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Author |
Alexander, F. |
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Title |
A study of parotid salivation in the horse |
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Journal Article |
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Year |
1966 |
Publication |
The Journal of physiology |
Abbreviated Journal |
J Physiol |
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Volume |
184 |
Issue |
3 |
Pages |
646-656 |
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Keywords |
Animals; Atropine/*pharmacology; Bicarbonates/metabolism; Calcium/metabolism; Chlorides/metabolism; Horses; Mastication/*physiology; Parotid Gland/*physiology; Pilocarpine/*pharmacology; Potassium/metabolism; Salivation/*drug effects; Sodium/metabolism; Tetracaine/*pharmacology |
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0022-3751 |
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PMID:5963737 |
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refbase @ user @ |
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119 |
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Author |
Alexander, F.; Ash, R.W. |
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Title |
The effect of emotion and hormones on the concentration of glucose and eosinophils in horse blood |
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Journal Article |
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Year |
1955 |
Publication |
The Journal of physiology |
Abbreviated Journal |
J Physiol |
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Volume |
130 |
Issue |
3 |
Pages |
703-710 |
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Keywords |
Blood Glucose/*drug effects; Eosinophils/*drug effects; Leukocyte Count/*drug effects; *ACTH/effects; *BLOOD SUGAR/effect of drugs on; *EOSINOPHIL COUNT/effect of drugs on; *EPINEPHRINE/effects; *HISTAMINE/effects; *INSULIN/effects; *STRESS/experimental |
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0022-3751 |
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PMID:13278929 |
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refbase @ user @ |
Serial |
122 |
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Author |
Alexander, F. |
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Title |
The effects of some humoral agents on the horse ileum |
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Journal Article |
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Year |
1952 |
Publication |
British journal of pharmacology and chemotherapy |
Abbreviated Journal |
Br J Pharmacol Chemother |
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Volume |
7 |
Issue |
1 |
Pages |
25-32 |
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Keywords |
Ileum/*drug effects; *HORMONES/effects; *ILEUM/effect of drugs on |
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0366-0826 |
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PMID:14904899 |
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refbase @ user @ |
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126 |
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Author |
Weik, H.; Altmann, J. |
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Title |
The effect of L(+)-lactate on rat and horse adipose tissue in vitro |
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Journal Article |
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Year |
1972 |
Publication |
Zentralblatt fur Veterinarmedizin. Reihe A |
Abbreviated Journal |
Zentralbl Veterinarmed A |
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Volume |
19 |
Issue |
6 |
Pages |
514-518 |
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Keywords |
Adipose Tissue/analysis/*drug effects; Animals; Fatty Acids, Nonesterified; Glycerol/metabolism; Horses; Lactates/*pharmacology; Lipid Metabolism; Male; Rats |
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0514-7158 |
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Notes |
PMID:4626300 |
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no |
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Call Number |
refbase @ user @ |
Serial |
132 |
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Author |
Turner, J.W.J.; Kirkpatrick, J.F. |
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Title |
Androgens, behaviour and fertility control in feral stallions |
Type |
Journal Article |
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Year |
1982 |
Publication |
Journal of reproduction and fertility. Supplement |
Abbreviated Journal |
J Reprod Fertil Suppl |
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Volume |
32 |
Issue |
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Pages |
79-87 |
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Keywords |
Animals; Animals, Wild; Copulation/drug effects; Female; *Fertility/drug effects; Horses/*physiology; Male; Periodicity; Pregnancy; Seasons; *Sexual Behavior, Animal/drug effects; Sexual Maturation; Sperm Count; Sperm Motility/drug effects; Testosterone/*blood/pharmacology |
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Abstract |
This field study of feral stallions in Montana and Idaho examines and correlates the seasonal pattern of plasma androgens and specific sociosexual behaviour and reports the effect of a long-acting androgenic steroid on this behaviour and on fertility. Plasma testosterone was measured by competitive protein binding assay in samples obtained by jugular venepuncture from captured animals. In samples taken from 34 sexually mature stallions in 6 different months during the year, a definite seasonal pattern in testosterone was present, with a peak in May (3.04 +/- 0.63 ng/ml) and a nadir in December (1.55 +/- 0.34 ng/ml). Values were less than 2.0 ng/ml in non-breeding months and greater than 2.4 ng/ml in breeding months. Behavioural endpoints measured were (1) stallion scent marking in response to elimination by mares (elimination marking), (2) mounting and (3) copulation. The frequencies of each of these endpoints followed closely the seasonal pattern seen for plasma androgens. In the fertility study microcapsulated testosterone propionate (microTP) was administered i.m. to 10 harem stud stallions 3 months before the 1980 breeding season. In these stallions and in 10 control harem studs, the above behavioural endpoints were examined in the 1980 and 1981 breeding seasons, and foal counts were made in 1981. There were no direct inhibitory or stimulatory effects of microTP treatment on any of the behavioural endpoints in either year. In 1981 foals were produced in 87.5% of the control bands and 28.4% of the microTP-treated bands. These results indicate that microencapsulated testosterone propionate can provide effective fertility control in feral horses without causing significant alterations in sociosexual behaviour. |
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ISSN |
0449-3087 |
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Notes |
PMID:6962905 |
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no |
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Call Number |
refbase @ user @ |
Serial |
138 |
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Author |
Lyda, R.O.; Hall, J.R.; Kirkpatrick, J.F. |
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Title |
A comparison of Freund's Complete and Freund's Modified Adjuvants used with a contraceptive vaccine in wild horses (Equus caballus) |
Type |
Journal Article |
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Year |
2005 |
Publication |
Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians |
Abbreviated Journal |
J Zoo Wildl Med |
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Volume |
36 |
Issue |
4 |
Pages |
610-616 |
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Keywords |
Animals; Antibody Formation; Contraception, Immunologic/*veterinary; Estrus/drug effects; Female; Freund's Adjuvant/administration & dosage/adverse effects/*immunology; Horses/immunology/*physiology; *Vaccines, Contraceptive; Zona Pellucida/*immunology |
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Abstract |
Fifteen captive wild mares (Equus caballus) were treated with porcine zona pellucida contraceptive vaccine and either Freund's Complete Adjuvant (n = 7) or Freund's Modified Adjuvant (n = 8). All mares received a booster inoculation of porcine zona pellucida plus Freund's Incomplete Adjuvant a month later. Anti-porcine zona pellucida antibodies were measured over 10 mo following the initial inoculation. There were no significant differences in antibody titers at any point during the 10 mo, and seven of the eight mares in the Freund's Modified Adjuvant group were above the 60% level at the end of the study, which is considered to be the contraceptive threshold for horses. There were no significant differences in titers between pregnant and nonpregnant horses, nor was there a significant correlation between age and titers. One local injection site reaction occurred after booster treatment with Freund's Incomplete Adjuvant, and 11 healthy foals were born during the course of the study. These data suggest that Freund's Modified Adjuvant is an acceptable substitute for Freund's Complete Adjuvant in certain free-ranging and captive wildlife species. |
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Address |
Science and Conservation Center, 2100 South Shiloh Road, Billings, Montana 59106, USA |
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English |
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ISSN |
1042-7260 |
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Notes |
PMID:17312717 |
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no |
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Call Number |
refbase @ user @ |
Serial |
139 |
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Author |
Kirkpatrick, J.F.; Liu, I.M.; Turner, J.W.J.; Naugle, R.; Keiper, R. |
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Title |
Long-term effects of porcine zonae pellucidae immunocontraception on ovarian function in feral horses (Equus caballus) |
Type |
Journal Article |
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Year |
1992 |
Publication |
Journal of reproduction and fertility |
Abbreviated Journal |
J Reprod Fertil |
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Volume |
94 |
Issue |
2 |
Pages |
437-444 |
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Keywords |
Animals; Contraception, Immunologic/*veterinary; *Egg Proteins; Estrogens, Conjugated (USP)/urine; Female; Glycoproteins/*pharmacology; Horses/immunology/*physiology; *Membrane Glycoproteins; Ovary/drug effects/*physiology; Progesterone/metabolism; *Receptors, Cell Surface; Swine/immunology; Time Factors; Zona Pellucida/*immunology |
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Abstract |
Ten feral mares free-roaming in Maryland, USA, were inoculated with porcine zonae pellucidae (PZP) protein before the breeding season for three consecutive years (1988-90). Ovarian function was monitored for 51 days during the peak of the breeding season after the third annual PZP inoculation, in seven of these mares and in four untreated control mares, by means of urinary oestrone conjugates and nonspecific progesterone metabolites. None of the ten inoculated mares became pregnant in 1990, compared with 55% of 20 control mares, which included two of the four monitored for ovarian function. Three of the untreated mares demonstrated apparent normal ovarian activity, characterized by preovulatory oestrogen peaks, concurrent progesterone nadirs at ovulation, breeding activity, and luteal-phase progesterone increases after ovulation. Two of the seven monitored PZP-treated mares demonstrated ovulatory cycles that did not result in conception. One was pregnant as a result of conception in 1989 and demonstrated a normal, late-gestation, endocrine profile. The remaining four PZP-treated mares revealed no evidence of ovulation, and urinary oestrogen concentrations were significantly depressed. The experiments indicated that (i) a third consecutive annual PZP booster inoculation is greater than 90% effective in preventing pregnancies in mares and (ii) three consecutive years of PZP treatment may interfere with normal ovarian function as shown by markedly depressed oestrogen secretion. |
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Deaconess Research Institute, Billings, MT 59102 |
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0022-4251 |
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Notes |
PMID:1317449 |
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no |
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Call Number |
refbase @ user @ |
Serial |
145 |
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Author |
Henning, J.M.; Zentall, T.R. |
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Title |
Imitation, social facilitation, and the effects of ACTH 4-10 on rats' bar-pressing behavior |
Type |
Journal Article |
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Year |
1981 |
Publication |
The American journal of psychology |
Abbreviated Journal |
Am J Psychol |
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Volume |
94 |
Issue |
1 |
Pages |
125-134 |
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Keywords |
Adrenocorticotropic Hormone/*pharmacology; Animals; Conditioning, Operant/*drug effects; Dose-Response Relationship, Drug; Extinction, Psychological/drug effects; Imitative Behavior/*drug effects; Male; Peptide Fragments/*pharmacology; Rats; *Social Facilitation |
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Abstract |
The effects of ACTH 4-10 on rats' imitation learning was examined during the acquisition and extinction of a bar-press response for water reinforcement. Rats were exposed to either a bar-pressing conspecific (OB), an experimentally naive conspecific (ON), or an empty box (OE) during bar-press acquisition. In a factorial design, each rat was then exposed to one of the same three conditions during extinction. An 80 mcg dose of ACTH 4-10 was administered to half of the rats in each group prior to observation. Performance differences during acquisition were generally small, but significant performance differences during extinction were found. Social facilitation was indicated by the finding that rats extinguished in the presence of a conspecific exhibited significantly greater resistance to extinction than rats extinguished in the presence of an empty box. An imitation effect was also found. Rats that observed a bar-pressing conspecific during both acquisition and extinction (group OB-OB) showed significantly greater resistance top extinction than did groups OB-ON, CB-OE, or OE-OE. There were no significant effects of the hormone, however, relative to saline controls. |
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ISSN |
0002-9556 |
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Notes |
PMID:6263117 |
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no |
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Call Number |
refbase @ user @ |
Serial |
267 |
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Author |
Madigan, J.E.; Bell, S.A. |
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Title |
Owner survey of headshaking in horses |
Type |
Journal Article |
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Year |
2001 |
Publication |
Journal of the American Veterinary Medical Association |
Abbreviated Journal |
J Am Vet Med Assoc |
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Volume |
219 |
Issue |
3 |
Pages |
334-337 |
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Keywords |
Animals; Anti-Allergic Agents/*therapeutic use; *Behavior, Animal/drug effects; Cyproheptadine/*therapeutic use; Data Collection; Diagnosis, Differential; Female; Horse Diseases/diagnosis/drug therapy/*etiology; Horses; Humans; Male; Questionnaires; Seasons |
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Abstract |
OBJECTIVE: To determine signalment, history, clinical signs, duration, seasonality, and response to various treatments reported by owners for headshaking in horses. DESIGN: Owner survey. ANIMALS: 109 horses with headshaking. PROCEDURE: Owners of affected horses completed a survey questionnaire. RESULTS: 78 affected horses were geldings, 29 were mares, and 2 were stallions. Mean age of onset was 9 years. Headshaking in 64 horses had a seasonal component, and for most horses, headshaking began in spring and ceased in late summer or fall. The most common clinical signs were shaking the head in a vertical plane, acting like an insect was flying up the nostril, snorting excessively, rubbing the muzzle on objects, having an anxious expression while headshaking, worsening of clinical signs with exposure to sunlight, and improvement of clinical signs at night. Treatment with antihistamines, nonsteroidal anti-inflammatory drugs, corticosteroids, antimicrobials, fly control, chiropractic, and acupuncture had limited success. Sixty-one horses had been treated with cyproheptadine; 43 had moderate to substantial improvement. CONCLUSIONS AND CLINICAL RELEVANCE: Headshaking may have many causes. A large subset of horses have similar clinical signs including shaking the head in a vertical plane, acting as if an insect were flying up the nostrils, and rubbing the muzzle on objects. Seasonality and worsening of clinical signs with exposure to light are also common features of this syndrome. Geldings and Thoroughbreds appear to be overrepresented. Cyproheptadine treatment was beneficial in more than two thirds of treated horses. |
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Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis 95616, USA |
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0003-1488 |
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PMID:11497047 |
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no |
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Call Number |
refbase @ user @ |
Serial |
1916 |
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Author |
Madigan, J.E.; Kortz, G.; Murphy, C.; Rodger, L. |
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Title |
Photic headshaking in the horse: 7 cases |
Type |
Journal Article |
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Year |
1995 |
Publication |
Equine Veterinary Journal |
Abbreviated Journal |
Equine Vet J |
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Volume |
27 |
Issue |
4 |
Pages |
306-311 |
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Keywords |
Animals; Anti-Allergic Agents/therapeutic use; *Behavior, Animal; Cyproheptadine/therapeutic use; Female; *Head; Horse Diseases/drug therapy/*etiology; Horses; Light/*adverse effects; Male; Movement Disorders/drug therapy/etiology/*veterinary |
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Abstract |
Seven horses with headshaking are described. No physical abnormalities were detected in any of the cases. Six of these horses had onset of clinical signs in the spring. The role of light was assessed by application of a blindfold or dark grey lens to the eyes, covering the eyes with a face mask and observing the horse in total darkness outdoors. Cessation of headshaking was observed with blindfolding (5/5 horses), night darkness outdoors (4/4 horses) and use of grey lenses (2/3 horses). Outdoor behaviour suggested efforts to avoid light in 4/4 cases. The photic sneeze in man is suggested as a putative mechanism for equine headshaking. Five of 7 horses had improvement with cyproheptadine treatment (0.3 mg/kg bwt b.i.d.). Headshaking developed within 2 calendar weeks of the same date for 3 consecutive years in one horse. Neuropharmacological alterations associated with photoperiod mechanisms leading to optic trigeminal summation are suggested as possible reasons for spring onset of headshaking. |
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Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California-Davis 95616-8737, USA |
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0425-1644 |
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PMID:8536668 |
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no |
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Call Number |
refbase @ user @ |
Serial |
1940 |
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