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Author Trim, C.M.; Moore, J.N.; Clark, E.S.
Title Renal effects of dopamine infusion in conscious horses Type Journal Article
Year 1989 Publication Equine veterinary journal. Supplement Abbreviated Journal Equine Vet J Suppl
Volume Issue 7 Pages 124-128
Keywords Animals; Blood Pressure/drug effects/physiology; Consciousness/*physiology; Creatinine/blood; Dopamine/administration & dosage/*pharmacology; Dose-Response Relationship, Drug; Female; Heart Rate/drug effects/physiology; Horses/*physiology; Infusions, Intravenous/veterinary; Kidney/blood supply/*drug effects/physiology; Osmolar Concentration; Potassium/blood; Random Allocation; Regional Blood Flow/drug effects/physiology; Renal Artery/drug effects/physiology/ultrasonography; Sodium/blood; Time Factors; Ultrasonography/methods/veterinary; Urination/physiology
Abstract An ultrasonic flow probe was implanted around a branch of the left renal artery in five horses. The effects of dopamine were studied in the unsedated horses 10 days after surgery. Three experiments, separated by at least two days, were performed in random order on each horse. In two experiments, dopamine was infused intravenously for 60 mins at either 2.5 and 5.0 micrograms/kg bodyweight (bwt)/min. Saline was infused for 60 mins before and after each infusion, and for 180 mins in the third experiment as a control. Renal blood flow increased during administration of dopamine at both dose rates (P = 0.0001). Urine volume increased (P = 0.055), and osmolality decreased (P < 0.05), with infusion of dopamine at 5.0 micrograms/kg bwt/min. Arterial blood pressure and heart rate were not significantly affected. Fractional excretions of sodium and potassium were not significantly changed with dopamine infusion. The higher dopamine dose rate was accompanied by dysrhythmias in some horses.
Address (down) Department of Large Animal Medicine, College of Veterinary Medicine, University of Georgia, Athens 30602, USA
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Notes PMID:9118094 Approved no
Call Number refbase @ user @ Serial 99
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Author Doherty, T.J.; Frazier, D.L.
Title Effect of intravenous lidocaine on halothane minimum alveolar concentration in ponies Type Journal Article
Year 1998 Publication Equine veterinary journal Abbreviated Journal Equine Vet J
Volume 30 Issue 4 Pages 300-303
Keywords Anesthetics/administration & dosage/blood/*pharmacology; Anesthetics, Inhalation/administration & dosage/*analysis; Animals; Consciousness/drug effects; Dose-Response Relationship, Drug; Halothane/administration & dosage/*analysis; Horses/*physiology; Infusions, Intravenous/veterinary; Lidocaine/administration & dosage/blood/*pharmacology; Male
Abstract This study investigated the effect of lidocaine i.v. on halothane minimum alveolar concentration (MAC) in ponies. Six ponies were anaesthetised with thiopentone and succinylcholine, intubated and anaesthesia maintained with halothane. Ventilation was controlled and blood pressure maintained within clinically acceptable limits. Following a 2 h equilibration period, baseline halothane MAC was determined. The ponies were then given a loading dose of lidocaine (2.5 or 5 mg/kg bwt) or saline over 5 min, followed by a constant infusion of lidocaine (50 or 100 microg/kg/min, or saline, respectively). The halothane MAC was redetermined after a 60 min infusion of lidocaine or saline. The baseline halothane MAC for the control group was mean +/- s.d. 0.94 +/- 0.03%, and no significant decrease occurred following saline infusion. Lidocaine decreased halothane MAC in a dose-dependent fashion (r = 0.86; P < 0.0003). The results indicate that i.v. lidocaine may have a role in equine anaesthesia.
Address (down) Department of Large Animal Clinical Sciences, University of Tennessee, College of Veterinary Medicine, Knoxville 37901-1071, USA
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Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0425-1644 ISBN Medium
Area Expedition Conference
Notes PMID:9705112 Approved no
Call Number refbase @ user @ Serial 95
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Author Gácsi, M.; Kara, E.; Belényi, B.; Topál, J.; Miklósi, Á.
Title The effect of development and individual differences in pointing comprehension of dogs Type Journal Article
Year 2009 Publication Animal Cognition Abbreviated Journal Anim. Cogn.
Volume 12 Issue 3 Pages 471-479
Keywords Age Factors; Analysis of Variance; Animals; *Association Learning; Attention; Chi-Square Distribution; Choice Behavior; *Comprehension; *Concept Formation; Dogs/*psychology; Female; *Gestures; Humans; Male; Orientation; Statistics, Nonparametric
Abstract In spite of the rather different procedures actually used in comparative studies to test the ability of different species to rely on the human pointing gesture, there is no debate on the high performance of dogs in such tasks. Very little is known, however, on the course through which they acquire this ability or the probable factors influencing the process. Important developmental questions have remained unsolved and also some methodological concerns should be addressed before we can convincingly argue for one interpretation or another. In this study we tested 180 dogs of different age (from 2 months to adults) to investigate their performance in the human distal momentary pointing gesture. The results, analyzed at both the group and the individual levels, showed no difference in the performance according to age, indicating that in dogs the comprehension of the human pointing may require only very limited and rapid early learning to fully develop. Interestingly, neither the keeping conditions nor the time spent in active interaction with the owner, and not even some special (agility) training for using human visual cues, had significant effect on the success and explained individual differences. The performance of the dogs was rather stable over time: during the 20 trials within a session and even when subsamples of different age were repeatedly tested. Considering that in spite of the general success at the group level, more than half of the dogs were not successful at the individual level, we revealed alternative “decision-making rules” other than following the pointing gesture of the experimenter.
Address (down) Department of Ethology, Eotvos University, Budapest, Hungary. gm.art@t-online.hu
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Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1435-9456 ISBN Medium
Area Expedition Conference
Notes PMID:19130102 Approved no
Call Number Equine Behaviour @ team @ Serial 4969
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Author Santamaria, S.; Bobbert, M.F.; Back, W.; Barneveld, A.; van Weeren, P.R.
Title Effect of early training on the jumping technique of horses Type Journal Article
Year 2005 Publication American Journal of Veterinary Research Abbreviated Journal Am J Vet Res
Volume 66 Issue 3 Pages 418-424
Keywords Age Factors; Analysis of Variance; Animals; Biomechanics; Forelimb/physiology; Gait/*physiology; Hindlimb/physiology; Horses/growth & development/*physiology; Locomotion/*physiology; Models, Biological; Physical Conditioning, Animal/*methods
Abstract OBJECTIVE: To investigate the effects of early training for jumping by comparing the jumping technique of horses that had received early training with that of horses raised conventionally. ANIMALS: 40 Dutch Warmblood horses. PROCEDURE: The horses were analyzed kinematically during free jumping at 6 months of age. Subsequently, they were allocated into a control group that was raised conventionally and an experimental group that received 30 months of early training starting at 6 months of age. At 4 years of age, after a period of rest in pasture and a short period of training with a rider, both groups were analyzed kinematically during free jumping. Subsequently, both groups started a 1-year intensive training for jumping, and at 5 years of age, they were again analyzed kinematically during free jumping. In addition, the horses competed in a puissance competition to test maximal performance. RESULTS: Whereas there were no differences in jumping technique between experimental and control horses at 6 months of age, at 4 years, the experimental horses jumped in a more effective manner than the control horses; they raised their center of gravity less yet cleared more fences successfully than the control horses. However, at 5 years of age, these differences were not detected. Furthermore, the experimental horses did not perform better than the control horses in the puissance competition. CONCLUSIONS AND CLINICAL RELEVANCE: Specific training for jumping of horses at an early age is unnecessary because the effects on jumping technique and jumping capacity are not permanent.
Address (down) Department of Equine Sciences, Faculty of Veterinary Medicine, Utrecht University, NL-3584 CM Utrecht, The Netherlands
Corporate Author Thesis
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Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0002-9645 ISBN Medium
Area Expedition Conference
Notes PMID:15822585 Approved no
Call Number Equine Behaviour @ team @ Serial 4037
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Author Vlamings, P.H.J.M.; Uher, J.; Call, J.
Title How the great apes (Pan troglodytes, Pongo pygmaeus, Pan paniscus, and Gorilla gorilla) perform on the reversed contingency task: the effects of food quantity and food visibility Type Journal Article
Year 2006 Publication Journal of Experimental Psychology. Animal Behavior Processes Abbreviated Journal J Exp Psychol Anim Behav Process
Volume 32 Issue 1 Pages 60-70
Keywords Age Factors; Animals; Behavior, Animal/physiology; Cognition; Conditioning (Psychology); Female; *Food; Gorilla gorilla/*psychology; *Learning; Male; Pan paniscus/*psychology; Pan troglodytes/*psychology; Pongo pygmaeus/*psychology; *Visual Perception
Abstract S. T. Boysen and G. G. Berntson (1995) found that chimpanzees performed poorly on a reversed contingency task in which they had to point to the smaller of 2 food quantities to acquire the larger quantity. The authors compared the performance of 4 great ape species (Pan troglodytes, Pongo pygmaeus, Pan paniscus, and Gorilla gorilla) on the reversed contingency task while manipulating food quantity (0-4 or 1-4) and food visibility (visible pairs or covered pairs). Results showed no systematic species differences but large individual differences. Some individuals of each species were able to solve the reversed contingency task. Both quantity and visibility of the food items had a significant effect on performance. Subjects performed better when the disparity between quantities was smaller and the quantities were not directly visible.
Address (down) Department of Developmental and Comparative Psychology, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany. p.vlamings@psychology.unimaas.nl
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Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0097-7403 ISBN Medium
Area Expedition Conference
Notes PMID:16435965 Approved no
Call Number Equine Behaviour @ team @ Serial 2765
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Author Morales, J.L.; Manchado, M.; Vivo, J.; Galisteo, A.M.; Aguera, E.; Miro, F.
Title Angular kinematic patterns of limbs in elite and riding horses at trot Type Journal Article
Year 1998 Publication Equine Veterinary Journal Abbreviated Journal Equine Vet J
Volume 30 Issue 6 Pages 528-533
Keywords Animals; Biomechanics; Breeding; Extremities/*physiology; Gait/*physiology; Horses/*physiology; Image Processing, Computer-Assisted; Joints/*physiology; Male; Video Recording
Abstract Normal speed videography was used to determine the angular parameters of 28 Spanish Thoroughbreds at trot. Horses were divided into 3 groups: Group UT, comprising 9 animals (provided by the VII National Stud, Cordoba, Spain) which had undergone no specific training programme and which were hand led at the trot; Group T, formed by 19 horses considered to be highly bred and trained, and which were also hand led; and Group RT, comprising the same horses as the latter group but this time trotted by a rider. Each animal was filmed 6 times from the right-hand side, using a Hi8 (25 Hz) video camera. Angular parameters for fore- and hindlimb joints were measured in each stride from computer-grabbed frames and entered into a spreadsheet for calculation; parameters included maximum and minimum angles, range of motion, and angles at landing, lift off and maximum hoof height; the times at which maximum angle, minimum angle, lift off and maximum hoof height occurred were calculated as percentages of total stride duration. Stride velocity (mean [s.d.]) was 4.01 (0.62), 3.60 (0.34) and 3.07 (0.36) m/s for Groups UT, T and RT, respectively. Data were then compared between Groups UT-T and Groups T-RT. Compared with Group UT, horses from Group T featured a shorter stance percentage (P<0.001) in both fore- and hindlimbs. The range of motion in forelimbs was smaller (P<0.05), due to lower retraction (P<0.001); moreover, maximum retraction appeared earlier (P<0.05). Greater scapular inclination was in evidence (P<0.05) and the shoulder joint extended further (P<0.05). Fore- and hind fetlock joints revealed a relatively shorter hyperextension period during the stance phase (P<0.01). Compared with Group T, horses from Group RT had a longer stance percentage, with belated maximum retraction of the fore- and hindlimbs. The range of movement in scapular inclination was greater (P<0.05), due to a smaller minimum angle (P<0.01), and the shoulder joint flexed more (P<0.05). The elbow joint extended more and for longer during the stance phase. Initial extension of the hip joint (P<0.05) and tarsus (P<0.001) lasted longer. The carpal and fore and hind fetlock joints recorded relatively longer hyperextension times, in addition to greater hyperextension during the stance phase. The results from the present study suggest that rider-effect must be taken in consideration when well gaited horses are selected for dressage purposes.
Address (down) Department of Compared Anatomy and Pathology, University of Cordoba, Veterinary Faculty, Spain
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Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0425-1644 ISBN Medium
Area Expedition Conference
Notes PMID:9844972 Approved no
Call Number Equine Behaviour @ team @ Serial 3734
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Author Pritchard, J.C.; Barr, A.R.S.; Whay, H.R.
Title Validity of a behavioural measure of heat stress and a skin tent test for dehydration in working horses and donkeys Type
Year 2006 Publication Equine veterinary journal Abbreviated Journal Equine Vet J
Volume 38 Issue 5 Pages 433-438
Keywords Age Factors; Animal Welfare; Animals; Behavior, Animal/physiology; Body Temperature/*physiology; Body Weight/physiology; Case-Control Studies; Dehydration/diagnosis/pathology/*veterinary; Drinking; *Equidae; Female; Heat Stress Disorders/diagnosis/physiopathology/*veterinary; Horse Diseases/*diagnosis/pathology; Horses; Hypovolemia/diagnosis/physiopathology/veterinary; Male; Osmolar Concentration; Pakistan; Respiration; Skin/*pathology; Species Specificity; Work
Abstract REASONS FOR PERFORMING STUDY: Dehydration and heat stress are serious welfare issues for equids working in developing countries. There is a lack of any standardised method or validated interpretation of the skin tent test in horses and donkeys. Owners of dehydrated and heat-stressed animals often depend on veterinary examination for identification of these conditions, leading to delays in treatment and unnecessary reliance on external sources to effect welfare improvement. OBJECTIVES: To validate a standardised skin tent test for dehydration and a behavioural measure of heat stress in working equids; and to examine the effect of heat stress and dehydration on tripping and staggering behaviour. METHODS: The study was carried out on 130 working horses and donkeys in Pakistan. Associations between skin tent and blood parameters (packed cell volume [PCV], serum total protein [TP], serum osmolality), clinical parameters, resting and drinking behaviour were examined. Heat stress behaviour (increased respiratory rate and depth, head nodding, flared nostrils, apathy) was observed in conjunction with rectal temperature. Tripping and staggering were assessed using a simple obstacle course. RESULTS: In both species, heat stress behaviour was significantly associated with increased rectal temperature (P<0.001). A positive skin tent test was not significantly associated with PCV or TP, although in donkeys it was significantly associated with lower serum osmolality (P<0.001). More animals age >15 years had a positive skin tent than those in younger age groups (P = 0.037). Very thin horses were more likely to have a positive skin tent than those in thin or moderate condition (P = 0.028). There was no significant correlation between skin tent and tripping or staggering in either species. CONCLUSIONS AND POTENTIAL RELEVANCE: Heat stress behaviour is related to increased body temperature in working horses and donkeys. Owners may use this to make judgements regarding rest and cooling, precluding the need to seek veterinary attention. The skin tent test for dehydration used in this study did not show a significant relationship with PCV or TP. However, the use of blood parameters to validate the skin tent test may be confounded by anaemia, hypoproteinaemia or electrolyte depletion. Alternative methods are needed to confirm or refute the validity of the skin tent test in working equids.
Address (down) Department of Clinical Veterinary Science, University of Bristol, Langford, UK
Corporate Author Thesis
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Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0425-1644 ISBN Medium
Area Expedition Conference
Notes PMID:16986604 Approved no
Call Number Serial 1784
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Author Nicol, C.J.
Title Development, direction, and damage limitation: social learning in domestic fowl Type Journal Article
Year 2004 Publication Learning & behavior : a Psychonomic Society publication Abbreviated Journal Learn Behav
Volume 32 Issue 1 Pages 72-81
Keywords Adaptation, Psychological; Age Factors; Animals; Behavior, Animal; *Chickens; *Feeding Behavior; *Food Preferences; *Imitative Behavior; Imprinting (Psychology); *Learning; Maternal Behavior; Reinforcement (Psychology); *Social Environment; *Social Facilitation
Abstract This review highlights two areas of particular interest in the study of social learning in fowl. First, the role of social learning in the development of feeding and foraging behavior in young chicks and older birds is described. The role of the hen as a demonstrator and possible teacher is considered, and the subsequent social influence of brood mates and other companions on food avoidance and food preference learning is discussed. Second, the way in which work on domestic fowl has contributed to an understanding of the importance of directed social learning is examined. The well-characterized hierarchical social organization of small chicken flocks has been used to design studies which demonstrate that the probability of social transmission is strongly influenced by social relationships between birds. The practical implications of understanding the role of social learning in the spread of injurious behaviors in this economically important species are briefly considered.
Address (down) Department of Clinical Veterinary Science, University of Bristol, Langford, Bristol, England. c.j.nicol@bristol.ac.uk
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Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
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ISSN 1543-4494 ISBN Medium
Area Expedition Conference
Notes PMID:15161142 Approved no
Call Number refbase @ user @ Serial 75
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Author Lucas, Z.; Raeside, J.I.; Betteridge, K.J.
Title Non-invasive assessment of the incidences of pregnancy and pregnancy loss in the feral horses of Sable Island Type Journal Article
Year 1991 Publication Journal of Reproduction and Fertility. Supplement Abbreviated Journal J Reprod Fertil Suppl
Volume 44 Issue Pages 479-488
Keywords Abortion, Veterinary/*epidemiology; Animals; Animals, Wild/*physiology; Atlantic Islands; Estrogens/analysis; Feces/chemistry; Female; Fertilization; Gestational Age; Horse Diseases/*epidemiology; Horses; Incidence; Pregnancy; *Pregnancy, Animal
Abstract Field observations of 400 totally unmanaged feral horses on Sable Island, Nova Scotia, were complemented by oestrogen determinations in faecal samples from 154 identified females over a 4-year period (454 mare-years). Of mares that were sampled throughout the year and subsequently produced foals, 92.1% exhibited elevated faecal oestrogens between 15 October and 30 March. The results confirm that faecal oestrogens are a useful indicator of pregnancy after approximately 120 days gestation. Distribution of foaling resembled that seen in other feral populations, with 95% of births occurring from April through July. The foaling rate for mares aged 3 years or older was 62.0%, with 50.7% of mares foaling in 3 or 4 years. Foaling rates were low (4.1%) in mares bred as yearlings and rose with age to 70.8% in those bred as 4-year-olds. Fetal loss after Day 120 was deduced from faecal oestrogens to be 26.0% overall, with marked variation from year to year (9.6-37.3%) and with age (70.0% in those bred as yearlings, decreasing to 5.6% in those bred as 4-year-olds). Of 58 mares aged 2 years or older that were sampled every year, about half (49.6%) the barren years were attributable to fetal loss after 120 days gestation. All mares conceived in at least 2 of the 4 years, suggesting that pregnancy loss, even after Day 120, is as important as failure to conceive in causing barren years.
Address (down) Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph, Canada
Corporate Author Thesis
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Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0449-3087 ISBN Medium
Area Expedition Conference
Notes PMID:1795292 Approved no
Call Number Equine Behaviour @ team @ Serial 2247
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Author Dirikolu, L.; Lehner, A.F.; Karpiesiuk, W.; Hughes, C.; Woods, W.E.; Boyles, J.; Harkins, J.D.; Troppmann, A.; Tobin, T.
Title Detection, quantification, metabolism, and behavioral effects of selegiline in horses Type Journal Article
Year 2003 Publication Veterinary Therapeutics : Research in Applied Veterinary Medicine Abbreviated Journal Vet Ther
Volume 4 Issue 3 Pages 257-268
Keywords Administration, Oral; Animals; Behavior, Animal/drug effects; Female; Horses/*metabolism; Mass Spectrometry/veterinary; Monoamine Oxidase Inhibitors/administration & dosage/blood/*pharmacokinetics/pharmacology/urine; Selegiline/administration & dosage/blood/*pharmacokinetics/pharmacology/urine; Substance Abuse Detection/veterinary
Abstract Selegiline ([R]-[-]N,alpha-dimethyl-N-2- propynylphenethylamine or l-deprenyl), an irreversible inhibitor of monoamine oxidase, is a classic antidyskinetic and antiparkinsonian agent widely used in human medicine both as monotherapy and as an adjunct to levodopa therapy. Selegiline is classified by the Association of Racing Commissioners International (ARCI) as a class 2 agent, and is considered to have high abuse potential in racing horses. A highly sensitive LC/MS/MS quantitative analytical method has been developed for selegiline and its potential metabolites amphetamine and methamphetamine using commercially available deuterated analogs of these compounds as internal standards. After administering 40 mg of selegiline orally to two horses, relatively low (<60 ng/ml) concentrations of parent selegiline, amphetamine, and methamphetamine were recovered in urine samples. However, relatively high urinary concentrations of another selegiline metabolite were found, tentatively identified as N- desmethylselegiline. This metabolite was synthesized and found to be indistinguishable from the new metabolite recovered from horse urine, thereby confirming the chemical identity of the equine metabolite. Additionally, analysis of urine samples from four horses dosed with 50 mg of selegiline confirmed that N-desmethylselegiline is the major urinary metabolite of selegiline in horses. In related behavior studies, p.o. and i.v. administration of 30 mg of selegiline produced no significant changes in either locomotor activities or heart rates.
Address (down) Department of Biomedical Sciences, College of Veterinary Medicine, Nursing and Allied Health, Tuskegee University, Tuskegee, AL 36088, USA
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1528-3593 ISBN Medium
Area Expedition Conference
Notes PMID:15136987 Approved no
Call Number Serial 1901
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