| |
Records |
Links |
|
Author |
Bykov, S.; Lednev, I.; Ianoul, A.; Mikhonin, A.; Munro, C.; Asher, S.A. |
|
| |
Title |
Steady-state and transient ultraviolet resonance Raman spectrometer for the 193-270 nm spectral region |
Type |
Journal Article |
| |
Year |
2005 |
Publication |
Applied Spectroscopy |
Abbreviated Journal |
Appl Spectrosc |
|
| |
Volume |
59 |
Issue |
12 |
Pages |
1541-1552 |
|
| |
Keywords |
Animals; Equipment Design; Equipment Failure Analysis; Horses; Kinetics; Metmyoglobin/*analysis; Myocardium/*metabolism; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet/*instrumentation/methods; Spectrum Analysis, Raman/*instrumentation/methods |
|
| |
Abstract |
We describe a state-of-the-art tunable ultraviolet (UV) Raman spectrometer for the 193-270 nm spectral region. This instrument allows for steady-state and transient UV Raman measurements. We utilize a 5 kHz Ti-sapphire continuously tunable laser (approximately 20 ns pulse width) between 193 nm and 240 nm for steady-state measurements. For transient Raman measurements we utilize one Coherent Infinity YAG laser to generate nanosecond infrared (IR) pump laser pulses to generate a temperature jump (T-jump) and a second Coherent Infinity YAG laser that is frequency tripled and Raman shifted into the deep UV (204 nm) for transient UV Raman excitation. Numerous other UV excitation frequencies can be utilized for selective excitation of chromophoric groups for transient Raman measurements. We constructed a subtractive dispersion double monochromator to minimize stray light. We utilize a new charge-coupled device (CCD) camera that responds efficiently to UV light, as opposed to the previous CCD and photodiode detectors, which required intensifiers for detecting UV light. For the T-jump measurements we use a second camera to simultaneously acquire the Raman spectra of the water stretching bands (2500-4000 cm(-1)) whose band-shape and frequency report the sample temperature. |
|
| |
Address |
Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA |
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
|
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
0003-7028 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
PMID:16390595 |
Approved |
no |
|
| |
Call Number |
Equine Behaviour @ team @ |
Serial |
3767 |
|
| Permanent link to this record |
| |
|
| |
|
Author |
Hampton, R.R. |
|
| |
Title |
Rhesus monkeys know when they remember |
Type |
Journal Article |
| |
Year |
2001 |
Publication |
Proceedings of the National Academy of Sciences of the United States of America |
Abbreviated Journal |
Proc. Natl. Acad. Sci. U.S.A. |
|
| |
Volume |
98 |
Issue |
9 |
Pages |
5359-5362 |
|
| |
Keywords |
Animals; Choice Behavior/physiology; Cognition/*physiology; Cues; Food Preferences/psychology; Macaca mulatta/*physiology/*psychology; Male; Memory/*physiology; Probability; Psychological Tests; Reproducibility of Results; Sensitivity and Specificity |
|
| |
Abstract |
Humans are consciously aware of some memories and can make verbal reports about these memories. Other memories cannot be brought to consciousness, even though they influence behavior. This conspicuous difference in access to memories is central in taxonomies of human memory systems but has been difficult to document in animal studies, suggesting that some forms of memory may be unique to humans. Here I show that rhesus macaque monkeys can report the presence or absence of memory. Although it is probably impossible to document subjective, conscious properties of memory in nonverbal animals, this result objectively demonstrates an important functional parallel with human conscious memory. Animals able to discern the presence and absence of memory should improve accuracy if allowed to decline memory tests when they have forgotten, and should decline tests most frequently when memory is attenuated experimentally. One of two monkeys examined unequivocally met these criteria under all test conditions, whereas the second monkey met them in all but one case. Probe tests were used to rule out “cueing” by a wide variety of environmental and behavioral stimuli, leaving detection of the absence of memory per se as the most likely mechanism underlying the monkeys' abilities to selectively decline memory tests when they had forgotten. |
|
| |
Address |
Section on the Neurobiology of Learning and Memory, Laboratory of Neuropsychology, National Institute of Mental Health, Building 49, Room 1B-80, Bethesda, MD 20892, USA. robert@ln.nimh.nih.gov |
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
|
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
0027-8424 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
PMID:11274360 |
Approved |
no |
|
| |
Call Number |
Equine Behaviour @ team @ |
Serial |
2824 |
|
| Permanent link to this record |
| |
|
| |
|
Author |
Sarter, M. |
|
| |
Title |
Animal cognition: defining the issues |
Type |
Journal Article |
| |
Year |
2004 |
Publication |
Neuroscience and Biobehavioral Reviews |
Abbreviated Journal |
Neurosci Biobehav Rev |
|
| |
Volume |
28 |
Issue |
7 |
Pages |
645-650 |
|
| |
Keywords |
Animals; Behavior, Animal/*physiology; Cognition/*physiology; Humans; *Models, Animal; Psychopharmacology/methods; Reproducibility of Results |
|
| |
Abstract |
The assessment of cognitive functions in rodents represents a critical experimental variable in many research fields, ranging from the basic cognitive neurosciences to psychopharmacology and neurotoxicology. The increasing use of animal behavioral tests as 'assays' for the assessment of effects on learning and memory has resulted in a considerable heterogeneity of data, particularly in the field of behavioral and psycho pharmacology. The limited predictive validity of changes in behavioral performance observed in standard animal tests of learning and memory indicates that a renewed effort to scrutinize the validity of these tests is warranted. In humans, levels of processing (effortful vs. automatic) and categories of information (procedural vs. episodic/declarative) are important variables of cognitive operations. The design of tasks that assess the recall of 'episodic' or 'declarative' information appears to represent a particular challenge for research using laboratory rodents. For example, the hypothesis that changes in inspection time for a previously encountered place or object are based on the recall of declarative/episodic information requires substantiation. In order to generalize findings on the effects of neuronal or pharmacological manipulations on learning and memory, obtained from one species and one task, to other species and other tasks, the mediating role of important sets of variables which influence learning and memory (e.g. attentional, affective) needs to be determined. Similar to the view that a neuronal manipulation (e.g. a lesion) represents a theory of the condition modeled (e.g. a degenerative disorder), an animal behavioral task represents a theory of the behavioral/cognitive process of interest. Therefore, the test of hypotheses regarding the validity of procedures used to assess cognitive functions in animals is an inherent part of the research process. |
|
| |
Address |
Department of Psychology, University of Michigan, 4032 East Hall, 525 E. University Avenue, Ann Arbor, MI 48109-1109, USA. msarter@umich.edu |
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
|
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
0149-7634 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
PMID:15555674 |
Approved |
no |
|
| |
Call Number |
Equine Behaviour @ team @ |
Serial |
2804 |
|
| Permanent link to this record |
| |
|
| |
|
Author |
Mateo, J.M.; Johnston, R.E. |
|
| |
Title |
Kin recognition by self-referent phenotype matching: weighing the evidence |
Type |
Journal Article |
| |
Year |
2003 |
Publication |
Animal Cognition |
Abbreviated Journal |
Anim. Cogn. |
|
| |
Volume |
6 |
Issue |
1 |
Pages |
73-76 |
|
| |
Keywords |
Animals; Brain/embryology; Cricetinae/embryology; Humans; Learning; Odors; Phenotype; *Recognition (Psychology); Reproducibility of Results; Research Design; *Self Psychology; *Smell |
|
| |
Abstract |
|
|
| |
Address |
Department of Psychology, Cornell University, NY 14853-7601, Ithaca, USA. jmateo@uchicago.edu |
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
|
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
1435-9448 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
PMID:12658537 |
Approved |
no |
|
| |
Call Number |
Equine Behaviour @ team @ |
Serial |
2579 |
|
| Permanent link to this record |
| |
|
| |
|
Author |
Machnik, M.; Hegger, I.; Kietzmann, M.; Thevis, M.; Guddat, S.; Schanzer, W. |
|
| |
Title |
Pharmacokinetics of altrenogest in horses |
Type |
Journal Article |
| |
Year |
2007 |
Publication |
Journal of Veterinary Pharmacology and Therapeutics |
Abbreviated Journal |
J Vet Pharmacol Ther |
|
| |
Volume |
30 |
Issue |
1 |
Pages |
86-90 |
|
| |
Keywords |
Administration, Oral; Animals; Chromatography, Liquid/veterinary; Doping in Sports/prevention & control; Horses/*metabolism; Male; Mass Spectrometry/veterinary; Progesterone Congeners/administration & dosage/blood/*pharmacokinetics/urine; Reproducibility of Results; Substance Abuse Detection/veterinary; Trenbolone/administration & dosage/*analogs & derivatives/blood/pharmacokinetics/urine |
|
| |
Abstract |
The Federation Equestre Internationale has permitted the use of altrenogest in mares for the control of oestrus. However, altrenogest is also suspicious to misuse in competition horses for its potential anabolic effects and suppression of typical male behaviour, and thus is a controlled drug. To investigate the pharmacokinetics of altrenogest in horses we conducted an elimination study. Five oral doses of 44 mug/kg altrenogest were administered to 10 horses at a dose interval of 24 h. Following administration blood and urine samples were collected at appropriate intervals. Altrenogest concentrations were measured by liquid chromatography-tandem mass spectrometry. The plasma levels of altrenogest reached maximal concentrations of 23-75 ng/mL. Baseline values were achieved within 3 days after the final administration. Urine peak concentrations of total altrenogest ranged from 823 to 3895 ng/mL. Twelve days after the final administration concentrations were below the limit of detection (ca 2 ng/mL). |
|
| |
Address |
Institute of Biochemistry, German Sport University, Cologne, Germany. m.machnik@biochem.dshs-koeln.de |
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
|
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
0140-7783 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
PMID:17217407 |
Approved |
no |
|
| |
Call Number |
|
Serial |
1841 |
|
| Permanent link to this record |
| |
|
| |
|
Author |
Staniar, W.B.; Kronfeld, D.S.; Hoffman, R.M.; Wilson, J.A.; Harris, P.A. |
|
| |
Title |
Weight prediction from linear measures of growing Thoroughbreds |
Type |
Journal Article |
| |
Year |
2004 |
Publication |
Equine veterinary journal |
Abbreviated Journal |
Equine Vet J |
|
| |
Volume |
36 |
Issue |
2 |
Pages |
149-154 |
|
| |
Keywords |
Animal Nutrition Physiology; Animals; Biometry; Body Weight/*physiology; Female; Horses/*anatomy & histology/*growth & development; Male; Mathematics; Predictive Value of Tests; Reproducibility of Results; Sensitivity and Specificity |
|
| |
Abstract |
REASON FOR PERFORMING STUDY: Monitoring weight of foals is a useful management practice to aid in maximising athletic potential while minimising risks associated with deviations from normal growth. OBJECTIVE: To develop predictive equations for weight, based on linear measurements of growing Thoroughbreds (TBs). METHODS: Morphometric equations predicting weight from measurements of the trunk and legs were developed from data of 153 foals. The accuracy, precision and bias of the best fitting equation were compared to published equations using a naive data set of 22 foals. RESULTS: Accuracy and precision were maximised with a broken line relating calculated volumes (V(t + l)) to measured weights. Use of the broken line is a 2 step process. V(t + l) is calculated from linear measures (m) of girth (G), carpus circumference (C), and length of body (B) and left forelimb (F). V(t + I) = ([G2 x B] + 4[C2 x F]) 4pi. If V(t + l) < 0.27 m3, weight is estimated: Weight (kg) = V(t + l) x 1093. If V(t + l) > or = 0.27 m3: Weight (kg) = V(t + l) x 984 + 24. The broken line was more accurate and precise than 3 published equations predicting the weight of young TBs. CONCLUSIONS: Estimation of weight using morphometric equations requires attention to temporal changes in body shape and density; hence, a broken line is needed. Including calculated leg volume in the broken line model is another contributing factor to improvement in predictive capability. POTENTIAL RELEVANCE: The broken line maximises its value to equine professionals through its accuracy, precision and convenience. |
|
| |
Address |
Department of Animal and Poultry Sciences, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061-0306, USA |
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
|
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
0425-1644 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
PMID:15038438 |
Approved |
no |
|
| |
Call Number |
|
Serial |
1806 |
|
| Permanent link to this record |
| |
|
| |
|
Author |
Gibson, B.M.; Shettleworth, S.J. |
|
| |
Title |
Place versus response learning revisited: tests of blocking on the radial maze |
Type |
Journal Article |
| |
Year |
2005 |
Publication |
Behavioral neuroscience |
Abbreviated Journal |
Behav Neurosci |
|
| |
Volume |
119 |
Issue |
2 |
Pages |
567-586 |
|
| |
Keywords |
Animals; *Association Learning; Male; *Maze Learning; Memory; Rats; Rats, Long-Evans; Reproducibility of Results |
|
| |
Abstract |
Neurobiological and behavioral research indicates that place learning and response learning occur simultaneously, in parallel. Such findings seem to conflict with theories of associative learning in which different cues compete for learning. The authors conducted place+response training on a radial maze and then tested place learning and response learning separately by reconfiguring the maze in various ways. Consistent with the effects of manipulating place and response systems in the brain (M. G. Packard & J. L. McGaugh, 1996), well-trained rats showed strong place learning and strong response learning. Three experiments using associative blocking paradigms indicated that prior response learning interferes with place learning. Blocking and related tests can be used to better understand how memory systems interact during learning. |
|
| |
Address |
Department of Psychology, University of New Hampshire, Durham, NH 03824-3567, USA. bgibson@cisunix.unh.edu |
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
|
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
0735-7044 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
PMID:15839803 |
Approved |
no |
|
| |
Call Number |
refbase @ user @ |
Serial |
362 |
|
| Permanent link to this record |
| |
|
| |
|
Author |
Lilienfeld, S.O.; Gershon, J.; Duke, M.; Marino, L.; de Waal, F.B. |
|
| |
Title |
A preliminary investigation of the construct of psychopathic personality (psychopathy) in chimpanzees (Pan troglodytes) |
Type |
Journal Article |
| |
Year |
1999 |
Publication |
Journal of comparative psychology (Washington, D.C. : 1983) |
Abbreviated Journal |
J Comp Psychol |
|
| |
Volume |
113 |
Issue |
4 |
Pages |
365-375 |
|
| |
Keywords |
Age Factors; Analysis of Variance; Animals; Antisocial Personality Disorder/*diagnosis/psychology; Ethology/*methods; Female; Male; Observer Variation; Pan troglodytes/*psychology; Psychiatric Status Rating Scales/*standards; Reproducibility of Results; Sex Characteristics; *Social Behavior |
|
| |
Abstract |
Although the construct of psychopathy has received considerable attention in humans, its relevance to other animals is largely unknown. We developed a measure of psychopathy for use in chimpanzees (Pan troglodytes), the Chimpanzee Psychopathy Measure (CPM), and asked 6 raters to complete this index on 34 chimpanzees. The CPM (a) demonstrated satisfactory interrater reliability and internal consistency; (b) exhibited marginally significant sex differences (males > females); (c) correlated positively with measures of extraversion, agreeableness, and observational ratings of agonism, sexual activity, daring behaviors, teasing, silent bluff displays, and temper tantrums, and negatively with observational ratings of generosity; and (d) demonstrated incremental validity above and beyond a measure of dominance. Although further validation of the CPM is needed, these findings suggest that the psychopathy construct may be relevant to chimpanzees. |
|
| |
Address |
Department of Psychology, Emory University, Atlanta, Georgia 30322, USA. scott@ss.emory.edu |
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
|
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
0735-7036 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
PMID:10608560 |
Approved |
no |
|
| |
Call Number |
refbase @ user @ |
Serial |
193 |
|
| Permanent link to this record |
