| Records |
| Author |
Steinhoff, H.J.; Lieutenant, K.; Redhardt, A. |
| Title |
Conformational transition of aquomethemoglobin: intramolecular histidine E7 binding reaction to the heme iron in the temperature range between 220 K and 295 K as seen by EPR and temperature-jump measurements |
Type |
Journal Article |
| Year |
1989 |
Publication |
Biochimica et Biophysica Acta |
Abbreviated Journal |
Biochim Biophys Acta |
| Volume |
996 |
Issue |
1-2 |
Pages |
49-56 |
| Keywords |
Animals; Electron Spin Resonance Spectroscopy; Heme; Histidine; Horses; Humans; Hydrogen-Ion Concentration; Methemoglobin/*ultrastructure; Motion; Protein Conformation; Temperature; Thermodynamics; Water |
| Abstract |
Temperature-dependent EPR and temperature-jump measurements have been carried out, in order to examine the high-spin to low-spin transition of aquomethemogobin (pH 6.0). Relaxation rates and equilibrium constants could be determined as a function of temperature. As a reaction mechanism for the high-spin to low-spin transition, the binding of N epsilon of His E7 to the heme iron had been proposed; the same mechanism had been suggested for the ms-effect, found in temperature-jump experiments on aquomethemoglobin. A comparison of the thermodynamic quantities, deduced form the measurements in this paper, gives evidence that indeed the same reaction is investigated in both cases. Our results and most of the findings of earlier studies on the spin-state transitions of aquomethemoglobin, using susceptibility, optical, or EPR measurements, can be explained by the transition of methemoglobin with H2O as ligand (with high-spin state at all temperatures) and methemoglobin with ligand N epsilon of His E7 (with a low-spin ground state). Thermal fluctuations of large amplitude have to be postulated for the reaction to take place, so this reaction may be understood as a probe for the study of protein dynamics. |
Address  |
Institut fur Biophysik, Ruhr-Universitat Bochum, F.R.G |
| Corporate Author |
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Thesis |
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| Publisher |
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Place of Publication |
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Editor |
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| Language |
English |
Summary Language |
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Original Title |
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| Series Editor |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
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Edition |
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| ISSN |
0006-3002 |
ISBN |
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Medium |
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| Area |
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Expedition |
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Conference |
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| Notes |
PMID:2544230 |
Approved |
no |
| Call Number |
Equine Behaviour @ team @ |
Serial |
3803 |
| Permanent link to this record |
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| Author |
Lemasson, J.J.; Fontenille, D.; Lochouarn, L.; Dia, I.; Simard, F.; Ba, K.; Diop, A.; Diatta, M.; Molez, J.F. |
| Title |
Comparison of behavior and vector efficiency of Anopheles gambiae and An. arabiensis (Diptera:Culicidae) in Barkedji, a Sahelian area of Senegal |
Type |
Journal Article |
| Year |
1997 |
Publication |
Journal of Medical Entomology |
Abbreviated Journal |
J Med Entomol |
| Volume |
34 |
Issue |
4 |
Pages |
396-403 |
| Keywords |
Animals; Anopheles/*parasitology; *Behavior, Animal; Cattle; Desert Climate; Horses/parasitology; Humans; Insect Vectors/*parasitology; Longitudinal Studies; Malaria/*transmission; Malaria, Falciparum/transmission; Periodicity; Plasmodium malariae/isolation & purification; Protozoan Proteins/analysis; Rain; Seasons; Senegal; Sheep/parasitology; Species Specificity |
| Abstract |
The ecology, population dynamics, and malaria vector efficiency of Anopheles gambiae and An. arabiensis were studied for 2 yr in a Sahelian village of Senegal. Anophelines were captured at human bait and resting indoors by pyrethrum spray. Mosquitoes belonging to the An. gambiae complex were identified by polymerase chain reaction. Of 26,973 females, An. arabiensis represented 79% of the mosquitoes captured and remained in the study area longer than An. gambiae after the rains terminated. There were no differences in nocturnal biting cycles or endophagous rates between An. gambiae and An. arabiensis. Based on an enzyme-linked immunosorbent assay test of bloodmeals, the anthropophilic rate of these 2 vectors were both approximately 60%, when comparisons were made during the same period. Overall, 18% of the resting females had patent mixed bloodmeals, mainly human-bovine. The parity rates of An. gambiae and An. arabiensis varied temporally. Despite similar behavior, the Plasmodium falciparum circumsporozoite protein (CSP) rates were different between An. gambiae (4.1%) and An. arabiensis (1.3%). P. malariae and P. ovale only represented 4% of the total Plasmodium identified in mosquitoes. Transmission was seasonal, occurring mainly during 4 mo. The CSP entomological inoculation rates were 128 bites per human per year for the 1st yr and 100 for the 2nd yr. Because of the combination of a high human biting rate and a low CSP rate, An. arabiensis accounted for 63% of transmission. Possible origin of differences in CSP rate between An. gambiae and An. arabiensis is discussed in relation to the parity rate, blood feeding frequency, and the hypothesis of genetic factors. |
| Address |
Institut Francais de Recherche Scientifique pour le Developpement en cooperation (ORSTOM), Institut Pasteur, Dakar, Senegal |
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Thesis |
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Place of Publication |
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Editor |
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| Language |
English |
Summary Language |
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Original Title |
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| Series Editor |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
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Edition |
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| ISSN |
0022-2585 |
ISBN |
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Medium |
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| Area |
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Expedition |
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Conference |
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| Notes |
PMID:9220672 |
Approved |
no |
| Call Number |
Equine Behaviour @ team @ |
Serial |
2655 |
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| Author |
Rosa, P.A.J.; Azevedo, A.M.; Aires-Barros, M.R. |
| Title |
Application of central composite design to the optimisation of aqueous two-phase extraction of human antibodies |
Type |
Journal Article |
| Year |
2007 |
Publication |
Journal of Chromatography. A |
Abbreviated Journal |
J Chromatogr A |
| Volume |
1141 |
Issue |
1 |
Pages |
50-60 |
| Keywords |
Analysis of Variance; Animals; Antibodies/*chemistry/*isolation & purification; Buffers; Chemical Fractionation/*methods; Horses; Humans; Hydrophobicity; Isoelectric Point; Models, Biological; Molecular Weight; Myoglobin/chemistry/isolation & purification; Osmolar Concentration; Phase Transition; Polyethylene Glycols; Serum Albumin/chemistry/isolation & purification; Sodium Chloride |
| Abstract |
The partition of human antibodies in aqueous two-phase systems (ATPSs) of polyethylene glycol (PEG) and phosphate was systematically studied using first pure proteins systems and then an artificial mixture of proteins containing 1mg/ml human immunoglobulin G (IgG), 10mg/ml serum albumin and 2mg/ml myoglobin. Preliminary results obtained using pure proteins systems indicated that the PEG molecular weight and concentration, the pH value and the salts concentration had a pronounced effect on the partitioning behaviour of all proteins. For high ionic strengths and pH values higher than the isoelectric point (pI) of the contaminant proteins, IgG could be selectively recovered on the top phase. According to these results, a face centred composite design was performed in order to optimise the purification of IgG from the mixture of proteins. The optimal conditions for the isolation of IgG were observed for high concentrations of NaCl and low concentrations of both phase forming components. The best purification was achieved using an ATPS containing 8% (w/w) PEG 3350, 10% (w/w) phosphate pH 6 and 15% (w/w) NaCl. A recovery yield of 101+/-7%, a purity of 99+/-0% and a yield of native IgG of 97+/-4% were obtained. Back extraction studies of IgG to a new phosphate phase were performed and higher yields were obtained using 10% phosphate buffer at pH 6. The total extraction yield was 76% and the purity 100%. |
| Address |
IBB Institute for Biotechnology and Bioengineering, Centre for Biological and Chemical Engineering, Instituto Superior Tecnico, Av Rovisco Pais, 1049-001 Lisbon, Portugal |
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Thesis |
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Place of Publication |
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Editor |
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| Language |
English |
Summary Language |
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Original Title |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
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Edition |
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| ISSN |
0021-9673 |
ISBN |
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Medium |
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| Area |
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Expedition |
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Conference |
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| Notes |
PMID:17196214 |
Approved |
no |
| Call Number |
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Serial |
1842 |
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| Author |
Kaiser, L.; Heleski, C.R.; Siegford, J.; Smith, K.A. |
| Title |
Stress-related behaviors among horses used in a therapeutic riding program |
Type |
Journal Article |
| Year |
2006 |
Publication |
Journal of the American Veterinary Medical Association |
Abbreviated Journal |
J Am Vet Med Assoc |
| Volume |
228 |
Issue |
1 |
Pages |
39-45 |
| Keywords |
Adult; Animals; Behavior, Animal/*physiology; Child; *Disabled Persons; Female; Horses/*psychology; Humans; Male; *Mentally Disabled Persons; Occupational Therapy/methods; Recreation; Risk Factors; Stress/*veterinary |
| Abstract |
OBJECTIVE: To determine whether therapeutic riding resulted in higher levels of stress or frustration for horses than did recreational riding and whether therapeutic riding with at-risk individuals was more stressful for the horses than was therapeutic riding with individuals with physical or emotional handicaps. DESIGN: Observational study. ANIMALS: 14 horses in a therapeutic riding program. PROCEDURE: An ethogram of equine behaviors was created, and horses were observed while ridden by 5 groups of riders (recreational riders, physically handicapped riders, psychologically handicapped riders, at risk children, and special education children). Number of stress-related behaviors (ears pinned back, head raised, head turned, head tossed, head shaken, head down, and defecation) was compared among groups. RESULTS: No significant differences in mean number of stress-related behaviors were found when horses were ridden by recreational riders, physically handicapped riders, psychologically handicapped riders, or special education children. However, mean number of stress-related behaviors was significantly higher when horses were ridden by the at-risk children. CONCLUSIONS AND CLINICAL RELEVANCE: Results suggest that for horses in a therapeutic riding program, being ridden by physically or psychologically handicapped individuals is no more stressful for the horses than is being ridden in the same setting by recreational riders. However, at-risk children caused more stress to the horses, suggesting that the time horses are ridden by at-risk children should be limited both daily and weekly. |
| Address |
Human-Animal Bond Initiative, College of Nursing, Michigan State University, East Lansing, MI 48824, USA |
| Corporate Author |
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Thesis |
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| Publisher |
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Place of Publication |
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Editor |
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| Language |
English |
Summary Language |
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Original Title |
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| Series Editor |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
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Edition |
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| ISSN |
0003-1488 |
ISBN |
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Medium |
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| Area |
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Expedition |
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Conference |
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| Notes |
PMID:16426164 |
Approved |
no |
| Call Number |
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Serial |
1879 |
| Permanent link to this record |
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| Author |
Kaiser, L.; Smith, K.A.; Heleski, C.R.; Spence, L.J. |
| Title |
Effects of a therapeutic riding program on at-risk and special education children |
Type |
Journal Article |
| Year |
2006 |
Publication |
Journal of the American Veterinary Medical Association |
Abbreviated Journal |
J Am Vet Med Assoc |
| Volume |
228 |
Issue |
1 |
Pages |
46-52 |
| Keywords |
Adolescent; Anger; Animals; *Bonding, Human-Pet; Child; Child Behavior; *Child Psychology; Disabled Persons/*psychology/rehabilitation; Female; Horses; Humans; Mainstreaming (Education); Male; Mothers/*psychology; Occupational Therapy/*methods; Recreation; Self Efficacy; Sports/*psychology |
| Abstract |
OBJECTIVE: To determine the effects of a therapeutic riding program on psychosocial measurements among children considered at risk for poor performance or failure in school or life and among children in special education programs. DESIGN: Observational study. POPULATION: 17 at-risk children (6 boys and 11 girls) and 14 special education children (7 boys and 7 girls). PROCEDURE: For the at-risk children, anger, anxiety, perceived self-competence, and physical coordination were assessed. For the special education children, anger and cheerfulness were measured, and the children's and their mothers' perceptions of the children's behavior were assessed. Measurements were made before and after an 8-session therapeutic riding program. RESULTS: For boys enrolled in the special education program, anger was significantly decreased after completion of the riding program. The boys' mothers also perceived significant improvements in their children's behavior after completion of the program. CONCLUSIONS AND CLINICAL RELEVANCE: Results suggest that an 8-session therapeutic riding program can significantly decrease anger in adolescent boys in a special education program and positively affect their mothers' perception of the boys' behavior. |
| Address |
Human-Animal Bond Initiative, College of Nursing, Michigan State University, East Lansing, MI 48824, USA |
| Corporate Author |
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Thesis |
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| Publisher |
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Place of Publication |
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Editor |
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| Language |
English |
Summary Language |
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Original Title |
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| Series Editor |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
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Edition |
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| ISSN |
0003-1488 |
ISBN |
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Medium |
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| Area |
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Expedition |
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Conference |
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| Notes |
PMID:16426165 |
Approved |
no |
| Call Number |
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Serial |
1880 |
| Permanent link to this record |
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| Author |
Peltzer, K.; Mabilu, M.G.; Mathoho, S.F.; Nekhwevha, A.P.; Sikhwivhilu, T.; Sinthumule, T.S. |
| Title |
Trauma history and severity of gambling involvement among horse-race gamblers in a South African gambling setting |
Type |
Journal Article |
| Year |
2006 |
Publication |
Psychological Reports |
Abbreviated Journal |
Psychol Rep |
| Volume |
99 |
Issue |
2 |
Pages |
472-476 |
| Keywords |
Adult; African Continental Ancestry Group/*psychology/statistics & numerical data; Aged; Aged, 80 and over; Cross-Sectional Studies; Female; Gambling/*psychology; Humans; *Life Change Events; Male; Middle Aged; Personality Inventory; Risk Factors; *Social Environment; Socioeconomic Factors; South Africa; Statistics; Stress Disorders, Post-Traumatic/epidemiology/*psychology |
| Abstract |
The purpose of this study was to ascertain the frequency of gambling involvement and the prevalence of problem gambling among horse race gamblers and to discover whether problem gambling in this sample is associated with a history of trauma. Among a sample of 266 South African horse-race gamblers (94% men and 6% women, Mage 46.8 yr., SD = 13.9, range 18-85 years), 31.2% were classified as probable pathological gamblers and 19.9% with problem gambling. Major weekly gambling activities included racetrack betting (82%), purchase of lottery tickets or scratch tickets (35%), purchase of sports lottery tickets (23%), and using casino type games (18%). Trauma history was significantly associated with gambling severity. |
| Address |
Human Sciences Research Council, University of Limpopo, Pretoria, South Africa. KPeltzer@hsrc.ac.za |
| Corporate Author |
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Thesis |
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| Publisher |
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Place of Publication |
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Editor |
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| Language |
English |
Summary Language |
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Original Title |
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| Series Editor |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
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Edition |
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| ISSN |
0033-2941 |
ISBN |
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Medium |
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| Area |
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Expedition |
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Conference |
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| Notes |
PMID:17153816 |
Approved |
no |
| Call Number |
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Serial |
1850 |
| Permanent link to this record |
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| Author |
Romano, N.; Vitale, F.; Alesi, D.R.; Bonura, F.; La Licata, R.; Intonazzo, V.; Dardanoni, G.; Mammina, C. |
| Title |
The changing pattern of human immunodeficiency virus type 1 infection in intravenous drug users. Results of a six-year seroprevalence study in Palermo, Italy |
Type |
Journal Article |
| Year |
1992 |
Publication |
American Journal of Epidemiology |
Abbreviated Journal |
Am J Epidemiol |
| Volume |
135 |
Issue |
11 |
Pages |
1189-1196 |
| Keywords |
Acquired Immunodeficiency Syndrome/*epidemiology; Adolescent; Adult; Chi-Square Distribution; Cross-Sectional Studies; Female; HIV Antibodies/blood; HIV Infections/*epidemiology; HIV Seroprevalence/*trends; *Hiv-1; Hepatitis B Antibodies/blood; Hepatitis B Surface Antigens/blood; Heroin; Humans; Incidence; Italy/epidemiology; Logistic Models; Male; Multivariate Analysis; Odds Ratio; Prevalence; Risk Factors; Substance Abuse, Intravenous/*epidemiology; Time Factors |
| Abstract |
A cross-sectional seroepidemiologic study was carried out between 1985 and 1990 in 1,567 heterosexual intravenous drug users who had been seen at the AIDS Regional Reference Center in Palermo, Italy, to evaluate the rate of human immunodeficiency virus type 1 (HIV-1) seroprevalence in this group and its long-term trend. Sixty serum samples collected from drug users in 1980 and 1983, before the founding of the Center (1985), were tested as well. Some demographic and behavioral risk factors were studied in a subgroup of intravenous drug users enrolled in 1985, 1987, and 1990 for their possible association with HIV-1. These factors were also studied in relation to hepatitis B virus infection, since both viruses share the same modes of spread. These drug users had a higher prevalence of markers for hepatitis B virus than of HIV-1 antibodies, and the prevalence rates in sera collected declined over time for both infections. The presence of both antibodies to HIV-1 and markers for hepatitis B virus was independently associated with the age of the drug user, the duration of drug use, and the year of serum collection. Antibodies to HIV-1 were observed more frequently in females than in males. No relation was found between education or employment status and the presence of HIV-1 antibodies or hepatitis B virus markers. Although new HIV-1 infections still occur, the decline in seroprevalence observed at the end of the 1980s might be related to modifications in social behavior among newer drug users, partial exhaustion of the susceptible population, and increasing risk awareness in more experienced users. |
| Address |
Giuseppe D'Alessandro Department of Hygiene and Microbiology, School of Medicine, University of Palermo, Italy |
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Thesis |
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Place of Publication |
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Editor |
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| Language |
English |
Summary Language |
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Original Title |
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| Series Editor |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
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Edition |
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| ISSN |
0002-9262 |
ISBN |
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Medium |
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| Area |
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Expedition |
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Conference |
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| Notes |
PMID:1626537 |
Approved |
no |
| Call Number |
Equine Behaviour @ team @ |
Serial |
5258 |
| Permanent link to this record |
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| Author |
Morley, K.I.; Montgomery, G.W. |
| Title |
The genetics of cognitive processes: candidate genes in humans and animals |
Type |
Journal Article |
| Year |
2001 |
Publication |
Behavior Genetics |
Abbreviated Journal |
Behav Genet |
| Volume |
31 |
Issue |
6 |
Pages |
511-531 |
| Keywords |
Animals; *Chromosome Mapping; Drosophila melanogaster; Genetic Markers/*genetics; Humans; Intelligence/*genetics; Mental Retardation/genetics; Mice; Phenotype; Quantitative Trait, Heritable |
| Abstract |
It has been hypothesized that numerous genes contribute to individual variation in human cognition. An extensive search of the scientific literature was undertaken to identify candidate genes which might contribute to this complex trait. A list of over 150 candidate genes that may influence some aspect of cognition was compiled. Some genes are particularly strong candidates based on evidence for involvement in cognitive processes in humans, mice, and Drosophila melanogaster. This survey confirms that many genes are associated with cognitive variation and highlights the potential importance of animal models in the study of human cognition. |
| Address |
Genetic Epidemiology Laboratory, Queensland Institute of Medical Research, Brisbane, Australia |
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Thesis |
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Place of Publication |
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Editor |
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| Language |
English |
Summary Language |
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Original Title |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
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Edition |
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| ISSN |
0001-8244 |
ISBN |
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Medium |
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| Area |
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Expedition |
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Conference |
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| Notes |
PMID:11838530 |
Approved |
no |
| Call Number |
Equine Behaviour @ team @ |
Serial |
4141 |
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| Author |
Pollmann, U. |
| Title |
[Keeping of horses in circus and show businesses] |
Type |
Journal Article |
| Year |
2002 |
Publication |
DTW. Deutsche Tierarztliche Wochenschrift |
Abbreviated Journal |
Dtsch Tierarztl Wochenschr |
| Volume |
109 |
Issue |
3 |
Pages |
126-129 |
| Keywords |
Animal Husbandry/*methods; *Animal Welfare; Animals; Behavior, Animal; *Horses; *Housing, Animal; Humans; Reward |
| Abstract |
The conditions under which horses are kept and the performance of acts in the circus ring may give rise to animal protection-relevant aspects for circus and show horses. A number of intolerable conditions under which horses are kept and procedures adopted for the work with circus and show horses are described. In addition, attention is drawn to monitoring methods capable of exposing the deplorable shortcomings of these businesses. |
| Address |
Fachbereich Ethologie und Tierschutz des Chemischen und Veterinaruntersuchungsamtes Freiburg. Ursula.Pollmann@cvuafr.bwl.de |
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Thesis |
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| Publisher |
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Place of Publication |
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Editor |
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| Language |
German |
Summary Language |
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Original Title |
Pferdehaltung in Zirkus- und Schaustellerbetrieben |
| Series Editor |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
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Edition |
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| ISSN |
0341-6593 |
ISBN |
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Medium |
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| Area |
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Expedition |
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Conference |
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| Notes |
PMID:11963363 |
Approved |
no |
| Call Number |
refbase @ user @ |
Serial |
1914 |
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| Author |
Dunbar, R.I.M.; McAdam, M.R.; O'connell, S. |
| Title |
Mental rehearsal in great apes (Pan troglodytes and Pongo pygmaeus) and children |
Type |
Journal Article |
| Year |
2005 |
Publication |
Behavioural Processes |
Abbreviated Journal |
Behav. Process. |
| Volume |
69 |
Issue |
3 |
Pages |
323-330 |
| Keywords |
Algorithms; Animals; Child; Child, Preschool; Food; Frontal Lobe/anatomy & histology/physiology; Humans; *Imagination; Pan troglodytes; Pongo pygmaeus; Problem Solving/*physiology; Psychomotor Performance/physiology; Reward |
| Abstract |
The ability to rehearse possible future courses of action in the mind is an important feature of advanced social cognition in humans, and the “social brain” hypothesis implies that it might also be a feature of primate social cognition. We tested two chimpanzees, six orangutans and 63 children aged 3-7 years on a set of four puzzle boxes, half of which were presented with an opportunity to observe the box before being allowed to open it (“prior view”), the others being given without an opportunity to examine the boxes before handling them (“no prior view”). When learning effects are partialled out, puzzle boxes in the “prior view” condition were opened significantly faster than boxes given in the “no prior view” condition by the children, but not by either of the great apes. The three species differ significantly in the speed with which they opened boxes in the “no prior view” condition. The three species' performance on this task was a function of relative frontal lobe volume, suggesting that it may be possible to identify quantitative neuropsychological differences between species. |
| Address |
Evolutionary Psychology Research Group, School of Biological Sciences, University of Liverpool, Biosciences Building, Crown Street, Liverpool L69 7ZB, UK. rimd@liv.ac.uk |
| Corporate Author |
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Thesis |
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| Publisher |
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Place of Publication |
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Editor |
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| Language |
English |
Summary Language |
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Original Title |
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| Series Editor |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
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Edition |
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| ISSN |
0376-6357 |
ISBN |
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Medium |
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| Area |
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Expedition |
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Conference |
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| Notes |
PMID:15896530 |
Approved |
no |
| Call Number |
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Serial |
2097 |
| Permanent link to this record |
