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Author | Matzke, S.M.; Oubre, J.L.; Caranto, G.R.; Gentry, M.K.; Galbicka, G. | ||||
Title | Behavioral and immunological effects of exogenous butyrylcholinesterase in rhesus monkeys | Type | Journal Article | ||
Year | 1999 | Publication | Pharmacology, Biochemistry, and Behavior | Abbreviated Journal | Pharmacol Biochem Behav |
Volume | 62 | Issue | 3 | Pages | 523-530 |
Keywords | Animals; Antibody Formation/drug effects; Behavior, Animal/*drug effects; Butyrylcholinesterase/*immunology/pharmacokinetics/*pharmacology; Cognition/drug effects; Color Perception/drug effects; Conditioning, Operant/drug effects; Discrimination Learning/drug effects; Half-Life; Horses; Humans; Macaca mulatta; Male | ||||
Abstract | Although conventional therapies prevent organophosphate (OP) lethality, laboratory animals exposed to such treatments typically display behavioral incapacitation. Pretreatment with purified exogenous human or equine serum butyrylcholinesterase (Eq-BuChE), conversely, has effectively prevented OP lethality in rats and rhesus monkeys, without producing the adverse side effects associated with conventional treatments. In monkeys, however, using a commercial preparation of Eq-BuChE has been reported to incapacitate responding. In the present study, repeated administration of commercially prepared Eq-BuChE had no systematic effect on behavior in rhesus monkeys as measured by a six-item serial probe recognition task, despite 7- to 18-fold increases in baseline BuChE levels in blood. Antibody production induced by the enzyme was slight after the first injection and more pronounced following the second injection. The lack of behavioral effects, the relatively long in vivo half-life, and the previously demonstrated efficacy of BuChE as a biological scavenger for highly toxic OPs make BuChE potentially more effective than current treatment regimens for OP toxicity. | ||||
Address | Walter Reed Army Institute of Research, Washington, DC 20307-5100, USA | ||||
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Language | English | Summary Language | Original Title | ||
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ISSN | 0091-3057 | ISBN | Medium | ||
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Notes | PMID:10080246 | Approved | no | ||
Call Number | Equine Behaviour @ team @ | Serial | 4064 | ||
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Author | Clutton-Brock, T.H.; Parker, G.A. | ||||
Title | Punishment in animal societies | Type | Journal Article | ||
Year | 1995 | Publication | Abbreviated Journal | Nature | |
Volume | 373 | Issue | 6511 | Pages | 209-216 |
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Abstract | Although positive reciprocity (reciprocal altruism) has been a focus of interest in evolutionary biology, negative reciprocity (retaliatory infliction of fitness reduction) has been largely ignored. In social animals, retaliatory aggression is common, individuals often punish other group members that infringe their interests, and punishment can cause subordinates to desist from behaviour likely to reduce the fitness of dominant animals. Punishing strategies are used to establish and maintain dominance relationships, to discourage parasites and cheats, to discipline offspring or prospective sexual partners and to maintain cooperative behaviour. | ||||
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Notes | 10.1038/373209a0 | Approved | no | ||
Call Number | Equine Behaviour @ team @ | Serial | 4838 | ||
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Author | Marinier, S.L.; Alexander, A.J.; Waring, G.H. | ||||
Title | Flehmen behaviour in the domestic horse: Discrimination of conspecific odours | Type | Journal Article | ||
Year | 1988 | Publication | Applied Animal Behaviour Science | Abbreviated Journal | Appl. Anim. Behav. Sci. |
Volume | 19 | Issue | 3-4 | Pages | 227-237 |
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Abstract | American Saddlebred horses were used to test the responses of domestic horses to the odours of conspecifics. In all cases the odours were tested in the absence of the donor animal. Thus the test animal's behavioural responses were concentrated on the olfactory stimuli, and possible interference from donor behaviour was eliminated. Stallions were significantly more responsive than mares and geldings. This was shown in both flehmen and sniffing behaviour to urine/vaginal secretions and in sniffing behaviour to faecal samples. Only stallions were used for subsequent tests. Stallions showed no significant differences in response to the odour of urine/vaginal secretions of an oestrus mare from that when she was not in season. Parameters used for analysis of data were frequency, latency and duration of flehmen as well as duration of responsiveness to samples. In testing for differences in odours between individual mares, two methods were used. The stallions differentiated between samples from individual mares. In some cases this differentiation was exhibited when the stallions were merely presented with the two samples in sequence. In other cases statistically significant differences in response to the odours were shown only by simultaneous presentation of the two samples to the test stallion. Parameters used for data analysis were frequency and duration of flehmen and duration of responsiveness. | ||||
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Call Number | refbase @ user @ | Serial | 507 | ||
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Author | Raquel Monclús; Heiko G. Rödel | ||||
Title | Influence of Different Individual Traits on Vigilance Behaviour in European Rabbits | Type | Journal Article | ||
Year | 2009 | Publication | Ethology | Abbreviated Journal | Ethology |
Volume | 115 | Issue | 8 | Pages | 758-766 |
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Abstract | An animal's level of vigilance depends on various environmental factors such as predator presence or the proximity of conspecific competitors. In addition, several individual traits may influence vigilance. We investigated the effects of body condition, social rank and the state of pregnancy on individual vigilance (scanning) rates in individually marked European rabbits (Oryctolagus cuniculus) of a field enclosure population. We found lower rates in young rabbits than in adult females, but male and female juveniles did not differ. Vigilance of juveniles was positively correlated with their age-dependent body mass (used as a measure of body condition), i.e. young rabbits with lower body condition scanned less. We suggest that juveniles with low body condition were trading off vigilance against feeding to maximise their growth. In contrast, there was no significant correlation between body mass and vigilance in adult females. Adult females increased scanning rates during late pregnancy, which might constitute a behavioural compensation because of their lower capacity to escape predator attacks. In addition, adult females with low social ranks scanned more than high ranking individuals, likely because of their higher risk of attacks by conspecifics. In summary, our results highlight various individual characteristics that influence vigilance behaviour in European rabbits. | ||||
Address | Unidad de Zoologa, Dpto. Biologa, Universidad Autnoma de Madrid, Madrid, Spain; Department of Animal Physiology, University of Bayreuth, Bayreuth, Germany | ||||
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Publisher | Place of Publication | © 2009 Blackwell Verlag GmbH | Editor | ||
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Call Number | Equine Behaviour @ team @ | Serial | 4994 | ||
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Author | Gallup, G.G.J. | ||||
Title | Do minds exist in species other than our own? | Type | Journal Article | ||
Year | 1985 | Publication | Neuroscience and Biobehavioral Reviews | Abbreviated Journal | Neurosci Biobehav Rev |
Volume | 9 | Issue | 4 | Pages | 631-641 |
Keywords | Animals; Awareness; *Behavior, Animal; Child Psychology; Child, Preschool; *Cognition; Consciousness; Evolution; Humans; Infant; Language; Pan troglodytes; Philosophy; Psychological Theory; Species Specificity | ||||
Abstract | An answer to the question of animal awareness depends on evidence, not intuition, anecdote, or debate. This paper examines some of the problems inherent in an analysis of animal awareness, and whether animals might be aware of being aware is offered as a more meaningful distinction. A framework is presented which can be used to make a determination about the extent to which other species have experiences similar to ours based on their ability to make inferences and attributions about mental states in others. The evidence from both humans and animals is consistent with the idea that the capacity to use experience to infer the experience of others is a byproduct of self-awareness. | ||||
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Language | English | Summary Language | Original Title | ||
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ISSN | 0149-7634 | ISBN | Medium | ||
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Notes | PMID:4080281 | Approved | no | ||
Call Number | Equine Behaviour @ team @ | Serial | 2808 | ||
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Author | Pick, D.F.; Lovell, G.; Brown, S.; Dail, D. | ||||
Title | Equine color perception revisited | Type | Journal Article | ||
Year | 1994 | Publication | Applied Animal Behaviour Science | Abbreviated Journal | Appl. Anim. Behav. Sci. |
Volume | 42 | Issue | 1 | Pages | 61-65 |
Keywords | Equine; Color perception; Dichromat | ||||
Abstract | An attempt to replicate Grzimek (1952; Z. Tierpsychol., 27: 330-338) is reported where a Quarter-Horse mare chose between colored and gray stimuli for food reinforcement. Stimuli varied across a broad range of reflectance values. A double-blind procedure with additional controls for auditory, olfactory, tactile, and position cues was used. The subject could reliably discriminate blue (462 nm) vs. gray, and red (700 nm) vs. gray without regard to reflectance (P<0.001), but could not discriminate green (496 nm) vs. gray. It is suggested that horses are dichromats in a manner similar to swine and cattle. | ||||
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Call Number | Equine Behaviour @ team @ | Serial | 4368 | ||
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Author | Osman, F.; Zeitler-Feicht, M.; Fink, G. W.; Arnhard, S.; Krüger, K. | ||||
Title | Überprüfung der lichten Weiten von Gitterstäben in der Pferdehaltung [Analysing demands for the clear widths of lattice bars in horse husbandry] | Type | Journal Article | ||
Year | 2020 | Publication | Abbreviated Journal | Landtechnik [Agricultural Engineering] | |
Volume | 75 | Issue | 1 | Pages | 24-33 |
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Abstract | An Gitterstäben, die in der Pferdehaltung an verschiedenen Stellen verwendet werden, können sich Pferde verletzen, wenn sie ihre Köpfe oder ihre Hufe hindurchstecken und nicht zurückziehen können. Um das Verletzungsrisiko zu reduzieren sind lichte Weiten und Materialstärken von Gitterstäben so zu wählen, dass Pferdeköpfe und -hufe entweder nicht zwischen den Freiräumen hindurchpassen oder aber gefahrlos wieder zurückgezogen werden können. Die bisherige Forschung liefert jedoch keine belastbaren Aussagen zu Stababständen (senkrecht und waagerecht), die für Pferde ungefährlich sind. Die in der Praxis verwendeten und in der Literatur empfohlenen Gitterstababstände beruhen auf Erfahrungswerten und technischen Materialeigenschaften. In der vorliegenden Untersuchung wurden Pferdeköpfe und -hufe von insgesamt 480 Pferden (233 Stuten, 204 Wallache und 43 Hengste) von 23 verschiedenen Rassen vermessen, um auf Grundlage der Anatomie der Pferde Aussagen über die Eignung von marktüblichen Stababständen in der Praxis treffen zu können. Es stellte sich heraus, dass bei senkrechten Gitterstäben eine lichte Weite von nicht mehr als 5 cm für alle Pferde ab einem Stockmaß von 110 cm und einem Alter von zwei Jahren als sicher bezeichnet werden kann. Bei waagerechten Gitterstäben erwies sich eine lichte Weite von genau 17 cm als sicher. Dies gilt für alle Pferde ab einem Alter von zwei Jahren oder ab einem Stockmaß von 148 cm. Kritisch sind die lichten Weiten von Panels zu beurteilen. Hier zeigte sich, dass die handelsüblichen Abstände der Gitterstäbe für die meisten Pferde eine erhebliche Gefahr darstellen. Wenn die Pferde beispielsweise versuchen außerhalb der Panels zu fressen und dabei ihren Kopf durch die Gitterstäbe stecken, kann es leicht passieren, dass sie sich mit dem Kopf zwischen den Gitterstäben verklemmen. [At bars, used in various places in horse husbandry, horses can hurt themselves when retracting their heads or hooves after pushing them through the interspaces. In order to reduce the risk of injury, the clear widths and material thicknesses of bars should be chosen so that horse heads and hooves either cannot pass between the spaces or can be retracted safely. However, research to date has not provided any reliable information on bar width (vertical and horizontal) that is safe for horses. Grid bar width used in practice and recommended in the literature is based on empirical values and technical material properties. In this study, heads and hooves of 480 horses (233 mares, 204 geldings and 43 stallions) of 23 breeds were measured for making statements about the suitability of standard bar width, when considering the anatomy of the horse. It turned out that for vertical bars, an interspace of no more than five centimetres can be considered to be safe for all horses of a height of 110 centimetres and an age of two years and more. With horizontal lattice bars, a clear width of exactly 17 centimetres proved to be safe. This applies to all horses of a height of 148 centimetres and an age of two years or more. The clear widths of panels must be considered critical for horse welfare. When horses, for example, try to eat outside the panels and put their head through the bars, they may get stuck.] |
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Call Number | Equine Behaviour @ team @ | Serial | 6595 | ||
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Author | Maury, M.; Murphy, K.; Kumar, S.; Mauerer, A.; Lee, G. | ||||
Title | Spray-drying of proteins: effects of sorbitol and trehalose on aggregation and FT-IR amide I spectrum of an immunoglobulin G | Type | Journal Article | ||
Year | 2005 | Publication | European Journal of Pharmaceutics and Biopharmaceutics | Abbreviated Journal | Eur. J. Pharm. Biopharm. |
Volume | 59 | Issue | 2 | Pages | 251-261 |
Keywords | Immunoglobulin; Spray-drying; Stabilization; Sorbitol; Trehalose; Water replacement | ||||
Abstract | An immunoglobulin G (IgG) was spray-dried on a Büchi 190 laboratory spray-dryer at inlet and outlet air temperatures of 130 and 190°C, respectively. The IgG solution contains initially 115mg/ml IgG plus 50mg/ml sorbitol. After dialysis, at least 80% of low molecular weight component was removed. After spray-drying the dialyzed IgG and immediate redissolution of the powder, an increase in aggregates from 1 to 17% occurred. A major shift towards increase β-sheet structure was detected in the spray-dried solid, which, however, reverted to native structure on redissolution of the powder. A correlation between aggregation determined by size exclusion chromatography and alterations in secondary structure determined by Fourier transformation infra-red spectroscopy could not therefore be established. On spray-drying a non-dialyzed, sorbitol-containing IgG only some 0.7% aggregates were formed. The sorbitol is therefore evidently able to stabilize partially the IgG during the process of spray-drying. Addition of trehalose to the liquid feed produced quantitatively the same stabilizing action on the IgG during spray-drying as did the sorbitol. This finding again points towards a water replacement stabilization mechanism. The IgG spray-dried powder prepared from the dialyzed liquid feed showed continued substantial aggregation on dry storage at 25°C. This was substantially less in the non-dialyzed, sorbitol-containing spray-dried powder. Addition of trehalose to both dialyzed and non-dialyzed system produced substantial improvement in storage stability and reduction in aggregate formation in storage. The quantitative stabilizing effect of the trehalose was only slightly higher than that of the sorbitol. Taken together, these results indicate that both the sorbitol and trehalose stabilize the IgG primarily by a water replacement mechanism rather than by glassy immobilization. The relevance of this work is its questioning of the importance of the usually considered dominance of glassy stabilization of protein in dried systems of high glass transition temperature, such as trehalose. The low glass transition temperature sorbitol produces almost equal process and storage stability in this case. | ||||
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ISSN | 0939-6411 | ISBN | Medium | ||
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Notes | Approved | no | |||
Call Number | Equine Behaviour @ team @ | Serial | 6515 | ||
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Author | Lloyd, A.S.; Martin, J.E.; Bornett-Gauci, H.L.I.; Wilkinson, R.G. | ||||
Title | Horse personality: Variation between breeds | Type | Journal Article | ||
Year | 2008 | Publication | Applied Animal Behaviour Science | Abbreviated Journal | Appl. Anim. Behav. Sci. |
Volume | 112 | Issue | 3-4 | Pages | 369-383 |
Keywords | Horse personality; Breed; Assessment; Questionnaire survey; Animal | ||||
Abstract | Anecdotal evidence from horse owners and handlers suggests the existence of breed typical behaviour and personality in horses. This is further supported by current research on heritability of personality characteristics in a range of species. The Horse Personality Questionnaire (HPQ) is a 25-item rating method that has previously been shown to be reliable for the assessment of personality in horses. Principal component analysis on HPQ data has identified six underlying personality components in horses. These are Dominance, Anxiousness, Excitability, Protection, Sociability and Inquisitiveness. Using the HPQ a survey of 1223 horses of eight different breeds was completed. Data were analysed to explore any differences in personality between breeds across the six personality components. Breed differences in personality were identified, and it was noted that variability between breeds varied between personality components. Anxiousness and Excitability showed the most variation between breeds, whilst Dominance and Protection showed the least variance. The results identified breed typical personalities that were comparable to results from previous studies as well as anecdotal evidence provided by the popular equine literature. The results are discussed in terms of the potential selection pressures that may have resulted in these differences. | ||||
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Call Number | Equine Behaviour @ team @ | Serial | 4279 | ||
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Author | Smith, L.A.; Wells, K.L.; Marion, G.; Swain, D.L.; Hutchings, M.R. | ||||
Title | Effects of group composition on the grazing behaviour of herbivores | Type | Journal Article | ||
Year | Publication | Animal Behaviour. | Abbreviated Journal | Anim. Behav. | |
Volume | In Press, Corrected Proof | Issue | Pages | ||
Keywords | grazing; group composition; herbivore; individual behaviour; physiological state | ||||
Abstract | Animal behaviour is often a function of the animal's physiological state. Groups of animals will often contain individuals with a range of physiological states and the grazing behaviour of herbivores is affected by their physiological state. This study compared the grazing decisions of animals in groups of single and mixed physiological states. Using a grazing model that simulated individual herbivore behaviour in relation to environmental distributions of forage resource (grass) and parasites (faeces), we tested the hypothesis that an animal's level of parasite exposure via the faecal-oral route is affected by the composition of physiological states in the group. Four physiological states were considered: parasite-naïve, parasitized, lactating and parasite-immune animals. Baseline parasite exposure levels for each state were generated by simulating single-state groups and were compared to simulations of each of the six two-state combinations. In single-state groups parasitized animals had the least and lactating animals had the greatest levels of parasite exposure. When co-grazing with lactating animals, parasitized, immune and naïve animals increased their parasite exposure, relative to single-state groups. When co-grazing with parasitized animals, lactating, immune and naïve animals reduced their parasite exposure, relative to single-state groups. There was no difference in parasite exposure of the immune or naïve animals co-grazing together when compared to the single-state groups. These results highlight the need to recognize the impact of the individual when studying group-living animals. | ||||
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ISSN | 0003-3472 | ISBN | Medium | ||
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Call Number | Equine Behaviour @ team @ | Serial | 5155 | ||
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