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Author (up) Ikeda, M.; Patterson, K.; Graham, K.S.; Ralph, M.A.L.; Hodges, J.R. doi  openurl
  Title A horse of a different colour: do patients with semantic dementia recognise different versions of the same object as the same? Type Journal Article
  Year 2006 Publication Neuropsychologia Abbreviated Journal Neuropsychologia  
  Volume 44 Issue 4 Pages 566-575  
  Keywords Adult; Aged; Anomia/diagnosis/psychology; Atrophy; *Attention; Color Perception; Dementia/*diagnosis/psychology; *Discrimination Learning; Dominance, Cerebral; Female; Humans; Male; *Memory, Short-Term; Middle Aged; Neuropsychological Tests; Orientation; *Pattern Recognition, Visual; Reference Values; Retention (Psychology); Semantics; Size Perception; Temporal Lobe/pathology  
  Abstract Ten patients with semantic dementia resulting from bilateral anterior temporal lobe atrophy, and 10 matched controls, were tested on an object recognition task in which they were invited to choose (from a four-item array) the picture representing “the same thing” as an object picture that they had just inspected and attempted to name. The target in the response array was never physically identical to the studied picture but differed from it – in the various conditions – in size, angle of view, colour or exemplar (e.g. a different breed of dog). In one test block for each patient, the response array was presented immediately after the studied picture was removed; in another block, a 2 min filled delay was inserted between study and test. The patients performed relatively well when the studied object and target response differed only in the size of the picture on the page, but were significantly impaired as a group in the other three type-of-change conditions, even with no delay between study and test. The five patients whose structural brain imaging revealed major right-temporal atrophy were more impaired overall, and also more affected by the 2 min delay, than the five patients with an asymmetric pattern characterised by predominant left-sided atrophy. These results are interpreted in terms of a hypothesis that successful classification of an object token as an object type is not a pre-semantic ability but rather results from interaction of perceptual and conceptual processing.  
  Address Department of Neuropsychiatry, Ehime University School of Medicine, Shitsukawa, Toon City, Ehime 791-0295, Japan. mikeda@m.ehime-u.ac.jp  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0028-3932 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:16115656 Approved no  
  Call Number Equine Behaviour @ team @ Serial 4059  
Permanent link to this record
 

 
Author (up) Stadler, P.; Rewel, A.; Deegen, E. openurl 
  Title [M-mode echocardiography in dressage horses, class S jumping horses and untrained horses] Type Journal Article
  Year 1993 Publication Zentralblatt fur Veterinarmedizin. Reihe A Abbreviated Journal Zentralbl Veterinarmed A  
  Volume 40 Issue 4 Pages 292-306  
  Keywords Animals; Echocardiography/*veterinary; Female; Heart Septum/ultrasonography; Heart Ventricles/ultrasonography; Horses/*anatomy & histology; Male; *Physical Conditioning, Animal; Reference Values  
  Abstract Heart structures of 45 warmblooded horses were measured by M-mode-echocardiography. The current training level of 15 dressage horses (group I) and 15 show-jumping horses (group II) was category “S”. In the third group were 15 untrained horses. Four standardized transducer positions were determined for the m-mode echobeam, calibrated according to the two-dimensional real time technique. End systolic and end diastolic diameters of left ventricle, right ventricle, aortic root, interventricular septum and left ventricular wall, as well as motion pattern of heart wall, mitral valve and aortic valve of all horses were measured. The dressage horses showed a significant thickening of interventricular septum and left-ventricular wall compared with the show-jumping horses and the untrained horses. The end diastolic left ventricle diameter of the show-jumping horses was significantly larger than in the other groups. Compared to the untrained horses the show-jumping horses showed a significantly larger end systolic left ventricular wall diameter measured at the level of papillary muscle. It can be concluded, that an increase in heart mass in category “S” sport horses is attributed to their level of training.  
  Address Klinik fur Pferde der Tierarztlichen Hochschule Hannover  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language German Summary Language Original Title Die M-mode-Echokardiographie bei S-Dressur-, S-Springpferden und bei untrainierten Pferden  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0514-7158 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:8342361 Approved no  
  Call Number Equine Behaviour @ team @ Serial 3749  
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Author (up) Sturz, B.R.; Bodily, K.D.; Katz, J.S. doi  openurl
  Title Evidence against integration of spatial maps in humans Type Journal Article
  Year 2006 Publication Animal Cognition Abbreviated Journal Anim. Cogn.  
  Volume 9 Issue 3 Pages 207-217  
  Keywords Adult; *Association Learning; Computer Graphics; Humans; Male; *Orientation; *Problem Solving; Reference Values; *Space Perception; *Spatial Behavior; User-Computer Interface  
  Abstract A dynamic 3-D virtual environment was constructed for humans as an open-field analogue of Blaisdell and Cook's (2005) pigeon foraging task to determine if humans, like pigeons, were capable of integrating separate spatial maps. Participants used keyboard keys and a mouse to search for a hidden goal in a 4x4 grid of raised cups. During Phase 1 training, a goal was consistently located between two landmarks (Map 1: blue T and red L). During Phase 2 training, a goal was consistently located down and left of a single landmark (Map 2: blue T). Transfer trials were then conducted in which participants were required to make choices in the presence of the red L alone. Cup choices during transfer assessed participants' strategies: association (from Map 1), generalization (from Map 2), or integration (combining Map 1 and 2). During transfer, cup choices increased to a location which suggested an integration strategy and was consistent with results obtained with pigeons. However, additional analyses of the human data suggested participants initially used a generalization strategy followed by a progressive shift in search behavior away from the red L. This shift in search behavior during transfer was responsible for the changes in cup choices across transfer trials and was confirmed by a control condition. These new analyses offer an alternative explanation to the spatial integration account proposed for pigeons.  
  Address Department of Psychology, Auburn University, Auburn, AL 36849, USA. sturzbr@auburn.edu  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1435-9448 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:16767470 Approved no  
  Call Number Equine Behaviour @ team @ Serial 2464  
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Author (up) Touma, C.; Sachser, N.; Mostl, E.; Palme, R. openurl 
  Title Effects of sex and time of day on metabolism and excretion of corticosterone in urine and feces of mice Type Journal Article
  Year 2003 Publication General and Comparative Endocrinology Abbreviated Journal Gen Comp Endocrinol  
  Volume 130 Issue 3 Pages 267-278  
  Keywords Animals; Chromatography, High Pressure Liquid; Circadian Rhythm/*physiology; Corticosterone/*metabolism/urine; Feces/*chemistry; Female; Immunoenzyme Techniques; Kinetics; Male; Mice; Mice, Inbred C57BL; Reference Values; Sex Factors; Stress/metabolism; Time Factors; Tritium  
  Abstract Non-invasive techniques to monitor stress hormones in small animals like mice offer several advantages and are highly demanded in laboratory as well as in field research. Since knowledge about the species-specific metabolism and excretion of glucocorticoids is essential to develop such a technique, we conducted radiometabolism studies in mice (Mus musculus f. domesticus, strain C57BL/6J). Each mouse was injected intraperitoneally with 740 kBq of 3H-labelled corticosterone and all voided urine and fecal samples were collected for five days. In a first experiment 16 animals (eight of each sex) received the injection at 9 a.m., while eight mice (four of each sex) were injected at 9 p.m. in a second experiment. In both experiments radioactive metabolites were recovered predominantly in the feces, although males excreted significantly higher proportions via the feces (about 73%) than females (about 53%). Peak radioactivity in the urine was detected within about 2h after injection, while in the feces peak concentrations were observed later (depending on the time of injection: about 10h postinjection in experiment 1 and about 4h postinjection in experiment 2, thus proving an effect of the time of day). The number and relative abundance of fecal [3H]corticosterone metabolites was determined by high performance liquid chromatography (HPLC). The HPLC separations revealed that corticosterone was extensively metabolized mainly to more polar substances. Regarding the types of metabolites formed, significant differences were found between males and females, but not between the experiments. Additionally, the immunoreactivity of these metabolites was assessed by screening the HPLC fractions with four enzyme immunoassays (EIA). However, only a newly established EIA for 5alpha-pregnane-3beta,11beta,21-triol-20-one (measuring corticosterone metabolites with a 5alpha-3beta,11beta-diol structure) detected several peaks of radioactive metabolites with high intensity in both sexes, while the other EIAs showed only minor immunoreactivity. Thus, our study for the first time provides substantial information about metabolism and excretion of corticosterone in urine and feces of mice and is the first demonstrating a significant impact of the animals' sex and the time of day. Based on these data it should be possible to monitor adrenocortical activity non-invasively in this species by measuring fecal corticosterone metabolites with the newly developed EIA. Since mice are extensively used in research world-wide, this could open new perspectives in various fields from ecology to behavioral endocrinology.  
  Address Department of Behavioral Biology, Institute of Neuro and Behavioral Biology, University of Muenster, Badestrasse 9, D-48149 Muenster, Germany. touma@uni-muenster.de  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0016-6480 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:12606269 Approved no  
  Call Number Equine Behaviour @ team @ Serial 4086  
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Author (up) van der Kolk, J.H.; Nachreiner, R.F.; Schott, H.C.; Refsal, K.R.; Zanella, A.J. openurl 
  Title Salivary and plasma concentration of cortisol in normal horses and horses with Cushing's disease Type Journal Article
  Year 2001 Publication Equine Veterinary Journal Abbreviated Journal Equine Vet J  
  Volume 33 Issue 2 Pages 211-213  
  Keywords Adrenal Cortex Function Tests/standards/veterinary; Animals; Cushing Syndrome/diagnosis/metabolism/*veterinary; Female; Horse Diseases/blood/*diagnosis/metabolism; Horses/blood/*metabolism; Hydrocortisone/blood/*metabolism; Male; Predictive Value of Tests; Reference Values; Saliva/*metabolism  
  Abstract  
  Address Department of Large Animal Medicine and Nutrition, Veterinary Faculty, Utrecht University, The Netherlands  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0425-1644 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:11266074 Approved no  
  Call Number Equine Behaviour @ team @ Serial 4281  
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