue Pages (down) 2696-2699
Keywords electrocardiography; medical signal processing; signal classification; time series; Dtw; Hrv; Mpc; Msc; complex biological systems; dynamic time warping; grooming; heart rate variability time series; heartbeat dynamics; human-horse dynamic interaction; magnitude squared coherence; magnitude-phase coupling; mean phase coherence; nearest mean classifier; quantitative heartbeat coupling; real human-animal interaction; time duration; visual-olfactory interaction; Coherence; Couplings; Electrocardiography; Heart rate variability; Horses; Protocols; Time series analysis
Abstract Abstract— We present a study focused on a quantitative estimation of a human-horse dynamic interaction. A set of measures based on magnitude and phase coupling between heartbeat dynamics of both humans and horses in three different conditions is reported: no interaction, visual/olfactory interaction and grooming. Specifically, Magnitude Squared Coherence (MSC), Mean Phase Coherence (MPC) and Dynamic Time Warping (DTW) have been used as estimators of the amount of coupling between human and horse through the analysis of their heart rate variability (HRV) time series in a group of eleven human subjects, and one horse. The rationale behind this study is that the interaction of two complex biological systems go towards a coupling process whose dynamical evolution is modulated by the kind and time duration of the interaction itself. We achieved a congruent and consistent

statistical significant difference for all of the three indices. Moreover, a Nearest Mean Classifier was able to recognize the three classes of interaction with an accuracy greater than 70%. Although preliminary, these encouraging results allow a discrimination of three distinct phases in a real human-animal interaction opening to the characterization of the empirically proven relationship between human and horse.
Address
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Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title 2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (E
Series Volume Series Issue Edition
ISSN 1557-170x ISBN Medium
Area Expedition Conference
Notes Approved no
Call Number Equine Behaviour @ team @ Serial 6175
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Author Dierenfeld, E.S.
Title Vitamin E in exotics: effects, evaluation and ecology Type Journal Article
Year 1994 Publication The Journal of Nutrition Abbreviated Journal J Nutr
Volume 124 Issue 12 Suppl Pages (down) 2579s-2581s
Keywords Animal Feed/*analysis; Animals; Animals, Zoo/blood/*metabolism; Antelopes/blood/metabolism; Birds/blood/metabolism; Deer/blood/metabolism; Elephants/blood/metabolism; Equidae/blood/metabolism; Perissodactyla/blood/metabolism; Vitamin E/*administration & dosage/analysis/blood; Vitamin E Deficiency/pathology/physiopathology/veterinary
Abstract The pathophysiology and lesions associated with vitamin E deficiency are similar between domestic and exotic species, and circulating plasma concentrations are also similar between comparable groups. However, many ecological variables must be considered for the most relevant comparisons. Tissue values of vitamin E, apart from plasma, are unknown for most exotics. Dietary vitamin E requirements of exotic species and domestics appear to differ; based on natural foodstuff analyses and clinical observations, between 50 and 200 mg vitamin E/kg DM are necessary to prevent vitamin E deficiency, 5- to 10-fold higher than current livestock recommendations.
Address Department of Nutrition, Wildlife Health Center, Wildlife Conservation Society, Bronx, NY 10460
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Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0022-3166 ISBN Medium
Area Expedition Conference
Notes PMID:7996243 Approved no
Call Number Equine Behaviour @ team @ Serial 2661
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Author Kida, H.
Title [Ecology of influenza viruses in animals and the mechanism of emergence of new pandemic strains] Type Journal Article
Year 1997 Publication Nippon Rinsho. Japanese Journal of Clinical Medicine Abbreviated Journal Nippon Rinsho
Volume 55 Issue 10 Pages (down) 2521-2526
Keywords Animals; Bird Diseases/transmission; Birds; Horse Diseases/transmission; Horses; Humans; Influenza, Human/transmission/*veterinary; Swine; Swine Diseases/transmission; Zoonoses
Abstract Ecological studies on influenza viruses revealed that the hemagglutinin genes are introduced into new pandemic strains from viruses circulating in migratory ducks through domestic ducks and pigs in southern China. Experimental infection of pigs with 38 avian influenza virus strains with H1-H13 hemagglutinins showed that at least one strain of each HA subtype replicated in the upper respiratory tract of pigs. Co-infection of pigs with a swine virus and with an avian virus generated reassortant viruses. The results indicate that avian viruses of any subtype can contribute genes in the generation of reassortants. Virological surveillance revealed that influenza viruses in waterfowl reservoir are perpetuated year-by-year in the frozen lake water while ducks are absent.
Address Department of Disease Control, Hokkaido University Graduate School of Veterinary Medicine
Corporate Author Thesis
Publisher Place of Publication Editor
Language Japanese Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0047-1852 ISBN Medium
Area Expedition Conference
Notes PMID:9360367 Approved no
Call Number Equine Behaviour @ team @ Serial 2654
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Author Seghrouchni, M.; Elkasraoui, H.; Piro, M.; Alyakine, H.; Bouayad, H.; Chakir, J.; Tligui, N.; Elallali, K.; Azrib, R.
Title Osteoarticular radiographic findings of the distal forelimbs in Tbourida Horses Type Journal Article
Year 2019 Publication Heliyon Abbreviated Journal
Volume 5 Issue 9 Pages (down) e02514
Keywords Animal science; Pathophysiology; Animal behavior; Animal breeding; Veterinary medicine; Veterinary science; Horse; Radiographic findings; Forelimb; X-ray; Tbourida
Abstract Tbourida is a traditional Moroccan equestrian sport in which 15 horses gallop 200 m in a line while riders fire into the sky with muskets. The stop is the finale and representative demands of this equestrian event. Such particular sudden stop after a fast gallop requires a hyperextension of the metacarpophalangeal joint. Indeed, it is well known that Tbourida show predisposes horses to different injuries of the hard and soft tissues of the distal forelimbs. Yet, there is a paucity of research that examined such lesions. The aim of the present study was to investigate for the first time the type and the prevalence of osteoarticular findings in the distal forelimbs of Tbourida horses using radiographic images. The study was conducted on 127 Tbourida horses aged between 2.5 and 15 years old with 6-year-old horses being the most affected. Data analysis showed that 93,7% of horses exhibit degenerative joint lesions of the fetlock, 86,6% showed ossification of the ungual cartilage, 78,7% had enthesophytes associated with the deep digital flexor tendons, 81,1% had enthesophytes associated with the suspensory ligament branches, and 19,6% showed a particular exostosis on the first phalanx. This large number of lesions reflects how this sport is difficult for horses and also argues that animals are suffering from a lack of welfare and care in their husbandry management.
Address
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ISSN 2405-8440 ISBN Medium
Area Expedition Conference
Notes Approved no
Call Number Equine Behaviour @ team @ Serial 6672
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