Records |
Author |
Domjan, M. |
Title |
Determinants of the enhancement of flavored-water intake by prior exposure |
Type |
Journal Article |
Year |
1976 |
Publication |
Journal of Experimental Psychology. Animal Behavior Processes |
Abbreviated Journal ![sorted by Abbreviated Journal field, ascending order (up)](img/sort_asc.gif) |
J Exp Psychol Anim Behav Process |
Volume |
2 |
Issue |
1 |
Pages |
17-27 |
Keywords |
Animals; Arousal; *Awareness; Behavior, Animal; *Cognition; *Drinking Behavior; Environment; Escape Reaction; Fear; Male; Rats; Saccharin/administration & dosage; *Taste; Thirst; Time Factors; Water Deprivation |
Abstract |
The intake of a 2.0% sodium saccharin solution in rats was observed to increase as a function of both the number (Experiment 1) and the duration (Experiment 3) of prior periods of access to the saccharin flavor, but did not increase when subjects were maintained on a fluid deprivation procedure in the absence of saccharin exposure (Experiment 2). The enhancement of intake was further influenced by the schedule of saccharin preexposures in the absence of variations in the amount of solution tasted (Experiment 4). The effect was not a function of the opportunity for subjects to determine their own pattern of contact with the saccharin flavor, the opportunity for association of the flavor with hunger and thirst reduction, or the amount of saccharin swallowed during preexposure (Experiment 5). These results suggest that mere exposure to a flavored solution is sufficient to increase subsequent intakes. The phenomenon is discussed in terms of the attenuation of neophobia elicited by the novelty of flavored solutions. |
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Edition |
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ISSN |
0097-7403 |
ISBN |
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Conference |
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Notes |
PMID:1249524 |
Approved |
no |
Call Number |
Equine Behaviour @ team @ |
Serial |
2790 |
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Author |
Mitchell, D.; Kirschbaum, E.H.; Perry, R.L. |
Title |
Effects of neophobia and habituation on the poison-induced avoidance of exteroceptive stimuli in the rat |
Type |
Journal Article |
Year |
1975 |
Publication |
Journal of Experimental Psychology. Animal Behavior Processes |
Abbreviated Journal ![sorted by Abbreviated Journal field, ascending order (up)](img/sort_asc.gif) |
J Exp Psychol Anim Behav Process |
Volume |
1 |
Issue |
1 |
Pages |
47-55 |
Keywords |
Animals; Avoidance Learning/*drug effects; *Awareness; *Cognition; Conditioning, Operant; Feeding Behavior/drug effects; *Habituation, Psychophysiologic; Injections, Intraperitoneal; Lithium/administration & dosage/poisoning; Male; Rats; *Taste; Time Factors; *Visual Perception |
Abstract |
Two experiments on the role of neophobia in poison-induced aversions to exteroceptive stimuli are reported. In Experiment 1, rats were given either 10 or 25 days of habituation to the test situation prior to conditioning. Those animals with the longer habituation period avoided a complex of novel exteroceptive stimuli while those with the shorter habituation period did not. In Experiment 2 rats initially avoided the more novel of two containers, but gradually came to eat equal amounts from both. A single pairing of toxicosis with consumption from either the novel or the familiar container reinstated the avoidance of the novel container in both cases. The results were discussed in terms of an interaction between habituation and conditioning procedures. It was suggested that previously reported differences between interoceptive and exteroceptive conditioning effects may have been influenced by the differential novelty of the two classes of stimuli in the test situation. It was further suggested that non-contingently poisoned control groups should routinely be included in poison avoidance conditioning studies. |
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0097-7403 |
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Notes |
PMID:1151289 |
Approved |
no |
Call Number |
Equine Behaviour @ team @ |
Serial |
2791 |
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Author |
Dierenfeld, E.S. |
Title |
Vitamin E in exotics: effects, evaluation and ecology |
Type |
Journal Article |
Year |
1994 |
Publication |
The Journal of Nutrition |
Abbreviated Journal ![sorted by Abbreviated Journal field, ascending order (up)](img/sort_asc.gif) |
J Nutr |
Volume |
124 |
Issue |
12 Suppl |
Pages |
2579s-2581s |
Keywords |
Animal Feed/*analysis; Animals; Animals, Zoo/blood/*metabolism; Antelopes/blood/metabolism; Birds/blood/metabolism; Deer/blood/metabolism; Elephants/blood/metabolism; Equidae/blood/metabolism; Perissodactyla/blood/metabolism; Vitamin E/*administration & dosage/analysis/blood; Vitamin E Deficiency/pathology/physiopathology/veterinary |
Abstract |
The pathophysiology and lesions associated with vitamin E deficiency are similar between domestic and exotic species, and circulating plasma concentrations are also similar between comparable groups. However, many ecological variables must be considered for the most relevant comparisons. Tissue values of vitamin E, apart from plasma, are unknown for most exotics. Dietary vitamin E requirements of exotic species and domestics appear to differ; based on natural foodstuff analyses and clinical observations, between 50 and 200 mg vitamin E/kg DM are necessary to prevent vitamin E deficiency, 5- to 10-fold higher than current livestock recommendations. |
Address |
Department of Nutrition, Wildlife Health Center, Wildlife Conservation Society, Bronx, NY 10460 |
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English |
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Abbreviated Series Title |
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Edition |
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ISSN |
0022-3166 |
ISBN |
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Medium |
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Conference |
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Notes |
PMID:7996243 |
Approved |
no |
Call Number |
Equine Behaviour @ team @ |
Serial |
2661 |
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Author |
Crosby, M.B.; Svenson, J.L.; Zhang, J.; Nicol, C.J.; Gonzalez, F.J.; Gilkeson, G.S. |
Title |
Peroxisome proliferation-activated receptor (PPAR)gamma is not necessary for synthetic PPARgamma agonist inhibition of inducible nitric-oxide synthase and nitric oxide |
Type |
Journal Article |
Year |
2005 |
Publication |
The Journal of pharmacology and experimental therapeutics |
Abbreviated Journal ![sorted by Abbreviated Journal field, ascending order (up)](img/sort_asc.gif) |
J Pharmacol Exp Ther |
Volume |
312 |
Issue |
1 |
Pages |
69-76 |
Keywords |
Animals; Cell Line; Gene Expression/drug effects; Macrophages/drug effects/metabolism; Mice; Mice, Inbred C57BL; Nitric Oxide/*metabolism; Nitric Oxide Synthase/*metabolism; Nitric Oxide Synthase Type II; PPAR delta/metabolism; PPAR gamma/*agonists/deficiency; Thiazolidinediones/pharmacology |
Abstract |
Peroxisome proliferation-activated receptor (PPAR)gamma agonists inhibit inducible nitric-oxide synthase (iNOS), tumor necrosis factor-alpha, and interleukin-6. Because of these effects, synthetic PPARgamma agonists, including thiazolidinediones, are being studied for their impact on inflammatory disease. The anti-inflammatory concentrations of synthetic PPARgamma agonists range from 10 to 50 microM, whereas their binding affinity for PPARgamma is in the nanomolar range. The specificity of synthetic PPARgamma agonists for PPARgamma at the concentrations necessary for anti-inflammatory effects is thus in question. We report that PPARgamma is not necessary for the inhibition of iNOS by synthetic PPARgamma agonists. RAW 264.7 macrophages possess little PPARgamma, yet lipopolysaccharide (LPS)/interferon (IFN)gamma-induced iNOS was inhibited by synthetic PPARgamma agonists at 20 microM. Endogenous PPARgamma was inhibited by the transfection of a dominant-negative PPARgamma construct into murine mesangial cells. In the transfected cells, synthetic PPARgamma agonists inhibited iNOS production at 10 microM, similar to nontransfected cells. Using cells from PPARgamma Cre/lox conditional knockout mice, baseline and LPS/IFNgamma-induced nitric oxide levels were higher in macrophages lacking PPARgamma versus controls. However, synthetic PPARgamma agonists inhibited iNOS at 10 microM in the PPARgamma-deficient cells, similar to macrophages from wild-type mice. These results indicate that PPARgamma is not necessary for inhibition of iNOS expression by synthetic PPARgamma agonists at concentrations over 10 microM. Intrinsic PPARgamma function, in the absence of synthetic agonists, however, may play a role in inflammatory modulation. |
Address |
Department of Medicine, Medical University of South Carolina, Charleston, SC 29425, USA |
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English |
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Series Editor |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0022-3565 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
PMID:15356214 |
Approved |
no |
Call Number |
refbase @ user @ |
Serial |
73 |
Permanent link to this record |
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Author |
Schwarzenberger, F.; Mostl, E.; Bamberg, E.; Pammer, J.; Schmehlik, O. |
Title |
Concentrations of progestagens and oestrogens in the faeces of pregnant Lipizzan, trotter and thoroughbred mares |
Type |
Journal Article |
Year |
1991 |
Publication |
Journal of reproduction and fertility. Supplement |
Abbreviated Journal ![sorted by Abbreviated Journal field, ascending order (up)](img/sort_asc.gif) |
J Reprod Fertil Suppl |
Volume |
44 |
Issue |
|
Pages |
489-499 |
Keywords |
Animals; Estrogens/*analysis; Feces/*chemistry; Female; Gestational Age; Horses/*metabolism; Immunoenzyme Techniques; Labor, Obstetric; Pregnancy; Pregnancy, Animal/*metabolism; Pregnenes/analysis; Progestins/*analysis |
Abstract |
Faecal samples were collected at weekly intervals from pregnant Lipizzan mares during Weeks 7-16 following mating and from Lipizzan, Trotter and Thoroughbred mares during the last 3 months of gestation. After parturition, samples were taken daily from the Thoroughbred mares for another 6 days. Non-pregnant mares served as controls. The concentrations of unconjugated oestrogens (Eg), 20 alpha-OH-progestagens (20 alpha-G) and 20 beta-OH-progestagens (20 beta-G) were measured by enzyme immunoassay. In the faeces of Lipizzan mares, immunoreactive progestagens were significantly (P less than 0.01) elevated above the levels in non-pregnant mares by Week 11, and Eg by Week 13 of pregnancy onwards. During the last 3 months of gestation, concentrations of Eg were significantly higher in Trotter mares than in Lipizzan and Thoroughbred mares. Concentrations of 20 alpha-G and 20 beta-G increased to maximal values in the last month of gestation. There was no significant difference among the 3 breeds with respect to 20 alpha-G but, during the 10 weeks before parturition, concentrations of 20 beta-G in the Lipizzan mares were significantly lower (P less than 0.05) than those in the Thoroughbred mares. They were also significantly lower than those of the Trotter mares during the last 4 weeks of gestation. After parturition, the concentrations of Eg and progestagens had declined to baseline values by Days 3 and 4 respectively. From these results we conclude that high concentrations of progestagens with 20 alpha- and 20 beta-hydroxyl groups are present in the faeces of pregnant mares, especially during the last month of gestation. |
Address |
Institut fur Biochemie, Veterinary Medical University, Vienna, Austria |
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English |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0449-3087 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
PMID:1795293 |
Approved |
no |
Call Number |
refbase @ user @ |
Serial |
322 |
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Author |
Feist, J.D.; McCullough, D.R. |
Title |
Reproduction in feral horses |
Type |
Journal Article |
Year |
1975 |
Publication |
Journal of Reproduction and Fertility. Supplement |
Abbreviated Journal ![sorted by Abbreviated Journal field, ascending order (up)](img/sort_asc.gif) |
J Reprod Fertil Suppl |
Volume |
|
Issue |
23 |
Pages |
13-18 |
Keywords |
Age Factors; Animals; Female; Horses/*physiology; Leadership; Male; Maternal Behavior; Population; Reproduction; *Sexual Behavior, Animal; Social Dominance; Sucking Behavior |
Abstract |
A behavioural study of feral horses was conducted on the Pryor Mountain Wild Horse Range in the western United States. All 270 horses on the Range were identified individually. The sex ratio was nearly balanced. Foal to adult female ratio was 43-2:100. Morality was concentrated among foals and old horses. Horses were organized as forty-four harem groups each with a dominant stallion, one to two immature stallions, one to three immature mares, one to three adult mares and their yearling and foal offspring, and 23 bachelor groups of one to eight stallions. Harem groups were quite stable year-round because of dominance and leadership by the stallions and group fidelity by mares and their offsring. Most changes occurred during the breeding season and involved immature females. Defeat of dominant stallions was infrequent. Immature males were tolerated because of their submissive behaviour. Bachelor stallion groups were inherently unstable. Mares came into heat after foaling in May/June, and were mated by harem stallions only. |
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English |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Edition |
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ISSN |
0449-3087 |
ISBN |
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Medium |
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Area |
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Conference |
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Notes |
PMID:1060766 |
Approved |
no |
Call Number |
refbase @ user @ |
Serial |
1964 |
Permanent link to this record |
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Author |
Lucas, Z.; Raeside, J.I.; Betteridge, K.J. |
Title |
Non-invasive assessment of the incidences of pregnancy and pregnancy loss in the feral horses of Sable Island |
Type |
Journal Article |
Year |
1991 |
Publication |
Journal of Reproduction and Fertility. Supplement |
Abbreviated Journal ![sorted by Abbreviated Journal field, ascending order (up)](img/sort_asc.gif) |
J Reprod Fertil Suppl |
Volume |
44 |
Issue |
|
Pages |
479-488 |
Keywords |
Abortion, Veterinary/*epidemiology; Animals; Animals, Wild/*physiology; Atlantic Islands; Estrogens/analysis; Feces/chemistry; Female; Fertilization; Gestational Age; Horse Diseases/*epidemiology; Horses; Incidence; Pregnancy; *Pregnancy, Animal |
Abstract |
Field observations of 400 totally unmanaged feral horses on Sable Island, Nova Scotia, were complemented by oestrogen determinations in faecal samples from 154 identified females over a 4-year period (454 mare-years). Of mares that were sampled throughout the year and subsequently produced foals, 92.1% exhibited elevated faecal oestrogens between 15 October and 30 March. The results confirm that faecal oestrogens are a useful indicator of pregnancy after approximately 120 days gestation. Distribution of foaling resembled that seen in other feral populations, with 95% of births occurring from April through July. The foaling rate for mares aged 3 years or older was 62.0%, with 50.7% of mares foaling in 3 or 4 years. Foaling rates were low (4.1%) in mares bred as yearlings and rose with age to 70.8% in those bred as 4-year-olds. Fetal loss after Day 120 was deduced from faecal oestrogens to be 26.0% overall, with marked variation from year to year (9.6-37.3%) and with age (70.0% in those bred as yearlings, decreasing to 5.6% in those bred as 4-year-olds). Of 58 mares aged 2 years or older that were sampled every year, about half (49.6%) the barren years were attributable to fetal loss after 120 days gestation. All mares conceived in at least 2 of the 4 years, suggesting that pregnancy loss, even after Day 120, is as important as failure to conceive in causing barren years. |
Address |
Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph, Canada |
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English |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0449-3087 |
ISBN |
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Medium |
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Area |
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Conference |
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Notes |
PMID:1795292 |
Approved |
no |
Call Number |
Equine Behaviour @ team @ |
Serial |
2247 |
Permanent link to this record |
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Author |
Sinclair, M.; Buhrmann, G.; Gummow, B. |
Title |
An epidemiological investigation of the African horsesickness outbreak in the Western Cape Province of South Africa in 2004 and its relevance to the current equine export protocol |
Type |
Journal Article |
Year |
2006 |
Publication |
Journal of the South African Veterinary Association |
Abbreviated Journal ![sorted by Abbreviated Journal field, ascending order (up)](img/sort_asc.gif) |
J S Afr Vet Assoc |
Volume |
77 |
Issue |
4 |
Pages |
191-196 |
Keywords |
African Horse Sickness/diagnosis/*epidemiology; African horse sickness virus/*isolation & purification; Animals; Ceratopogonidae/virology; Diagnosis, Differential; Disease Outbreaks/*veterinary; Female; Horses; Insect Vectors/virology; Male; Prevalence; Retrospective Studies; Sentinel Surveillance; South Africa/epidemiology; Viral Vaccines/administration & dosage |
Abstract |
African Horsesickness (AHS) is a controlled disease in South Africa. The country is divided into an infected area and a control area. An outbreak of AHS in the control area can result in a ban of exports for at least 2 years. A retrospective epidemiological study was carried out on data collected during the 2004 AHS outbreak in the surveillance zone of the AHS control area in the Western Cape Province. The objective of this study was to describe the 2004 outbreak and compare it with the 1999 AHS outbreak in the same area. As part of the investigation, a questionnaire survey was conducted in the 30 km radius surrounding the index case. Spatial, temporal and population patterns for the outbreak are described. The investigation found that the outbreak occurred before any significant rainfall and that the main AHS vector (Culicoides imicola) was present in abundance during the outbreak. Furthermore, 63% of cases occurred at temperatures < or = 15 degrees C, the Eerste River Valley was a high risk area, only 17% of owners used vector protection as a control measure and 70% of horses in the outbreak area were protected by means of vaccination at the start of the outbreak. The study revealed that the current AHS control measures do not function optimally because of the high percentage of vaccinated horses in the surveillance zone, which results in insufficient sentinel animals and the consequent failure of the early warning system. Alternative options for control that allow continued export are discussed in the paper. |
Address |
State Veterinarian Epidemiology, Elsenburg, South Africa. marnas@elsenburg.com |
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English |
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Series Issue |
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Edition |
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ISSN |
1019-9128 |
ISBN |
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Medium |
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Expedition |
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Conference |
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Notes |
PMID:17458343 |
Approved |
no |
Call Number |
Equine Behaviour @ team @ |
Serial |
2354 |
Permanent link to this record |
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Author |
Grubb, T.L.; Foreman, J.H.; Benson, G.J.; Thurmon, J.C.; Tranquilli, W.J.; Constable, P.D.; Olson, W.O.; Davis, L.E. |
Title |
Hemodynamic effects of calcium gluconate administered to conscious horses |
Type |
Journal Article |
Year |
1996 |
Publication |
Journal of veterinary internal medicine / American College of Veterinary Internal Medicine |
Abbreviated Journal ![sorted by Abbreviated Journal field, ascending order (up)](img/sort_asc.gif) |
J Vet Intern Med |
Volume |
10 |
Issue |
6 |
Pages |
401-404 |
Keywords |
Animals; Blood Pressure/drug effects/physiology; Calcium/blood; Calcium Gluconate/administration & dosage/*pharmacology; Cardiac Output/drug effects/physiology; Consciousness/*physiology; Dose-Response Relationship, Drug; Female; Heart Rate/drug effects/physiology; Hemodynamic Processes/*drug effects/physiology; Horses/blood/*physiology; Infusions, Intravenous; Male; Myocardial Contraction/drug effects/physiology; Respiration/drug effects/physiology; Stroke Volume/drug effects/physiology; Time Factors |
Abstract |
Calcium gluconate was administered to conscious horses at 3 different rates (0.1, 0.2, and 0.4 mg/kg/min for 15 minutes each). Serum calcium concentrations and parameters of cardiovascular function were evaluated. All 3 calcium administration rates caused marked increases in both ionized and total calcium concentrations, cardiac index, stroke index, and cardiac contractility (dP/dtmax). Mean arterial pressure and right atrial pressure were unchanged; heart rate decreased markedly during calcium administration. Ionized calcium concentration remained between 54% and 57% of total calcium concentration throughout the study. We conclude that calcium gluconate can safely be administered to conscious horses at 0.1 to 0.4 mg/kg/min and that administration will result in improved cardiac function. |
Address |
Department of Veterinary Clinical Medicine, University of Illinois at Urbana-Champaign, USA |
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English |
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Series Issue |
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Edition |
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ISSN |
0891-6640 |
ISBN |
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Expedition |
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Conference |
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Notes |
PMID:8947873 |
Approved |
no |
Call Number |
refbase @ user @ |
Serial |
97 |
Permanent link to this record |
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Author |
Rietmann, T.R.; Stauffacher, M.; Bernasconi, P.; Auer, J.A.; Weishaupt, M.A. |
Title |
The association between heart rate, heart rate variability, endocrine and behavioural pain measures in horses suffering from laminitis |
Type |
Journal Article |
Year |
2004 |
Publication |
Journal of Veterinary Medicine. A, Physiology, Pathology, Clinical Medicine |
Abbreviated Journal ![sorted by Abbreviated Journal field, ascending order (up)](img/sort_asc.gif) |
J Vet Med A Physiol Pathol Clin Med |
Volume |
51 |
Issue |
5 |
Pages |
218-225 |
Keywords |
Animals; Anti-Inflammatory Agents, Non-Steroidal/administration & dosage; Autonomic Nervous System; Behavior, Animal; Electrophysiology/*methods; Endocrine System; Female; Heart Rate; Horse Diseases/blood/drug therapy/*physiopathology; Horses; Joint Diseases/physiopathology/*veterinary; Male; Pain/physiopathology/*veterinary; Pain Measurement/*veterinary; Predictive Value of Tests |
Abstract |
The objective of this study was to compare the stress response of horses suffering from laminitis after short- and long-term treatment with the intent to evaluate power spectral analysis of heart rate variability (HRV) for pain monitoring. Data were collected from 19 horses with acute or chronic exacerbating laminitis without known primary disease before and after treatment with non-steroidal anti-inflammatory drugs (NSAID). Recordings were carried out the day after admission to the equine hospital. Measurements were repeated on day 7 of the treatment. The recorded parameters included a clinical orthopaedic index (OLPI: Obel-grade plus hoof tester score), frequency of weight-shifting between contralateral limbs, mean beat-to-beat interval (R-R) duration, standard deviation of continuous R-R intervals, low- (LF) and high-frequency (HF) components of HRV, sympatho-vagal balance (LF/HF), and plasma concentration of cortisol, adrenalin and noradrenalin. The LF represents mainly sympathetic influences on the heart whereas HF is mediated by the parasympathetic tone. Weight-shifting and OLPI decreased significantly with treatment. The LF normalized units (n.u.) decreased after NSAID from 60.41 +/- 21.42 to 51.12 +/- 19.81 and was 49.33 +/- 22.64 on day 7, whereas HF n.u. increased from 35.07 +/- 20.02 to 43.14 +/- 18.30 and was 45.98 +/- 23.00 on day 7. Hormone levels showed no tendency to change with treatment. The OLPI was only correlated with LF/HF, LF and HF (R = 0.57, 0.55 and -0.54 respectively). Significant negative correlations existed between HFn.u. and weight-shifting frequency (R = -0.37), HFn.u. and adrenalin (R = -0.47), and HFn.u. and noradrenalin (R = 0.33). The LFn.u. only correlated positively with adrenalin. Cortisol levels were poorly associated with the other parameters. Determination of the sympatho-vagal influences on cardiac function may offer complementary information for reliable assessment of pain and may represent a valuable alternative method to catecholamine measurements. |
Address |
Equine Hospital, Faculty of Veterinary Medicine, University of Zurich, Winterthurerstrasse 260, CH-8057 Zurich, Switzerland |
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English |
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Series Editor |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0931-184X |
ISBN |
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Area |
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Expedition |
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Conference |
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Notes |
PMID:15315700 |
Approved |
no |
Call Number |
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Serial |
1899 |
Permanent link to this record |