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Author Verheyen, K.; Price, J.; Lanyon, L.; Wood, J. doi  openurl
  Title Exercise distance and speed affect the risk of fracture in racehorses Type Journal Article
  Year 2006 Publication Bone Abbreviated Journal Bone  
  Volume 39 Issue 6 Pages 1322-1330  
  Keywords Animals; Case-Control Studies; Cohort Studies; England; Exertion; Female; Fractures, Bone/etiology/*veterinary; Horse Diseases/*etiology; Horses/*injuries; Male; Physical Conditioning, Animal/adverse effects/methods; Poisson Distribution; Prospective Studies; Regression Analysis; Risk Factors; Running/injuries/physiology  
  Abstract (up) In order to gain insight into those training regimens that can minimise the risk of fracture in athletic populations, we conducted a large epidemiological study in racehorses. Thoroughbred racehorses provide a suitable model for studying fracture development and exercise-related risk factors in physically active populations. They represent a homogeneous population, undertaking intensive exercise programmes that are sufficiently heterogeneous to determine those factors that influence injury risk. Daily exercise information was recorded for a cohort of 1178 thoroughbreds that were monitored for up to 2 years. A total of 148 exercise-induced fractures occurred in the study population. Results from a nested case-control study showed a strong interactive effect of exercise distances at different speeds on fracture risk. Horses that exceeded 44 km at canter (< or =14 m/s) and 6 km at gallop (>14 m/s) in a 30-day period were at particularly increased risk of fracture. These distances equate to ca. 7700 bone loading cycles at canter and 880 loading cycles at gallop. Fifty-six fractures occurred in the subset of study horses that were followed since entering training as yearlings, when skeletally immature (n = 335). Cohort analysis of this data set showed that, in previously untrained bones, accumulation of canter exercise increased the risk of fracture (P < or = 0.01), whereas accumulation of high-speed gallop exercise had a protective effect (P < 0.01). However, increasing distances at canter and gallop in short time periods (up to one month) were associated with an increasing fracture risk. All training exercise involves a balance between the risk of fracture inherent in exposure to loading and the beneficial effect that loading has by stimulating bone cells to produce a more robust architecture. Results from our study provide important epidemiological evidence of the effects of physical exercise on bone adaptation and injury risk and can be used to inform the design of safer exercise regimens in physically active populations.  
  Address Epidemiology Unit, Animal Health Trust, Newmarket, United Kingdom. kverheyen@rvc.ac.uk  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 8756-3282 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:16926125 Approved no  
  Call Number Equine Behaviour @ team @ Serial 4030  
Permanent link to this record
 

 
Author Faber, M.J.; van Weeren, P.R.; Schepers, M.; Barneveld, A. openurl 
  Title Long-term follow-up of manipulative treatment in a horse with back problems Type Journal Article
  Year 2003 Publication Journal of Veterinary Medicine. A, Physiology, Pathology, Clinical Medicine Abbreviated Journal J Vet Med A Physiol Pathol Clin Med  
  Volume 50 Issue 5 Pages 241-245  
  Keywords Animals; Female; Horse Diseases/*physiopathology/*therapy; Horses; Manipulation, Spinal/*veterinary; Range of Motion, Articular; Scoliosis/physiopathology/therapy/*veterinary; Severity of Illness Index; Thoracic Vertebrae  
  Abstract (up) In order to objectively quantify the effect of manipulation on back-related locomotion anomalies in the horse, a recently developed kinematic measuring technique for the objective quantification of thoracolumbar motion in the horse was applied in a dressage horse that was suffering from a back problem. In this horse, clinically, a right-convex bending (scoliosis) from the 10th thoracic vertebra to the second lumbar vertebra was diagnosed. As a result, there was a marked asymmetric movement of the thoracolumbar spine. Functionally, there was severe loss of performance. Thoracolumbar motion was measured in terms of ventrodorsal flexion, lateral flexion, and axial rotation using an automated gait analysis system. Measurements were repeated before and 2 days after treatment, before the second treatment 3 weeks later, and at 4 weeks and 8 months after the second treatment to assess long-term effect. At the same time, performance of the horse was assessed subjectively by the trainer as well. Symmetry of movement improved dramatically after the first treatment. After this, there was a slight decrease in symmetry, but 8 months after the last treatment the symmetry indexes for the various joints were still considerably better than during the first (pre-treatment) measuring session. Subjectively, the trainer did not notice improvement until after measurement session 4. Between sessions 4 and 5 (at 4 weeks and 8 months after the second treatment) there was a change of trainer. The new trainer did not report any back problem, and succeeded in bringing the horse back to its former level in competition. It is concluded that manipulation had a measurable influence on the kinematics of the thoracolumbar spine. However, it is recognized that an improvement in symmetry of motion is not equivalent to clinical improvement and that other measures, such as changes in management, may be more decisive.  
  Address Department of Equine Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0931-184X ISBN Medium  
  Area Expedition Conference  
  Notes PMID:14567510 Approved no  
  Call Number Equine Behaviour @ team @ Serial 3720  
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Author Milinovich, G.J.; Trott, D.J.; Burrell, P.C.; van Eps, A.W.; Thoefner, M.B.; Blackall, L.L.; Al Jassim, R.A.M.; Morton, J.M.; Pollitt, C.C. doi  openurl
  Title Changes in equine hindgut bacterial populations during oligofructose-induced laminitis Type Journal Article
  Year 2006 Publication Environmental Microbiology Abbreviated Journal Environ Microbiol  
  Volume 8 Issue 5 Pages 885-898  
  Keywords Animal Feed; Animals; Bacteria/classification/*isolation & purification; DNA, Bacterial/analysis; Disease Models, Animal; Feces/microbiology; Foot Diseases/etiology/microbiology/*veterinary; Horse Diseases/*etiology/metabolism/microbiology; Horses; In Situ Hybridization, Fluorescence; Intestines/*microbiology; Oligosaccharides/*administration & dosage/*metabolism; Phylogeny; Polymerase Chain Reaction; RNA, Bacterial/analysis; RNA, Ribosomal, 16S/analysis  
  Abstract (up) In the horse, carbohydrate overload is thought to play an integral role in the onset of laminitis by drastically altering the profile of bacterial populations in the hindgut. The objectives of this study were to develop and validate microbial ecology methods to monitor changes in bacterial populations throughout the course of experimentally induced laminitis and to identify the predominant oligofructose-utilizing organisms. Laminitis was induced in five horses by administration of oligofructose. Faecal specimens were collected at 8 h intervals from 72 h before to 72 h after the administration of oligofructose. Hindgut microbiota able to utilize oligofructose were enumerated throughout the course of the experiment using habitat-simulating medium. Isolates were collected and representatives identified by 16S rRNA gene sequencing. The majority of these isolates collected belonged to the genus Streptococcus, 91% of which were identified as being most closely related to Streptococcus infantarius ssp. coli. Furthermore, S. infantarius ssp. coli was the predominant oligofructose-utilizing organism isolated before the onset of lameness. Fluorescence in situ hybridization probes developed to specifically target the isolated Streptococcus spp. demonstrated marked population increases between 8 and 16 h post oligofructose administration. This was followed by a rapid population decline which corresponded with a sharp decline in faecal pH and subsequently lameness at 24-32 h post oligofructose administration. This research suggests that streptococci within the Streptococcus bovis/equinus complex may be involved in the series of events which precede the onset of laminitis in the horse.  
  Address Australian Equine Laminitis Research Unit, School of Veterinary Science, The University of Queensland, Queensland, Australia. g.milinovich@uq.edu.au  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1462-2912 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:16623745 Approved no  
  Call Number Equine Behaviour @ team @ Serial 2625  
Permanent link to this record
 

 
Author Dowdle, W.R.; Schild, G.C. openurl 
  Title Influenza: its antigenic variation and ecology Type Journal Article
  Year 1976 Publication Bulletin of the Pan American Health Organization Abbreviated Journal Bull Pan Am Health Organ  
  Volume 10 Issue 3 Pages 193-195  
  Keywords Animals; *Antigens, Viral; Bird Diseases/microbiology; Birds; Hemagglutinins, Viral; Horse Diseases/microbiology; Horses; Humans; Influenza A virus/immunology/isolation & purification; Influenza, Human/epidemiology; Mutation; Neuraminidase/immunology; Orthomyxoviridae/enzymology/*immunology; Orthomyxoviridae Infections/microbiology/veterinary; Recombination, Genetic; Swine; Swine Diseases/microbiology  
  Abstract (up) Influenza viruses have two surface antigens, the glycoprotein structures hemagglutinin (HA) and neuraminidase (NA). Antibodies to each of these are associated with immunity, but the structures themselves are antigenically variable. When an antigenic change is gradual over time it is referred to as a drift, while a sudden complete or major change in either or both antigens is termed a shift. The mechanism of antigenic drift is usually attributed to selection of preexisting mutants by pressure from increasing immunity in the human population. The mechanism of antigenic shift is less clear, but one tentative hypothesis is that shifts arise from mammalian or avian reservoirs, or through genetic recombination of human and animal influenza strains.  
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0085-4638 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:187273 Approved no  
  Call Number Equine Behaviour @ team @ Serial 2700  
Permanent link to this record
 

 
Author Forbes, A.B. openurl 
  Title A review of regional and temporal use of avermectins in cattle and horses worldwide Type Journal Article
  Year 1993 Publication Veterinary Parasitology Abbreviated Journal Vet Parasitol  
  Volume 48 Issue 1-4 Pages 19-28  
  Keywords Animals; Anthelmintics/therapeutic use; Arthropods; Cattle; Cattle Diseases/drug therapy/*prevention & control; Ectoparasitic Infestations/drug therapy/prevention & control/veterinary; Horse Diseases/drug therapy/*prevention & control; Horses; Insecticides; Ivermectin/*analogs & derivatives/*therapeutic use; Nematode Infections/drug therapy/prevention & control/veterinary; Parasitic Diseases/drug therapy/prevention & control; *Parasitic Diseases, Animal  
  Abstract (up) Ivermectin and abamectin are two members of the group of parasiticides known as the avermectins; ivermectin was first registered as an injectable treatment for cattle in 1981. Since then, abamectin has been registered for cattle and ivermectin for horses. The relative popularity of the avermectins amongst farmers and veterinarians can be attributed to their spectrum of activity, convenience, wide margin of safety and the improved health and performance of stock following their use. Patterns of use in grazing animals apply equally to the avermectins as to other antiparasitics, particularly anthelmintics; these are based on a knowledge of epidemiology integrated with practical management considerations. For cattle, programs are commonly aimed at control of abomasal nematodes of the genera Ostertagia and Haemonchus. Use of avermectins is largely strategic in cattle, treatments being favored at the end of the period of transmission of these parasites; this frequently coincides with housing, entry into a feedlot or movement to another pasture. Simultaneous control of important ectoparasites at this time is an added benefit. Prophylactic use of avermectins at pasture is primarily targeted at the young first season grazing animal. In horses, a bimonthly treatment schedule during the period of risk has proved effective in helping prevent adverse effects of the main target parasites, including large and small strongyles and stomach bots. These patterns of use can be applied to the evaluation of the potential for avermectin residues in feces to have impact on pasture ecology. The evidence presented suggests that any effects are temporally and spatially limited. After more than a decade of practical use, there is no indication that avermectins have had a significant impact on pasture ecology and the environment.  
  Address MERCK AgVet, Rahway, NJ 07065-0912  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0304-4017 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:8346632 Approved no  
  Call Number Equine Behaviour @ team @ Serial 2665  
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Author Nelson, D.M.; Gardner, I.A.; Chiles, R.F.; Balasuriya, U.B.; Eldridge, B.F.; Scott, T.W.; Reisen, W.K.; James Maclachlan, N. doi  openurl
  Title Prevalence of antibodies against Saint Louis encephalitis and Jamestown Canyon viruses in California horses Type Journal Article
  Year 2004 Publication Comparative Immunology, Microbiology and Infectious Diseases Abbreviated Journal Comp Immunol Microbiol Infect Dis  
  Volume 27 Issue 3 Pages 209-215  
  Keywords Animals; Antibodies, Viral/*blood; California/epidemiology; Encephalitis Virus, California/*immunology/isolation & purification; Encephalitis Virus, St. Louis/*immunology/isolation & purification; Encephalitis, St. Louis/epidemiology/immunology/*veterinary/virology; Female; Horse Diseases/epidemiology/immunology/*virology; Horses; Logistic Models; Male; Neutralization Tests/veterinary; Polyomavirus Infections/epidemiology/immunology/*veterinary/virology; Questionnaires; Seroepidemiologic Studies; Tumor Virus Infections/epidemiology/immunology/*veterinary/virology  
  Abstract (up) Jamestown Canyon (JC) and Saint Louis encephalitis (SLE) viruses are mosquito-transmitted viruses that have long been present in California. The objective of this study was to determine the seroprevalence of these two viruses in horses prior to the introduction of West Nile (WN) virus. Approximately 15% of serum samples collected in 1998 from 425 horses on 44 equine operations horses throughout California had serum antibodies to JC virus, whereas antibodies were not detected to SLE virus. The results indicate that horses in California were commonly infected prior to 1998 with mosquito-transmitted Bunyaviruses that are identical or closely related to JC virus, but not with SLE virus. The different seroprevalence of SLE and JC viruses in horses likely reflects the unique ecology of each virus, and it is predicted that WN virus will have a wider distribution in California than closely related SLE virus.  
  Address Animal and Plant Health Inspection Service, Veterinary Services, U.S. Department of Agriculture, California and Nevada Area Office, 9850 Micron Avenue, Suite E, Sacramento, CA 95827, USA  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0147-9571 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:15001316 Approved no  
  Call Number Equine Behaviour @ team @ Serial 2637  
Permanent link to this record
 

 
Author Hertsch, B. openurl 
  Title [The appearance of stress on the movement apparatus in dressage, jumping and versatility horses] Type Journal Article
  Year 1992 Publication DTW. Deutsche Tierarztliche Wochenschrift Abbreviated Journal Dtsch Tierarztl Wochenschr  
  Volume 99 Issue 1 Pages 36-39  
  Keywords Animals; Bone Diseases/etiology/*veterinary; Horse Diseases/*etiology; Horses/*injuries; Joint Diseases/etiology/*veterinary; *Sports; Stress, Mechanical; Tendon Injuries/etiology/veterinary  
  Abstract (up) Jumping and military (three days events) horses are exposed, during sports activities, to a particularly high stress especially in the region of the extremities (limbs). The genesis of tendon, joint and bone diseases are traced in accordance to the centers of the load during movement sequence. A special statistics on injuries concerning the German competition horses does not exist yet. Out of the available statistics about the German competition horses it is not obvious that as a result of its use as sports horses a particular high loss occur among these horses.  
  Address Klinik fur Pferde, Tierarztlichen Hoschschule Hannover  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language German Summary Language Original Title Belastungserscheinungen am Bewegungsapparat bei Dressur-, Spring- und Vielseitigkeitspferden  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0341-6593 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:1555516 Approved no  
  Call Number Equine Behaviour @ team @ Serial 3755  
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Author Barwick, R.S.; Mohammed, H.O.; McDonough, P.L.; White, M.E. openurl 
  Title Epidemiologic features of equine Leptospira interrogans of human significance Type Journal Article
  Year 1998 Publication Preventive Veterinary Medicine Abbreviated Journal Prev Vet Med  
  Volume 36 Issue 2 Pages 153-165  
  Keywords Animals; Horse Diseases/epidemiology/*microbiology; Horses/microbiology; Humans; *Leptospira interrogans; New York/epidemiology; Weil Disease/epidemiology/microbiology/*veterinary; Zoonoses/epidemiology/*microbiology  
  Abstract (up) Leptospirosis is a zoonotic bacterial disease caused by Leptospira interrogans. There is a serologic evidence that horses are exposed to L. interrogans and, as a shedder of these organisms, can be a threat to humans. We examined risk factors associated with the risk of testing seropositive to three L. interrogans serovars (L. icterohaemorrhagiae, L. grippotyphosa, and L. canicola) in the horses of New York State, in order to understand the epidemiology of the disease and suggest strategies to control and prevent equine leptospirosis. To carry out this study, blood samples were collected from a random sample of 2551 horses and tested for the presence of antibodies to the above serovars using the microscopic agglutination test. Samples with a titer $100 were considered positive. Clinical and demographic data were collected on each horse, the farms' management practices and ecology. Logistic regression analysis was used to develop a multivariate indexing system and to identify factors significantly associated with the risk of leptospirosis. Four indices were developed based on the possible sources of exposure: rodent exposure index; wildlife exposure index; soil and water index; and management index. The soil and water index was significantly associated with the risk of exposure to all three serovars. Management was positively associated with L. icterohaemorrhagiae and L. canicola. Density of horses turned out together was positively associated with the risk of exposure to L. grippotyphosa. We concluded that indirect exposure of horses to L. interrogans through contaminated soil and water appears to be significantly associated with the risk of exposure to all three serovars. Management appears to play an important role in the exposure to L. interrogans. Modification of management practices might reduce the horses' risk of exposure and hopefully minimize the human hazards.  
  Address Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0167-5877 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:9762736 Approved no  
  Call Number Equine Behaviour @ team @ Serial 2653  
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Author Nicol, C.J.; Davidson, H.P.D.; Harris, P.A.; Waters, A.J.; Wilson, A.D. openurl 
  Title Study of crib-biting and gastric inflammation and ulceration in young horses Type Journal Article
  Year 2002 Publication The Veterinary record Abbreviated Journal Vet. Rec.  
  Volume 151 Issue 22 Pages 658-662  
  Keywords Animal Husbandry/methods; Animals; Antacids/therapeutic use; *Behavior, Animal; Diet/veterinary; Endoscopy, Gastrointestinal/veterinary; Feces/chemistry; Female; Gastritis/diet therapy/physiopathology/*veterinary; Horse Diseases/diet therapy/*physiopathology/psychology; Horses; Hydrogen-Ion Concentration; Male; Random Allocation; Stereotyped Behavior/*physiology; Stomach Ulcer/diet therapy/physiopathology/*veterinary; Treatment Outcome; Weaning  
  Abstract (up) Nineteen young horses that had recently started to perform the stereotypy of crib-biting were compared with 16 non-stereotypic horses for 14 weeks. After initial observations of their behaviour and an endoscopic examination of the condition of their stomachs, the horses were randomly allocated to a control or an antacid diet At the start of the trial, the stomachs of the crib-biting foals were significantly more ulcerated and inflamed than the stomachs of the normal foals. In addition, the faecal pH of the crib-biting foals (6.05) was significantly lower than that of the normal foals (6.58). The antacid diet resulted in a significant improvement in the condition of the horses' stomachs. The crib-biting behaviour declined in most of the foals, regardless of their diet, but tended to decline to a greater extent in the foals on the antacid diet.  
  Address Department of Clinical Veterinary Science, University of Bristol, Langford House, Bristol BS40 5DU  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0042-4900 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:12498408 Approved no  
  Call Number refbase @ user @ Serial 83  
Permanent link to this record
 

 
Author Dargatz, D.A.; Traub-Dargatz, J.L. doi  openurl
  Title Multidrug-resistant Salmonella and nosocomial infections Type Journal Article
  Year 2004 Publication The Veterinary Clinics of North America. Equine Practice Abbreviated Journal Vet Clin North Am Equine Pract  
  Volume 20 Issue 3 Pages 587-600  
  Keywords Animals; Anti-Bacterial Agents/*pharmacology; Cross Infection/prevention & control/*veterinary; Disease Outbreaks/prevention & control/veterinary; Drug Resistance, Bacterial; *Drug Resistance, Multiple, Bacterial; Horse Diseases/*drug therapy/transmission; Horses; Infection Control/methods; Microbial Sensitivity Tests/veterinary; Salmonella/*drug effects; Salmonella Infections, Animal/*drug therapy/transmission  
  Abstract (up) Nosocomial infections are a serious threat to optimum patient care. In addition, nosocomial infections can have far-reaching consequences for the hospital personnel and the financial aspects of the hospital. Nosocomial infections with Salmonella spp have been described among hospitalized equine populations more frequently than any other agent. Salmonella spp associated with hospitalized equids often possess more antimicrobial resistance determinants than do Salmonella spp isolated from healthy horses in the general population. There is little evidence to suggest that resistant salmonellae are more virulent than nonresistant forms. MDR forms of Salmonella complicate the selection of appropriate antimicrobials when they are indicated, however. Furthermore, the use of some antimicrobials may apply selection pressure toward enhanced ability of MDR Salmonella to colonize equine patients. Further research should help to elucidate the risky uses of antimicrobials in the hospital setting and define the role of disinfectants and treatments such as NSAIDs in the ecology of MDR forms of nosocomial infections, including Salmonella. In the meantime, thoughtful selection of when and how to use antimicrobials in equine patients, together with deliberate selection of which antimicrobials to use based on monitoring data and other factors, such as safety and spectrum, is advised.  
  Address Animal and Plant Health Inspection Service, Veterinary Services, Centers for Epidemiology and Animal Health, United States Department of Agriculture, 2150 Centre Avenue, Building MS 2E7, Fort Collins, CO 80521, USA. david.a.dargatz@aphis.usda.gov  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0749-0739 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:15519820 Approved no  
  Call Number Equine Behaviour @ team @ Serial 2632  
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